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Top Effingham hotels

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

2.5 out of 5
3440 W Radio Dr Florence SC
$131 nightly
The price is $147 total per night from Apr 12 to Apr 13
$147 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Breakfast was good.

Reviewed on Mar 29, 2026

Opens in a new windowHoliday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Fully refundable
$89 nightly
The price is $100 total per night from Apr 26 to Apr 27
$100 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. Enjoy ...
The pool was not open. But a very nice place for the money. Easy access from 95

Reviewed on Apr 6, 2026

Opens in a new windowPark Inn by Radisson Florence, SC
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
Fully refundable
$98 nightly
The price is $109 total per night from May 3 to May 4
$109 total
May 3 - May 4
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
Hadn’t stayed at a Comfort Inn & Suites before. Ran across this well rated location on a busy Easter Saturday when many locations were fully booked or only had king rooms remaining (we need 2 queens). Very pleased with this location! Everything from the bathroom to the carpet, foyer to hallways was ...

Reviewed on Apr 6, 2026

Opens in a new windowComfort Inn & Suites Florence Center Area
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $137 total per night from Apr 26 to Apr 27
$137 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Clean room great service

Reviewed on Apr 6, 2026

Opens in a new windowHyatt Place Florence Downtown
TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

3 out of 5
2650 Hospitality Boulevard Florence SC
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $132 total per night from Apr 12 to Apr 13
$132 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
The water was shut off, could not shower or use the restroom. No compensation was offered.

Reviewed on Apr 7, 2026

Opens in a new windowTownePlace Suites by Marriott Florence
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $75 total per night from Apr 8 to Apr 9
$75 total
Apr 8 - Apr 9
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
It was reasonably priced but not quite as clean as I would have liked. We have stayed here before and it seems to have gone a little down hill.

Reviewed on Apr 7, 2026

Opens in a new windowHoward Johnson by Wyndham Florence
SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence

3 out of 5
2670 Hospitality Blvd Florence SC
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $109 total per night from Apr 13 to Apr 14
$109 total
Apr 13 - Apr 14
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Yes, everything was great. Thank you

Reviewed on Apr 5, 2026

Opens in a new windowSpringHill Suites by Marriott Florence
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $104 total per night from Apr 12 to Apr 13
$104 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
We arrived late after 8 hours on the road to no one in the office. We called multiple times, rang the bell, and even just waited quietly. After 15 minutes with no help, I called the national office, which also attempted to get in touch with hotel staff. They even called management's emergency line ...

Reviewed on Apr 5, 2026

Opens in a new windowQuality Inn & Suites Florence Civic Center
Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence

2 out of 5
1912 Enterprise Dr Florence SC
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $67 total per night from Apr 27 to Apr 28
$67 total
Apr 27 - Apr 28
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
I’ve stayed in Microtel Inns several times and have had zero complaints. I will never stay in this one again (Florence, SC). Musty smell, the bathroom looks like it was caulked by a first grader. Most if the electrical outlets have lost their tension and need replaced. Others have burn marks from ...

Reviewed on Apr 4, 2026

Opens in a new windowMicrotel Inn & Suites by Wyndham Florence
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Effingham?
Family getaways are where treasured memories are made, but it's no secret that traveling with little ones can be tricky. These kid-friendly Effingham hotels come with perks designed to keep visitors of all ages relaxed and happy: Put your bags down at Cheerful home with plenty of privacy and entertainment room.. It comes with a fireplace, free WiFi and a knack for making families feel welcome. Otherwise, spend your Effingham break at Walking distance from one of South Carolinas top Medical centers.. Take advantage of free WiFi, clothes washing facilities and more here.
Where can I find cheap hotels in Effingham?
At Travelocity you'll find really nice hotels in Effingham at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Effingham rather than in Effingham. We may find you even better rates, too.
How do I find the best Effingham hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Effingham then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Effingham?
The cheapest hotel in Effingham is $67. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Effingham?
There are 162 hotels in Effingham on Travelocity.
What are the best hotels in Effingham?
Effingham has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Effingham for you!
When is the best time to visit Effingham?
If you want the joy of a fun-filled trip in peak season, visit Effingham during March, April and July. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, September and October.
When is the cheapest time to stay in Effingham?
Based on historic data is usually the cheapest month to visit Effingham. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Effingham?
There are multiple hotels in Effingham that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Effingham. We have plenty of kid-friendly hotels in Effingham to choose from on Travelocity!
Why book a hotel in Effingham through Travelocity?
Because we have the top hotels in Effingham! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Effingham on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

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