Find a Hotel in Serra Mesa
Seize Your Someday with our amazing deals for the whole family!
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Top hotels in Serra Mesa

Wyndham San Diego Bayside
"Checking in was an absolute nightmare. Staff directed us to the parking structure without letting us unload our luggage. We proceeded to the parking structure only to realize that there was no elevator. Staff that directed us did not tell us that there was no elevator. Once we made it to the lobby ..."
Reviewed on Nov 10, 2026

Handlery Hotel
"This property had such a cool, vintage California feel. Even though it is an old building, things were well kept up and clean. The beds were comfortable and I was glad the room had a coffee maker and a safe. The restaurant on site was good and all employees I interacted with were friendly. Parking ..."
Reviewed on Nov 10, 2026

California Suites Hotel
"Pleasant stay"
Reviewed on Nov 9, 2026

Best Western Seven Seas
"Everything was good till"
Reviewed on Nov 10, 2026

Hard Rock Hotel San Diego

Paradise Point Resort & Spa

Sheraton San Diego Resort

Days Inn by Wyndham San Diego Hotel Circle

The Sofia Hotel
Serra Mesa Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Serra Mesa area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Serra Mesa to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Serra Mesa are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Serra Mesa hotel reviews by fellow wanderers

Hotel del Coronado, Curio Collection by Hilton
"Plan your trip by going on line and making reservations prior to your visit"
More ways to wander Serra Mesa
Explore More Ways to Travel with Travelocity
- Marina District Hotels
- Hotels near Marine Corps Air Station Miramar
- Hotels near San Diego Zoo Safari Park
- Hotels near San Diego Zoo
- Hotels near San Diego State University
- Hotels near University Of San Diego
- Hotels near Westfield Utc
- Village Of La Jolla Hotels
- Hotels near Va Medical Center
- Hotels near Uss Midway Museum
- Hotels near The Rady Shell At Jacobs Park
- Tierrasanta Hotels
- Hotels near Torrey Pines Golf Course
- Hotels near Marine Corps Recruit Depot
- Miramar Hotels
- Hotels near Mission Basilica San Diego De Alcala
- Hotels near Mission Bay
- Hotels near Mission Bay Park
- Hotels near Mission Beach Boardwalk
- Hotels near Mission Beach
- Mission Beach Hotels
- Mission Hills Hotels
- Mission Valley Hotels
- Hotels near San Diego Ca
- Hotels in National City
- Hotels near Naval Base San Diego
- Hotels near Navy Pier
- North Park Hotels
- Hotels near Ocean Beach Pier
- Ocean Beach Hotels
- Hotels in Oceanside
- Hotels near Old Town San Diego State Park
- Pacific Beach Hotels
- Hotels near Pechanga Arena
- Hotels near Petco Park
- Point Loma Hotels
- Hotels near Port Of San Diego
- Hotels in Poway
- Torrey Pines Hotels
- University Heights Hotels
- Hotels in Rancho Santa Fe
- Hotels near Riverwalk Golf Club
- Hotels near San Diego Civic Theatre
- Hotels near San Diego Convention Center
- Hotels in San Diego
- Hotels near San Diego Ca
- Hotels near B Street Cruise Ship Terminal
- Hotels near Balboa Park
- Bankers Hill Hotels
- Barrio Logan Hotels
- Hotels near Belmont Park
- Hotels near Birch Aquarium
- Hotels in Bonita
- Hotels in Cardiff-By-The-Sea
- Carmel Valley Hotels
- Hotels near Chicano Park
- Hotels near Chula Vista Center
- Hotels in Chula Vista
- City Heights Hotels
- Clairemont Hotels
- Hotels in Coronado
- Hotels near Crystal Pier
- Hotels near Del Mar Fairgrounds
- Hotels in Del Mar
- Hotels near Del Mar Racetrack
- San Diego County Hotels
- Downtown San Diego Hotels
- Hotels in El Cajon
- Hotels near Fashion Valley Mall
- Gaslamp Quarter Hotels
- Harbor Island Hotels
- Hillcrest Hotels
- Hotels near Hotel Circle
- Hotels near Hotel Del Coronado
- Hotels near Humphreys Concerts By The Bay
- Kearny Mesa Hotels
- Kensington Hotels
- Hotels near La Jolla Beach
- Hotels in La Jolla
- Hotels in Santee
- Hotels near Scripps Memorial Hospital La Jolla
- Scripps Ranch Hotels
- Hotels near Seaport Village
- Hotels near Snapdragon Stadium
- Hotels in Solana Beach
- Sorrento Valley Hotels
- South Park Hotels
- Hotels in Spring Valley
- La Jolla Shores Hotels
- La Jolla Village Hotels
- Hotels in La Mesa
- Hotels in Lakeside
- Lawrence Welk Resort Village Hotels
- Hotels in Lemon Grove
- Liberty Station Hotels
- Lincoln Park Hotels
- Linda Vista Hotels





