Explore top 2025 5 Star Hotels in South San Diego

Name: The Bower Coronado
Price range: $302 total
Rating: 9.2

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Top South San Diego 5 Star hotels

Pendry San Diego

550 J Street, San Diego, CA

Fully refundableReserve now, pay when you stay

$300 nightly

$348 total

Oct 30 - Oct 31

Total with taxes and fees

A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...

9.2/10 Wonderful! (1,013 reviews)

"Great! Would stay again"

Reviewed on Sep 22, 2025

The US Grant, a Luxury Collection Hotel, San Diego

326 Broadway, San Diego, CA

Fully refundableReserve now, pay when you stay

$278 nightly

$322 total

Oct 19 - Oct 20

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, express check-out, and ...

9/10 Wonderful! (1,000 reviews)

"I can’t say enough wonderful things about our stay at The U.S. Grant! We arrived a bit later than planned for our Thursday night celebration, and yet Manager Kim and the entire team went above and beyond to make it truly special for my wife and me. The food was absolutely delicious, and the service ..."

Reviewed on Sep 22, 2025

The Bower Coronado

1417 Orange Ave, Coronado, CA

Fully refundableReserve now, pay when you stay

$279 nightly

$302 total

Oct 5 - Oct 6

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...

9.2/10 Wonderful! (109 reviews)

"Modern and great location. No pool at the property."

Reviewed on Sep 26, 2025

Beach Village at The Del, LXR Hotels & Resorts

1500 Orange Avenue, Coronado, CA

Fully refundableReserve now, pay when you stay

$783 nightly

$863 total

Oct 27 - Oct 28

Total with taxes and fees

A private beach, 7 restaurants, and 3 outdoor pools are all featured at this smoke-free resort. Enjoy beachfront dining and relax with beach cabanas and sun ...

9/10 Wonderful! (115 reviews)

"X"

Reviewed on Sep 24, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

South San Diego Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in South San Diego to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. South San Diego 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in South San Diego before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.