Find & Compare 28 Adults-Only Hotels & Resorts in Key West With Rates at from $129

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Top Adults Only Resorts in Key West

The Independent Inn - Formerly Heron House Court

The Independent Inn - Formerly Heron House Court

412 Frances St Key West FL
$139 nightly
The price is $152 total per night from Sep 13 to Sep 14
$152 total
Sep 13 - Sep 14
Total with taxes and fees
This guesthouse features an outdoor pool and a rooftop terrace. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A terrace, ...
9/10 Wonderful! (1,000 reviews)
"We didn't have dishes in our kitchens. Everything else was good 😊"

Reviewed on Sep 11, 2026

Opens in a new windowThe Independent Inn - Formerly Heron House Court
The Cabana Inn Key West - Adults Only

The Cabana Inn Key West - Adults Only

413 Applerouth Lane Key West FL
Fully refundableReserve now, pay when you stay
$165 nightly
The price is $186 total per night from Sep 22 to Sep 23
$186 total
Sep 22 - Sep 23
Total with taxes and fees
This guesthouse features an outdoor pool and a hot tub. Enjoy the free continental breakfast each morning. Self parking, a terrace, and a garden are also ...
9/10 Wonderful! (1,002 reviews)
"Excellent spot to stay right off Duval street...authentic Key West vibe"

Reviewed on Sep 11, 2026

Opens in a new windowThe Cabana Inn Key West - Adults Only
The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only

525 United Street Key West FL
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $129 total per night from Sep 14 to Sep 15
$129 total
Sep 14 - Sep 15
Total with taxes and fees
This hotel's 2 outdoor pools and hot tub are among the featured amenities. Enjoy the free continental breakfast each morning. Self parking, a coffee shop, and ...
8.4/10 Very Good! (1,436 reviews)
"Evething was good This hotels is closed to the beaches,great location"

Reviewed on Sep 10, 2026

Opens in a new windowThe Southernmost Inn - Adults Only
Paradise Inn Key West - Adults Only

Paradise Inn Key West - Adults Only

819 Simonton Street Key West FL
Fully refundableReserve now, pay when you stay
$182 nightly
The price is $205 total per night from Sep 21 to Sep 22
$205 total
Sep 21 - Sep 22
Total with taxes and fees
This hotel features an outdoor pool and a hot tub. Enjoy the free self-serve breakfast each morning. Self parking, a terrace, and a garden are also offered.
Opens in a new windowParadise Inn Key West - Adults Only
Heron House - Adult Only

Heron House - Adult Only

512 Simonton St Key West FL
$146 nightly
The price is $164 total per night from Sep 13 to Sep 14
$164 total
Sep 13 - Sep 14
Total with taxes and fees
This bed & breakfast features an outdoor pool and a rooftop terrace. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A ...
Opens in a new windowHeron House - Adult Only
Southernmost House - Adult Exclusive

Southernmost House - Adult Exclusive

1400 Duval Street Key West FL
$261 nightly
The price is $294 total per night from Oct 1 to Oct 2
$294 total
Oct 1 - Oct 2
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. WiFi in public areas is free. Self parking, a terrace, and a picnic area are also ...
Opens in a new windowSouthernmost House - Adult Exclusive
 Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

1118 Fleming St Key West FL
$143 nightly
The price is $161 total per night from Sep 14 to Sep 15
$161 total
Sep 14 - Sep 15
Total with taxes and fees
This hotel features an outdoor pool and a hot tub. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A business center, ...
Opens in a new window Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
Ridley House - Key West Historic Inns

Ridley House - Key West Historic Inns

601 Caroline St Key West FL
Fully refundableReserve now, pay when you stay
$245 nightly
The price is $276 total per night from Sep 13 to Sep 14
$276 total
Sep 13 - Sep 14
Total with taxes and fees
An outdoor pool is featured at this hotel, along with free WiFi in public areas and luggage storage. Enjoy the free buffet breakfast each morning. Concierge ...
Opens in a new windowRidley House - Key West Historic Inns
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton

1500 Reynolds Street Key West FL
$287 nightly
The price is $323 total per night from Sep 22 to Sep 23
$323 total
Sep 22 - Sep 23
Total with taxes and fees
8.4/10 Very Good! (905 reviews)

Popular Adults Only Stays in Key West

Book a stay at the best Key West adult only resorts

How can I find the best adults-only resorts in Key West?


Enter your travel dates, hit search, and click on the hotel resorts filter to compare prices, ratings, and genuine customer reviews from fantastic Key West adults-only resorts.


How can I find adults-only all-inclusive resorts in Key West?


Click on our all-inclusive filter to see the latest deals on an enticing selection of adults only all-inclusive resorts and hotels in Key West. It’s that simple.


How much do Key West adults-only hotels cost?


Prices start at just $129 a night, going up to $323 for luxury adults-only accommodation. Prices and availability are subject to change. Additional terms may apply.


When is the best time for an adult getaway to Key West?


In , there’s loads going on and a great atmosphere. A super-popular time for a romantic adult-only getaway is Valentine's weekend in Key West.


Are there any cheap couples’ resorts in Key West?


To find cheaper accommodation in Key West, order your search results by lowest price to see wallet friendlier stays first. You can use the budget filter, too. If your travel dates are flexible, visit in , when prices tend to be lower.


How can I find adults-only spa resorts in Key West?


Click on our spa filter under amenities on your search results page to see the spa resorts and hotels that whisk you away to a world of pampering and relaxation—just as you deserve.


What are some great things to do in Key West for adults?


Whether you’re taking a break from work, family, kids, or just the rigor of daily life, an adults-only break is the perfect opportunity to relax. Explore Key West by booking an excursion, chill by the pool with your loved one, and enjoy romantic cocktails and evening meals by candlelight.


How can I find the best Key West adults-only hotel deals?


With Travelocity, you can see the latest deals simply by entering your travel dates and hitting search. Use the budget filter to narrow down accommodation in your price range, check out our customer ratings to compare deals, too, and when you download the free Travelocity appOpens in a new window, you also get great member discounts.  


Can I get free cancellation on my adults only hotel in Key West?


Many adults only hotels in Key West offer free cancellation. Canceling a booking is simple: Log into your My TripsOpens in a new window page and go to your itinerary to see your options. Visit our Customer Support PortalOpens in a new window for more details. If you booked a property offering free cancellation or took up our reserve now, pay later offer then you may not be out of pocket either.  


Why should I book my adults only resort in Key West with Travelocity?


With Travelocity, you get a fantastic selection of Key West adults only hotel and resort deals in just one click. You can save even more when you bundle your flights and car rental together, too. So, escape for an unforgettable adults-only vacation and book your dream hotel today.


Recent Key West hotel reviews by fellow wanderers