Find and compare 3 Star hotels in Otay Mesa

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Top Otay Mesa 3 Star hotels

Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $84 total per night from Apr 1 to Apr 2
$84 total
Apr 1 - Apr 2
Total with taxes and fees
2 hot tubs, an outdoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi ...
7.8/10 Good! (3,284 reviews)
Family friendly. Restaurant was delicious. friendly staff

Reviewed on Mar 13, 2026

Opens in a new windowBest Western Seven Seas
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $126 total per night from Apr 13 to Apr 14
$126 total
Apr 13 - Apr 14
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
8.2/10 Very Good! (2,334 reviews)
Incredibly nice pool and hot tub, feels like you’re at a resort. Breakfast at the restaurant was delicious and reasonable. Easy access in and out of hotel. Room was clean and nice, and the price was fabulous. I enjoy boutique hotels over chain hotels and this one didn’t disappoint.

Reviewed on Mar 11, 2026

Opens in a new windowHandlery Hotel
The Bristol Hotel San Diego

The Bristol Hotel San Diego

3.5 out of 5
1055 1st Ave San Diego CA
Fully refundableReserve now, pay when you stay
$141 nightly
The price is $164 total per night from Apr 3 to Apr 4
$164 total
Apr 3 - Apr 4
Total with taxes and fees
A gym is featured at this hotel, along with valet parking. WiFi in public areas is free. A business center, a snack bar/deli, and a grocery/convenience store ...
8.6/10 Excellent! (1,521 reviews)
The Bristol fit my needs as a work traveler and use of city's convention center. It was a healthy walk to convention halls but weather was beautiful for it. I used city bus from airport and easy with stop close to hotel. Light rails also close by. Hotel a few blocks off main Gaslamp hustle bustle. ...

Reviewed on Mar 10, 2026

Opens in a new windowThe Bristol Hotel San Diego
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $123 total per night from Apr 5 to Apr 6
$123 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...
8/10 Very Good! (2,541 reviews)
Nice staff

Reviewed on Mar 14, 2026

Opens in a new windowDays Inn by Wyndham San Diego Hotel Circle
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $150 total per night from Apr 5 to Apr 6
$150 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9/10 Wonderful! (1,190 reviews)
The staff was knowledgeable and friendly. The hotel was clean. The room was basic. It had a fridge but no microwave. It's walking distance many restaurants and the piers. It's also convenient to get th Balboa Park and the airport.

Reviewed on Mar 13, 2026

Opens in a new windowThe DEXTRO Little Italy, BW Premier Collection
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
Fully refundableReserve now, pay when you stay
$160 nightly
The price is $186 total per night from Apr 7 to Apr 8
$186 total
Apr 7 - Apr 8
Total with taxes and fees
A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
8.6/10 Excellent! (1,805 reviews)
Room was clean & customer service was incredible. Shower water was cold but the staff is so nice that I’m sure they’d address the sure if you present it to them. I only stayed one night

Reviewed on Mar 14, 2026

Opens in a new windowThe Sofia Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
$189 nightly
The price is $217 total per night from Apr 5 to Apr 6
$217 total
Apr 5 - Apr 6
Total with taxes and fees
A marina, 2 outdoor pools, and 2 hot tubs are all featured at this smoke-free hotel. If you want to take your pet along, this pet-friendly property offers everything ...
9/10 Wonderful! (4,145 reviews)
Front desk was nice , housekeeping for the first 2 days was so sweet they made animal shapes out of towels for the kids when we got back to the room at the end of the night

Reviewed on Mar 12, 2026

Opens in a new windowThe Dana on Mission Bay
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $171 total per night from Mar 15 to Mar 16
$171 total
Mar 15 - Mar 16
Total with taxes and fees
A marina, a gym, and a restaurant are all featured at this traditional hotel. Traveling on business? Take advantage of the free WiFi in public areas and free ...
9.2/10 Wonderful! (3,472 reviews)
Everything is nice. The property is super old though and should probably be completely renovated, but I had a blast.

Reviewed on Mar 13, 2026

Opens in a new windowBay Club Hotel & Marina
Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina

3 out of 5
2051 Shelter Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
$151 nightly
The price is $174 total per night from Apr 5 to Apr 6
$174 total
Apr 5 - Apr 6
Total with taxes and fees
A marina, 2 outdoor pools, and 2 outdoor tennis courts are all featured at this smoke-free hotel. Enjoy the 2 hot tubs and perks like free WiFi. A gym, a restaurant, ...
8.8/10 Excellent! (1,592 reviews)
Very easy and quick check in, our room was nice size and clean. We wasn’t told about anything that goes on on the property as far as food and entertainment, even though it seemed to be a lot going on. We loved the atmosphere, The view will definitely stay again. There wasn’t any parking on the parking ...

Reviewed on Mar 13, 2026

Opens in a new windowBest Western Plus Island Palms Hotel & Marina
Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
$226 nightly
The price is $260 total per night from Apr 5 to Apr 6
$260 total
Apr 5 - Apr 6
Total with taxes and fees
2 outdoor tennis courts, an outdoor pool, and a hot tub are all featured at this smoke-free resort. Spend a day at the beach surfing, or relax with free beach ...
8.6/10 Excellent! (1,909 reviews)
Pull out couch mattress was in bad shape. Screen door wouldnt open very well to the patio. Bed was amazing. Kitchenette was good. Restaurants were amazing.

Reviewed on Mar 14, 2026

Opens in a new windowBahia Resort Hotel
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