Find a Hotel in Serra Mesa
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Top hotels in Serra Mesa

Wyndham San Diego Bayside
"Well it took forever to get checked in at 3:00 pm. The room was clean but we didn’t have enough towels for the 4 people staying in the room. If it wasn’t for the location being right across for the pier I would have giving it a 2 star rating."
Reviewed on Nov 8, 2026

Handlery Hotel
"Clean Room and parking was good."
Reviewed on Nov 8, 2026

California Suites Hotel
"The property is beautiful and the staff is wonderful😊 We loved the landscaping and the clean well appointed room. We had been in contact with the motel many times- and they did give us an upstairs room- however the only choice was a room with no view on the road- very noisy😳 We understand it is ..."
Reviewed on Nov 8, 2026

Days Inn by Wyndham San Diego Hotel Circle
"Nice big clean rooms"
Reviewed on Nov 7, 2026

Hard Rock Hotel San Diego

Paradise Point Resort & Spa

Best Western Seven Seas

Sheraton San Diego Resort

The Sofia Hotel
Serra Mesa Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Serra Mesa area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Serra Mesa to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Serra Mesa are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Serra Mesa hotel reviews by fellow wanderers

Wyndham San Diego Bayside
"Well it took forever to get checked in at 3:00 pm. The room was clean but we didn’t have enough towels for the 4 people staying in the room. If it wasn’t for the location being right across for the pier I would have giving it a 2 star rating."
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