Explore 64 Luxury Hotels in Key West

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Best Luxury Hotels in Key West

H2O Suites - Adults Only

H2O Suites - Adults Only

1212 Simonton Street Key West FL
$839 nightly
The price is $944 total per night from Feb 10 to Feb 11
$944 total
Feb 10 - Feb 11
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Business travelers can take advantage of the laundry service. There's a gym on site, and ...
9.8/10 Exceptional! (585 reviews)
Location is excellent. Staff is outstanding. Love rooftop pool.

Reviewed on Jan 28, 2026

Opens in a new windowH2O Suites - Adults Only
Southernmost House

Southernmost House

1400 Duval Street Key West FL
$562 nightly
The price is $632 total per night from Mar 1 to Mar 2
$632 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Guests will appreciate free perks like continental breakfast and WiFi in public areas. Self ...
9.4/10 Exceptional! (999 reviews)
Courteous staff, great breakfast and wonderful ocean front location! We were able to go everywhere we wanted on foot.

Reviewed on Feb 4, 2026

Opens in a new windowSouthernmost House
The Marker Key West Harbor Resort

The Marker Key West Harbor Resort

200 William Street Key West FL
$611 nightly
The price is $688 total per night from Mar 3 to Mar 4
$688 total
Mar 3 - Mar 4
Total with taxes and fees
This smoke-free hotel features 3 outdoor pools, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
9/10 Wonderful! (1,002 reviews)
Breakfast was better than expected, heated pools, polite staff, and clean property.

Reviewed on Feb 8, 2026

Opens in a new windowThe Marker Key West Harbor Resort
Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

5950 Peninsular Avenue Key West FL
Fully refundableReserve now, pay when you stay
$403 nightly
The price is $453 total per night from Mar 12 to Mar 13
$453 total
Mar 12 - Mar 13
Total with taxes and fees
A marina, 6 outdoor pools, and a 24-hour gym are all featured at this smoke-free hotel. Business travelers can take advantage of the free WiFi in public areas. ...
8.8/10 Excellent! (1,801 reviews)
Amazing

Reviewed on Feb 8, 2026

Opens in a new windowOceans Edge Key West Resort, Hotel & Marina
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

1319 Duval Street Key West FL
$549 nightly
The price is $617 total per night from Feb 10 to Feb 11
$617 total
Feb 10 - Feb 11
Total with taxes and fees
This hotel features a full-service spa, 3 outdoor pools, and a restaurant. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Traveling ...
8.6/10 Excellent! (3,066 reviews)
Clean room, friendly staff, good food, good accommodations

Reviewed on Feb 9, 2026

Opens in a new windowSouthernmost Beach Resort and Guesthouses
Fairfield Inn & Suites by Marriott Key West at the Keys Collection

Fairfield Inn & Suites by Marriott Key West at the Keys Collection

3852 North Roosevelt Boulevard Key West FL
$420 nightly
The price is $473 total per night from Mar 2 to Mar 3
$473 total
Mar 2 - Mar 3
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
8.4/10 Very Good! (1,002 reviews)
Room, Staff, Pool, Parking - everything worth the money spent. They gave us beach chairs & towels. Free drinks. Breakfast had lot of options. Checkout was very quick thanks to the staff.

Reviewed on Jan 30, 2026

Opens in a new windowFairfield Inn & Suites by Marriott Key West at the Keys Collection
Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton

1500 Reynolds Street Key West FL
$534 nightly
The price is $601 total per night from Feb 10 to Feb 11
$601 total
Feb 10 - Feb 11
Total with taxes and fees
A private beach, a full-service spa, and 2 outdoor pools are all featured at this smoke-free resort. Relax with sun loungers and beach umbrellas, and cool off ...
8.2/10 Very Good! (533 reviews)
Great atmosphere. Perfect location. Beautiful beach area.

Reviewed on Feb 8, 2026

Opens in a new windowCasa Marina Key West, Curio Collection by Hilton
Seashell Motel

Seashell Motel

718 South Street Key West FL
Fully refundableReserve now, pay when you stay
$252 nightly
The price is $284 total per night from Feb 10 to Feb 11
$284 total
Feb 10 - Feb 11
Total with taxes and fees
This hostel doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, a picnic area, and luggage storage are also on offer.
7.8/10 Good! (1,004 reviews)
The room was beautifully done, clean and welcoming. The shower was fabulous! We were in a private spot in the back so it was something of a trek to the car. It was nice to have a quiet outside table & chairs. Once the renovations are done, it should be a really great place.

Reviewed on Jan 29, 2026

Opens in a new windowSeashell Motel
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More 4 star hotels in Key West

Key West Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Key West luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Key West to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Key West will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Key West, and plan your next opulent escape.


Key West hotels essential information

Accommodation
2,768 hotels
Lowest Price
$284
Highest Price
$944
Popular hotels
Oceans Edge Key West Resort, Hotel & Marina, The Marker Key West Harbor Resort, Casa Marina Key West, Curio Collection by Hilton, Southernmost Beach Resort and Guesthouses, H2O Suites - Adults Only, Seashell Motel, Southernmost House, Fairfield Inn & Suites by Marriott Key West at the Keys Collection

Popular Luxury Stays in Key West

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