Explore 64 Luxury Hotels in Key West

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Best Luxury Hotels in Key West

H2O Suites - Adults Only

H2O Suites - Adults Only

1212 Simonton Street Key West FL
$486 nightly
The price is $547 total per night from May 26 to May 27
$547 total
May 26 - May 27
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Business travelers can take advantage of the laundry service. There's a gym on site, and ...
9.8/10 Exceptional! (599 reviews)
This resort was in the perfect location for exploring Key West. Highly recommend!

Reviewed on Apr 23, 2026

Opens in a new windowH2O Suites - Adults Only
Southernmost House - Adult Exclusive

Southernmost House - Adult Exclusive

1400 Duval Street Key West FL
$412 nightly
The price is $463 total per night from Apr 30 to May 1
$463 total
Apr 30 - May 1
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Guests will appreciate free perks like continental breakfast and WiFi in public areas. Self ...
9.4/10 Exceptional! (1,005 reviews)
Amazing

Reviewed on Apr 24, 2026

Opens in a new windowSouthernmost House - Adult Exclusive
The Marker Key West Harbor Resort

The Marker Key West Harbor Resort

200 William Street Key West FL
Fully refundable
$307 nightly
The price is $346 total per night from Apr 28 to Apr 29
$346 total
Apr 28 - Apr 29
Total with taxes and fees
This smoke-free hotel features 3 outdoor pools, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
9.2/10 Wonderful! (1,002 reviews)
Fourth time in Key West…first time at The Marker. Absolutely loved our stay. Fun atmosphere, great staff - especially at the bar - and well appointed rooms with comfortable beds. All in a great location with gorgeous views. Will definitely be back.

Reviewed on Apr 26, 2026

Opens in a new windowThe Marker Key West Harbor Resort
Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

5950 Peninsular Avenue Key West FL
Fully refundableReserve now, pay when you stay
$262 nightly
The price is $294 total per night from May 18 to May 19
$294 total
May 18 - May 19
Total with taxes and fees
A marina, 6 outdoor pools, and a 24-hour gym are all featured at this smoke-free hotel. Business travelers can take advantage of the free WiFi in public areas. ...
9/10 Wonderful! (1,858 reviews)
Great super clean resort. Room was beautiful. Not on the main Key West strip, but hourly shuttle that drops you off right there. Only issue was the lack of water pressure. Resort is becoming a Hilton property in a few months.

Reviewed on Apr 26, 2026

Opens in a new windowOceans Edge Key West Resort, Hotel & Marina
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

1319 Duval Street Key West FL
Fully refundableReserve now, pay when you stay
$330 nightly
The price is $372 total per night from May 19 to May 20
$372 total
May 19 - May 20
Total with taxes and fees
This hotel features a full-service spa, 3 outdoor pools, and a restaurant. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Traveling ...
8.8/10 Excellent! (3,241 reviews)
Love it here. Everything you could want. A little pricey , but you get what you pay for.

Reviewed on Apr 27, 2026

Opens in a new windowSouthernmost Beach Resort and Guesthouses
Fairfield by Marriott Inn & Suites Key West at The Keys Collection

Fairfield by Marriott Inn & Suites Key West at The Keys Collection

3852 North Roosevelt Boulevard Key West FL
Fully refundableReserve now, pay when you stay
$222 nightly
The price is $250 total per night from May 10 to May 11
$250 total
May 10 - May 11
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
8.6/10 Excellent! (1,006 reviews)
Breakfast was awesome and the pool area

Reviewed on Apr 24, 2026

Opens in a new windowFairfield by Marriott Inn & Suites Key West at The Keys Collection
Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton

1500 Reynolds Street Key West FL
Fully refundableReserve now, pay when you stay
$371 nightly
The price is $418 total per night from May 7 to May 8
$418 total
May 7 - May 8
Total with taxes and fees
A private beach, a full-service spa, and 2 outdoor pools are all featured at this smoke-free resort. Relax with sun loungers and beach umbrellas, and cool off ...
8.4/10 Very Good! (630 reviews)
Wonderful!

Reviewed on Apr 26, 2026

Opens in a new windowCasa Marina Key West, Curio Collection by Hilton
Seashell Motel

Seashell Motel

718 South Street Key West FL
Fully refundableReserve now, pay when you stay
$186 nightly
The price is $209 total per night from Apr 28 to Apr 29
$209 total
Apr 28 - Apr 29
Total with taxes and fees
This hostel doesn't skimp on freebies - guests receive free WiFi and free self parking. A picnic area, luggage storage, and concierge services are also on ...
8/10 Very Good! (1,004 reviews)
I booked this hotel as a budget for one night. We got there early thinking we would relax by the pool in the cute little courtyard. No pool no courtyard. Not even a place to sit outside. No chairs in the room. Way to loud. Have to say the staff was nice. I would have gladly paid more for a pool or ...

Reviewed on Apr 26, 2026

Opens in a new windowSeashell Motel
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More 4 star hotels in Key West

Key West Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Key West luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Key West to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Key West will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Key West, and plan your next opulent escape.


Key West hotels essential information

Accommodation
2,675 hotels
Lowest Price
$209
Highest Price
$547
Popular hotels
Oceans Edge Key West Resort, Hotel & Marina, The Marker Key West Harbor Resort, Casa Marina Key West, Curio Collection by Hilton, Southernmost Beach Resort and Guesthouses, H2O Suites - Adults Only, Seashell Motel, Southernmost House - Adult Exclusive, Fairfield by Marriott Inn & Suites Key West at The Keys Collection

Popular Luxury Stays in Key West

Recent Key West Hotel Reviews By Fellow Wanderers

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