Book Hotels in Pamplico, SC

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Top Pamplico hotels

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Fully refundable
$89 nightly
The price is $100 total per night from Sep 20 to Sep 21
$100 total
Sep 20 - Sep 21
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the free ...
"Loved our stay here. Best hotel I’ve stayed in in a long time. Going back next week on the way home."

Reviewed on Sep 12, 2026

Opens in a new windowPark Inn by Radisson Florence, SC
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
Fully refundable
$105 nightly
The price is $118 total per night from Oct 4 to Oct 5
$118 total
Oct 4 - Oct 5
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
"Second time we’ve stopped at this hotel overnight and both times was a pleasant experience. The hotel is clean and our bedroom was very comfortable. We didn’t have any issues during our visits. If I had to mention something less favorable, it would be the room carpet in a pet friendly hotel. But ..."

Reviewed on Sep 12, 2026

Opens in a new windowComfort Inn & Suites Florence Center Area
SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence

3 out of 5
2670 Hospitality Blvd Florence SC
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $122 total per night from Sep 20 to Sep 21
$122 total
Sep 20 - Sep 21
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the free continental ...
"We had a problem with a TV and refrigerator in one of our two rooms. The staff was excellent and replaced the items immediately so that the rest of our stay was good. The housekeeping staff was great. The desk staff and maintenance were great. The breakfast had a good selection and was good. There ..."

Reviewed on Sep 8, 2026

Opens in a new windowSpringHill Suites by Marriott Florence
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd Florence SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $95 total per night from Oct 4 to Oct 5
$95 total
Oct 4 - Oct 5
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Good value for quick stop on Florence, SC"

Reviewed on Sep 10, 2026

Opens in a new windowSpark by Hilton Florence North I-95, SC
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $72 total per night from Sep 20 to Sep 21
$72 total
Sep 20 - Sep 21
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"The facility looked run down. Got in the room and was not clean the curtain was falling down. The floors LVP flooring was curling up the paint on the back of the bathroom door was peeling off and the door would not close properly. The TV channels where all in spanish had to get that fixed as well. ..."

Reviewed on Sep 10, 2026

Opens in a new windowDays Inn by Wyndham Florence Near Civic Center
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $100 total per night from Sep 20 to Sep 21
$100 total
Sep 20 - Sep 21
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Opens in a new windowQuality Inn & Suites Florence Civic Center
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $72 total per night from Sep 13 to Sep 14
$72 total
Sep 13 - Sep 14
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Opens in a new windowHoward Johnson by Wyndham Florence
The Inn at the Crossroads

The Inn at the Crossroads

2 out of 5
128 West Main Street Lake City SC
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $103 total per night from Oct 13 to Oct 14
$103 total
Oct 13 - Oct 14
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Opens in a new windowThe Inn at the Crossroads
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $123 total per night from Oct 1 to Oct 2
$123 total
Oct 1 - Oct 2
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Opens in a new windowHyatt Place Florence Downtown
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Pamplico?
Family trips are where you make the best memories, but it's no secret that traveling with young ones can be daunting. These kid-friendly Pamplico hotels come with perks designed to keep travelers of all ages relaxed and happy: Your entourage will enjoy their time at Cheerful home with plenty of privacy and entertainment room.. A fireplace and free WiFi are just a couple of the things that help make this hotel a winner. The Inn at the Crossroads is another excellent choice. After an exciting day of exploring, return to your cozy room and amenities like complimentary breakfast and a pillowtop mattress.
Where can I find cheap hotels in Pamplico?
At Travelocity you'll find really nice hotels in Pamplico at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Pamplico rather than in Pamplico. We may find you even better rates, too.
How do I find the best Pamplico hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Pamplico then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Pamplico?
The cheapest hotel in Pamplico is $72. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Pamplico?
There are 168 hotels in Pamplico on Travelocity.
What are the best hotels in Pamplico?
Pamplico has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Pamplico for you!
When is the best time to visit Pamplico?
If you want the joy of a fun-filled trip in peak season, visit Pamplico during March, April and July. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, September and October.
When is the cheapest time to stay in Pamplico?
Based on historic data is usually the cheapest month to visit Pamplico. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Pamplico?
There are multiple hotels in Pamplico that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Pamplico. We have plenty of kid-friendly hotels in Pamplico to choose from on Travelocity!
Why book a hotel in Pamplico through Travelocity?
Because we have the top hotels in Pamplico! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Pamplico on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Pamplico hotel reviews by fellow wanderers

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Second time we’ve stopped at this hotel overnight and both times was a pleasant experience. The hotel is clean and our bedroom was very comfortable. We didn’t have any issues during our visits. If I had to mention something less favorable, it would be the room carpet in a pet friendly hotel. But that’s not a big issue for us. The staff here are wonderful, had a great conversation with the morning breakfast crew during our first visit. You can really feel the southern hospitality. We will be back when we’re in the area again."
A verified traveler stayed at Comfort Inn & Suites Florence Center Area
Comfort Inn & Suites Florence Center Area

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