Explore top 2026 4 Star Hotels in Otay Mesa

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Top Otay Mesa 4 Star hotels

Hotel del Coronado, Curio Collection by Hilton

Hotel del Coronado, Curio Collection by Hilton

4 out of 5
1500 Orange Ave Coronado CA
$426 nightly
The price is $473 total per night from Jan 25 to Jan 26
$473 total
Jan 25 - Jan 26
Total with taxes and fees
A private beach, 6 restaurants, and an outdoor pool are all featured at this Victorian resort. Relax with sun loungers and beach umbrellas, and cool off with ...
8.4/10 Very Good! (1,004 reviews)
The room was spacious and the view was amazing. Lovely hotel with lots of history! I definitely recommend it!

Reviewed on Jan 20, 2026

Opens in a new windowHotel del Coronado, Curio Collection by Hilton
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
$237 nightly
The price is $274 total per night from Jan 23 to Jan 24
$274 total
Jan 23 - Jan 24
Total with taxes and fees
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free ...
8.8/10 Excellent! (3,232 reviews)
The room was a great deal!! It was really spacious. We loved that the toilet and the shower was on two seperate sides of the bathroom.. however the bed was like sleeping on a floor, the sliding doors took extreme manpower to open so paying extra for a balcony wasnt worth it and the toilet made the ...

Reviewed on Jan 17, 2026

Opens in a new windowHard Rock Hotel San Diego
DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

4 out of 5
7450 Hazard Center Dr San Diego CA
$134 nightly
The price is $154 total per night from Jan 25 to Jan 26
$154 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 20 conference rooms, free WiFi in public areas, ...
8.2/10 Very Good! (1,483 reviews)
Great

Reviewed on Jan 17, 2026

Opens in a new windowDoubleTree by Hilton Hotel San Diego - Mission Valley
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

4 out of 5
1646 Front St San Diego CA
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $187 total per night from Feb 22 to Feb 23
$187 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free internet ...
8.8/10 Excellent! (257 reviews)
Hotel was good . We stayed for one night . I had paid for breakfast included. However hotel front desk cant see that . Until I insisted they could Not see it. It happened with multiple folks so something to watchout . Overall pretty decent place to stay for one night.

Reviewed on Jan 17, 2026

Opens in a new windowCourtyard by Marriott San Diego Downtown Little Italy
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S San Diego CA
$128 nightly
The price is $147 total per night from Jan 25 to Jan 26
$147 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
8/10 Very Good! (2,288 reviews)
Clean

Reviewed on Jan 20, 2026

Opens in a new windowHilton San Diego Mission Valley
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$172 nightly
The price is $198 total per night from Jan 27 to Jan 28
$198 total
Jan 27 - Jan 28
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9/10 Wonderful! (2,932 reviews)
Yes

Reviewed on Jan 16, 2026

Opens in a new windowLegacy Resort Hotel & Spa
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
Fully refundableReserve now, pay when you stay
$182 nightly
The price is $211 total per night from Jan 25 to Jan 26
$211 total
Jan 25 - Jan 26
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
8.4/10 Very Good! (5,994 reviews)
Hotel is pretty old exterior but staff was friendly and welcoming, Claim Jumper and Ruth Chris restaurants are on the property w

Reviewed on Jan 22, 2026

Opens in a new windowWyndham San Diego Bayside
Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown

4 out of 5
601 Pacific Hwy San Diego CA
$232 nightly
The price is $269 total per night from Feb 1 to Feb 2
$269 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, express check-in, and valet ...
9/10 Wonderful! (1,582 reviews)
Spacious rooms, clean. Liked the breakfast and snakc option in evening

Reviewed on Jan 19, 2026

Opens in a new windowEmbassy Suites by Hilton San Diego Bay Downtown
Lafayette Hotel & Club

Lafayette Hotel & Club

4 out of 5
2223 El Cajon Blvd San Diego CA
Fully refundableReserve now, pay when you stay
$229 nightly
The price is $263 total per night from Jan 26 to Jan 27
$263 total
Jan 26 - Jan 27
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...
9.2/10 Wonderful! (1,420 reviews)
my best friend and i stay here annually for her birthday and it's ALWAYS the best time! we love EVERYTHING from the vibes to the food and delicious poolside drinks + hanging at the lobby bar. also - COMFIEST BEDS AND BEDDING EVER

Reviewed on Jan 15, 2026

Opens in a new windowLafayette Hotel & Club
Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

4 out of 5
1433 Camino Del Rio S San Diego CA
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $155 total per night from Jan 29 to Jan 30
$155 total
Jan 29 - Jan 30
Total with taxes and fees
This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
8.4/10 Very Good! (1,718 reviews)
Dinner was good bar tender was awesome drinks were good. Quick stay but felt welcome and comfortable

Reviewed on Jan 8, 2026

Opens in a new windowSheraton Mission Valley San Diego Hotel
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Recent Otay Mesa hotel reviews by fellow wanderers

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Yes"
A verified traveler stayed at Manchester Grand Hyatt San Diego
Manchester Grand Hyatt San Diego

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