Book Hotels in Pamplico, SC
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Top Pamplico hotels

Comfort Inn & Suites
527 Woody Jones Blvd, Florence, SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $123 total per night from Aug 10 to Aug 11
$123 total
Aug 10 - Aug 11
Total includes taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
"Everything was great. Nice and quiet and friendly staff."
Reviewed on Jul 21, 2025

Park Inn by Radisson Florence, SC
1729 Mandeville Road, Florence, SC
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $105 total per night from Aug 17 to Aug 18
$105 total
Aug 17 - Aug 18
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. Enjoy ...
"Overall it was good. Front desk staff were very friendly. The breakfast was good. It was disappointing that the light shade in the room was loose and there was a stain on the ceiling in the dining area, so maintenance was not done well."
Reviewed on Jul 21, 2025

Hyatt Place Florence Downtown
100 East Evans Street Florence, Florence, SC
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $116 total per night from Aug 4 to Aug 5
$116 total
Aug 4 - Aug 5
Total includes taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Would stay again
"Check in was fast and easy. The Hotel Lobby was clean and had a lounge and bar inside. We did not use the pool but there is one on the premises. The rooms were clean and well maintained. Bathroom was clean and fully stocked. Only thing I did not like was the parking. You have to drive down an alley ..."
Reviewed on Jul 21, 2025

TownePlace Suites by Marriott Florence
2650 Hospitality Boulevard, Florence, SC
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $125 total per night from Jul 27 to Jul 28
$125 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"thumbs up for pool, gym, laundry room, price!"
Reviewed on Jul 13, 2025

Howard Johnson by Wyndham Florence
2038 W Lucas Street, I-95 Exit 164, Florence, SC
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Jul 27 to Jul 28
$79 total
Jul 27 - Jul 28
Total includes taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Nice and close to the interstate. Very nice comfortable and clean room. The price was budget friendly"
Reviewed on Jul 22, 2025

La Quinta Inn & Suites by Wyndham Florence
2123 W Lucas St, Florence, SC
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $108 total per night from Aug 17 to Aug 18
$108 total
Aug 17 - Aug 18
Total includes taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Comfortable room. Breakfast ended at 9 and I thought it was 10. Beyond that everything was good"
Reviewed on Jul 19, 2025

Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr, Florence, SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $95 total per night from Aug 24 to Aug 25
$95 total
Aug 24 - Aug 25
Total includes taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Great place to rest and sleep after 11 hrs of driving."
Reviewed on Jul 20, 2025

Days Inn by Wyndham Florence/I-95 North
2111 West Lucas St/I-95, I-95 & Hwy 52 Exit 164, Florence, SC
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $68 total per night from Jul 29 to Jul 30
$68 total
Jul 29 - Jul 30
Total includes taxes and fees
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this motel. Guests will appreciate free perks like on-the-go breakfast and ...
"Dated… but clean… could use a DEEP clean.. hair dryer must have been dropped and had a big piece missing. Someone could get hurt. Full breakfast was a joke… boiled eggs waffles…. But no water to drink… I felt safe so that’s a plus!"
Reviewed on Jul 7, 2025

Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr, Florence, SC
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $71 total per night from Jul 27 to Jul 28
$71 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"I would reserve again, but my wife has her own opinion."
Reviewed on Jul 20, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Pamplico with star-rating
Check Pamplico Hotels by Star Rating

3 Star Hotels
12 properties
Frequently asked questions
Recent Pamplico hotel reviews by fellow wanderers

Comfort Inn & Suites
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Everything was great. Nice and quiet and friendly staff. "
A verified traveler stayed at Comfort Inn & Suites
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