Explore top 2025 4 Star Hotels in Key West

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Top Key West 4 Star hotels

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street, Key West, FL
Fully refundable
The price is $272 total per night from Nov 30 to Dec 1
$272 total
per night
Nov 30 - Dec 1
This hotel features a full-service spa, 3 outdoor pools, and a restaurant. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Traveling ...
8.6/10 Excellent! (2,828 reviews)
All aspects were fabulous

Reviewed on Oct 28, 2025

Opens in a new windowSouthernmost Beach Resort and Guesthouses
Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa

4 out of 5
601 Front St, Key West, FL
Fully refundableReserve now, pay when you stay
The price is $361 total per night from Nov 20 to Nov 21
$361 total
per night
Nov 20 - Nov 21
This smoke-free resort features a full-service spa, a marina, and a restaurant. Enjoy the outdoor pool and perks like free WiFi. Enjoy the 24-hour gym and unwind ...
8.8/10 Excellent! (1,015 reviews)
The hotel is right on the beach, had all the amenities and walking distance from Duvall street and Mallory square. Sunsets were beautiful

Reviewed on Oct 25, 2025

Opens in a new windowHyatt Centric Key West Resort and Spa
Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

4 out of 5
5950 Peninsular Avenue, Key West, FL
Fully refundableReserve now, pay when you stay
The price is $232 total per night from Nov 16 to Nov 17
$232 total
per night
Nov 16 - Nov 17
A marina, 6 outdoor pools, and a 24-hour gym are all featured at this smoke-free hotel. Business travelers can take advantage of the free WiFi in public areas. ...
8.8/10 Excellent! (1,730 reviews)
This was my 4th year in a row staying at this property. Great views and a great location.

Reviewed on Oct 28, 2025

Opens in a new windowOceans Edge Key West Resort, Hotel & Marina
Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Boulevard, Key West, FL
Fully refundableReserve now, pay when you stay
The price is $264 total per night from Nov 18 to Nov 19
$264 total
per night
Nov 18 - Nov 19
This hotel features a restaurant, an outdoor pool, and a bar/lounge. If you want to take your pet along, this pet-friendly property offers everything you'll ...
8.6/10 Excellent! (1,776 reviews)
Only problem was elevator was not working the entire week we were there. Room was clean pool was great. Service was great beach access was directly across the street.

Reviewed on Oct 24, 2025

Opens in a new windowMargaritaville Beach House Key West
La Concha Key West, Autograph Collection

La Concha Key West, Autograph Collection

4 out of 5
430 Duval St, Key West, FL
Fully refundableReserve now, pay when you stay
The price is $262 total per night from Nov 17 to Nov 18
$262 total
per night
Nov 17 - Nov 18
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express ...
9/10 Wonderful! (242 reviews)
We loved the location

Reviewed on Oct 27, 2025

Opens in a new windowLa Concha Key West, Autograph Collection
DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd, Key West, FL
Fully refundableReserve now, pay when you stay
The price is $202 total per night from Nov 3 to Nov 4
$202 total
per night
Nov 3 - Nov 4
This resort features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8/10 Very Good! (1,010 reviews)
Some staff are rude but other wise it was a good stay

Reviewed on Oct 27, 2025

Opens in a new windowDoubleTree Resort by Hilton Grand Key - Key West
The Perry Hotel & Marina Key West

The Perry Hotel & Marina Key West

4 out of 5
7001 Shrimp Road, Key West, FL
Fully refundableReserve now, pay when you stay
The price is $212 total per night from Nov 12 to Nov 13
$212 total
per night
Nov 12 - Nov 13
A marina, 2 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Traveling for business? Take advantage of the free WiFi in public areas, ...
9.4/10 Exceptional! (1,132 reviews)
Amazing property and staff. Marina on-site is extremely convenient for water sports activities. We'll be back!!!

Reviewed on Oct 26, 2025

Opens in a new windowThe Perry Hotel & Marina Key West
Parrot Key Hotel & Villas

Parrot Key Hotel & Villas

4 out of 5
2801 N Roosevelt Blvd, Key West, FL
Fully refundableReserve now, pay when you stay
The price is $218 total per night from Nov 16 to Nov 17
$218 total
per night
Nov 16 - Nov 17
This smoke-free hotel features 4 outdoor pools, a gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9/10 Wonderful! (1,136 reviews)
The property was great.

Reviewed on Oct 27, 2025

Opens in a new windowParrot Key Hotel & Villas
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard, Key West, FL
Fully refundableReserve now, pay when you stay
The price is $157 total per night from Dec 1 to Dec 2
$157 total
per night
Dec 1 - Dec 2
This hotel features 2 restaurants, 2 outdoor pools, and a 24-hour gym. There's fun for all ages with mini golf and an arcade/game room, and families will appreciate ...
7.8/10 Good! (1,636 reviews)
Nice Hotel

Reviewed on Oct 26, 2025

Opens in a new windowBlue Flamingo Resort Key West
Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton

4 out of 5
1500 Reynolds Street, Key West, FL
Fully refundableReserve now, pay when you stay
The price is $363 total per night from Dec 1 to Dec 2
$363 total
per night
Dec 1 - Dec 2
A private beach, a full-service spa, and 2 outdoor pools are all featured at this smoke-free resort. Relax with sun loungers and beach umbrellas, and cool off ...
8.2/10 Very Good! (409 reviews)
Yes property is in an excellent location and the rooms and common areas were very good.

Reviewed on Oct 22, 2025

Opens in a new windowCasa Marina Key West, Curio Collection by Hilton
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4 Star Hotels Key West

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Key West 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Key West will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Key West, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Key West hotel reviews by fellow wanderers

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