Explore top 2026 4 Star Hotels in Otay Mesa

Name: Marriott Marquis San Diego Marina
Price range: $440 total
Rating: 9.2

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Top Otay Mesa 4 Star hotels

Manchester Grand Hyatt San Diego

1 Market Pl San Diego CA

Fully refundableReserve now, pay when you stay

$306 nightly

$355 total

Jul 1 - Jul 2

Total with taxes and fees

This hotel features 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

9/10 Wonderful! (2,804 reviews)

"Fantastic place, staff was excellent and location next to sea port village was amazing"

Reviewed on Jun 9, 2026

San Diego Mission Bay Resort

1775 E Mission Bay Dr San Diego CA

Fully refundableReserve now, pay when you stay

$315 nightly

$362 total

Jun 14 - Jun 15

Total with taxes and fees

A full-service spa, 2 restaurants, and 5 outdoor tennis courts are all featured at this Mediterranean resort. There's fun for all ages with a children's pool ...

8.6/10 Excellent! (1,478 reviews)

"Do not stay here! The pictures are deceiving. The rooms smelled like mold and wet dog. Our family checked out within hours of checking in. The worst part is the Director “Grant” kept dodging communication from Expedia for a refund after I was guaranteed one at the front desk when leaving. I still ..."

Reviewed on Jun 11, 2026

Hard Rock Hotel San Diego

207 5th Ave San Diego CA

$193 nightly

$224 total

Jun 14 - Jun 15

Total with taxes and fees

A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free ...

9/10 Wonderful! (3,822 reviews)

"Great hotel and location is perfect for Radys Shell, Gaslamp or Petco Park"

Reviewed on Jun 10, 2026

Loews Coronado Bay Resort

4000 Coronado Bay Rd Coronado CA

Fully refundableReserve now, pay when you stay

$307 nightly

$341 total

Jul 1 - Jul 2

Total with taxes and fees

A full-service spa, a marina, and 3 outdoor pools are all featured at this hotel. Take the free beach shuttle and relax with sun loungers and beach umbrellas. ...

9/10 Wonderful! (1,108 reviews)

"Loved it!"

Reviewed on Jun 10, 2026

Wyndham San Diego Bayside

1355 N Harbor Drive San Diego CA

$182 nightly

$211 total

Jun 14 - Jun 15

Total with taxes and fees

This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center and free WiFi in public ...

Hotel del Coronado, Curio Collection by Hilton

1500 Orange Ave Coronado CA

Fully refundableReserve now, pay when you stay

$602 nightly

$668 total

Jun 30 - Jul 1

Total with taxes and fees

A private beach, 6 restaurants, and an outdoor pool are all featured at this Victorian resort. Relax with sun loungers and beach umbrellas, and cool off with ...

8.6/10 Excellent! (1,021 reviews)

"Unfortunately, we were roomed with the loading dock as our view. The dock activity was constant and noisy disrupting our entire stay. The ocean activity was non-existent as the water was unsafe for entry. The jacuzzi/hot tub was so busy and not hot. Too many strikes for me to recommend or ..."

Reviewed on Jun 11, 2026

Omni San Diego Hotel at the Ballpark

675 L St San Diego CA

Fully refundableReserve now, pay when you stay

$222 nightly

$258 total

Jun 15 - Jun 16

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

9.2/10 Wonderful! (2,235 reviews)

"Super easy check in. We got to the hotel super early hoping to store our luggage for a 1:10 padres game. We were given a key to use the pool and lounge area on the 6th floor and before we could get settled we were notified a room was ready for us! A bellman grabbed our luggage and headed to our room. ..."

Reviewed on Jun 9, 2026

Sheraton San Diego Resort

1380 Harbor Island Dr San Diego CA

Fully refundableReserve now, pay when you stay

$203 nightly

$234 total

Jul 1 - Jul 2

Total with taxes and fees

A marina, 5 restaurants, and 3 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi ...

8.4/10 Very Good! (3,534 reviews)

"Great place! Beautiful location, awesome food, amenities, staff, view, etc. Will definitely stay again."

Reviewed on Jun 11, 2026

San Diego Marriott Gaslamp Quarter

660 K St San Diego CA

$189 nightly

$219 total

Jun 14 - Jun 15

Total with taxes and fees

A nightclub, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, express ...

8.8/10 Excellent! (1,675 reviews)

"The room was clean and we had a great view."

Reviewed on Jun 11, 2026

Marriott Marquis San Diego Marina

333 W Harbor Dr San Diego CA

$380 nightly

$440 total

Jul 5 - Jul 6

Total with taxes and fees

A marina, 5 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Bring the family and enjoy the children's pool and kid-friendly dining. ...

9.2/10 Wonderful! (2,186 reviews)

"I didn't like the front desk tried to cheat me out of the deluxe room I"

Reviewed on Jun 10, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.