Book Hotels in Lake City, SC
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Top Lake City hotels
The Inn at the Crossroads
"Super bel hôtel ! Une belle découverte."
Reviewed on Jun 27, 2026
Comfort Inn & Suites Florence Center Area
"Staff was very friendly."
Reviewed on Jul 1, 2026
Quality Inn & Suites Florence Civic Center
"Upon arrival I found that the room was attractive, clean, and smelled fresh, no chemical smells or sticky surfaces. I love the colors and simple modern furnishings, comfy bed and fresh, clean bed clothes. I enjoyed being in the room! There was a nice size mini-fridge (with freezer area for ice packs), ..."
Reviewed on Jun 29, 2026
Courtyard by Marriott Florence
"Terrible experience I was traveling back to Florida with my dog, husband and baby. I stood in room 324 roaches in the room and the carpet super dirty. I told the staff and nobody paid attention to me, I was told a manager would reach out to me and nobody ever did. Please do not stay here."
Reviewed on Jun 29, 2026
Quality Inn & Suites Lake City
"No comments"
Reviewed on Jun 26, 2026
Days Inn by Wyndham Florence Near Civic Center
"It was ok but the staff was rude"
Reviewed on Jul 1, 2026
Florence Inn and Suites
"Clean room. Nice bed"
Reviewed on Jul 1, 2026
Days Inn by Wyndham Lake City
"The room was great. Very clean. The staff needs lessons in etiquette."
Reviewed on May 17, 2026
3-bedroom house in welcoming Lake City with cool AC
Cheap Lake City hotels
The Inn at the Crossroads
Lake City Hotel & Travel Guide
Within a 6-mile (10-kilometer) radius of the heart of Lake City, with Travelocity's reservations page you can find a limited, yet excellent selection of places to kick your feet up. Within an easy commute to Lake City, travelers will find 2 suitable lodging options.
If you are hoping to find a hotel that is no more than an easy walk from central Lake City, Days Inn Lake City and The Inn at the Crossroads will be perfect.
If you are in the downtown area of Lake City, it is around 13 miles (21 kilometers) to the Signature Boutique Hotel.
Would you like to go further afield? South Carolina Midlands boasts many impressive options. South Carolina Midlands is famous for rolling hills. Commonly visited visitor sights include historic mansions and gardens. In this fascinating part of United States of America adventurous visitors can partake in hiking.
35 miles (59 kilometers) to the northwest of Lake City, you can reach Bishopville, which is where you can enjoy South Carolina Cotton Museum and Lee State Park. A few Bishopville places to stay include the Americas Best Value Inn and Econo Lodge Bishopville. 40 miles (63 kilometers) northwest of Lake City, is Hartsville, which boasts the Fairfield Inn by Marriott Hartsville and Quality Inn. During your time in Hartsville, make your way to the Coker College and Hartsville Museum.
If you are into sports and like to watch thrilling games you and your family could take a trip to Myrtle Beach Speedway, which is found 45 miles (75 kilometers) to the east of Lake City. Find a Travelocity-listed hotel right in the thick of the action at the Bluegreen Vacations Harbour Lights, Ascend Resort Collection or the Hampton Inn Myrtle Beach West.
Florence Regional Airport is a primary arrival point for air travel, and is 25 miles (37 kilometers) from Lake City's downtown. Travelocity-listed accommodation nearby include Hotel Florence, an Ascend Hotel Collection Member and Motel 6 Florence Historic Downtown.
Frequently asked questions
Recent Lake City hotel reviews by fellow wanderers
Days Inn by Wyndham Florence Near Civic Center
"It was ok but the staff was rude"
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