Book Hotels in Effingham, SC

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Top Effingham hotels

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Fully refundable
$85 nightly
The price is $95 total per night from Jun 14 to Jun 15
$95 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the free ...
"The gentleman at the check in was highly efficient. The room was clean and bed was comfortable. The room AC worked great. The breakfast area was spotless and the coffee was good. The lady attending was on point."

Reviewed on Jun 8, 2026

Opens in a new windowPark Inn by Radisson Florence, SC
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
Fully refundable
$113 nightly
The price is $126 total per night from Jul 5 to Jul 6
$126 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
"Breakfast on Monday to Friday is at 6:30 by then a working person would be late for work any ways on Sunday who wants to eat eggs and fried hot dogs. That was only time I had breakfast. Cleaning personal were beyond hope 10 day stay cleaned my room 1 time. Had to beg them to clean it for 3 day before ..."

Reviewed on Jun 8, 2026

Opens in a new windowComfort Inn & Suites Florence Center Area
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $128 total per night from Jul 6 to Jul 7
$128 total
Jul 6 - Jul 7
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"enjoyed the stay"

Reviewed on Jun 8, 2026

Opens in a new windowHyatt Place Florence Downtown
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $99 total per night from Jun 9 to Jun 10
$99 total
Jun 9 - Jun 10
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Clean room, staff was so kind and helpful."

Reviewed on Jun 7, 2026

Opens in a new windowQuality Inn & Suites Florence Civic Center
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Jun 14 to Jun 15
$79 total
Jun 14 - Jun 15
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Room was clean. Was unable to stay for breakfast. Ample parking options made it easy to park and truck and trailer. I’d suggest 2nd floor rooms vs ground floor."

Reviewed on Jun 8, 2026

Opens in a new windowHoward Johnson by Wyndham Florence
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

2.5 out of 5
2101 Florence Harllee Blvd Florence SC
Fully refundable
$127 nightly
The price is $142 total per night from Jun 14 to Jun 15
$142 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"The evening staff young man didn't know anything. He needs more training!"

Reviewed on Jun 5, 2026

Opens in a new windowHoliday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd Florence SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $95 total per night from Jun 21 to Jun 22
$95 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"We stayed this weekend and it was a great experience. The pool situation was a lot confusing with the times but overall good experience… I would stay again.. Also our housekeeper can’t remember her name Jennifer or Jessica was very helpful.. she went out her way to get us some towels❤️"

Reviewed on Jun 7, 2026

Opens in a new windowSpark by Hilton Florence North I-95, SC
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

3 out of 5
2123 W Lucas St Florence SC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $94 total per night from Jun 9 to Jun 10
$94 total
Jun 9 - Jun 10
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Very clean, everyone was very courteous area seemed very safe would book again"

Reviewed on Jun 6, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Florence
Super 8 by Wyndham Florence

Super 8 by Wyndham Florence

2 out of 5
1832 1/2 Lucas Street, I95 Exit 164 Florence SC
Fully refundable
$54 nightly
The price is $60 total per night from Jun 10 to Jun 11
$60 total
Jun 10 - Jun 11
Total with taxes and fees
A seasonal outdoor pool is featured at this motel, along with free self parking. Guests will appreciate free perks like on-the-go breakfast and WiFi in public ...
"The room was very clean, staff was very pleasant, parking was very convenient, and the air conditioning worked very well. The only thing that was troubling is that you had to ask for a coffee machine for the room, along with the coffee, sugar, and creamers. I remember, in the past, there was always ..."

Reviewed on Jun 6, 2026

Opens in a new windowSuper 8 by Wyndham Florence
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Effingham?
Family getaways are where treasured memories are made, but it's no secret that traveling with little ones can be tricky. These kid-friendly Effingham hotels come with perks designed to keep visitors of all ages relaxed and happy: Put your bags down at Cheerful home with plenty of privacy and entertainment room.. It comes with a fireplace, free WiFi and a knack for making families feel welcome. Otherwise, spend your Effingham break at Walking distance from one of South Carolinas top Medical centers.. Take advantage of free WiFi, clothes washing facilities and more here.
Where can I find cheap hotels in Effingham?
At Travelocity you'll find really nice hotels in Effingham at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Effingham rather than in Effingham. We may find you even better rates, too.
How do I find the best Effingham hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Effingham then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Effingham?
The cheapest hotel in Effingham is $60. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Effingham?
There are 158 hotels in Effingham on Travelocity.
What are the best hotels in Effingham?
Effingham has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Effingham for you!
When is the best time to visit Effingham?
If you want the joy of a fun-filled trip in peak season, visit Effingham during March, April and July. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, September and October.
When is the cheapest time to stay in Effingham?
Based on historic data is usually the cheapest month to visit Effingham. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Effingham?
There are multiple hotels in Effingham that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Effingham. We have plenty of kid-friendly hotels in Effingham to choose from on Travelocity!
Why book a hotel in Effingham through Travelocity?
Because we have the top hotels in Effingham! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Effingham on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Effingham hotel reviews by fellow wanderers

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

4 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Breakfast on Monday to Friday is at 6:30 by then a working person would be late for work any ways on Sunday who wants to eat eggs and fried hot dogs. That was only time I had breakfast. Cleaning personal were beyond hope 10 day stay cleaned my room 1 time. Had to beg them to clean it for 3 day before they did something."
A verified traveler stayed at Comfort Inn & Suites Florence Center Area
Comfort Inn & Suites Florence Center Area

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