Book Hotels in Pamplico, SC

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Top Pamplico hotels

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $107 total per night from Feb 1 to Feb 2
$107 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
Yes

Reviewed on Jan 24, 2026

Opens in a new windowComfort Inn & Suites Florence Center Area
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Fully refundable
$85 nightly
The price is $95 total per night from Feb 8 to Feb 9
$95 total
Feb 8 - Feb 9
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. Enjoy ...
Room was great. Could use some mold removal in the shower.

Reviewed on Jan 25, 2026

Opens in a new windowPark Inn by Radisson Florence, SC
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $112 total per night from Feb 2 to Feb 3
$112 total
Feb 2 - Feb 3
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
The room was clean and bed comfortable. Check in was good and staff helpful. My only complaint was in regard to a freezing rain storm that occurred overnight and it made walking to the designated parking area very treacherous. Customers walking to their cars were slipping and sliding as well as falling. ...

Reviewed on Jan 25, 2026

Opens in a new windowHyatt Place Florence Downtown
TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

3 out of 5
2650 Hospitality Boulevard Florence SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $123 total per night from Jan 29 to Jan 30
$123 total
Jan 29 - Jan 30
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Was clean and comfortable however charged us a $5.00 dollar parking fee. Really.

Reviewed on Jan 23, 2026

Opens in a new windowTownePlace Suites by Marriott Florence
Residence Inn Marriott Florence

Residence Inn Marriott Florence

3 out of 5
2660 Hospitality Blvd Florence SC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $111 total per night from Feb 1 to Feb 2
$111 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the free continental ...
Nice

Reviewed on Jan 23, 2026

Opens in a new windowResidence Inn Marriott Florence
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Jan 29 to Jan 30
$79 total
Jan 29 - Jan 30
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Every thing was great

Reviewed on Jan 25, 2026

Opens in a new windowHoward Johnson by Wyndham Florence
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

3 out of 5
2123 W Lucas St Florence SC
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $113 total per night from Feb 8 to Feb 9
$113 total
Feb 8 - Feb 9
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Clean rooms, friendly staff, great breakfast

Reviewed on Jan 25, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Florence
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$86 nightly
The price is $96 total per night from Feb 25 to Feb 26
$96 total
Feb 25 - Feb 26
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
I have to say it was all especially the staff very welcoming to us when we came when I came in room is very well clean. I will definitely stay again.

Reviewed on Jan 22, 2026

Opens in a new windowQuality Inn & Suites Florence Civic Center
Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North

2 out of 5
2111 West Lucas St/I-95 Florence SC
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $66 total per night from Jan 29 to Jan 30
$66 total
Jan 29 - Jan 30
Total with taxes and fees
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this motel. Guests will appreciate free perks like on-the-go breakfast and ...
Was ok can’t complain for the money.

Reviewed on Jan 26, 2026

Opens in a new windowDays Inn by Wyndham Florence/I-95 North
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Pamplico?
Family trips are where you make the best memories, but it's no secret that traveling with young ones can be daunting. These kid-friendly Pamplico hotels come with perks designed to keep travelers of all ages relaxed and happy: Your entourage will enjoy their time at Cheerful home with plenty of privacy and entertainment room.. A fireplace and free WiFi are just a couple of the things that help make this hotel a winner. The Inn at the Crossroads is another excellent choice. After an exciting day of exploring, return to your cozy room and amenities like complimentary breakfast and a pillowtop mattress.
Where can I find cheap hotels in Pamplico?
At Travelocity you'll find really nice hotels in Pamplico at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Pamplico rather than in Pamplico. We may find you even better rates, too.
How do I find the best Pamplico hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Pamplico then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Pamplico?
The cheapest hotel in Pamplico is $66. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Pamplico?
There are 149 hotels in Pamplico on Travelocity.
What are the best hotels in Pamplico?
Pamplico has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Pamplico for you!
When is the best time to visit Pamplico?
If you want the joy of a fun-filled trip in peak season, visit Pamplico during March, April and July. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, September and October.
When is the cheapest time to stay in Pamplico?
Based on historic data is usually the cheapest month to visit Pamplico. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Pamplico?
There are multiple hotels in Pamplico that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Pamplico. We have plenty of kid-friendly hotels in Pamplico to choose from on Travelocity!
Why book a hotel in Pamplico through Travelocity?
Because we have the top hotels in Pamplico! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Pamplico on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Pamplico hotel reviews by fellow wanderers

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Clean rooms, friendly staff, great breakfast "
A verified traveler stayed at La Quinta Inn & Suites by Wyndham Florence
La Quinta Inn & Suites by Wyndham Florence

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