Explore 64 Luxury Hotels in Key West

Name: Fairfield by Marriott Inn & Suites Key West at The Keys Collection
Price range: $179 total
Rating: 8.6

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Best Luxury Hotels in Key West

H2O Suites - Adults Only

1212 Simonton Street Key West FL

$389 nightly

$438 total

Jul 8 - Jul 9

Total with taxes and fees

This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Business travelers can take advantage of the laundry service. There's a gym on site, and ...

9.8/10 Exceptional! (623 reviews)

"I’ll stay factual Small parking garage. We never took our car for fear we’d have to park on the street No bell cap or luggage assistance despite what the front door receptionist stated Shower needed to be repaired as no cold or cool water was possible. It was repaired. Didn’t anyone notice before ..."

Reviewed on Jul 2, 2026

Southernmost House - Adult Exclusive

1400 Duval Street Key West FL

$272 nightly

$306 total

Jul 26 - Jul 27

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Guests will appreciate free perks like cooked-to-order breakfast and WiFi in public areas. ...

9.4/10 Exceptional! (1,002 reviews)

"The staff were extremely welcoming, and the property had a wonderful view and nice cool air conditioning. The shower was massive and really nice. Recommended!"

Reviewed on Jul 3, 2026

The Marker Key West Harbor Resort

200 William Street Key West FL

Fully refundable

$230 nightly

$259 total

Jul 14 - Jul 15

Total with taxes and fees

This smoke-free hotel features 3 outdoor pools, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...

9.2/10 Wonderful! (1,005 reviews)

"The front dest agent was very nice. Check in was a breeze. The hotel is very clean, modern and has multiple pools to enjoy. It is also very close to everything. We parked and walked most of key west."

Reviewed on Jul 6, 2026

Oceans Edge Key West Resort, Hotel & Marina

5950 Peninsular Avenue Key West FL

Fully refundableReserve now, pay when you stay

$245 nightly

$276 total

Jul 13 - Jul 14

Total with taxes and fees

A marina, 6 outdoor pools, and a 24-hour gym are all featured at this smoke-free hotel. Business travelers can take advantage of the free WiFi in public areas. ...

9/10 Wonderful! (1,859 reviews)

"It was a good experience. Thank you!"

Reviewed on Jul 5, 2026

Southernmost Beach Resort and Guesthouses

1319 Duval Street Key West FL

Fully refundableReserve now, pay when you stay

$232 nightly

$261 total

Jul 14 - Jul 15

Total with taxes and fees

This hotel features a full-service spa, 3 outdoor pools, and a restaurant. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Traveling ...

8.8/10 Excellent! (3,426 reviews)

"Management was horrible! Wayyyy over priced and wayyy under delivered. Dirty rooms, ants, cracks in the door, false advertisement! Horrible rotten egg smell all over. Couldn’t use the beach! Don’t stay here!!! Complete rip off and they only wanted to reimburse about less than 10% for a $$$$ stay!!! ..."

Reviewed on Jul 5, 2026

Casa Marina Key West, Curio Collection by Hilton

1500 Reynolds Street Key West FL

Fully refundableReserve now, pay when you stay

$252 nightly

$283 total

Jul 16 - Jul 17

Total with taxes and fees

A private beach, a full-service spa, and 2 outdoor pools are all featured at this smoke-free resort. Relax with sun loungers and beach umbrellas, and cool off ...

8.6/10 Excellent! (739 reviews)

"Rooms & amenities were great, but definitely not a beach place to stay."

Reviewed on Jul 5, 2026

Fairfield by Marriott Inn & Suites Key West at The Keys Collection

3852 North Roosevelt Boulevard Key West FL

Fully refundableReserve now, pay when you stay

$159 nightly

$179 total

Jul 13 - Jul 14

Total with taxes and fees

This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...

8.6/10 Excellent! (1,045 reviews)

"Room cleaning - OK Staff - OK Breakfast-OK not more Air Con - great"

Reviewed on Jul 5, 2026

Seashell Motel

718 South Street Key West FL

Fully refundableReserve now, pay when you stay

$131 nightly

$147 total

Jul 8 - Jul 9

Total with taxes and fees

This hostel doesn't skimp on freebies - guests receive free WiFi and free self parking. A picnic area, luggage storage, and concierge services are also on ...

8/10 Very Good! (1,001 reviews)

"Excelente servicio de las personas de front desk para hacer check in. Las habitaciones muy limpias no tuve ningún problema con la habitación la persona que se encargo de ir a cambiar las toallas y las sábanas excelente servicio. Volveré en unos meses lo recomiendo."

Reviewed on Jul 6, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Key West

Opal Key Resort & Marina, Key West

245 Front Street Key West FL

$294 nightly

$331 total

Jul 7 - Jul 8

Total with taxes and fees

9.2/10 Wonderful! (1,155 reviews)

Key West Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Key West luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Key West to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Key West will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Key West, and plan your next opulent escape.

Key West hotels essential information

Accommodation	2,666 hotels
Lowest Price	$147
Highest Price	$517
Popular hotels	Oceans Edge Key West Resort, Hotel & Marina, The Marker Key West Harbor Resort, Casa Marina Key West, Curio Collection by Hilton, Southernmost Beach Resort and Guesthouses, H2O Suites - Adults Only, Seashell Motel, Southernmost House - Adult Exclusive, Fairfield by Marriott Inn & Suites Key West at The Keys Collection