Book Hotels in Pamplico, SC
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Top Pamplico hotels

Comfort Inn & Suites
527 Woody Jones Blvd, Florence, SC
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $112 total per night from Nov 16 to Nov 17
$112 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
Nice clean room, well off the road.
Reviewed on Nov 8, 2025

Park Inn by Radisson Florence, SC
1729 Mandeville Road, Florence, SC
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $105 total per night from Dec 7 to Dec 8
$105 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. Enjoy ...
Room was comfortable. I didn't utilize the breakfast
Reviewed on Nov 8, 2025

Hampton Inn & Suites Florence-North-I-95
1735 Stokes Road, Florence, SC
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $116 total per night from Nov 20 to Nov 21
$116 total
Nov 20 - Nov 21
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Great breakfast
Reviewed on Nov 10, 2025

Hyatt Place Florence Downtown
100 East Evans Street Florence, Florence, SC
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $112 total per night from Nov 24 to Nov 25
$112 total
Nov 24 - Nov 25
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Everything was great. The room were clean and staff was courteous.
Reviewed on Nov 2, 2025

Howard Johnson by Wyndham Florence
2038 W Lucas Street, I-95 Exit 164, Florence, SC
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $73 total per night from Nov 18 to Nov 19
$73 total
Nov 18 - Nov 19
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Everything was perfect!! I've stayed at this HoJo's before. The staff are great!! Clean breakfast area, very nice!!
Reviewed on Nov 8, 2025

Aloft Florence
820 WOODY JONES BOULEVARD, Florence, SC
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $104 total per night from Nov 18 to Nov 19
$104 total
Nov 18 - Nov 19
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Didn’t have breakfast but everything else was great
Reviewed on Nov 11, 2025

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2101 Florence Harllee Blvd, Florence, SC
Fully refundable
$107 nightly
The price is $120 total per night from Nov 16 to Nov 17
$120 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Room was clean and very comfortable I can’t wait to return this weekend but the only problem I had is the heater not working I was freezing in my room all night but I slept good though
Reviewed on Nov 3, 2025

La Quinta Inn & Suites by Wyndham Florence
2123 W Lucas St, Florence, SC
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $114 total per night from Nov 18 to Nov 19
$114 total
Nov 18 - Nov 19
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Yes - spotless- staff excellent
Reviewed on Nov 9, 2025

Microtel Inn & Suites by Wyndham Florence
1912 Enterprise Dr, Florence, SC
Fully refundableReserve now, pay when you stay
$54 nightly
The price is $60 total per night from Nov 16 to Nov 17
$60 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Great staff, nice rooms
Reviewed on Nov 8, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Pamplico with star-rating
Check Pamplico Hotels by Star Rating

3 Star Hotels
13 properties
Frequently asked questions
Recent Pamplico hotel reviews by fellow wanderers

Aloft Florence
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Didn’t have breakfast but everything else was great "
A verified traveler stayed at Aloft Florence
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