Explore the best 2025 4 Star Hotels Hotels in Key West Historic District
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Top Key West Historic District 4 Star hotels

Southernmost Beach Resort and Guesthouses
1319 Duval Street, Key West, FL
Free Cancellation
$229 nightly
The price is $258 total per night
$258 total
Sep 4 - Sep 5
Total with taxes and fees
This hotel features a full-service spa, 3 outdoor pools, and a restaurant. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Traveling for business? Take advantage of the 24-hour business center, laundry service, and conference space.
Pool
Spa

Hyatt Centric Key West Resort and Spa
601 Front St, Key West, FL
Free Cancellation
Reserve now, pay when you stay
$242 nightly
The price is $272 total per night
$272 total
Sep 2 - Sep 3
Total with taxes and fees
This eco-certified resort features a full-service spa, a marina, and a restaurant. Enjoy the outdoor pool and perks like free WiFi. Enjoy the 24-hour gym and unwind at the bar/lounge and poolside bar.
Pool
Spa

Pier House Resort & Spa
1 Duval St, Key West, FL
Free Cancellation
Reserve now, pay when you stay
$381 nightly
The price is $429 total per night
$429 total
Sep 1 - Sep 2
Total with taxes and fees
This smoke-free resort features a private beach, a full-service spa, and a restaurant. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Traveling on business? Take advantage of the 2 conference rooms, business center, and express check-in.
On private beach
Pool

Casa Marina Key West, Curio Collection by Hilton
1500 Reynolds Street, Key West, FL
Free Cancellation
Reserve now, pay when you stay
$274 nightly
The price is $308 total per night
$308 total
Sep 2 - Sep 3
Total with taxes and fees
A private beach, a full-service spa, and 2 outdoor pools are all featured at this smoke-free resort. Relax with sun loungers and beach umbrellas, and cool off with a drink at the beachside bar. Enjoy the gym and perks like free WiFi.
On private beach
Pool

Opal Key Resort & Marina, Key West
245 Front Street, Key West, FL
Free Cancellation
Reserve now, pay when you stay
$294 nightly
The price is $331 total per night
$331 total
Aug 24 - Aug 25
Total with taxes and fees
A marina, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the outdoor pool and visit the 3 bars/lounges and poolside bar for drinks.
Pool
Hot Tub

Winslow's Bungalows - Key West Historic Inns
725 Truman Avenue, Key West, FL
Free Cancellation
Reserve now, pay when you stay
$239 nightly
The price is $268 total per night
$268 total
Sep 2 - Sep 3
Total with taxes and fees
This smoke-free hotel features 3 outdoor pools, a bar/lounge, and a poolside bar. Guests will appreciate free perks like continental breakfast and WiFi in public areas. Self parking, a garden, and luggage storage are also offered.
Pool
Breakfast included

The Reach Key West, Curio Collection by Hilton
1435 Simonton Street, Key West, FL
Free Cancellation
Reserve now, pay when you stay
$277 nightly
The price is $312 total per night
$312 total
Sep 15 - Sep 16
Total with taxes and fees
This resort features a private beach, a full-service spa, and a restaurant. Traveling on business? Take advantage of the express check-out, laundry service, and valet parking. Enjoy the outdoor pool and unwind at the bar/lounge and poolside bar.
On private beach
Pool

La Concha Key West, Autograph Collection
430 Duval St, Key West, FL
Free Cancellation
Reserve now, pay when you stay
$208 nightly
The price is $234 total per night
$234 total
Sep 4 - Sep 5
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, and valet parking. There's a poolside bar on site, and a 24-hour front desk and concierge services are also provided.
Pool
Pet friendly

The Marker Key West Harbor Resort
200 William Street, Key West, FL
Free Cancellation
Reserve now, pay when you stay
$226 nightly
The price is $254 total per night
$254 total
Sep 4 - Sep 5
Total with taxes and fees
This eco-certified hotel features 3 outdoor pools, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's a bar/lounge on site, and a 24-hour front desk and concierge services are also provided.
Pool
Pet friendly

Bishop Hotel Key West
822 Fleming St, Key West, FL
This guesthouse's 2 outdoor pools and hot tub are among the featured amenities. Unwind with a drink at the poolside bar and enjoy perks like free continental breakfast and free WiFi. There's luggage storage and multilingual staff can provide around-the-clock assistance.
Pool
Hot Tub

Santa Maria Suites
1401 Simonton St, Key West, FL
$308 nightly
The price is $347 total per night
$347 total
Sep 22 - Sep 23
Total with taxes and fees
This smoke-free resort features 2 outdoor pools, a gym, and a restaurant. Relax with a drink at the bar/lounge and enjoy perks like free WiFi. There's a poolside bar on site, and a 24-hour front desk and laundry facilities are also provided.
Pool
Free WiFi

Ocean Key Resort - A Noble House Resort
Zero Duval St., Key West, FL
Free Cancellation
Reserve now, pay when you stay
$272 nightly
The price is $306 total per night
$306 total
Sep 8 - Sep 9
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free resort. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, and valet parking. Enjoy the 24-hour gym and visit the 3 bars/lounges and poolside bar for drinks.
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See all available properties in Key West Historic District
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Key West Historic District hotels essential information
Accommodation | 1,718 hotels |
---|---|
Lowest Price | $234 |
Highest Price | $429 |
Popular hotels | Southernmost Beach Resort and Guesthouses, Hyatt Centric Key West Resort and Spa, Pier House Resort & Spa, Casa Marina Key West, Curio Collection by Hilton, Opal Key Resort & Marina, Key West, Winslow's Bungalows - Key West Historic Inns, The Reach Key West, Curio Collection by Hilton, La Concha Key West, Autograph Collection, The Marker Key West Harbor Resort, Bishop Hotel Key West, Santa Maria Suites, Ocean Key Resort - A Noble House Resort |
Recent Key West Historic District hotel reviews by fellow wanderers

Opal Key Resort & Marina, Key West
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"The location is great to experience the highlights of Key West: Mallory Square, Duval St, and the numerous historical sights, all within walking distance. The facility is clean, and the staff accomodating and welcoming."
A verified traveler stayed at Opal Key Resort & Marina, Key West
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