Book Hotels in Pamplico, SC

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Top Pamplico hotels

The Inn at the Crossroads

The Inn at the Crossroads

2 out of 5
128 West Main Street, Lake City, SC
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $145 total per night from Oct 13 to Oct 14
$145 total
Oct 13 - Oct 14
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Clean,easy parking,Comfy beds and friendly staff.Def recommend 10/10"

Reviewed on Sep 28, 2025

Opens in a new windowThe Inn at the Crossroads
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road, Florence, SC
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $106 total per night from Oct 5 to Oct 6
$106 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. Enjoy ...
"Conveniently located for stopover on a long journey. Giod parking soace and a friendly front desk staff."

Reviewed on Sep 25, 2025

Opens in a new windowPark Inn by Radisson Florence, SC
Comfort Inn & Suites

Comfort Inn & Suites

2.5 out of 5
527 Woody Jones Blvd, Florence, SC
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $107 total per night from Oct 5 to Oct 6
$107 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
"The staff at check in was very friendly and cheerful. Property is convenient to restaurants and is clean and quiet. Love the gnome decorations!"

Reviewed on Sep 24, 2025

Opens in a new windowComfort Inn & Suites
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence, Florence, SC
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $116 total per night from Oct 13 to Oct 14
$116 total
Oct 13 - Oct 14
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Stayed for 2 nights with my son for a tournament. Safe, clean, excellent location at the end of the street downtown so it was quiet at night. Yummy breakfast every morning. Convenient parking in lot across the street. Only qualm I had was our room wasn’t cleaned Saturday and when I inquired, I was ..."

Reviewed on Sep 26, 2025

Opens in a new windowHyatt Place Florence Downtown
TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

3 out of 5
2650 Hospitality Boulevard, Florence, SC
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $125 total per night from Oct 5 to Oct 6
$125 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Staff very friendly, welcoming and helpful. Room was excellent. Bed comfortable. Perfect location."

Reviewed on Sep 25, 2025

Opens in a new windowTownePlace Suites by Marriott Florence
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street, I-95 Exit 164, Florence, SC
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $73 total per night from Oct 1 to Oct 2
$73 total
Oct 1 - Oct 2
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Nice, clean room. Good water pressure in shower. Area around premises a little sketchy, but room was quiet and bed comfy. Check in was quick and front desk staff very nice and personable."

Reviewed on Sep 23, 2025

Opens in a new windowHoward Johnson by Wyndham Florence
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

3 out of 5
2123 W Lucas St, Florence, SC
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $116 total per night from Oct 6 to Oct 7
$116 total
Oct 6 - Oct 7
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Great location"

Reviewed on Sep 24, 2025

Opens in a new windowLa Quinta Inn & Suites by Wyndham Florence
Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North

2 out of 5
2111 West Lucas St/I-95, I-95 & Hwy 52 Exit 164, Florence, SC
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $72 total per night from Oct 6 to Oct 7
$72 total
Oct 6 - Oct 7
Total with taxes and fees
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this motel. Guests will appreciate free perks like on-the-go breakfast and ...
"I see some small bugs in the bathroom and the mirror frame is very dirty."

Reviewed on Sep 22, 2025

Opens in a new windowDays Inn by Wyndham Florence/I-95 North
Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence

2 out of 5
1912 Enterprise Dr, Florence, SC
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $62 total per night from Oct 5 to Oct 6
$62 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"The room was clean and comfortable. The breakfast was okay but had few options. Only 1 kind of mini muffins and limited cereal. My biggest issue is that they charged me for the room 2 times after I paid through Expedia. When I tried to explain to the manager, he blew me off, insisting he had refunded ..."

Reviewed on Sep 26, 2025

Opens in a new windowMicrotel Inn & Suites by Wyndham Florence
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Pamplico?
Family trips are where you make the best memories, but it's no secret that traveling with young ones can be daunting. These kid-friendly Pamplico hotels come with perks designed to keep travelers of all ages relaxed and happy: Your entourage will enjoy their time at Cheerful home with plenty of privacy and entertainment room.. A fireplace and free WiFi are just a couple of the things that help make this hotel a winner. The Inn at the Crossroads is another excellent choice. After an exciting day of exploring, return to your cozy room and amenities like complimentary breakfast and a pillowtop mattress.
Where can I find cheap hotels in Pamplico?
At Travelocity you'll find really nice hotels in Pamplico at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Pamplico rather than in Pamplico. We may find you even better rates, too.
How do I find the best Pamplico hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Pamplico then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Pamplico?
The cheapest hotel in Pamplico is $62. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Pamplico?
There are 136 hotels in Pamplico on Travelocity.
What are the best hotels in Pamplico?
Pamplico has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Pamplico for you!
When is the best time to visit Pamplico?
If you want the joy of a fun-filled trip in peak season, visit Pamplico during March, April and July. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, September and October.
When is the cheapest time to stay in Pamplico?
Based on historic data is usually the cheapest month to visit Pamplico. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Pamplico?
There are multiple hotels in Pamplico that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Pamplico. We have plenty of kid-friendly hotels in Pamplico to choose from on Travelocity!
Why book a hotel in Pamplico through Travelocity?
Because we have the top hotels in Pamplico! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Pamplico on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Pamplico hotel reviews by fellow wanderers

The Inn at the Crossroads

The Inn at the Crossroads

5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Clean,easy parking,Comfy beds and friendly staff.Def recommend 10/10"
A verified traveler stayed at The Inn at the Crossroads
The Inn at the Crossroads

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