Book a hotel near Mission Bay, San Diego

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Top hotels close to Mission Bay

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Free Cancellation
Reserve now, pay when you stay
0.74 mi from Mission Bay
$174 nightly
The price is $200 total per night
$200 total
Dec 16 - Dec 17
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 2 restaurants. Family-friendly amenities include mini golf and kid-friendly dining, along with kayaking. Enjoy the 5 outdoor pools and perks like free WiFi.
Pool
Hot Tub
San Diego Mission Bay Resort

San Diego Mission Bay Resort

4 out of 5
1775 E Mission Bay Dr San Diego CA
Free Cancellation
Reserve now, pay when you stay
0.98 mi from Mission Bay
$218 nightly
The price is $251 total per night
$251 total
Dec 9 - Dec 10
Total with taxes and fees
A full-service spa, 2 restaurants, and 5 outdoor tennis courts are all featured at this Mediterranean hotel. There's fun for all ages with a children's pool and an arcade/game room, and families will appreciate the picnic area. Enjoy the outdoor pool and perks like free WiFi.
Pool
Hot Tub
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
Free Cancellation
Reserve now, pay when you stay
1.05 mi from Mission Bay
$166 nightly
The price is $191 total per night
$191 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
A marina, 2 outdoor pools, and 2 hot tubs are all featured at this smoke-free hotel. If you want to take your pet along, this pet-friendly property offers everything you'll need for your pet including food and water bowls. 2 poolside bars, a bar/lounge, and restaurant offer options for drinks and a bit to eat.
Pool
Hot Tub
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

4 out of 5
1441 Quivira Rd San Diego CA
Free Cancellation
Reserve now, pay when you stay
1.15 mi from Mission Bay
$162 nightly
The price is $186 total per night
$186 total
Dec 18 - Dec 19
Total with taxes and fees
This smoke-free hotel features a full-service spa, a marina, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Enjoy the 3 outdoor pools and gym, and unwind with a drink at the bar/lounge.
Pool
Hot Tub
Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
Free Cancellation
Reserve now, pay when you stay
1.24 mi from Mission Bay
$175 nightly
The price is $202 total per night
$202 total
Dec 17 - Dec 18
Total with taxes and fees
2 outdoor tennis courts, an outdoor pool, and a hot tub are all featured at this smoke-free resort. Spend a day at the beach surfing, or relax with free beach cabanas and sun loungers. Traveling for business? Take advantage of the business center, express check-out, and conference space.
Pool
Hot Tub
Heritage Inn San Diego

Heritage Inn San Diego

2 out of 5
3333 Channel Way San Diego CA
Free Cancellation
1.53 mi from Mission Bay
$57 nightly
The price is $66 total per night
$66 total
Dec 28 - Dec 29
Total with taxes and fees
An outdoor pool is featured at this hotel, along with free self parking. WiFi in public areas is free. Luggage storage is also provided.
Pool
Pet friendly
Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld

3 out of 5
3737 Sports Arena Blvd San Diego CA
1.74 mi from Mission Bay
$85 nightly
The price is $97 total per night
$97 total
Dec 14 - Dec 15
Total with taxes and fees
An outdoor pool, self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Traveling on business? Take advantage of the 3 conference rooms, business center, and express check-out.
Pool
Free WiFi
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
3999 Mission Boulevard San Diego CA
Free Cancellation
Reserve now, pay when you stay
1.78 mi from Mission Bay
$189 nightly
The price is $218 total per night
$218 total
Jan 6 - Jan 7, 2026
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free resort. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Bring the family and enjoy the arcade/game room, along with kayaking.
Pool
Hot Tub
GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay

2.5 out of 5
4540 Mission Bay Drive San Diego CA
Free Cancellation
Reserve now, pay when you stay
1.84 mi from Mission Bay
$94 nightly
The price is $108 total per night
$108 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included
Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

3 out of 5
3888 Greenwood St San Diego CA
Free Cancellation
Reserve now, pay when you stay
1.96 mi from Mission Bay
$119 nightly
The price is $137 total per night
$137 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features an outdoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the hot tub and free buffet breakfast each morning.
Pool
Hot Tub
Comfort Inn Sea World Area

Comfort Inn Sea World Area

3.5 out of 5
3880 Greenwood St San Diego CA
Free Cancellation
Reserve now, pay when you stay
1.97 mi from Mission Bay
$85 nightly
The price is $98 total per night
$98 total
Dec 17 - Dec 18
Total with taxes and fees
A gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like buffet breakfast and WiFi in public areas. There's a snack bar/deli and multilingual staff can provide around-the-clock assistance.
Breakfast included
Pet friendly
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

2.5 out of 5
2151 Hotel Circle South San Diego CA
Free Cancellation
Reserve now, pay when you stay
2.88 mi from Mission Bay
$101 nightly
The price is $116 total per night
$116 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the free on-the-go breakfast each morning.
Pool
Breakfast included
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mission Bay hotels essential information

Accommodation
7,542 hotels
Lowest Price
$66
Highest Price
$251
Popular hotels
The Dana on Mission Bay, Paradise Point Resort & Spa, Hyatt Regency Mission Bay Spa and Marina, San Diego Mission Bay Resort, Wyndham Garden San Diego Near SeaWorld, Hampton Inn & Suites by Hilton San Diego SeaWorld, Bahia Resort Hotel, GreenTree Inn San Diego Mission Bay, Comfort Inn Sea World Area, Hampton Inn San Diego/Mission Valley, Catamaran Resort and Spa, Heritage Inn San Diego

Recent Mission Bay hotel reviews by fellow wanderers

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld

5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Lovely coffee, and the office lounge was a pleasant place to read while waiting for the others to wake up. Really spacious room and bath and great TV channels. It was perfect having a fridge, microwave, and coffee-maker because we shopped for food and ate out a lot. Nice walking-distance selection of food in all directions!"
A verified traveler stayed at Wyndham Garden San Diego Near SeaWorld
Wyndham Garden San Diego Near SeaWorld

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