Book Hotels in Pamplico, SC

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Top Pamplico hotels

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $113 total per night from Dec 28 to Dec 29
$113 total
Dec 28 - Dec 29
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
The room was clean, the staff were friendly and the bed was the most comfortable I've had in a hotel in a long time. I appreciated the pet friendliness and the location is tucked away in a quiet area but close to I-95 with plenty of parking.

Reviewed on Dec 9, 2025

Opens in a new windowComfort Inn & Suites Florence Center Area
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $105 total per night from Dec 23 to Dec 24
$105 total
Dec 23 - Dec 24
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. Enjoy ...
Everything was okay except we were on the 2nd floor and the guest above us were heavy steppers and kept pacing. It was disturbing while trying to fall asleep. But the late check-out of 12 noon made up for it.

Reviewed on Dec 6, 2025

Opens in a new windowPark Inn by Radisson Florence, SC
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $112 total per night from Dec 15 to Dec 16
$112 total
Dec 15 - Dec 16
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Clean rooms, engaging and responsive staff, very pleasant and warm front desk attendant.

Reviewed on Dec 5, 2025

Opens in a new windowHyatt Place Florence Downtown
Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95

2.5 out of 5
1735 Stokes Road Florence SC
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $118 total per night from Dec 16 to Dec 17
$118 total
Dec 16 - Dec 17
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
The breakfast was great, the rooms were spectacular, the staff was wonderful. I would've gave it 5 stars, but one of the reasons why I picked this particular hotel was for the indoor pool and hot tub. But the hot tub was out of order. 😔😡 the pool wasn't heated, but the temperature wasn't bad

Reviewed on Dec 6, 2025

Opens in a new windowHampton Inn & Suites Florence-North-I-95
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $70 total per night from Dec 10 to Dec 11
$70 total
Dec 10 - Dec 11
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Ron was clean. Staff were professional

Reviewed on Dec 8, 2025

Opens in a new windowHoward Johnson by Wyndham Florence
Tru by Hilton Florence I-95

Tru by Hilton Florence I-95

2.5 out of 5
2140 West Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Dec 21 to Dec 22
$106 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Relax with a drink ...
room was great.clean and warm....staying with hiltons..Sandy our golden gives them 4 woofs...

Reviewed on Dec 7, 2025

Opens in a new windowTru by Hilton Florence I-95
Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC

3 out of 5
900 Woody Jones Blvd Florence SC
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $116 total per night from Dec 15 to Dec 16
$116 total
Dec 15 - Dec 16
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Nice and clean and spacious room. Friendly staff. My husband and kids likes the breakfast offerings.

Reviewed on Dec 1, 2025

Opens in a new windowHome2 Suites by Hilton Florence, SC
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

3 out of 5
2123 W Lucas St Florence SC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $111 total per night from Dec 23 to Dec 24
$111 total
Dec 23 - Dec 24
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Room was clean, staff was friendly

Reviewed on Dec 7, 2025

Opens in a new windowLa Quinta Inn & Suites by Wyndham Florence
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $90 total per night from Jan 7 to Jan 8
$90 total
Jan 7 - Jan 8, 2026
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
room was okay,

Reviewed on Dec 5, 2025

Opens in a new windowQuality Inn & Suites Florence Civic Center
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Pamplico?
Family trips are where you make the best memories, but it's no secret that traveling with young ones can be daunting. These kid-friendly Pamplico hotels come with perks designed to keep travelers of all ages relaxed and happy: Your entourage will enjoy their time at Cheerful home with plenty of privacy and entertainment room.. A fireplace and free WiFi are just a couple of the things that help make this hotel a winner. The Inn at the Crossroads is another excellent choice. After an exciting day of exploring, return to your cozy room and amenities like complimentary breakfast and a pillowtop mattress.
Where can I find cheap hotels in Pamplico?
At Travelocity you'll find really nice hotels in Pamplico at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Pamplico rather than in Pamplico. We may find you even better rates, too.
How do I find the best Pamplico hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Pamplico then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Pamplico?
The cheapest hotel in Pamplico is $70. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Pamplico?
There are 144 hotels in Pamplico on Travelocity.
What are the best hotels in Pamplico?
Pamplico has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Pamplico for you!
When is the best time to visit Pamplico?
If you want the joy of a fun-filled trip in peak season, visit Pamplico during March, April and July. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, September and October.
When is the cheapest time to stay in Pamplico?
Based on historic data is usually the cheapest month to visit Pamplico. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Pamplico?
There are multiple hotels in Pamplico that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Pamplico. We have plenty of kid-friendly hotels in Pamplico to choose from on Travelocity!
Why book a hotel in Pamplico through Travelocity?
Because we have the top hotels in Pamplico! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Pamplico on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Pamplico hotel reviews by fellow wanderers

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

5 out of 5
Posted 9 hours ago
Travelocity Verified Review
"The room was clean, the staff were friendly and the bed was the most comfortable I've had in a hotel in a long time. I appreciated the pet friendliness and the location is tucked away in a quiet area but close to I-95 with plenty of parking. "
A verified traveler stayed at Comfort Inn & Suites Florence Center Area
Comfort Inn & Suites Florence Center Area

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