Book Hotels in Effingham, SC
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Top Effingham hotels

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
3440 W Radio Dr Florence SC
$131 nightly
The price is $147 total per night from Apr 12 to Apr 13
$147 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Breakfast was good.
Reviewed on Mar 29, 2026

Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
Fully refundable
$89 nightly
The price is $100 total per night from Apr 26 to Apr 27
$100 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. Enjoy ...
The pool was not open. But a very nice place for the money. Easy access from 95
Reviewed on Apr 6, 2026

Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
Fully refundable
$98 nightly
The price is $109 total per night from May 3 to May 4
$109 total
May 3 - May 4
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
Hadn’t stayed at a Comfort Inn & Suites before. Ran across this well rated location on a busy Easter Saturday when many locations were fully booked or only had king rooms remaining (we need 2 queens). Very pleased with this location! Everything from the bathroom to the carpet, foyer to hallways was ...
Reviewed on Apr 6, 2026

Hyatt Place Florence Downtown
100 East Evans Street Florence Florence SC
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $137 total per night from Apr 26 to Apr 27
$137 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Clean room great service
Reviewed on Apr 6, 2026

TownePlace Suites by Marriott Florence
2650 Hospitality Boulevard Florence SC
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $132 total per night from Apr 12 to Apr 13
$132 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
The water was shut off, could not shower or use the restroom. No compensation was offered.
Reviewed on Apr 7, 2026

Howard Johnson by Wyndham Florence
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $75 total per night from Apr 8 to Apr 9
$75 total
Apr 8 - Apr 9
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
It was reasonably priced but not quite as clean as I would have liked. We have stayed here before and it seems to have gone a little down hill.
Reviewed on Apr 7, 2026

SpringHill Suites by Marriott Florence
2670 Hospitality Blvd Florence SC
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $109 total per night from Apr 13 to Apr 14
$109 total
Apr 13 - Apr 14
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Yes, everything was great. Thank you
Reviewed on Apr 5, 2026

Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $104 total per night from Apr 12 to Apr 13
$104 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
We arrived late after 8 hours on the road to no one in the office. We called multiple times, rang the bell, and even just waited quietly. After 15 minutes with no help, I called the national office, which also attempted to get in touch with hotel staff. They even called management's emergency line ...
Reviewed on Apr 5, 2026

Microtel Inn & Suites by Wyndham Florence
1912 Enterprise Dr Florence SC
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $67 total per night from Apr 27 to Apr 28
$67 total
Apr 27 - Apr 28
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
I’ve stayed in Microtel Inns several times and have had zero complaints. I will never stay in this one again (Florence, SC). Musty smell, the bathroom looks like it was caulked by a first grader. Most if the electrical outlets have lost their tension and need replaced. Others have burn marks from ...
Reviewed on Apr 4, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent Effingham hotel reviews by fellow wanderers

TownePlace Suites by Marriott Florence
1 out of 5
Posted 10 hours ago
Travelocity Verified Review
"The water was shut off, could not shower or use the restroom. No compensation was offered."
A verified traveler stayed at TownePlace Suites by Marriott Florence
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