Book Hotels in Pamplico, SC
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Top Pamplico hotels

Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
Fully refundable
$76 nightly
The price is $85 total per night from May 25 to May 26
$85 total
May 25 - May 26
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. Enjoy ...
The Park Inn is a perfectly acceptable place to overnight while on an I95 trip. The room was clean, the parking lot was safe and breakfast buffet was the familiar offering of eggs and waffles. The only drawback is the hotel feels dated and due for a renovation.
Reviewed on May 14, 2026

Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
Fully refundable
$110 nightly
The price is $123 total per night from May 24 to May 25
$123 total
May 24 - May 25
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
Staff very nice. Breakfast staff wass very nice. Plenty of parking.
Reviewed on May 14, 2026

Hyatt Place Florence Downtown
100 East Evans Street Florence Florence SC
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $137 total per night from May 25 to May 26
$137 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
From what I am used to to staying in the room was okay? It wasn’t nothing to write home about but it was 1000 better than the Hotel Blu in Myrtle Beach. Never Ever go there!!!! The staff were amazingly friendly they were the best part of the hotel. Breakfast was good I love a hotel with breakfast. ...
Reviewed on May 12, 2026

TownePlace Suites by Marriott Florence
2650 Hospitality Boulevard Florence SC
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $132 total per night from May 17 to May 18
$132 total
May 17 - May 18
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
When I went to take a shower my first day there where towels left behind the door from the last people that stayed in the room. I told the front desk about when I left for the day and asked if they would come and get them and they did not
Reviewed on May 14, 2026

Hampton Inn & Suites Florence-North-I-95
1735 Stokes Road Florence SC
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $129 total per night from May 25 to May 26
$129 total
May 25 - May 26
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Everything was great !
Reviewed on May 13, 2026

Fairfield Inn & Suites by Marriott Florence I-20
501 Woody Jones Boulevard Florence SC
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $142 total per night from May 18 to May 19
$142 total
May 18 - May 19
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the free continental ...
U changed me $160 and on check out gave me $114 rate. Something smells
Reviewed on May 12, 2026

Howard Johnson by Wyndham Florence
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $75 total per night from May 24 to May 25
$75 total
May 24 - May 25
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Clean comfortable and convenient. The staff was friendly, I could walk to the Starbucks and restaurants. The room was very clean. The bed was very comfortable. Great for this weary traveler.
Reviewed on May 14, 2026

Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $106 total per night from May 24 to May 25
$106 total
May 24 - May 25
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Best night’s sleep I’ve had in forever!! Very pleasant staff! Clean! Will definitely be making this our go to for our trips to Florida and back!!!
Reviewed on May 14, 2026

Spark by Hilton Florence North I-95, SC
1739 Mandeville Rd Florence SC
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $104 total per night from May 21 to May 22
$104 total
May 21 - May 22
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
This hotel is by far the BEST rooms are clean and comfortable staff are generous and the hotel itself is healthy and well kept update ☺️
Reviewed on May 14, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Pamplico with star-rating
Check Pamplico Hotels by Star Rating

3 Star Hotels
28 properties
Frequently asked questions
Recent Pamplico hotel reviews by fellow wanderers

Days Inn by Wyndham Florence Near Civic Center
5 out of 5
Posted 10 hours ago
Travelocity Verified Review
"Very clean and close to everything"
A verified traveler stayed at Days Inn by Wyndham Florence Near Civic Center
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