Explore top 2026 4 Star Hotels in Central San Diego

Start date: Check-in selected.
To Date
End date: Check-out

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Next weekend

Top Central San Diego 4 Star hotels

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

4 out of 5
7450 Hazard Center Dr San Diego CA
$151 nightly
The price is $173 total per night from Feb 25 to Feb 26
$173 total
Feb 25 - Feb 26
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 20 conference rooms, free WiFi in public areas, ...
8.2/10 Very Good! (1,506 reviews)
Very nice room. Clean and well appointed amenities. The staff was very friendly upon check-in and even the next say when i asked for directions to the restaurant for breakfast.

Reviewed on Jan 28, 2026

Opens in a new windowDoubleTree by Hilton Hotel San Diego - Mission Valley
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S San Diego CA
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $147 total per night from Feb 5 to Feb 6
$147 total
Feb 5 - Feb 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
8/10 Very Good! (2,312 reviews)
Staff was helpful

Reviewed on Jan 31, 2026

Opens in a new windowHilton San Diego Mission Valley
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $229 total per night from Feb 8 to Feb 9
$229 total
Feb 8 - Feb 9
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9/10 Wonderful! (2,937 reviews)
They dont mention u s$38 per day for parking Empty parking lot!! Also too many texts selling spa services with automatic 22% service charge!!!!

Reviewed on Jan 27, 2026

Opens in a new windowLegacy Resort Hotel & Spa
Lafayette Hotel & Club

Lafayette Hotel & Club

4 out of 5
2223 El Cajon Blvd San Diego CA
Fully refundableReserve now, pay when you stay
$229 nightly
The price is $263 total per night from Feb 5 to Feb 6
$263 total
Feb 5 - Feb 6
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...
9.2/10 Wonderful! (1,449 reviews)
Unique place to stay

Reviewed on Jan 28, 2026

Opens in a new windowLafayette Hotel & Club
Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

4 out of 5
1433 Camino Del Rio S San Diego CA
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $155 total per night from Feb 7 to Feb 8
$155 total
Feb 7 - Feb 8
Total with taxes and fees
This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
8.4/10 Very Good! (1,718 reviews)
Great staff and room service

Reviewed on Jan 28, 2026

Opens in a new windowSheraton Mission Valley San Diego Hotel
Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla

4 out of 5
4550 La Jolla Village Dr San Diego CA
Fully refundableReserve now, pay when you stay
$178 nightly
The price is $204 total per night from Feb 7 to Feb 8
$204 total
Feb 7 - Feb 8
Total with taxes and fees
This traditional hotel includes 2 restaurants, an indoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and WiFi in ...
8.8/10 Excellent! (1,846 reviews)
Great included breakfast!

Reviewed on Jan 30, 2026

Opens in a new windowEmbassy Suites by Hilton San Diego La Jolla
San Diego Marriott Mission Valley

San Diego Marriott Mission Valley

4 out of 5
8757 Rio San Diego Dr San Diego CA
Fully refundableReserve now, pay when you stay
$164 nightly
The price is $189 total per night from Mar 1 to Mar 2
$189 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 30 conference rooms, business center, and express ...
8.6/10 Excellent! (1,000 reviews)
Room was clean. Had a bit of an odor in it. Like if open beer cans were left out and you woke up next morning. Plus a bit of trash in wardrope, house keeping forgot to throw away

Reviewed on Jan 19, 2026

Opens in a new windowSan Diego Marriott Mission Valley
Hyatt Regency La Jolla

Hyatt Regency La Jolla

4 out of 5
3777 La Jolla Village Drive San Diego CA
Fully refundableReserve now, pay when you stay
$197 nightly
The price is $226 total per night from Feb 8 to Feb 9
$226 total
Feb 8 - Feb 9
Total with taxes and fees
2 outdoor tennis courts, an outdoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
8.8/10 Excellent! (1,001 reviews)
The room was clean and we got a free upgrade to a larger room. The only downside is it's a pain to walk anywhere, though it is close enough to the Nobel and UTC Blue Line stops and the rapid loop buses.

Reviewed on Jan 20, 2026

Opens in a new windowHyatt Regency La Jolla
San Diego Marriott La Jolla

San Diego Marriott La Jolla

4 out of 5
4240 La Jolla Village Dr La Jolla CA
Fully refundableReserve now, pay when you stay
$163 nightly
The price is $188 total per night from Feb 6 to Feb 7
$188 total
Feb 6 - Feb 7
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
8.4/10 Very Good! (2,247 reviews)
it was nice and the staff were genuine and warm

Reviewed on Jan 27, 2026

Opens in a new windowSan Diego Marriott La Jolla
DoubleTree by Hilton San Diego - Hotel Circle

DoubleTree by Hilton San Diego - Hotel Circle

4 out of 5
1515 Hotel Cir S San Diego CA
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $141 total per night from Feb 15 to Feb 16
$141 total
Feb 15 - Feb 16
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
7.2/10 Good! (1,834 reviews)
La bañera esta sucia, con oxido y el piso manchado

Reviewed on Feb 1, 2026

Opens in a new windowDoubleTree by Hilton San Diego - Hotel Circle
Don't see what you're looking for?
See all available properties in Central San Diego
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Central San Diego

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Central San Diego 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Central San Diego will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Central San Diego, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Central San Diego hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity