Cheap Flights to Florence from $294
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How Much Does it Cost To Fly To Florence?
The cheapest prices found with in the last 7 days for return flights were $339 and $294 for one-way flights to Florence for the period specified. Prices and availability are subject to change. Additional terms apply
DSM
Des Moines Intl.
FLO
Florence Regional
$535 Roundtrip, found 1 day ago
$535
Roundtrip
found 1 day ago
Florence Flight Information
Traveling to | Florence |
|---|---|
Lowest Price | $339 |
Number of Airlines Serving | |
Airlines Serving | American Airlines |
Number of Daily Flights | |
Airlines with Direct Flights |
Find The Perfect Hotel For After Your Flight
Amazing Florence Accommodation Deals
Red Roof Inn Florence - Civic Center
2690 David H McLeod Boulevard Florence SC
$56 nightly
The price is $63 total per night from Sep 1 to Sep 2
$63 total
Sep 1 - Sep 2
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.8/10 (1,006 reviews)
"I booked three rooms and all three rooms were extremely dirty, there were holes in the walls, mold growing on the ceilings, dead roaches in the light,the room smelled like dog pee and cigarettes, urine stains on the walls in the bathrooms, the light above the sink didn't work, the toilet was leaking, ..."
Reviewed on Aug 3, 2026
Budget Inn Timmonsville
2200 Cale Yarborough Highway Timmonsville SC
$61 nightly
The price is $68 total per night from Aug 9 to Aug 10
$68 total
Aug 9 - Aug 10
Total with taxes and fees
Stay at this motel in Timmonsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Florence Motor Speedway is located nearby.
7/10 Good! (348 reviews)
"I booked to crash for the night and keep getting to my destination. But there is no reception, everything is through the window. Entire reception is filled with boxes, mentioned complimentary breakfast, but when I checked in, I understood nothing will be as I expected. TV, Microwave, Fridge didnt ..."
Reviewed on Aug 7, 2026
Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr Florence SC
$64 nightly
The price is $72 total per night from Aug 9 to Aug 10
$72 total
Aug 9 - Aug 10
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Save an average of 15% on thousands of hotels when you're signed in
Spark by Hilton Florence North I-95, SC
1739 Mandeville Rd Florence SC
$93 nightly
The price is $104 total per night from Aug 16 to Aug 17
$104 total
Aug 16 - Aug 17
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (251 reviews)
"Vlea"
Reviewed on Aug 7, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Luxury Hotels in Florence
The Mantissa Hotel
130 East Carolina Ave Hartsville SC
$180 nightly
The price is $202 total per night from Aug 16 to Aug 17
$202 total
Aug 16 - Aug 17
Total with taxes and fees
Stay at this hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (300 reviews)
"The staff and the place was amazing. Although it’s a small town , there was plenty to do. Everyone I met there made my family and I feel like there family. We will definitely stay here again."
Reviewed on Aug 3, 2026
Days Inn by Wyndham Dillon
823 Radford Blvd Dillon SC
$62 nightly
The price is $70 total per night from Sep 1 to Sep 2
$70 total
Sep 1 - Sep 2
Total with taxes and fees
Stay at this hotel in Dillon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Hotel Florence, Tapestry Collection by Hilton
126 W Evans St Florence SC
$139 nightly
The price is $155 total per night from Aug 15 to Aug 16
$155 total
Aug 15 - Aug 16
Total with taxes and fees
Book a stay at this spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (649 reviews)
"Amazing location and Monica at the front desk is a doll!"
Reviewed on Jul 29, 2026
Save an average of 15% on thousands of hotels when you're signed in
Days Inn by Wyndham Florence/I-95 North
2111 West Lucas St/I-95 Florence SC
$53 nightly
The price is $59 total per night from Aug 30 to Aug 31
$59 total
Aug 30 - Aug 31
Total with taxes and fees
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.6/10 (1,003 reviews)
"This is a mixed review as the hotel was under renovations when we went there and we needed up cancelling our reservation once we arrived. The lobby/ buffet area had stacks of paint cans, and smelled of chemicals. I went to check out our non-smoking room, and the neighbor was sitting in the doorway ..."
Reviewed on Aug 8, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Florence
Home2 Suites by Hilton Florence, SC
900 Woody Jones Blvd Florence SC
$102 nightly
The price is $114 total per night from Aug 23 to Aug 24
$114 total
Aug 23 - Aug 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,002 reviews)
"Overall, we had a good stay at Home2 Suites in Florence, SC. The hotel was clean, the staff was friendly and welcoming, and the room was comfortable. The bathroom could definitely use some renovation, but it was clean and functional. The complimentary breakfast was the biggest disappointment. Compared ..."
Reviewed on Aug 5, 2026
Spark by Hilton Florence North I-95, SC
1739 Mandeville Rd Florence SC
$93 nightly
The price is $104 total per night from Aug 16 to Aug 17
$104 total
Aug 16 - Aug 17
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (251 reviews)
"Vlea"
Reviewed on Aug 7, 2026
Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr Florence SC
$64 nightly
The price is $72 total per night from Aug 9 to Aug 10
$72 total
Aug 9 - Aug 10
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Save an average of 15% on thousands of hotels when you're signed in
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
3440 W Radio Dr Florence SC
$114 nightly
The price is $128 total per night from Aug 16 to Aug 17
$128 total
Aug 16 - Aug 17
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,004 reviews)
"Did not like that the check in is at 4pm had to wait a whole hour"
Reviewed on Aug 4, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Need a Car For After Your Flight?
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Plane Tickets To Florence
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