Explore top 2025 4 Star Hotels in Central San Diego

Start date: Check-in selected.
End date: Check-out

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Top Central San Diego 4 Star hotels

San Diego Marriott La Jolla

San Diego Marriott La Jolla

4 out of 5
4240 La Jolla Village Dr, La Jolla, CA
$163 nightly
The price is $188 total per night from Sep 12 to Sep 13
$188 total
Sep 12 - Sep 13
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
San Diego Marriott La Jolla
Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

4 out of 5
1433 Camino Del Rio S, San Diego, CA
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $146 total per night from Sep 14 to Sep 15
$146 total
Sep 14 - Sep 15
Total with taxes and fees
This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Sheraton Mission Valley San Diego Hotel
Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla

4 out of 5
4550 La Jolla Village Dr, San Diego, CA
$194 nightly
The price is $223 total per night from Sep 28 to Sep 29
$223 total
Sep 28 - Sep 29
Total with taxes and fees
This traditional hotel includes 2 restaurants, an indoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and WiFi in ...
Embassy Suites by Hilton San Diego La Jolla
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S, San Diego, CA
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $144 total per night from Sep 21 to Sep 22
$144 total
Sep 21 - Sep 22
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Hilton San Diego Mission Valley
Lafayette Hotel & Club

Lafayette Hotel & Club

4 out of 5
2223 El Cajon Blvd, San Diego, CA
Fully refundableReserve now, pay when you stay
$226 nightly
The price is $259 total per night from Sep 11 to Sep 12
$259 total
Sep 11 - Sep 12
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...
Lafayette Hotel & Club
Town and Country San Diego

Town and Country San Diego

4 out of 5
500 Hotel Circle North, San Diego, CA
Fully refundableReserve now, pay when you stay
$279 nightly
The price is $321 total per night from Sep 20 to Sep 21
$321 total
Sep 20 - Sep 21
Total with taxes and fees
This hotel features 2 restaurants, 2 outdoor pools, and a hot tub. Bring the family and enjoy the children's pool, waterslide, and playground. Enjoy the gym ...
Town and Country San Diego
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South, San Diego, CA
Fully refundableReserve now, pay when you stay
$146 nightly
The price is $168 total per night from Sep 22 to Sep 23
$168 total
Sep 22 - Sep 23
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
Legacy Resort Hotel & Spa
Hyatt Regency La Jolla

Hyatt Regency La Jolla

4 out of 5
3777 La Jolla Village Drive, San Diego, CA
$265 nightly
The price is $304 total per night from Sep 28 to Sep 29
$304 total
Sep 28 - Sep 29
Total with taxes and fees
2 outdoor tennis courts, an outdoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
Hyatt Regency La Jolla
San Diego Marriott Mission Valley

San Diego Marriott Mission Valley

4 out of 5
8757 Rio San Diego Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $183 total per night from Sep 29 to Sep 30
$183 total
Sep 29 - Sep 30
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 30 conference rooms, business center, and express ...
San Diego Marriott Mission Valley
DoubleTree by Hilton San Diego - Hotel Circle

DoubleTree by Hilton San Diego - Hotel Circle

4 out of 5
1515 Hotel Cir S, San Diego, CA
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $144 total per night from Sep 21 to Sep 22
$144 total
Sep 21 - Sep 22
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
DoubleTree by Hilton San Diego - Hotel Circle
Don't see what you're looking for?
See all available properties in Central San Diego
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Central San Diego

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Central San Diego 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Central San Diego will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Central San Diego, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.