Explore 64 Luxury Hotels in Key West

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Best Luxury Hotels in Key West

H2O Suites - Adults Only

H2O Suites - Adults Only

1212 Simonton Street Key West FL
$789 nightly
The price is $888 total per night from Jan 26 to Jan 27
$888 total
Jan 26 - Jan 27
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Business travelers can take advantage of the laundry service. There's a gym on site, and ...
9.8/10 Exceptional! (583 reviews)
Immaculate, beautifully decorated, warm and friendly staff. The welcome congratulation and champagne waiting for our arrival.

Reviewed on Dec 21, 2025

Opens in a new windowH2O Suites - Adults Only
Southernmost House

Southernmost House

1400 Duval Street Key West FL
$802 nightly
The price is $902 total per night from Feb 9 to Feb 10
$902 total
Feb 9 - Feb 10
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Guests will appreciate free perks like continental breakfast and WiFi in public areas. Self ...
9.4/10 Exceptional! (999 reviews)
Fun place, great location, great staff.

Reviewed on Jan 19, 2026

Opens in a new windowSouthernmost House
The Marker Key West Harbor Resort

The Marker Key West Harbor Resort

200 William Street Key West FL
Fully refundableReserve now, pay when you stay
$483 nightly
The price is $543 total per night from Jan 26 to Jan 27
$543 total
Jan 26 - Jan 27
Total with taxes and fees
This smoke-free hotel features 3 outdoor pools, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
9/10 Wonderful! (1,004 reviews)
Very nice hotel and good location. The room was a nice size and clean. Pools and pool bar are nice. Live music at the pool was fun/cool. The food is very average.

Reviewed on Jan 16, 2026

Opens in a new windowThe Marker Key West Harbor Resort
Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

5950 Peninsular Avenue Key West FL
Fully refundableReserve now, pay when you stay
$416 nightly
The price is $468 total per night from Jan 26 to Jan 27
$468 total
Jan 26 - Jan 27
Total with taxes and fees
A marina, 6 outdoor pools, and a 24-hour gym are all featured at this smoke-free hotel. Business travelers can take advantage of the free WiFi in public areas. ...
8.8/10 Excellent! (1,780 reviews)
Had a wonderful view from our room. Shuttle is super convenient to Key West! Pools are very clean and live music was fantastic. Already booked for next year 😊

Reviewed on Jan 20, 2026

Opens in a new windowOceans Edge Key West Resort, Hotel & Marina
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

1319 Duval Street Key West FL
Fully refundable
$473 nightly
The price is $532 total per night from Jan 26 to Jan 27
$532 total
Jan 26 - Jan 27
Total with taxes and fees
This hotel features a full-service spa, 3 outdoor pools, and a restaurant. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Traveling ...
8.6/10 Excellent! (3,012 reviews)
Loved everything about it! Absolutely beautiful sunsets!!! We had a wonderful time!

Reviewed on Jan 22, 2026

Opens in a new windowSouthernmost Beach Resort and Guesthouses
Fairfield Inn & Suites by Marriott Key West at the Keys Collection

Fairfield Inn & Suites by Marriott Key West at the Keys Collection

3852 North Roosevelt Boulevard Key West FL
$445 nightly
The price is $501 total per night from Feb 1 to Feb 2
$501 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
8.4/10 Very Good! (1,001 reviews)
Smooth and friendly check in. They also followed up with us to ensure our room was fine.

Reviewed on Jan 19, 2026

Opens in a new windowFairfield Inn & Suites by Marriott Key West at the Keys Collection
Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton

1500 Reynolds Street Key West FL
Fully refundableReserve now, pay when you stay
$507 nightly
The price is $571 total per night from Feb 8 to Feb 9
$571 total
Feb 8 - Feb 9
Total with taxes and fees
A private beach, a full-service spa, and 2 outdoor pools are all featured at this smoke-free resort. Relax with sun loungers and beach umbrellas, and cool off ...
8.2/10 Very Good! (517 reviews)
Beautiful historic hotel, room was spacious, lots of amenities, friendly staff, terrific views, can walk to town.

Reviewed on Jan 20, 2026

Opens in a new windowCasa Marina Key West, Curio Collection by Hilton
Seashell Motel

Seashell Motel

718 South Street Key West FL
Fully refundableReserve now, pay when you stay
$274 nightly
The price is $308 total per night from Jan 26 to Jan 27
$308 total
Jan 26 - Jan 27
Total with taxes and fees
This hostel doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, a picnic area, and luggage storage are also on offer.
7.8/10 Good! (1,001 reviews)
Check in was great and friendly. Walking distance to the beach. Air conditioning froze out my husband. Hotel was under construction but still very clean and kept. Would definitely stay again.

Reviewed on Jan 17, 2026

Opens in a new windowSeashell Motel
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More 4 star hotels in Key West

Key West Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Key West luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Key West to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Key West will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Key West, and plan your next opulent escape.


Key West hotels essential information

Accommodation
2,768 hotels
Lowest Price
$308
Highest Price
$902
Popular hotels
Oceans Edge Key West Resort, Hotel & Marina, The Marker Key West Harbor Resort, Casa Marina Key West, Curio Collection by Hilton, Southernmost Beach Resort and Guesthouses, H2O Suites - Adults Only, Seashell Motel, Southernmost House, Fairfield Inn & Suites by Marriott Key West at the Keys Collection

Popular Luxury Stays in Key West

Recent Key West Hotel Reviews By Fellow Wanderers

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