Book Hotels in Pamplico, SC
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Top Pamplico hotels

Comfort Inn & Suites
527 Woody Jones Blvd, Florence, SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $123 total per night from Jul 27 to Jul 28
$123 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
"one of the nicest comfort inns ive ever been to… bed was super comfortable"
Reviewed on Jul 11, 2025

Park Inn by Radisson Florence, SC
1729 Mandeville Road, Florence, SC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $111 total per night from Jul 13 to Jul 14
$111 total
Jul 13 - Jul 14
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. Enjoy ...
"Clean and comfortable."
Reviewed on Jul 9, 2025

Hyatt Place Florence Downtown
100 East Evans Street Florence, Florence, SC
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $116 total per night from Aug 4 to Aug 5
$116 total
Aug 4 - Aug 5
Total includes taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Nice and friendly faces 👌"
Reviewed on Jul 5, 2025

TownePlace Suites by Marriott Florence
2650 Hospitality Boulevard, Florence, SC
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $125 total per night from Jul 20 to Jul 21
$125 total
Jul 20 - Jul 21
Total includes taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"We really enjoyed our stay!"
Reviewed on Jul 6, 2025

Howard Johnson by Wyndham Florence
2038 W Lucas Street, I-95 Exit 164, Florence, SC
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Jul 13 to Jul 14
$79 total
Jul 13 - Jul 14
Total includes taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Clean, quiet and affordable
"Short one night stay. Room was clean and quiet."
Reviewed on Jul 10, 2025

La Quinta Inn & Suites by Wyndham Florence
2123 W Lucas St, Florence, SC
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $108 total per night from Aug 3 to Aug 4
$108 total
Aug 3 - Aug 4
Total includes taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Nicely updated. Bathroom has some mold around tub. Very quiet. Very helpful and friendly staff. Easy access from an to 95."
Reviewed on Jul 3, 2025

Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr, Florence, SC
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $101 total per night from Jul 20 to Jul 21
$101 total
Jul 20 - Jul 21
Total includes taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"More protein options at breakfast."
Reviewed on Jul 7, 2025

Days Inn by Wyndham Florence/I-95 North
2111 West Lucas St/I-95, I-95 & Hwy 52 Exit 164, Florence, SC
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $68 total per night from Jul 27 to Jul 28
$68 total
Jul 27 - Jul 28
Total includes taxes and fees
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this motel. Guests will appreciate free perks like on-the-go breakfast and ...
"Dated… but clean… could use a DEEP clean.. hair dryer must have been dropped and had a big piece missing. Someone could get hurt. Full breakfast was a joke… boiled eggs waffles…. But no water to drink… I felt safe so that’s a plus!"
Reviewed on Jul 7, 2025

Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr, Florence, SC
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $66 total per night from Jul 17 to Jul 18
$66 total
Jul 17 - Jul 18
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"I really like the location. It was close to the mall, Target, and many dining locations. The staff was so friendly and welcoming."
Reviewed on Jul 3, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Pamplico with star-rating
Check Pamplico Hotels by Star Rating

3 Star Hotels
12 properties
Frequently asked questions
Recent Pamplico hotel reviews by fellow wanderers

Comfort Inn & Suites
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"one of the nicest comfort inns ive ever been to… bed was super comfortable "
A verified traveler from Lansdale stayed at Comfort Inn & Suites
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