Cheap Flights to Florence from $172
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How Much Does it Cost To Fly To Florence?
The cheapest prices found with in the last 7 days for return flights were $299 and $172 for one-way flights to Florence for the period specified. Prices and availability are subject to change. Additional terms apply
ORD
O'Hare Intl.
FLO
Florence Regional
$347 Roundtrip, found 1 day ago
$347
Roundtrip
found 1 day ago
Florence Flight Information
Traveling to | Florence |
|---|---|
Lowest Price | $299 |
Number of Airlines Serving | |
Airlines Serving | American Airlines |
Number of Daily Flights | |
Airlines with Direct Flights |
Find The Perfect Hotel For After Your Flight
Amazing Florence Accommodation Deals
Red Roof Inn Florence - Civic Center
2690 David H McLeod Boulevard Florence SC
$56 nightly
The price is $63 total per night from Jun 1 to Jun 2
$63 total
Jun 1 - Jun 2
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.8/10 (1,000 reviews)
Smelled like smoke, junky
Reviewed on May 11, 2026
Budget Inn Timmonsville
2200 Cale Yarborough Highway Timmonsville SC
$61 nightly
The price is $68 total per night from May 17 to May 18
$68 total
May 17 - May 18
Total with taxes and fees
Stay at this motel in Timmonsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Florence Motor Speedway is located nearby.
7/10 Good! (341 reviews)
Wish at least coffee was offered in am. Parking right in front of room. Very clean overall. Bathroom sink needs worked, backs up of water. Room 109. Veey close to I-95 North, quick exit.
Reviewed on Apr 23, 2026
Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr Florence SC
$66 nightly
The price is $74 total per night from May 31 to Jun 1
$74 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,007 reviews)
Provide scramble eggs and bacon
Reviewed on May 16, 2026
Save an average of 15% on thousands of hotels when you're signed in
Spark by Hilton Florence North I-95, SC
1739 Mandeville Rd Florence SC
$93 nightly
The price is $104 total per night from May 25 to May 26
$104 total
May 25 - May 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (113 reviews)
Bed was comfortable and place quiet for our one night stay. The quality of breakfast not so great. Coffee could have been better
Reviewed on May 16, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Luxury Hotels in Florence
The Mantissa Hotel
130 East Carolina Ave Hartsville SC
$180 nightly
The price is $202 total per night from May 24 to May 25
$202 total
May 24 - May 25
Total with taxes and fees
Stay at this hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (288 reviews)
Adorable hotel. Great location in Hartsville
Reviewed on May 8, 2026
Days Inn by Wyndham Dillon
823 Radford Blvd Dillon SC
$55 nightly
The price is $62 total per night from Jun 16 to Jun 17
$62 total
Jun 16 - Jun 17
Total with taxes and fees
Stay at this hotel in Dillon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
5.4/10 (887 reviews)
All good.
Reviewed on May 16, 2026
Hotel Florence, Tapestry Collection by Hilton
126 W Evans St Florence SC
$130 nightly
The price is $146 total per night from May 24 to May 25
$146 total
May 24 - May 25
Total with taxes and fees
Book a stay at this spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (635 reviews)
We loved the Hotel Florence! It was our 1st visit to Florence..everyone we met were very nice. Loved the Cru Wine & Tap located in Hotel. Also ate at Victor's in the hotel it was delicious. Walkable to other shops, restaurants & bars.
Reviewed on May 7, 2026
Save an average of 15% on thousands of hotels when you're signed in
Days Inn by Wyndham Florence/I-95 North
2111 West Lucas St/I-95 Florence SC
$58 nightly
The price is $65 total per night from Jun 1 to Jun 2
$65 total
Jun 1 - Jun 2
Total with taxes and fees
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.6/10 (1,000 reviews)
Place was a dump.... It came up with great reviews and not sure HOW !?!? DO NOT BOOK THIS DUMP !! 😞
Reviewed on May 5, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Florence
Home2 Suites by Hilton Florence, SC
900 Woody Jones Blvd Florence SC
$119 nightly
The price is $133 total per night from May 31 to Jun 1
$133 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,007 reviews)
Large clean room with full size fridge. Only issue was not enough clean plates and silverware for breakfast buffet.
Reviewed on May 7, 2026
Spark by Hilton Florence North I-95, SC
1739 Mandeville Rd Florence SC
$93 nightly
The price is $104 total per night from May 25 to May 26
$104 total
May 25 - May 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (113 reviews)
Bed was comfortable and place quiet for our one night stay. The quality of breakfast not so great. Coffee could have been better
Reviewed on May 16, 2026
Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr Florence SC
$66 nightly
The price is $74 total per night from May 31 to Jun 1
$74 total
May 31 - Jun 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,007 reviews)
Provide scramble eggs and bacon
Reviewed on May 16, 2026
Save an average of 15% on thousands of hotels when you're signed in
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
3440 W Radio Dr Florence SC
$118 nightly
The price is $132 total per night from May 24 to May 25
$132 total
May 24 - May 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,002 reviews)
Room was very clean and comfortable. Were able to get a room 2 hours before arrival. Decent price for a 2 bed room.
Reviewed on May 16, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Best Florence Flight and Hotel Packages
Florence flight + hotel packages - economy flights
Price found within the past 48 hours. Click for updated prices.
Don't see what you're looking for?
See all available trips from San Francisco to Florence
View all tripsNeed a Car For After Your Flight?
Midsize SUV
Florence, South Carolina, USA
$65
$173 total
found 1 day ago
Compact SUV
Florence, South Carolina, USA
$65
$173 total
found 1 day ago
Standard SUV
Florence, South Carolina, USA
$69
$183 total
found 1 day ago
Fullsize
Florence, South Carolina, USA
$74
$194 total
found 1 day ago
Plane Tickets To Florence
Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Florence. Browse through our inventory to explore a wide range of cheap flights to Florence to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Florence as you anxiously await to exit the plane and explore what Florence has to offer. Considering all the amazing local food and culture in Florence, we won't hold this against you.
When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Florence to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Florence without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Florence with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Florence today!
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- American Airlines Asheville (AVL) to Florence (FLO) flights
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