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Top Otay Mesa 4 Star hotels

Hotel del Coronado, Curio Collection by Hilton

Hotel del Coronado, Curio Collection by Hilton

4 out of 5
1500 Orange Ave Coronado CA
Fully refundableReserve now, pay when you stay
$551 nightly
The price is $611 total per night from Feb 28 to Mar 1
$611 total
Feb 28 - Mar 1
Total with taxes and fees
A private beach, 6 restaurants, and an outdoor pool are all featured at this Victorian resort. Relax with sun loungers and beach umbrellas, and cool off with ...
8.6/10 Excellent! (1,009 reviews)
Staff is very friendly and helpful. It’s a gorgeous hotel.

Reviewed on Feb 21, 2026

Opens in a new windowHotel del Coronado, Curio Collection by Hilton
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
$254 nightly
The price is $294 total per night from Feb 23 to Feb 24
$294 total
Feb 23 - Feb 24
Total with taxes and fees
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free ...
9/10 Wonderful! (3,340 reviews)
Excellent service

Reviewed on Feb 21, 2026

Opens in a new windowHard Rock Hotel San Diego
DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

4 out of 5
7450 Hazard Center Dr San Diego CA
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $166 total per night from Mar 1 to Mar 2
$166 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 20 conference rooms, free WiFi in public areas, ...
8.4/10 Very Good! (1,540 reviews)
Staff was great, very friendly! Loved the location and the room.

Reviewed on Feb 17, 2026

Opens in a new windowDoubleTree by Hilton Hotel San Diego - Mission Valley
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

4 out of 5
1646 Front St San Diego CA
Fully refundableReserve now, pay when you stay
$184 nightly
The price is $213 total per night from Mar 12 to Mar 13
$213 total
Mar 12 - Mar 13
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free internet ...
9/10 Wonderful! (385 reviews)
Really nice place I will totally recommend it !!

Reviewed on Feb 21, 2026

Opens in a new windowCourtyard by Marriott San Diego Downtown Little Italy
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S San Diego CA
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $141 total per night from Mar 1 to Mar 2
$141 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
8/10 Very Good! (2,331 reviews)
Room spotless and staff was friendly.

Reviewed on Feb 19, 2026

Opens in a new windowHilton San Diego Mission Valley
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$180 nightly
The price is $207 total per night from Mar 18 to Mar 19
$207 total
Mar 18 - Mar 19
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9.2/10 Wonderful! (2,958 reviews)
Great Place To Stay

Reviewed on Feb 22, 2026

Opens in a new windowLegacy Resort Hotel & Spa
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
Fully refundableReserve now, pay when you stay
$184 nightly
The price is $213 total per night from Mar 1 to Mar 2
$213 total
Mar 1 - Mar 2
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
8.4/10 Very Good! (6,052 reviews)
Great location but hotel most certainly needs updating. Beds were good

Reviewed on Feb 21, 2026

Opens in a new windowWyndham San Diego Bayside
Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown

4 out of 5
601 Pacific Hwy San Diego CA
Fully refundableReserve now, pay when you stay
$203 nightly
The price is $235 total per night from Mar 1 to Mar 2
$235 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, express check-in, and valet ...
9/10 Wonderful! (1,645 reviews)
Husband and I decided to visit San Diego last minute and after researching the downtown area decided the location of ES fit us perfectly. Short walk from the 992 bus stop to and from the airport. We booked through Expedia and selected a King Corner Suite. We had a wonderful view of the Harbor and ...

Reviewed on Feb 21, 2026

Opens in a new windowEmbassy Suites by Hilton San Diego Bay Downtown
Lafayette Hotel & Club

Lafayette Hotel & Club

4 out of 5
2223 El Cajon Blvd San Diego CA
Fully refundableReserve now, pay when you stay
$229 nightly
The price is $263 total per night from Feb 23 to Feb 24
$263 total
Feb 23 - Feb 24
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...
9.4/10 Exceptional! (1,486 reviews)
A totally unique and wonderful experience!

Reviewed on Feb 22, 2026

Opens in a new windowLafayette Hotel & Club
Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

4 out of 5
1433 Camino Del Rio S San Diego CA
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $155 total per night from Feb 26 to Feb 27
$155 total
Feb 26 - Feb 27
Total with taxes and fees
This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
8.6/10 Excellent! (1,731 reviews)
Staff was very curteous. Room could have been cleaner ie bugs in light in bathroom, thick dust on ledges of bed headboard. stains on dust ruffles. Empty body wash in shower. Would have expected better from Sheraton.

Reviewed on Feb 22, 2026

Opens in a new windowSheraton Mission Valley San Diego Hotel
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