Explore 64 Luxury Hotels in Key West

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Best Luxury Hotels in Key West

H2O Suites - Adults Only

H2O Suites - Adults Only

1212 Simonton Street Key West FL
$367 nightly
The price is $413 total per night from Dec 1 to Dec 2
$413 total
Dec 1 - Dec 2
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Business travelers can take advantage of the laundry service. There's a gym on site, and ...
9.8/10 Exceptional! (578 reviews)
Every thing was awsome clean room great people great room

Reviewed on Nov 18, 2025

Opens in a new windowH2O Suites - Adults Only
Southernmost House

Southernmost House

1400 Duval Street Key West FL
$322 nightly
The price is $362 total per night from Dec 15 to Dec 16
$362 total
Dec 15 - Dec 16
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Unwind with a drink at the poolside bar and enjoy perks like free continental breakfast ...
9.2/10 Wonderful! (1,003 reviews)
Hospitality and location

Reviewed on Nov 20, 2025

Opens in a new windowSouthernmost House
The Marker Key West Harbor Resort

The Marker Key West Harbor Resort

200 William Street Key West FL
Fully refundableReserve now, pay when you stay
$263 nightly
The price is $296 total per night from Dec 2 to Dec 3
$296 total
Dec 2 - Dec 3
Total with taxes and fees
This smoke-free hotel features 3 outdoor pools, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
9/10 Wonderful! (1,009 reviews)
The staff was fabulous!

Reviewed on Nov 21, 2025

Opens in a new windowThe Marker Key West Harbor Resort
Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

5950 Peninsular Avenue Key West FL
Fully refundableReserve now, pay when you stay
$202 nightly
The price is $227 total per night from Dec 1 to Dec 2
$227 total
Dec 1 - Dec 2
Total with taxes and fees
A marina, 6 outdoor pools, and a 24-hour gym are all featured at this smoke-free hotel. Business travelers can take advantage of the free WiFi in public areas. ...
8.8/10 Excellent! (1,744 reviews)
Everything was great!

Reviewed on Nov 20, 2025

Opens in a new windowOceans Edge Key West Resort, Hotel & Marina
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

1319 Duval Street Key West FL
Fully refundableReserve now, pay when you stay
$240 nightly
The price is $270 total per night from Dec 17 to Dec 18
$270 total
Dec 17 - Dec 18
Total with taxes and fees
This hotel features a full-service spa, 3 outdoor pools, and a restaurant. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Traveling ...
8.6/10 Excellent! (2,872 reviews)
Everyone was very helpful but our air conditioner was extremely loud and leaking, our shower was not draining. I contacted the front desk and they said they sent someone but unfortunately it never got better.

Reviewed on Nov 23, 2025

Opens in a new windowSouthernmost Beach Resort and Guesthouses
Fairfield Inn & Suites by Marriott Key West at the Keys Collection

Fairfield Inn & Suites by Marriott Key West at the Keys Collection

3852 North Roosevelt Boulevard Key West FL
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $151 total per night from Dec 7 to Dec 8
$151 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
8.4/10 Very Good! (1,001 reviews)
Good 👍

Reviewed on Nov 17, 2025

Opens in a new windowFairfield Inn & Suites by Marriott Key West at the Keys Collection
Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton

1500 Reynolds Street Key West FL
Fully refundableReserve now, pay when you stay
$299 nightly
The price is $336 total per night from Dec 17 to Dec 18
$336 total
Dec 17 - Dec 18
Total with taxes and fees
A private beach, a full-service spa, and 2 outdoor pools are all featured at this smoke-free resort. Relax with sun loungers and beach umbrellas, and cool off ...
8.2/10 Very Good! (443 reviews)
The hotel is in good state, clean and fresh; the rooms offer plenty of comfort and beach front balcony is a pleasing extra!

Reviewed on Nov 23, 2025

Opens in a new windowCasa Marina Key West, Curio Collection by Hilton
Seashell Motel

Seashell Motel

718 South Street Key West FL
Fully refundableReserve now, pay when you stay
$142 nightly
The price is $160 total per night from Nov 30 to Dec 1
$160 total
Nov 30 - Dec 1
Total with taxes and fees
This hostel doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, a picnic area, and luggage storage are also on offer.
7.8/10 Good! (1,002 reviews)
Yes

Reviewed on Nov 14, 2025

Opens in a new windowSeashell Motel
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More 4 star hotels in Key West

Key West Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Key West luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Key West to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Key West will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Key West, and plan your next opulent escape.


Key West hotels essential information

Accommodation
2,730 hotels
Lowest Price
$151
Highest Price
$458
Popular hotels
Oceans Edge Key West Resort, Hotel & Marina, The Marker Key West Harbor Resort, Casa Marina Key West, Curio Collection by Hilton, Southernmost Beach Resort and Guesthouses, H2O Suites - Adults Only, Seashell Motel, Southernmost House, Fairfield Inn & Suites by Marriott Key West at the Keys Collection

Popular Luxury Stays in Key West

Recent Key West Hotel Reviews By Fellow Wanderers

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