Explore 64 Luxury Hotels in Key West

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Best Luxury Hotels in Key West

H2O Suites - Adults Only

H2O Suites - Adults Only

1212 Simonton Street, Key West, FL
$409 nightly
The price is $460 total per night from Nov 30 to Dec 1
$460 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Business travelers can take advantage of the laundry service. There's a gym on site, and ...
9.8/10 Exceptional! (573 reviews)
Great staff, spacious room, clean grounds

Reviewed on Nov 3, 2025

Opens in a new windowH2O Suites - Adults Only
Southernmost House

Southernmost House

1400 Duval Street, Key West, FL
$370 nightly
The price is $416 total per night from Dec 7 to Dec 8
$416 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Unwind with a drink at the poolside bar and enjoy perks like free continental breakfast ...
9.2/10 Wonderful! (1,000 reviews)
The pool /ocean view was beautiful- clean - and so private!! Pool was open for night swimming until 10pm -which was so relaxing!! Bar/restaurant on the premises - comp to your room! Get the Lobster pizza!! Beautiful sunrise viewing! Rooms are clean and cozy! Nice towels and crisp clean bedding. European ...

Reviewed on Oct 14, 2025

Opens in a new windowSouthernmost House
The Marker Key West Harbor Resort

The Marker Key West Harbor Resort

200 William Street, Key West, FL
Fully refundableReserve now, pay when you stay
$295 nightly
The price is $332 total per night from Dec 2 to Dec 3
$332 total
Dec 2 - Dec 3
Total with taxes and fees
This smoke-free hotel features 3 outdoor pools, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
9/10 Wonderful! (1,001 reviews)
Everything was good.

Reviewed on Nov 8, 2025

Opens in a new windowThe Marker Key West Harbor Resort
Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

5950 Peninsular Avenue, Key West, FL
Fully refundableReserve now, pay when you stay
$208 nightly
The price is $234 total per night from Nov 17 to Nov 18
$234 total
Nov 17 - Nov 18
Total with taxes and fees
A marina, 6 outdoor pools, and a 24-hour gym are all featured at this smoke-free hotel. Business travelers can take advantage of the free WiFi in public areas. ...
8.8/10 Excellent! (1,732 reviews)
Excellent

Reviewed on Nov 7, 2025

Opens in a new windowOceans Edge Key West Resort, Hotel & Marina
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

1319 Duval Street, Key West, FL
Fully refundable
$242 nightly
The price is $272 total per night from Nov 30 to Dec 1
$272 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features a full-service spa, 3 outdoor pools, and a restaurant. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Traveling ...
8.6/10 Excellent! (2,854 reviews)
We loved our stay at Southernmost Beach Resort so much that we added an extra day to our trip! Alan was so helpful in getting us set up initially, and then working out adding another night in the same room. We walked everywhere since the resort is in such a great location and we loved utilizing all ...

Reviewed on Nov 5, 2025

Opens in a new windowSouthernmost Beach Resort and Guesthouses
Fairfield Inn & Suites by Marriott Key West at the Keys Collection

Fairfield Inn & Suites by Marriott Key West at the Keys Collection

3852 North Roosevelt Boulevard, Key West, FL
Fully refundableReserve now, pay when you stay
$136 nightly
The price is $153 total per night from Nov 17 to Nov 18
$153 total
Nov 17 - Nov 18
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
8.4/10 Very Good! (1,002 reviews)
Very nice suite, wish there was a light by tv in bedroom to make coffee

Reviewed on Nov 6, 2025

Opens in a new windowFairfield Inn & Suites by Marriott Key West at the Keys Collection
Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton

1500 Reynolds Street, Key West, FL
Fully refundableReserve now, pay when you stay
$307 nightly
The price is $346 total per night from Dec 1 to Dec 2
$346 total
Dec 1 - Dec 2
Total with taxes and fees
A private beach, a full-service spa, and 2 outdoor pools are all featured at this smoke-free resort. Relax with sun loungers and beach umbrellas, and cool off ...
8.2/10 Very Good! (424 reviews)
Room was nice and clean, very welcoming and accommodating. Food was delicious!

Reviewed on Nov 7, 2025

Opens in a new windowCasa Marina Key West, Curio Collection by Hilton
Seashell Motel

Seashell Motel

718 South Street, Key West, FL
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $122 total per night from Nov 11 to Nov 12
$122 total
Nov 11 - Nov 12
Total with taxes and fees
This hostel doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, a picnic area, and luggage storage are also on offer.
7.8/10 Good! (1,001 reviews)
The rooms are small but very clean. I’ve stayed here a few times and it’s always been nice.

Reviewed on Oct 28, 2025

Opens in a new windowSeashell Motel
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More 4 star hotels in Key West

Key West Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Key West luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Key West to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Key West will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Key West, and plan your next opulent escape.


Key West hotels essential information

Accommodation
2,760 hotels
Lowest Price
$122
Highest Price
$514
Popular hotels
Oceans Edge Key West Resort, Hotel & Marina, The Marker Key West Harbor Resort, Casa Marina Key West, Curio Collection by Hilton, Southernmost Beach Resort and Guesthouses, H2O Suites - Adults Only, Seashell Motel, Southernmost House, Fairfield Inn & Suites by Marriott Key West at the Keys Collection

Popular Luxury Stays in Key West

Recent Key West Hotel Reviews By Fellow Wanderers

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