Cheap Flights to Florence from $342
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How Much Does it Cost To Fly To Florence?
The cheapest prices found with in the last 7 days for return flights were $384 and $342 for one-way flights to Florence for the period specified. Prices and availability are subject to change. Additional terms apply
LGA
LaGuardia
FLO
Florence Regional
$440 Roundtrip, just found
$440
Roundtrip
just found
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| DEN | Florence | November 3 to November 11 | $384 |
| BOS | Florence | October 17 to October 31 | $490 |
| TPA | Florence | October 10 to October 12 | $498 |
| LGA | Florence | October 15 to October 18 | $504 |
| EWR | Florence | October 15 to October 18 | $504 |
| EWR | Florence | October 15 to October 18 | $504 |
| MSP | Florence | October 15 to October 17 | $525 |
Florence Flight Information
Traveling to | Florence |
|---|---|
Lowest Price | $384 |
Number of Airlines Serving | |
Airlines Serving | American Airlines |
Number of Daily Flights | |
Airlines with Direct Flights |
Find The Perfect Hotel For After Your Flight
Amazing Florence Accommodation Deals
Red Roof Inn Florence - Civic Center
2690 David H McLeod Boulevard Florence SC
$61 nightly
The price is $68 total per night from Sep 16 to Sep 17
$68 total
Sep 16 - Sep 17
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.8/10 (1,002 reviews)
"Upon entering room, smelled musty. No breakfast."
Reviewed on Sep 12, 2026
Budget Inn Timmonsville
2200 Cale Yarborough Highway Timmonsville SC
$61 nightly
The price is $68 total per night from Sep 14 to Sep 15
$68 total
Sep 14 - Sep 15
Total with taxes and fees
Stay at this motel in Timmonsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Florence Motor Speedway is located nearby.
7/10 Good! (350 reviews)
"It was good for the price."
Reviewed on Sep 12, 2026
Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr Florence SC
$64 nightly
The price is $72 total per night from Sep 28 to Sep 29
$72 total
Sep 28 - Sep 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,005 reviews)
"The facility looked run down. Got in the room and was not clean the curtain was falling down. The floors LVP flooring was curling up the paint on the back of the bathroom door was peeling off and the door would not close properly. The TV channels where all in spanish had to get that fixed as well. ..."
Reviewed on Sep 10, 2026
Save an average of 15% on thousands of hotels when you're signed in
Spark by Hilton Florence North I-95, SC
1739 Mandeville Rd Florence SC
$85 nightly
The price is $95 total per night from Oct 4 to Oct 5
$95 total
Oct 4 - Oct 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (290 reviews)
"Good value for quick stop on Florence, SC"
Reviewed on Sep 10, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Luxury Hotels in Florence
The Mantissa Hotel
130 East Carolina Ave Hartsville SC
$180 nightly
The price is $202 total per night from Sep 24 to Sep 25
$202 total
Sep 24 - Sep 25
Total with taxes and fees
Stay at this hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
Days Inn by Wyndham Dillon
823 Radford Blvd Dillon SC
$60 nightly
The price is $67 total per night from Oct 1 to Oct 2
$67 total
Oct 1 - Oct 2
Total with taxes and fees
Stay at this hotel in Dillon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Hotel Florence, Tapestry Collection by Hilton
126 W Evans St Florence SC
$139 nightly
The price is $155 total per night from Sep 20 to Sep 21
$155 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (654 reviews)
"I stay every year because the rooms are always clean and the beds really comfortable. Wondering when they are going to replace the stinky hall carpeting downstairs. It has been smelly for a few years and they keep trying to clean it or cover the smell. It’s not working. Staff is wonderful."
Reviewed on Sep 11, 2026
Save an average of 15% on thousands of hotels when you're signed in
Days Inn by Wyndham Florence/I-95 North
2111 West Lucas St/I-95 Florence SC
$59 nightly
The price is $66 total per night from Sep 20 to Sep 21
$66 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.6/10 (1,002 reviews)
"The constant smell of smoke in the room and"
Reviewed on Sep 12, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Florence
Home2 Suites by Hilton Florence, SC
900 Woody Jones Blvd Florence SC
$106 nightly
The price is $119 total per night from Sep 27 to Sep 28
$119 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,000 reviews)
"Wonderful hotel with plenty of parking. Clean rooms and quiet atmosphere. Friendly staff as well."
Reviewed on Sep 10, 2026
Spark by Hilton Florence North I-95, SC
1739 Mandeville Rd Florence SC
$85 nightly
The price is $95 total per night from Oct 4 to Oct 5
$95 total
Oct 4 - Oct 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (290 reviews)
"Good value for quick stop on Florence, SC"
Reviewed on Sep 10, 2026
Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr Florence SC
$64 nightly
The price is $72 total per night from Sep 28 to Sep 29
$72 total
Sep 28 - Sep 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,005 reviews)
"The facility looked run down. Got in the room and was not clean the curtain was falling down. The floors LVP flooring was curling up the paint on the back of the bathroom door was peeling off and the door would not close properly. The TV channels where all in spanish had to get that fixed as well. ..."
Reviewed on Sep 10, 2026
Save an average of 15% on thousands of hotels when you're signed in
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
3440 W Radio Dr Florence SC
$119 nightly
The price is $133 total per night from Oct 11 to Oct 12
$133 total
Oct 11 - Oct 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,004 reviews)
"The room was clean and comfortable. The breakfast was hot and plentiful. We would stay here again."
Reviewed on Sep 13, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Need a Car For After Your Flight?
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Plane Tickets To Florence
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