Explore top 2025 4 Star Hotels in Otay Mesa

Name: Sheraton Mission Valley San Diego Hotel
Price range: $136 total
Rating: 8.4

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Top Otay Mesa 4 Star hotels

Hotel del Coronado, Curio Collection by Hilton

1500 Orange Ave Coronado CA

Fully refundableReserve now, pay when you stay

$389 nightly

$432 total

Nov 23 - Nov 24

Total with taxes and fees

A private beach, 6 restaurants, and an outdoor pool are all featured at this Victorian resort. Relax with sun loungers and beach umbrellas, and cool off with ...

8.4/10 Very Good! (1,007 reviews)

Room was nice, walkability was great. On site amenities made the stay easy traveling with a toddler.

Reviewed on Nov 18, 2025

Hard Rock Hotel San Diego

207 5th Ave San Diego CA

Fully refundableReserve now, pay when you stay

$307 nightly

$355 total

Nov 27 - Nov 28

Total with taxes and fees

A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free ...

8.8/10 Excellent! (3,081 reviews)

Staff was great Our suite was extremely nice the sound system was great. Gaslamp area was great lots of great food.

Reviewed on Nov 17, 2025

DoubleTree by Hilton Hotel San Diego - Mission Valley

7450 Hazard Center Dr San Diego CA

Fully refundableReserve now, pay when you stay

$110 nightly

$126 total

Nov 30 - Dec 1

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 20 conference rooms, free WiFi in public areas, ...

8.2/10 Very Good! (1,348 reviews)

Nice cookies! Good clean rooms.

Reviewed on Nov 20, 2025

Courtyard by Marriott San Diego Downtown Little Italy

1646 Front St San Diego CA

Fully refundable

$105 nightly

$122 total

Nov 27 - Nov 28

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free internet ...

8.2/10 Very Good! (1,233 reviews)

Nice clean room with nice balcony. Nice neighborhood. Friendly staff.

Reviewed on Nov 18, 2025

Hilton San Diego Mission Valley

901 Camino Del Rio S San Diego CA

Fully refundableReserve now, pay when you stay

$114 nightly

$131 total

Nov 30 - Dec 1

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...

8/10 Very Good! (2,181 reviews)

Staff was very friendly and helpful.

Reviewed on Nov 16, 2025

Legacy Resort Hotel & Spa

875 Hotel Circle South San Diego CA

Fully refundableReserve now, pay when you stay

$125 nightly

$144 total

Nov 24 - Nov 25

Total with taxes and fees

A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

9/10 Wonderful! (2,946 reviews)

Everything was perfect except the view from out balcony it was just a bit hill of dirt and trees

Reviewed on Nov 18, 2025

Wyndham San Diego Bayside

1355 N Harbor Drive San Diego CA

Fully refundableReserve now, pay when you stay

$160 nightly

$186 total

Nov 23 - Nov 24

Total with taxes and fees

This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

8.4/10 Very Good! (6,041 reviews)

Staff, cleanliness, and room outstanding

Reviewed on Nov 21, 2025

Embassy Suites by Hilton San Diego Bay Downtown

601 Pacific Hwy San Diego CA

Fully refundableReserve now, pay when you stay

$198 nightly

$230 total

Nov 30 - Dec 1

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, express check-in, and valet ...

9/10 Wonderful! (1,529 reviews)

The Embassy Suites San Diego Bay was in a great location. The staff were very accommodating and the room was clean! We stayed the night before a cruise. It was close to the port. It was quite walkable, but we elected to take a cab due to the size of our suitcases. Lots of choices for dinner. We would ...

Reviewed on Nov 20, 2025

Lafayette Hotel & Club

2223 El Cajon Blvd San Diego CA

Fully refundableReserve now, pay when you stay

$226 nightly

$259 total

Nov 24 - Nov 25

Total with taxes and fees

This smoke-free hotel features 2 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...

9.2/10 Wonderful! (1,267 reviews)

The hotel is beautiful art deco and was already wonderfully decorated for Xmas. The staff is very helpful and friendly. The food is delicious and LuLu's club is a fantastic venue. This is a must stay in San Diego and great for a staycation like we did.

Reviewed on Nov 15, 2025

Sheraton Mission Valley San Diego Hotel

1433 Camino Del Rio S San Diego CA

Fully refundableReserve now, pay when you stay

$118 nightly

$136 total

Nov 25 - Nov 26

Total with taxes and fees

This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

8.4/10 Very Good! (1,619 reviews)

The room was a great size and super clean, the staff is super nice

Reviewed on Nov 19, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.