Cheap Flights to Florence from $317

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How Much Does it Cost To Fly To Florence?

The cheapest prices found with in the last 7 days for return flights were $325 and $317 for one-way flights to Florence for the period specified. Prices and availability are subject to change. Additional terms apply

OriginDestinationTravel DatesFlights From*
MSPFlorenceMarch 23 to March 28$325
DENFlorenceFebruary 28 to March 3$703
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
DENFlorenceFebruary 28 to March 3$703
*Prices include taxes and fees

Florence Flight Information

Traveling to
Florence
Lowest Price
$325
Number of Airlines Serving
Airlines Serving
American Airlines
Number of Daily Flights
Airlines with Direct Flights

Find The Perfect Hotel For After Your Flight

Amazing Florence Accommodation Deals

Red Roof Inn Florence - Civic Center

Red Roof Inn Florence - Civic Center

2 out of 5
2690 David H McLeod Boulevard Florence SC
$56 nightly
The price is $63 total per night from Feb 24 to Feb 25
$63 total
Feb 24 - Feb 25
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.8/10 (1,001 reviews)
I didn't like the $50.00 Deposit at the desk when I was Quoted one Specific Price

Reviewed on Feb 16, 2026

Opens in a new windowRed Roof Inn Florence - Civic Center
Budget Inn Timmonsville

Budget Inn Timmonsville

2 out of 5
2200 Cale Yarborough Highway Timmonsville SC
$61 nightly
The price is $68 total per night from Feb 22 to Feb 23
$68 total
Feb 22 - Feb 23
Total with taxes and fees
Stay at this motel in Timmonsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Florence Motor Speedway is located nearby.
7/10 Good! (327 reviews)
Clean and comfortable bed for this price range. Easy to walk pets.

Reviewed on Feb 20, 2026

Opens in a new windowBudget Inn Timmonsville
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
$67 nightly
The price is $75 total per night from Feb 22 to Feb 23
$75 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,007 reviews)
Great room and service

Reviewed on Feb 18, 2026

Opens in a new windowDays Inn by Wyndham Florence Near Civic Center
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Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd Florence SC
$97 nightly
The price is $108 total per night from Feb 24 to Feb 25
$108 total
Feb 24 - Feb 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Opens in a new windowSpark by Hilton Florence North I-95, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Florence

The Mantissa Hotel

The Mantissa Hotel

3 out of 5
130 East Carolina Ave Hartsville SC
$104 nightly
The price is $116 total per night from Mar 14 to Mar 15
$116 total
Mar 14 - Mar 15
Total with taxes and fees
Stay at this hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (274 reviews)
This was an outstanding hotel We will stay again when in town

Reviewed on Jan 18, 2026

Opens in a new windowThe Mantissa Hotel
Days Inn by Wyndham Dillon

Days Inn by Wyndham Dillon

2 out of 5
823 Radford Blvd Dillon SC
$55 nightly
The price is $62 total per night from Mar 1 to Mar 2
$62 total
Mar 1 - Mar 2
Total with taxes and fees
Stay at this hotel in Dillon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
5.4/10 (875 reviews)
They canceled our reservation 30 minutes before we got there. Supposedly because of an incident there.

Reviewed on Jan 9, 2026

Opens in a new windowDays Inn by Wyndham Dillon
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

3 out of 5
126 W Evans St Florence SC
$130 nightly
The price is $146 total per night from Mar 1 to Mar 2
$146 total
Mar 1 - Mar 2
Total with taxes and fees
Book a stay at this spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (619 reviews)
I like to support these old hotels, but when their owner does not keep them up there is no reason for me to support them. No one at the desk to check in meant a 10 min wait for someone. A very small room with no closet at all. None. Tried to eat bfast there, but couldn't not get a menu. Got some ...

Reviewed on Feb 18, 2026

Opens in a new windowHotel Florence, Tapestry Collection by Hilton
Save an average of 15% on thousands of hotels when you're signed in
Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North

2 out of 5
2111 West Lucas St/I-95 Florence SC
$63 nightly
The price is $71 total per night from Feb 23 to Feb 24
$71 total
Feb 23 - Feb 24
Total with taxes and fees
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,001 reviews)
Room was filthy. Economical hotel but no reason for dirty floors, bathroom. Hair in toilet, tub, & floor. Found old piece of candy next to chair, floor had not been swept or cleaned it looked like in a very long time. Stains on the bed covers, Very dirty- to late to find someplace else - slept on ...

Reviewed on Feb 21, 2026

Opens in a new windowDays Inn by Wyndham Florence/I-95 North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Florence

Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC

3 out of 5
900 Woody Jones Blvd Florence SC
$106 nightly
The price is $119 total per night from Mar 8 to Mar 9
$119 total
Mar 8 - Mar 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,003 reviews)
The room was clean

Reviewed on Feb 16, 2026

Opens in a new windowHome2 Suites by Hilton Florence, SC
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd Florence SC
$97 nightly
The price is $108 total per night from Feb 24 to Feb 25
$108 total
Feb 24 - Feb 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Opens in a new windowSpark by Hilton Florence North I-95, SC
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
$67 nightly
The price is $75 total per night from Feb 22 to Feb 23
$75 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,007 reviews)
Great room and service

Reviewed on Feb 18, 2026

Opens in a new windowDays Inn by Wyndham Florence Near Civic Center
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Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

2.5 out of 5
3440 W Radio Dr Florence SC
$111 nightly
The price is $125 total per night from Feb 23 to Feb 24
$125 total
Feb 23 - Feb 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,001 reviews)
Clean & very friendly stafg

Reviewed on Feb 21, 2026

Opens in a new windowHoliday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Best Florence Flight and Hotel Packages

Florence flight + hotel packages - economy flights

Price found within the past 48 hours. Click for updated prices.
Affordable Suites Florence
Baymont by Wyndham Cheraw
Fairfield Inn by Marriott Hartsville
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Lowest prices found within the past 11 hours. Prices and availability subject to change. Additional terms may apply.

Plane Tickets To Florence

Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Florence. Browse through our inventory to explore a wide range of cheap flights to Florence to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Florence as you anxiously await to exit the plane and explore what Florence has to offer. Considering all the amazing local food and culture in Florence, we won't hold this against you.

When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Florence to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Florence without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Florence with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Florence today!

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*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.