Explore 12 Luxury Hotels in Florence
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Best Luxury Hotels in Florence
The Mantissa Hotel
130 East Carolina Ave Hartsville SC
Fully refundableReserve now, pay when you stay
$171 nightly
The price is $192 total per night from Aug 28 to Aug 29
$192 total
Aug 28 - Aug 29
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Enjoy the a rooftop terrace and free perks like on-the-go breakfast and free self parking. A business ...
9.2/10 Wonderful! (298 reviews)
"Always so inviting and welcoming"
Reviewed on Jul 28, 2026
Hotel Florence, Tapestry Collection by Hilton
126 W Evans St Florence SC
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $155 total per night from Aug 7 to Aug 8
$155 total
Aug 7 - Aug 8
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
8.8/10 Excellent! (647 reviews)
"See my last review. All the same great things about it are still true. It's a Tapestry Hilton Rez system hotel, and they exceed the standards nicely. Parking free on downtown all-renovated preservation properties with terrific shopping as well. Plenty of on street protected checkin and check out ..."
Reviewed on Jul 24, 2026
Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $72 total per night from Aug 2 to Aug 3
$72 total
Aug 2 - Aug 3
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
7.2/10 Good! (1,008 reviews)
"I was told at check-in that there is a national towel shortage and asked if I would be needing any during my stay. I told them I would. They also do not offer housekeeping services. Room was clean upon arrival, but pretty sure floors haven't been mopped in a while because the bottom of my feet quickly ..."
Reviewed on Jul 28, 2026
Quality Inn Dillon
817 Radford Blvd Dillon SC
Fully refundable
$86 nightly
The price is $96 total per night from Aug 9 to Aug 10
$96 total
Aug 9 - Aug 10
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the express ...
7.2/10 Good! (830 reviews)
"Bathroom and vanity areas clean and ready for use, stocked with toilet tissue, facial tissue, towels, washcloths. Bathroom and bed linens clean and smelled freshly laundered. *thumbs up* Had cable TV channels! Yay! Mini fridge! Room was carpeted. Carpet was smelly and sticky. Pull-out couch still ..."
Reviewed on Jul 25, 2026
Red Roof Inn Florence - Civic Center
2690 David H McLeod Boulevard Florence SC
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $66 total per night from Jul 29 to Jul 30
$66 total
Jul 29 - Jul 30
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...
6.8/10 (1,002 reviews)
"Average hotel. A bed to sleep in while taking a break from traveling."
Reviewed on Jul 25, 2026
Days Inn by Wyndham Florence/I-95 North
2111 West Lucas St/I-95 Florence SC
Fully refundableReserve now, pay when you stay
$52 nightly
The price is $58 total per night from Aug 13 to Aug 14
$58 total
Aug 13 - Aug 14
Total with taxes and fees
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this motel. Guests will appreciate free perks like on-the-go breakfast and ...
6.6/10 (1,004 reviews)
"Holes in the wall, flies in the room, floors dirty, couch dirty. Don’t bother, too many other options nearby."
Reviewed on Jul 27, 2026
Days Inn by Wyndham Dillon
823 Radford Blvd Dillon SC
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $70 total per night from Aug 2 to Aug 3
$70 total
Aug 2 - Aug 3
Total with taxes and fees
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like on-the-go breakfast and ...
5.4/10 (913 reviews)
"I booked a non-smoking room, but there was a noticeable smoke smell in the room. The breakfast was also very disappointing and lacked even basic items like coffee. Overall, I would not recommend this hotel."
Reviewed on Jul 26, 2026
Clarion Inn & Suites Florence - Darlington
1819 West Lucas Street Florence SC
Fully refundable
$54 nightly
The price is $60 total per night from Aug 14 to Aug 15
$60 total
Aug 14 - Aug 15
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Enjoy the seasonal outdoor pool and free perks like on-the-go breakfast and free self parking. A business ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Florence Luxury Hotels
Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Florence luxury hotels are the plush oasis you’ve been looking for.
Choose from the best luxury hotels in Florence to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.
We want you to enjoy your next vacation in style and the top luxury resorts in Florence will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Florence, and plan your next opulent escape.
Florence hotels essential information
Accommodation | 417 hotels |
|---|---|
Lowest Price | $58 |
Highest Price | $192 |
Popular hotels | The Mantissa Hotel, Days Inn by Wyndham Dillon, Hotel Florence, Tapestry Collection by Hilton, Days Inn by Wyndham Florence/I-95 North, Clarion Inn & Suites Florence - Darlington, Red Roof Inn Florence - Civic Center, Days Inn by Wyndham Florence Near Civic Center, Quality Inn Dillon |
Popular Luxury Stays in Florence
Recent Florence Hotel Reviews By Fellow Wanderers
Quality Inn & Suites Florence Civic Center
4 out of 5
Posted 1 hour ago
Travelocity Verified Review
"We stay overnight. Quick stop on our way to Maryland and simply wanted a clean safe place to spend the night, at a reasonable cost. Quality in provided both. The ladies at the front desk were super friendly and helpful. The room had been renovated and we were very comfortable. I loved the powerful hairdryer!!! It wasn’t the small; powerless ones they usually have, that are attached to the wall. If you have long thick hair like I do, you understand💜 The only issue we had was with the breakfast. Everything was set up neatly and clean but they really stuck to “continental breakfast”, the selection wasn’t much at all."
A verified traveler stayed at Quality Inn & Suites Florence Civic Center