Find & Compare 28 Adults-Only Hotels & Resorts in Key West With Rates at from $156

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Top Adults Only Resorts in Key West

 Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

1118 Fleming St, Key West, FL
$348 nightly
The price is $391 total per night from Oct 27 to Oct 28
$391 total
Oct 27 - Oct 28
Total with taxes and fees
This hotel features an outdoor pool and a hot tub. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A business center, ...
9.8/10 Exceptional! (119 reviews)
"Beautiful property. Staff is so kind. Can’t wait to return."

Reviewed on Oct 5, 2025

Opens in a new window Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
Southernmost House

Southernmost House

1400 Duval Street, Key West, FL
$282 nightly
The price is $317 total per night from Oct 27 to Oct 28
$317 total
Oct 27 - Oct 28
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Unwind with a drink at the poolside bar and enjoy perks like free continental breakfast ...
9.2/10 Wonderful! (1,007 reviews)
"The pool /ocean view was beautiful- clean - and so private!! Pool was open for night swimming until 10pm -which was so relaxing!! Bar/restaurant on the premises - comp to your room! Get the Lobster pizza!! Beautiful sunrise viewing! Rooms are clean and cozy! Nice towels and crisp clean bedding. European ..."

Reviewed on Oct 14, 2025

Opens in a new windowSouthernmost House
Ridley House - Key West Historic Inns

Ridley House - Key West Historic Inns

601 Caroline St, Key West, FL
Fully refundableReserve now, pay when you stay
$228 nightly
The price is $256 total per night from Oct 27 to Oct 28
$256 total
Oct 27 - Oct 28
Total with taxes and fees
An outdoor pool is featured at this hotel, along with free WiFi in public areas and luggage storage. Enjoy the free buffet breakfast each morning. Concierge ...
9.2/10 Wonderful! (826 reviews)
"Clean room, includes breakfast, 2m walking distance for everything; like restaurants, bars, stores and marinas. Highly recommended."

Reviewed on Oct 13, 2025

Opens in a new windowRidley House - Key West Historic Inns
Paradise Inn Key West - Adults Only

Paradise Inn Key West - Adults Only

819 Simonton Street, Key West, FL
$140 nightly
The price is $157 total per night from Oct 26 to Oct 27
$157 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an outdoor pool and a hot tub. Enjoy the free continental breakfast each morning. Self parking, a terrace, and a garden are also ...
9/10 Wonderful! (1,010 reviews)
"Clean room"

Reviewed on Oct 16, 2025

Opens in a new windowParadise Inn Key West - Adults Only
Heron House - Adult Only

Heron House - Adult Only

512 Simonton St, Key West, FL
$221 nightly
The price is $249 total per night from Oct 26 to Oct 27
$249 total
Oct 26 - Oct 27
Total with taxes and fees
This bed & breakfast features an outdoor pool and a rooftop terrace. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A ...
9/10 Wonderful! (1,136 reviews)
"Great place to stay very convenient and quaint."

Reviewed on Oct 15, 2025

Opens in a new windowHeron House - Adult Only
Heron House Court - Adult Only

Heron House Court - Adult Only

412 Frances St, Key West, FL
$198 nightly
The price is $223 total per night from Oct 26 to Oct 27
$223 total
Oct 26 - Oct 27
Total with taxes and fees
This guesthouse features an outdoor pool and a rooftop terrace. WiFi in public areas is free. A terrace, a garden, and luggage storage are also on offer.
8.8/10 Excellent! (1,008 reviews)
"Great location!"

Reviewed on Oct 15, 2025

Opens in a new windowHeron House Court - Adult Only
The Cabana Inn Key West - Adults Only

The Cabana Inn Key West - Adults Only

413 Applerouth Lane, Key West, FL
$158 nightly
The price is $178 total per night from Oct 27 to Oct 28
$178 total
Oct 27 - Oct 28
Total with taxes and fees
This guesthouse features an outdoor pool and a hot tub. Enjoy the free continental breakfast each morning. Self parking, a terrace, and a garden are also ...
8.8/10 Excellent! (1,011 reviews)
"This place is in the perfect location. The staff is great. The breakfast was exactly what we needed. The property is beautiful,quaint, well maintained and the bed was very comfortable."

Reviewed on Oct 17, 2025

Opens in a new windowThe Cabana Inn Key West - Adults Only
The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only

525 United Street, Key West, FL
$139 nightly
The price is $156 total per night from Oct 27 to Oct 28
$156 total
Oct 27 - Oct 28
Total with taxes and fees
This hotel's 2 outdoor pools and hot tub are among the featured amenities. Enjoy the free continental breakfast each morning. Self parking, a coffee shop, and ...
8.2/10 Very Good! (1,173 reviews)
"Room was cool and clean."

Reviewed on Oct 16, 2025

Opens in a new windowThe Southernmost Inn - Adults Only
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Search All-Inclusive Hotels in Key West

Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton

1500 Reynolds Street, Key West, FL
$263 nightly
The price is $295 total per night from Oct 29 to Oct 30
$295 total
Oct 29 - Oct 30
Total with taxes and fees
8.2/10 Very Good! (400 reviews)

Popular Adults Only Stays in Key West

Book a stay at the best Key West adult only resorts

How can I find the best adults-only resorts in Key West?


Enter your travel dates, hit search, and click on the hotel resorts filter to compare prices, ratings, and genuine customer reviews from fantastic Key West adults-only resorts.


How can I find adults-only all-inclusive resorts in Key West?


Click on our all-inclusive filter to see the latest deals on an enticing selection of adults only all-inclusive resorts and hotels in Key West. It’s that simple.


How much do Key West adults-only hotels cost?


Prices start at just $156 a night, going up to $391 for luxury adults-only accommodation. Prices and availability are subject to change. Additional terms may apply.


When is the best time for an adult getaway to Key West?


In , there’s loads going on and a great atmosphere. A super-popular time for a romantic adult-only getaway is Valentine's weekend in Key West.


Are there any cheap couples’ resorts in Key West?


To find cheaper accommodation in Key West, order your search results by lowest price to see wallet friendlier stays first. You can use the budget filter, too. If your travel dates are flexible, visit in , when prices tend to be lower.


How can I find adults-only spa resorts in Key West?


Click on our spa filter under amenities on your search results page to see the spa resorts and hotels that whisk you away to a world of pampering and relaxation—just as you deserve.


What are some great things to do in Key West for adults?


Whether you’re taking a break from work, family, kids, or just the rigor of daily life, an adults-only break is the perfect opportunity to relax. Explore Key West by booking an excursion, chill by the pool with your loved one, and enjoy romantic cocktails and evening meals by candlelight.


How can I find the best Key West adults-only hotel deals?


With Travelocity, you can see the latest deals simply by entering your travel dates and hitting search. Use the budget filter to narrow down accommodation in your price range, check out our customer ratings to compare deals, too, and when you download the free Travelocity appOpens in a new window, you also get great member discounts.  


Can I get free cancellation on my adults only hotel in Key West?


Many adults only hotels in Key West offer free cancellation. Canceling a booking is simple: Log into your My TripsOpens in a new window page and go to your itinerary to see your options. Visit our Customer Support PortalOpens in a new window for more details. If you booked a property offering free cancellation or took up our reserve now, pay later offer then you may not be out of pocket either.  


Why should I book my adults only resort in Key West with Travelocity?


With Travelocity, you get a fantastic selection of Key West adults only hotel and resort deals in just one click. You can save even more when you bundle your flights and car rental together, too. So, escape for an unforgettable adults-only vacation and book your dream hotel today.


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