Explore 64 Luxury Hotels in Key West

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Best Luxury Hotels in Key West

H2O Suites - Adults Only

H2O Suites - Adults Only

1212 Simonton Street, Key West, FL
$339 nightly
The price is $381 total per night from Aug 3 to Aug 4
$381 total
Aug 3 - Aug 4
Total includes taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Business travelers can take advantage of the laundry service. There's a gym on site, and ...
9.8/10 Exceptional! (541 reviews)
"The star was very accommodating."

Reviewed on Jun 25, 2025

H2O Suites - Adults Only
Southernmost House

Southernmost House

1400 Duval Street, Key West, FL
$269 nightly
The price is $303 total per night from Jul 9 to Jul 10
$303 total
Jul 9 - Jul 10
Total includes taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Unwind with a drink at the poolside bar and enjoy perks like free continental breakfast ...
9.2/10 Wonderful! (1,001 reviews)
"Beautiful property-very clean,gorgeous views and easy walkability!"

Reviewed on Jul 2, 2025

Southernmost House
The Marker Key West Harbor Resort

The Marker Key West Harbor Resort

200 William Street, Key West, FL
Fully refundableReserve now, pay when you stay
$278 nightly
The price is $313 total per night from Jul 22 to Jul 23
$313 total
Jul 22 - Jul 23
Total includes taxes and fees
This eco-certified hotel features 3 outdoor pools, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
9/10 Wonderful! (1,002 reviews)
"Resort was located"

Reviewed on Jul 4, 2025

The Marker Key West Harbor Resort
Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

5950 Peninsular Avenue, Key West, FL
Fully refundableReserve now, pay when you stay
$241 nightly
The price is $271 total per night from Aug 3 to Aug 4
$271 total
Aug 3 - Aug 4
Total includes taxes and fees
A marina, 6 outdoor pools, and a 24-hour gym are all featured at this smoke-free hotel. Business travelers can take advantage of the free WiFi in public areas. ...
8.8/10 Excellent! (1,668 reviews)
"Stunning! Great view and amenities."

Reviewed on Jul 3, 2025

Oceans Edge Key West Resort, Hotel & Marina
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

1319 Duval Street, Key West, FL
Fully refundable
$259 nightly
The price is $291 total per night from Aug 4 to Aug 5
$291 total
Aug 4 - Aug 5
Total includes taxes and fees
This hotel features a full-service spa, 3 outdoor pools, and a restaurant. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Traveling ...
8.6/10 Excellent! (2,588 reviews)
"My girlfriend and I had a nice stay. It’s a decent place. The pool gets extremely crowded and there is not much seating options out by the pool area. Beds are not the most comfortable. Bar out by the pool was a great amenity. Lounge pool is nice for adults only who are looking to relax. Everything ..."

Reviewed on Jul 5, 2025

Southernmost Beach Resort and Guesthouses
Fairfield Inn & Suites by Marriott Key West at the Keys Collection

Fairfield Inn & Suites by Marriott Key West at the Keys Collection

3852 North Roosevelt Boulevard, Key West, FL
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $171 total per night from Jul 20 to Jul 21
$171 total
Jul 20 - Jul 21
Total includes taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
8.4/10 Very Good! (1,003 reviews)
"beautifull hotel"

Reviewed on Jul 2, 2025

Fairfield Inn & Suites by Marriott Key West at the Keys Collection
Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton

1500 Reynolds Street, Key West, FL
Fully refundableReserve now, pay when you stay
$291 nightly
The price is $328 total per night from Aug 4 to Aug 5
$328 total
Aug 4 - Aug 5
Total includes taxes and fees
A private beach, a full-service spa, and 2 outdoor pools are all featured at this smoke-free resort. Relax with sun loungers and beach umbrellas, and cool off ...
8.2/10 Very Good! (212 reviews)
"Lovely hotel, rooms clean and spacious, staff very friendly. We would stay again."

Reviewed on Jul 4, 2025

Casa Marina Key West, Curio Collection by Hilton
Seashell Motel & Key West Hostel

Seashell Motel & Key West Hostel

718 South Street, Key West, FL
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $135 total per night from Jul 6 to Jul 7
$135 total
Jul 6 - Jul 7
Total includes taxes and fees
This hostel doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, a picnic area, and luggage storage are also on offer.
7.6/10 Good! (1,003 reviews)
"Great choice"

Reviewed on Jun 23, 2025

Seashell Motel & Key West Hostel
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More 4 star hotels in Key West

Key West Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Key West luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Key West to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Key West will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Key West, and plan your next opulent escape.


Key West hotels essential information

Accommodation
2,745 hotels
Lowest Price
$135
Highest Price
$381
Popular hotels
Oceans Edge Key West Resort, Hotel & Marina, The Marker Key West Harbor Resort, Casa Marina Key West, Curio Collection by Hilton, Southernmost Beach Resort and Guesthouses, H2O Suites - Adults Only, Seashell Motel & Key West Hostel, Southernmost House, Fairfield Inn & Suites by Marriott Key West at the Keys Collection

Popular Luxury Stays in Key West

Recent Key West Hotel Reviews By Fellow Wanderers

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