Book Hotels in Central San Diego, CA

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Top Central San Diego hotels

Lafayette Hotel & Club

Lafayette Hotel & Club

4 out of 5
2223 El Cajon Blvd San Diego CA
Fully refundableReserve now, pay when you stay
$249 nightly
The price is $286 total per night from May 18 to May 19
$286 total
May 18 - May 19
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...
Breakfast on the terrace was wonderful. Great vibe and great food.

Reviewed on May 13, 2026

Opens in a new windowLafayette Hotel & Club
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S San Diego CA
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $125 total per night from May 25 to May 26
$125 total
May 25 - May 26
Total with taxes and fees
This Art Deco hotel includes 2 restaurants, an outdoor pool, and a hot tub. Enjoy the gym and perks like free WiFi. A bar/lounge, a 24-hour front desk, and a ...
Almost got the poolside room but weather was looking bad so I opted for the "executive suite" with the king bed. They put me all the way in the back above the kitchen. Had a balcony but it was next to the exhaust fans. View of the parking lot and a bunch of industrial kitchen equipment that hummed ...

Reviewed on May 14, 2026

Opens in a new windowKings Inn San Diego
San Diego Marriott Mission Valley

San Diego Marriott Mission Valley

4 out of 5
8757 Rio San Diego Dr San Diego CA
Fully refundableReserve now, pay when you stay
$164 nightly
The price is $189 total per night from May 25 to May 26
$189 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 30 conference rooms, business center, and express ...
The vent in the room was dirty. The wall paper was peeling. The floor in the elevator was dirty.

Reviewed on May 12, 2026

Opens in a new windowSan Diego Marriott Mission Valley
Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

4 out of 5
1433 Camino Del Rio S San Diego CA
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $175 total per night from May 21 to May 22
$175 total
May 21 - May 22
Total with taxes and fees
This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
👍

Reviewed on May 11, 2026

Opens in a new windowSheraton Mission Valley San Diego Hotel
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $148 total per night from May 25 to May 26
$148 total
May 25 - May 26
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
Very nice and clean. The only thing, and this is small, the closet door was off the track and the refrigerator wasnt very cool.but in the positive, we got clean towels every day!

Reviewed on May 14, 2026

Opens in a new windowHandlery Hotel
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $97 total per night from May 17 to May 18
$97 total
May 17 - May 18
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...
Staff was great. Had to switch rooms because the first one reeked of pee. Second one smelt old but better than pee. The outside area also smells of pee

Reviewed on May 13, 2026

Opens in a new windowDays Inn by Wyndham San Diego Hotel Circle
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

2.5 out of 5
2485 Hotel Circle Place San Diego CA
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $146 total per night from May 27 to May 28
$146 total
May 27 - May 28
Total with taxes and fees
This hotel features an outdoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the hot tub and free full breakfast ...
Clean and very nice. Can’t complain.

Reviewed on May 14, 2026

Opens in a new windowBest Western Inn & Suites San Diego – Zoo/SeaWorld Area
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $94 total per night from May 19 to May 20
$94 total
May 19 - May 20
Total with taxes and fees
2 hot tubs, an outdoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi ...
100 recommendations

Reviewed on May 13, 2026

Opens in a new windowBest Western Seven Seas
California Suites Hotel

California Suites Hotel

2 out of 5
5415 Clairemont Mesa Blvd San Diego CA
Fully refundableReserve now, pay when you stay
$86 nightly
The price is $99 total per night from May 20 to May 21
$99 total
May 20 - May 21
Total with taxes and fees
This hotel features an outdoor pool and a hot tub. Traveling for business? Take advantage of the free WiFi in public areas, express check-out, and conference ...
The area is a bit noisy but OK when the windows are closed. I like the fact you can open the windows. Walking distance to many eateries. Overall I enjoyed my visit and would stay here again.

Reviewed on May 14, 2026

Opens in a new windowCalifornia Suites Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Central San Diego hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Central San Diego Hotel & Travel Guide\n

You can discover a wide variety of apartment and hotel options to choose from in Central San Diego. Travelocity's booking page currently is where you will find 51 hotel establishments within a 6-mile (10-kilometer) distance of downtown Central San Diego.

You'll find Residence Inn By Marriott San Diego Central and Hampton Inn San Diego-Kearny Mesa within wandering distance of Central San Diego's city center.

Students, families and those watching their dollars will find some great Central San Diego accommodation options that won't blow holes in the wallet. The Extended Stay America San Diego - Mission Valley - Stadium and the Quality Inn San Diego Miramar are amongst the other cheaper hotels worth investigating.

The Rancho Valencia Resort and Spa is located 10 miles (16 kilometers) away from central Central San Diego. Another place to stay is the Fairmont Grand Del Mar, which is 7 miles (11 kilometers) away. The Hotel del Coronado along with the Pantai Inn are alternate bases around Central San Diego.

If time is on your side, why not broaden your horizons and get to know the many other attractions around Southern California during your stay in the area? Southern California offers beaches, mountains and rolling hills, and interesting tourist places of interest are art galleries, open-air exhibits and street art. Modern visitors in this part of United States of America commonly enjoy snowboarding.

Looking for more activities? Consider spending a few hours enjoying Centennial Park and Coronado Ferry Landing, which you'll find in Coronado, 13 miles (21 kilometers) south of Central San Diego. The Marriott Coronado Island Resort & Spa and Hard Rock Hotel San Diego are just some examples of the apartment and hotel choices in Coronado. Or stay in Carlsbad, 20 miles (34 kilometers) to the northwest of Central San Diego, where you can choose between the Four Seasons Residence Club Aviara, North San Diego and Park Hyatt Aviara Resort, Spa & Golf Club. Whether you're just passing through or staying in Carlsbad, set aside some time to visit the Carlsbad Premium Outlets and Carlsbad State Beach.

San Diego International Airport is a practical gateway for air travel, and can be found 9 miles (15 kilometers) away from downtown Central San Diego. Conveniently located Travelocity-listed hotels include Paradise Point Resort & Spa and San Diego Marriott Gaslamp Quarter.

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