Book Hotels in Effingham, SC

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Top Effingham hotels

Comfort Inn & Suites

Comfort Inn & Suites

2.5 out of 5
527 Woody Jones Blvd, Florence, SC
Fully refundableReserve now, pay when you stay
The price is $123 total per night from Aug 10 to Aug 11
$123 total
per night
Aug 10 - Aug 11
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
"Everything was great. Nice and quiet and friendly staff."

Reviewed on Jul 21, 2025

Comfort Inn & Suites
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road, Florence, SC
Fully refundableReserve now, pay when you stay
The price is $105 total per night from Aug 17 to Aug 18
$105 total
per night
Aug 17 - Aug 18
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. Enjoy ...
"Overall it was good. Front desk staff were very friendly. The breakfast was good. It was disappointing that the light shade in the room was loose and there was a stain on the ceiling in the dining area, so maintenance was not done well."

Reviewed on Jul 21, 2025

Park Inn by Radisson Florence, SC
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence, Florence, SC
Fully refundableReserve now, pay when you stay
The price is $116 total per night from Aug 4 to Aug 5
$116 total
per night
Aug 4 - Aug 5
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Would stay again
"Check in was fast and easy. The Hotel Lobby was clean and had a lounge and bar inside. We did not use the pool but there is one on the premises. The rooms were clean and well maintained. Bathroom was clean and fully stocked. Only thing I did not like was the parking. You have to drive down an alley ..."

Reviewed on Jul 21, 2025

Hyatt Place Florence Downtown
TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

3 out of 5
2650 Hospitality Boulevard, Florence, SC
Fully refundableReserve now, pay when you stay
The price is $125 total per night from Jul 27 to Jul 28
$125 total
per night
Jul 27 - Jul 28
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"thumbs up for pool, gym, laundry room, price!"

Reviewed on Jul 13, 2025

TownePlace Suites by Marriott Florence
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street, I-95 Exit 164, Florence, SC
Fully refundableReserve now, pay when you stay
The price is $79 total per night from Jul 27 to Jul 28
$79 total
per night
Jul 27 - Jul 28
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Nice and close to the interstate. Very nice comfortable and clean room. The price was budget friendly"

Reviewed on Jul 22, 2025

Howard Johnson by Wyndham Florence
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

3 out of 5
2123 W Lucas St, Florence, SC
Fully refundableReserve now, pay when you stay
The price is $108 total per night from Aug 17 to Aug 18
$108 total
per night
Aug 17 - Aug 18
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Comfortable room. Breakfast ended at 9 and I thought it was 10. Beyond that everything was good"

Reviewed on Jul 19, 2025

La Quinta Inn & Suites by Wyndham Florence
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr, Florence, SC
Fully refundableReserve now, pay when you stay
The price is $95 total per night from Aug 24 to Aug 25
$95 total
per night
Aug 24 - Aug 25
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Great place to rest and sleep after 11 hrs of driving."

Reviewed on Jul 20, 2025

Quality Inn & Suites Florence Civic Center
Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North

2 out of 5
2111 West Lucas St/I-95, I-95 & Hwy 52 Exit 164, Florence, SC
Fully refundableReserve now, pay when you stay
The price is $68 total per night from Jul 29 to Jul 30
$68 total
per night
Jul 29 - Jul 30
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this motel. Guests will appreciate free perks like on-the-go breakfast and ...
"Dated… but clean… could use a DEEP clean.. hair dryer must have been dropped and had a big piece missing. Someone could get hurt. Full breakfast was a joke… boiled eggs waffles…. But no water to drink… I felt safe so that’s a plus!"

Reviewed on Jul 7, 2025

Days Inn by Wyndham Florence/I-95 North
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr, Florence, SC
Fully refundableReserve now, pay when you stay
The price is $71 total per night from Jul 27 to Jul 28
$71 total
per night
Jul 27 - Jul 28
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"I would reserve again, but my wife has her own opinion."

Reviewed on Jul 20, 2025

Days Inn by Wyndham Florence Near Civic Center
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Effingham?
Family getaways are where treasured memories are made, but it's no secret that traveling with little ones can be tricky. These kid-friendly Effingham hotels come with perks designed to keep visitors of all ages relaxed and happy: Put your bags down at Cheerful home with plenty of privacy and entertainment room.. It comes with a fireplace, free WiFi and a knack for making families feel welcome. Otherwise, spend your Effingham break at Walking distance from one of South Carolinas top Medical centers.. Take advantage of free WiFi, clothes washing facilities and more here.
Where can I find cheap hotels in Effingham?
At Travelocity you'll find really nice hotels in Effingham at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Effingham rather than in Effingham. We may find you even better rates, too.
How do I find the best Effingham hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Effingham then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Effingham?
The cheapest hotel in Effingham is $68. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Effingham?
There are 129 hotels in Effingham on Travelocity.
What are the best hotels in Effingham?
Effingham has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Effingham for you!
When is the best time to visit Effingham?
If you want the joy of a fun-filled trip in peak season, visit Effingham during March, April and July. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, September and October.
When is the cheapest time to stay in Effingham?
Based on historic data is usually the cheapest month to visit Effingham. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Effingham?
There are multiple hotels in Effingham that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Effingham. We have plenty of kid-friendly hotels in Effingham to choose from on Travelocity!
Why book a hotel in Effingham through Travelocity?
Because we have the top hotels in Effingham! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Effingham on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Effingham hotel reviews by fellow wanderers

Comfort Inn & Suites

Comfort Inn & Suites

5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Everything was great. Nice and quiet and friendly staff. "
A verified traveler stayed at Comfort Inn & Suites
Comfort Inn & Suites
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