Book Hotels in Pamplico, SC
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Top Pamplico hotels

Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $112 total per night from Nov 19 to Nov 20
$112 total
Nov 19 - Nov 20
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
yes
Reviewed on Nov 15, 2025

Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $105 total per night from Dec 7 to Dec 8
$105 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. Enjoy ...
The hotel was a decent hotel . The curtains had a few stains but was overall clean
Reviewed on Nov 11, 2025

Hampton Inn & Suites Florence-North-I-95
1735 Stokes Road Florence SC
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $116 total per night from Nov 23 to Nov 24
$116 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Great breakfast
Reviewed on Nov 10, 2025

Hyatt Place Florence Downtown
100 East Evans Street Florence Florence SC
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $112 total per night from Nov 24 to Nov 25
$112 total
Nov 24 - Nov 25
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Great stay
Reviewed on Nov 14, 2025

TownePlace Suites by Marriott Florence
2650 Hospitality Boulevard Florence SC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $111 total per night from Dec 1 to Dec 2
$111 total
Dec 1 - Dec 2
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Friendly staff
Reviewed on Nov 15, 2025

Howard Johnson by Wyndham Florence
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $73 total per night from Nov 23 to Nov 24
$73 total
Nov 23 - Nov 24
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Room was clean
Reviewed on Nov 15, 2025

Aloft Florence
820 WOODY JONES BOULEVARD Florence SC
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $113 total per night from Nov 23 to Nov 24
$113 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Didn’t have breakfast but everything else was great
Reviewed on Nov 11, 2025

Tru by Hilton Florence I-95
2140 West Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Nov 30 to Dec 1
$106 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Relax with a drink ...
Clean room, Great Staff, Nice Breakfast
Reviewed on Nov 14, 2025

La Quinta Inn & Suites by Wyndham Florence
2123 W Lucas St Florence SC
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $115 total per night from Nov 18 to Nov 19
$115 total
Nov 18 - Nov 19
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
motel very clean. Staffs very professional. Breakfast very nice with hot food and coffee. Fresh water. Juice available with breakfasts. LOBBY and dining have inviting atmosphere
Reviewed on Nov 10, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Pamplico with star-rating
Check Pamplico Hotels by Star Rating

3 Star Hotels
13 properties
Frequently asked questions
Recent Pamplico hotel reviews by fellow wanderers
Home2 Suites by Hilton Florence, SC
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Spacious room with excellent amenities "
A verified traveler stayed at Home2 Suites by Hilton Florence, SC
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- Flights to Marion
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- Flights from Florence Regional
- American Airlines Charlotte (CLT) to Florence (FLO) flights
- American Airlines Greenville (GSP) to Florence (FLO) flights
- American Airlines Atlanta (ATL) to Florence (FLO) flights
- American Airlines Cleveland (CLE) to Florence (FLO) flights
- American Airlines New York (JFK) to Florence (FLO) flights
- American Airlines Chicago (ORD) to Florence (FLO) flights
- American Airlines Orlando (MCO) to Florence (FLO) flights
- American Airlines Phoenix (PHX) to Florence (FLO) flights
- American Airlines Tampa (TPA) to Florence (FLO) flights
- Delta Atlanta (ATL) to Florence (FLO) flights
- Delta New York (JFK) to Florence (FLO) flights
- Flights from Hartford (BDL) to Florence (FLO)
- Flights from Nashville (BNA) to Florence (FLO)
- Flights from Boise (BOI) to Florence (FLO)
- Flights from Baltimore (BWI) to Florence (FLO)
- Flights from Newark Liberty Intl. Airport (EWR) to Florence (FLO)
- Flights from Greenville (GSP) to Florence (FLO)
- Flights from Jacksonville (JAX) to Florence (FLO)
- Flights from Lexington (LEX) to Florence (FLO)
- Flights from Philadelphia (PHL) to Florence (FLO)
- Flights from Raleigh (RDU) to Florence (FLO)
- Flights from Fort Myers (RSW) to Florence (FLO)
- Flights from Savannah (SAV) to Florence (FLO)
- Flights from Tampa (TPA) to Florence (FLO)
- Flights from Knoxville (TYS) to Florence (FLO)

