Find and compare 3 Star hotels in Otay Mesa
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Top Otay Mesa 3 Star hotels

Bay Club Hotel & Marina
2131 Shelter Island Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $178 total per night from Oct 6 to Oct 7
$178 total
Oct 6 - Oct 7
Total with taxes and fees
A marina, a gym, and a restaurant are all featured at this traditional hotel. Traveling on business? Take advantage of the free WiFi in public areas and free ...
9/10 Wonderful! (2,972 reviews)
"Close to all I wanted to go , wish we had gotten a better view since I said it was our honeymoon but it was what it was."
Reviewed on Oct 1, 2025

The DEXTRO Little Italy, BW Premier Collection
1617 1st Avenue, San Diego, CA
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $138 total per night from Oct 8 to Oct 9
$138 total
Oct 8 - Oct 9
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
8.6/10 Excellent! (474 reviews)
"Clean room"
Reviewed on Sep 27, 2025

Handlery Hotel
950 Hotel Cir N, San Diego, CA
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $126 total per night from Oct 5 to Oct 6
$126 total
Oct 5 - Oct 6
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
8/10 Very Good! (2,132 reviews)
"Very nice"
Reviewed on Oct 1, 2025

Best Western Plus Marina Gateway Hotel
800 Bay Marina Dr, National City, CA
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $153 total per night from Oct 5 to Oct 6
$153 total
Oct 5 - Oct 6
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this eco-certified hotel. Bring the family and enjoy the mini golf, children's pool, and kid-friendly ...
9.2/10 Wonderful! (3,291 reviews)
"Thanks"
Reviewed on Oct 1, 2025

Days Inn by Wyndham San Diego Hotel Circle
543 Hotel Circle S, San Diego, CA
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $113 total per night from Oct 5 to Oct 6
$113 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...
7.8/10 Good! (2,370 reviews)
"Fast check in"
Reviewed on Sep 30, 2025

The Dana on Mission Bay
1710 W Mission Bay Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
$153 nightly
The price is $175 total per night from Oct 26 to Oct 27
$175 total
Oct 26 - Oct 27
Total with taxes and fees
A marina, 2 outdoor pools, and 2 hot tubs are all featured at this smoke-free hotel. If you want to take your pet along, this pet-friendly property offers everything ...
8.8/10 Excellent! (3,793 reviews)
"The hotel was clean, the room was nice. The only issue was with the location of the AC, but it was not that big of an issue for us, besides when getting ready in the bathroom and getting blasted with cold air."
Reviewed on Oct 1, 2025

Wyndham Garden San Diego Near SeaWorld
3737 Sports Arena Blvd, San Diego, CA
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $108 total per night from Oct 8 to Oct 9
$108 total
Oct 8 - Oct 9
Total with taxes and fees
An outdoor pool, self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Traveling on business? Take advantage of the ...
7.2/10 Good! (4,060 reviews)
"the hotel was very clean and the front desk was very friendly"
Reviewed on Sep 30, 2025

The Sofia Hotel
150 W Broadway, San Diego, CA
Fully refundableReserve now, pay when you stay
$154 nightly
The price is $178 total per night from Nov 2 to Nov 3
$178 total
Nov 2 - Nov 3
Total with taxes and fees
A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
8.2/10 Very Good! (1,597 reviews)
"The staff are wonderful: friendly, helpful"
Reviewed on Sep 26, 2025

Comfort Inn Sea World Area
3880 Greenwood St, San Diego, CA
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $107 total per night from Oct 13 to Oct 14
$107 total
Oct 13 - Oct 14
Total with taxes and fees
A gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like buffet breakfast and WiFi in public areas. ...
8.4/10 Very Good! (2,808 reviews)
"Nice interior and rooms."
Reviewed on Sep 29, 2025

Best Western Seven Seas
411 Hotel Circle South, San Diego, CA
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $97 total per night from Oct 5 to Oct 6
$97 total
Oct 5 - Oct 6
Total with taxes and fees
2 hot tubs, an outdoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi ...
7.8/10 Good! (2,976 reviews)
"N/A"
Reviewed on Sep 27, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Otay Mesa hotel reviews by fellow wanderers

The Dana on Mission Bay
5 out of 5
Posted 15 hours ago
Travelocity Verified Review
"The hotel was clean, the room was nice. The only issue was with the location of the AC, but it was not that big of an issue for us, besides when getting ready in the bathroom and getting blasted with cold air. "
A verified traveler stayed at The Dana on Mission Bay
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