Explore 12 Luxury Hotels in Florence
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Best Luxury Hotels in Florence
The Mantissa Hotel
130 East Carolina Ave Hartsville SC
Fully refundableReserve now, pay when you stay
$180 nightly
The price is $202 total per night from May 4 to May 5
$202 total
May 4 - May 5
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Enjoy the a rooftop terrace and free perks like on-the-go breakfast and free self parking. A business ...
9.2/10 Wonderful! (285 reviews)
This hotel was truly a gem. I was so surprised to see the size of the room and the suite amenities . The linens and bedding were super nice and clean. The living space was large and had the feeling of being at home. A cute Boutique surprise when I walked into the room. Highly recommend!!
Reviewed on Apr 10, 2026
Hotel Florence, Tapestry Collection by Hilton
126 W Evans St Florence SC
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $146 total per night from May 7 to May 8
$146 total
May 7 - May 8
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
8.8/10 Excellent! (631 reviews)
I did not stay for breakfast
Reviewed on Apr 27, 2026
Quality Inn Dillon
817 Radford Blvd Dillon SC
Fully refundable
$82 nightly
The price is $91 total per night from May 27 to May 28
$91 total
May 27 - May 28
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the express ...
7.2/10 Good! (801 reviews)
We were in Atlanta to see a Braves game and hotel was conveniently located 15 minutes from Truist Park. Clean, spacious room with a Keurig coffee pot. :)
Reviewed on Apr 27, 2026
Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $74 total per night from Apr 29 to Apr 30
$74 total
Apr 29 - Apr 30
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
7/10 Good! (1,010 reviews)
Not much of a breakfast, unless you like waffles! This is a hotel that was recently renovated with the intention of making it a two star hotel, which it is. We paid two star rates, so no complaints there. Friendly staff, WiFi, TV were fine. Backlight on the bathroom mirror was flickering, not a very ...
Reviewed on Apr 27, 2026
Red Roof Inn Florence - Civic Center
2690 David H McLeod Boulevard Florence SC
Fully refundableReserve now, pay when you stay
$56 nightly
The price is $63 total per night from May 4 to May 5
$63 total
May 4 - May 5
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...
6.8/10 (1,002 reviews)
It does the job. Clean bed and bathroom.
Reviewed on Apr 10, 2026
Days Inn by Wyndham Florence/I-95 North
2111 West Lucas St/I-95 Florence SC
Fully refundableReserve now, pay when you stay
$54 nightly
The price is $60 total per night from Apr 29 to Apr 30
$60 total
Apr 29 - Apr 30
Total with taxes and fees
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this motel. Guests will appreciate free perks like on-the-go breakfast and ...
6.6/10 (1,007 reviews)
It was nice
Reviewed on Apr 24, 2026
Days Inn by Wyndham Dillon
823 Radford Blvd Dillon SC
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $64 total per night from May 11 to May 12
$64 total
May 11 - May 12
Total with taxes and fees
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like on-the-go breakfast and ...
5.4/10 (883 reviews)
OK
Reviewed on Apr 26, 2026
Clarion Inn & Suites Florence - Darlington
1819 West Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$47 nightly
The price is $52 total per night from May 13 to May 14
$52 total
May 13 - May 14
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Enjoy the seasonal outdoor pool and free perks like on-the-go breakfast and free self parking. A business ...
4.4/10 (322 reviews)
The floor was dirty. The fridge was nasty and smelly. The bedsheets had paint and big yellow stains all over it! Very disgusting place!
Reviewed on Apr 27, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Florence Luxury Hotels
Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Florence luxury hotels are the plush oasis you’ve been looking for.
Choose from the best luxury hotels in Florence to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.
We want you to enjoy your next vacation in style and the top luxury resorts in Florence will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Florence, and plan your next opulent escape.
Florence hotels essential information
Accommodation | 398 hotels |
|---|---|
Lowest Price | $52 |
Highest Price | $202 |
Popular hotels | The Mantissa Hotel, Days Inn by Wyndham Dillon, Hotel Florence, Tapestry Collection by Hilton, Days Inn by Wyndham Florence/I-95 North, Clarion Inn & Suites Florence - Darlington, Red Roof Inn Florence - Civic Center, Days Inn by Wyndham Florence Near Civic Center, Quality Inn Dillon |
Popular Luxury Stays in Florence
Recent Florence Hotel Reviews By Fellow Wanderers
Quality Inn & Suites Florence Civic Center
5 out of 5
Posted 9 hours ago
Travelocity Verified Review
"Clean room"
A verified traveler stayed at Quality Inn & Suites Florence Civic Center
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- Flights from Florence Regional
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