Explore 12 Luxury Hotels in Florence
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Best Luxury Hotels in Florence
Hotel Florence, Tapestry Collection by Hilton
126 W Evans St Florence SC
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $155 total per night from Nov 14 to Nov 15
$155 total
Nov 14 - Nov 15
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
8.8/10 Excellent! (658 reviews)
"The staff were great!! Parking was close by and easy. The restaurant bar was a great stop. If you want a refrigerator in your room you need to ask prior to arrival."
Reviewed on Oct 10, 2026
Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $77 total per night from Oct 28 to Oct 29
$77 total
Oct 28 - Oct 29
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
7.2/10 Good! (1,004 reviews)
"The bed was hard as a brick"
Reviewed on Oct 27, 2026
Quality Inn Dillon
817 Radford Blvd Dillon SC
Fully refundable
$90 nightly
The price is $101 total per night from Nov 1 to Nov 2
$101 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the express ...
7.2/10 Good! (853 reviews)
"Good and well maintained!"
Reviewed on Oct 19, 2026
Red Roof Inn Florence - Civic Center
2690 David H McLeod Boulevard Florence SC
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $66 total per night from Oct 28 to Oct 29
$66 total
Oct 28 - Oct 29
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...
6.8/10 (1,000 reviews)
"Don't stay here...enough said"
Reviewed on Oct 19, 2026
Days Inn by Wyndham Florence/I-95 North
2111 West Lucas St/I-95 Florence SC
Fully refundableReserve now, pay when you stay
$54 nightly
The price is $61 total per night from Nov 13 to Nov 14
$61 total
Nov 13 - Nov 14
Total with taxes and fees
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this motel. Guests will appreciate free perks like continental breakfast and ...
6.6/10 (1,003 reviews)
"Excelente"
Reviewed on Oct 26, 2026
Days Inn by Wyndham Dillon
823 Radford Blvd Dillon SC
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $68 total per night from Nov 2 to Nov 3
$68 total
Nov 2 - Nov 3
Total with taxes and fees
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like on-the-go breakfast and ...
5.4/10 (937 reviews)
"Food left in micro from previous guest, hairdryer doesn't work, no directions for TV when you call front desk no one answers breakfast bar consists of fruit loops or a waffle. Better choices for less or same money wyndham has really gone down."
Reviewed on Oct 8, 2026
Clarion Inn & Suites Florence - Darlington
1819 West Lucas Street Florence SC
Fully refundable
$50 nightly
The price is $56 total per night from Nov 27 to Nov 28
$56 total
Nov 27 - Nov 28
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Enjoy the seasonal outdoor pool and free perks like on-the-go breakfast and free self parking. A business ...
4.6/10 (372 reviews)
"The bathroom ceiling paint was peeling so bad some paint fell on my head. The bathtub was also chipped and peeling. Thought Clarion was better than this! Will be sending pictures to corporate. And it wasn’t even 30% full so maybe this was better than other rooms."
Reviewed on Oct 25, 2026
The Mantissa Hotel
130 East Carolina Ave Hartsville SC
Fully refundableReserve now, pay when you stay
$180 nightly
The price is $202 total per night from Nov 2 to Nov 3
$202 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Enjoy the a rooftop terrace and free perks like on-the-go breakfast and free self parking. A business ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Florence Luxury Hotels
Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Florence luxury hotels are the plush oasis you’ve been looking for.
Choose from the best luxury hotels in Florence to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.
We want you to enjoy your next vacation in style and the top luxury resorts in Florence will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Florence, and plan your next opulent escape.
Florence hotels essential information
Accommodation | 422 hotels |
|---|---|
Lowest Price | $56 |
Highest Price | $202 |
Popular hotels | The Mantissa Hotel, Days Inn by Wyndham Dillon, Hotel Florence, Tapestry Collection by Hilton, Days Inn by Wyndham Florence/I-95 North, Clarion Inn & Suites Florence - Darlington, Red Roof Inn Florence - Civic Center, Days Inn by Wyndham Florence Near Civic Center, Quality Inn Dillon |
Popular Luxury Stays in Florence
Recent Florence Hotel Reviews By Fellow Wanderers
Quality Inn & Suites Florence Civic Center
4 out of 5
Posted 2 days ago
Travelocity Verified Review
"Room was newly renovated and that was great however, musty smell made it seem not as clean. Some other housekeeping items, bathroom could’ve been cleaner, mirrors not wiped down properly showing signs of prior use, open soap left on the counter. Small signs like this made the room appear not as clean as the renovated furniture may have indicated. Staff was nice and friendly, parking lot well lit, room was easy to reach from the parking space. And overall location not far from the highway which was convenient."
A verified traveler stayed at Quality Inn & Suites Florence Civic Center
Days Inn by Wyndham Florence Near Civic Center
4 out of 5
Posted 6 days ago
Travelocity Verified Review
"Room was great, but the complimentary breakfast was very poor."
A verified traveler stayed at Days Inn by Wyndham Florence Near Civic Center