Explore top 2026 4 Star Hotels in Otay Mesa West

Name: Omni San Diego Hotel at the Ballpark
Price range: $271 total
Rating: 9.2

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Top Otay Mesa West 4 Star hotels

Hard Rock Hotel San Diego

207 5th Ave San Diego CA

Fully refundableReserve now, pay when you stay

$237 nightly

$274 total

Apr 5 - Apr 6

Total with taxes and fees

A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free ...

9/10 Wonderful! (3,419 reviews)

Pool seating was less than expected during a holiday weekend. Only water fountain refill station was in the gym.

Reviewed on Mar 15, 2026

Manchester Grand Hyatt San Diego

1 Market Pl San Diego CA

Fully refundableReserve now, pay when you stay

$236 nightly

$274 total

Apr 2 - Apr 3

Total with taxes and fees

This hotel features 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

9/10 Wonderful! (2,900 reviews)

Perfect service

Reviewed on Mar 13, 2026

Paradise Point Resort & Spa

1404 Vacation Rd San Diego CA

Fully refundableReserve now, pay when you stay

$273 nightly

$314 total

Apr 5 - Apr 6

Total with taxes and fees

This smoke-free resort features a full-service spa, a marina, and 2 restaurants. Family-friendly amenities include mini golf and kid-friendly dining, along with ...

8.6/10 Excellent! (2,454 reviews)

Dog track of a hotel. Not sure how this is rated 4 stars. Old run down rooms that smell like mildew, things falling apart, rust, and damaged.

Reviewed on Mar 15, 2026

Hyatt Regency Mission Bay Spa and Marina

1441 Quivira Rd San Diego CA

Fully refundableReserve now, pay when you stay

$216 nightly

$248 total

Apr 5 - Apr 6

Total with taxes and fees

This smoke-free hotel features a full-service spa, a marina, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public ...

8.4/10 Very Good! (1,607 reviews)

The view was fantastic. Room had black mold above the bathroom light that had been broken and not fixed before our stay. Staff offered upgrade for our honeymoon then mentioned it was an upcharge. The ice machine outside our room was broken and I could hear it malfunctioning all night. There was a ...

Reviewed on Mar 15, 2026

Wyndham San Diego Bayside

1355 N Harbor Drive San Diego CA

Fully refundableReserve now, pay when you stay

$182 nightly

$211 total

Mar 19 - Mar 20

Total with taxes and fees

This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

8.4/10 Very Good! (6,056 reviews)

Excellent hotel right next to cruise ship pier. Couldn't have had a better experience. Staff was very helpful and friendly.

Reviewed on Mar 15, 2026

San Diego Marriott Gaslamp Quarter

660 K St San Diego CA

Fully refundableReserve now, pay when you stay

$161 nightly

$186 total

Apr 2 - Apr 3

Total with taxes and fees

A nightclub, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, express ...

8.8/10 Excellent! (1,670 reviews)

The staff was fantastic. Definitely the highlight of the stay. The rooms are very old in need of significant upgrades and the king suite isn't worth staying in. The jr king suite is much better.

Reviewed on Mar 15, 2026

Lafayette Hotel & Club

2223 El Cajon Blvd San Diego CA

Fully refundableReserve now, pay when you stay

$249 nightly

$286 total

Mar 19 - Mar 20

Total with taxes and fees

This smoke-free hotel features 2 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...

9.2/10 Wonderful! (1,526 reviews)

Hell yeah

Reviewed on Mar 15, 2026

Sheraton San Diego Resort

1380 Harbor Island Dr San Diego CA

Fully refundableReserve now, pay when you stay

$163 nightly

$188 total

Apr 1 - Apr 2

Total with taxes and fees

A marina, 5 restaurants, and 3 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi ...

8.4/10 Very Good! (3,378 reviews)

Excelent

Reviewed on Mar 15, 2026

Omni San Diego Hotel at the Ballpark

675 L St San Diego CA

Fully refundableReserve now, pay when you stay

$234 nightly

$271 total

Apr 3 - Apr 4

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

9.2/10 Wonderful! (2,082 reviews)

Really enjoyed our stay there 😍

Reviewed on Mar 15, 2026

San Diego Mission Bay Resort

1775 E Mission Bay Dr San Diego CA

Fully refundableReserve now, pay when you stay

$285 nightly

$328 total

Apr 5 - Apr 6

Total with taxes and fees

A full-service spa, 2 restaurants, and 5 outdoor tennis courts are all featured at this Mediterranean resort. There's fun for all ages with a children's pool ...

8.4/10 Very Good! (1,373 reviews)

Will definitely come back

Reviewed on Mar 15, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.