Book Hotels in Pamplico, SC
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Top Pamplico hotels

Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $111 total per night from Jan 25 to Jan 26
$111 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
Front desk staff was wonderful/ professional and friendly. Hotel needs update-rooms, walls, floors are worn
Reviewed on Jan 8, 2026

Hampton Inn & Suites Florence Center
3000 W Radio Dr Florence SC
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $109 total per night from Jan 25 to Jan 26
$109 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...
Room was spotless! Bathroom was very clean as well.
Reviewed on Jan 3, 2026

Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
Fully refundable
$85 nightly
The price is $95 total per night from Jan 18 to Jan 19
$95 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. Enjoy ...
Room was clean and staff courteous
Reviewed on Jan 7, 2026

Hyatt Place Florence Downtown
100 East Evans Street Florence Florence SC
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $112 total per night from Jan 19 to Jan 20
$112 total
Jan 19 - Jan 20
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Check in was quick. Property is well managed and beautiful. Multiple dining choices that are walkable. Room was spacious and clean. Beds and pillow was super comfortable ! The downtown area is quaint! Only downside, parking is across and down the street.
Reviewed on Jan 6, 2026

Residence Inn Marriott Florence
2660 Hospitality Blvd Florence SC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $111 total per night from Jan 15 to Jan 16
$111 total
Jan 15 - Jan 16
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the free continental ...
I gave it four stars because they was a five dollar parking fee that’s charged on the credit card you leave for incidentals I was not aware of the parking fee. We only stayed one night so I guess it’s five dollars per night for parking. Other than that. Everything was great. Rooms were clean. Breakfast ...
Reviewed on Jan 5, 2026

TownePlace Suites by Marriott Florence
2650 Hospitality Boulevard Florence SC
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $107 total per night from Jan 18 to Jan 19
$107 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Clean and quiet room.
Reviewed on Jan 8, 2026

Howard Johnson by Wyndham Florence
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Jan 13 to Jan 14
$79 total
Jan 13 - Jan 14
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Check in was quick, efficient and friendly. The rooms had oleanty of space and were clean.
Reviewed on Jan 7, 2026

Tru by Hilton Florence I-95
2140 West Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $108 total per night from Jan 18 to Jan 19
$108 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Relax with a drink ...
My room was very spacious and clean and i enjoyed the surround sound tv and the floors and bathroom were clean. The staff was very nice.
Reviewed on Jan 5, 2026

La Quinta Inn & Suites by Wyndham Florence
2123 W Lucas St Florence SC
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $105 total per night from Jan 13 to Jan 14
$105 total
Jan 13 - Jan 14
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
The staff were very friendly. The entire building was very clean and inviting.
Reviewed on Jan 8, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Pamplico with star-rating
Check Pamplico Hotels by Star Rating

3 Star Hotels
13 properties
Frequently asked questions
Recent Pamplico hotel reviews by fellow wanderers

TownePlace Suites by Marriott Florence
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Clean and quiet room. "
A verified traveler stayed at TownePlace Suites by Marriott Florence
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