Explore 64 Luxury Hotels in Key West

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Best Luxury Hotels in Key West

H2O Suites - Adults Only

H2O Suites - Adults Only

1212 Simonton Street Key West FL
$559 nightly
The price is $629 total per night from Jan 4 to Jan 5
$629 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Business travelers can take advantage of the laundry service. There's a gym on site, and ...
9.8/10 Exceptional! (582 reviews)
Immaculate, beautifully decorated, warm and friendly staff. The welcome congratulation and champagne waiting for our arrival.

Reviewed on Dec 21, 2025

Opens in a new windowH2O Suites - Adults Only
Southernmost House

Southernmost House

1400 Duval Street Key West FL
$450 nightly
The price is $506 total per night from Jan 14 to Jan 15
$506 total
Jan 14 - Jan 15, 2026
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Unwind with a drink at the poolside bar and enjoy perks like free continental breakfast ...
9.4/10 Exceptional! (1,000 reviews)
Room spotless and staff were wonderful!

Reviewed on Dec 16, 2025

Opens in a new windowSouthernmost House
The Marker Key West Harbor Resort

The Marker Key West Harbor Resort

200 William Street Key West FL
Fully refundableReserve now, pay when you stay
$438 nightly
The price is $492 total per night from Jan 14 to Jan 15
$492 total
Jan 14 - Jan 15, 2026
Total with taxes and fees
This smoke-free hotel features 3 outdoor pools, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
9/10 Wonderful! (1,003 reviews)
Perfect location.. close to the wharf for the best dining experience.

Reviewed on Dec 20, 2025

Opens in a new windowThe Marker Key West Harbor Resort
Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

5950 Peninsular Avenue Key West FL
Fully refundableReserve now, pay when you stay
$292 nightly
The price is $328 total per night from Jan 26 to Jan 27
$328 total
Jan 26 - Jan 27, 2026
Total with taxes and fees
A marina, 6 outdoor pools, and a 24-hour gym are all featured at this smoke-free hotel. Business travelers can take advantage of the free WiFi in public areas. ...
8.8/10 Excellent! (1,757 reviews)
Great View

Reviewed on Dec 22, 2025

Opens in a new windowOceans Edge Key West Resort, Hotel & Marina
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

1319 Duval Street Key West FL
Fully refundable
$360 nightly
The price is $405 total per night from Jan 13 to Jan 14
$405 total
Jan 13 - Jan 14, 2026
Total with taxes and fees
This hotel features a full-service spa, 3 outdoor pools, and a restaurant. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Traveling ...
8.6/10 Excellent! (2,938 reviews)
Amazing 👌

Reviewed on Dec 22, 2025

Opens in a new windowSouthernmost Beach Resort and Guesthouses
Fairfield Inn & Suites by Marriott Key West at the Keys Collection

Fairfield Inn & Suites by Marriott Key West at the Keys Collection

3852 North Roosevelt Boulevard Key West FL
Fully refundableReserve now, pay when you stay
$262 nightly
The price is $295 total per night from Jan 11 to Jan 12
$295 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
8.4/10 Very Good! (1,007 reviews)
Great place, close to everything, cleaned

Reviewed on Dec 27, 2025

Opens in a new windowFairfield Inn & Suites by Marriott Key West at the Keys Collection
Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton

1500 Reynolds Street Key West FL
Fully refundableReserve now, pay when you stay
$545 nightly
The price is $613 total per night from Jan 12 to Jan 13
$613 total
Jan 12 - Jan 13, 2026
Total with taxes and fees
A private beach, a full-service spa, and 2 outdoor pools are all featured at this smoke-free resort. Relax with sun loungers and beach umbrellas, and cool off ...
8.2/10 Very Good! (482 reviews)
The view was almost spectacular except the hotel has permanently parked some kind of van right outside between the ocean view patios and the beach. It was there all week during our stay. We were on the second floor so it was really detracting from the view we paid for.

Reviewed on Dec 21, 2025

Opens in a new windowCasa Marina Key West, Curio Collection by Hilton
Seashell Motel

Seashell Motel

718 South Street Key West FL
Fully refundableReserve now, pay when you stay
$241 nightly
The price is $271 total per night from Jan 11 to Jan 12
$271 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
This hostel doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, a picnic area, and luggage storage are also on offer.
7.8/10 Good! (1,001 reviews)
up against neighbors parking lot. the only truck there over night parks as close to the motel as possible. the bushes are overgrown and there is no room to get to your room. i broke my bike mirror squeezing through. if they trim the bushes way back it will be fine

Reviewed on Dec 19, 2025

Opens in a new windowSeashell Motel
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More 4 star hotels in Key West

Key West Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Key West luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Key West to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Key West will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Key West, and plan your next opulent escape.


Key West hotels essential information

Accommodation
2,773 hotels
Lowest Price
$271
Highest Price
$629
Popular hotels
Oceans Edge Key West Resort, Hotel & Marina, The Marker Key West Harbor Resort, Casa Marina Key West, Curio Collection by Hilton, Southernmost Beach Resort and Guesthouses, H2O Suites - Adults Only, Seashell Motel, Southernmost House, Fairfield Inn & Suites by Marriott Key West at the Keys Collection

Popular Luxury Stays in Key West

Recent Key West Hotel Reviews By Fellow Wanderers

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