Book Hotels in South San Diego, CA

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight
Dec 14 - Dec 15
Tomorrow
Dec 15 - Dec 16
Next weekend
Dec 19 - Dec 21
In two weeks
Dec 26 - Dec 28

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top South San Diego hotels

Lafayette Hotel & Club

Lafayette Hotel & Club

4 out of 5
2223 El Cajon Blvd San Diego CA
Fully refundableReserve now, pay when you stay
$229 nightly
The price is $263 total per night from Dec 29 to Dec 30
$263 total
Dec 29 - Dec 30
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...
The hotel is big on charm and decor. It was in 1937 and the guest rooms haven’t been enlarged or highly modernized. What they did get is a big dash of kitsch. Clashing wall paper, canopied beds, retro appliances, and a huge room bar (you pay per drink). We took a second floor poolside room with a ...

Reviewed on Dec 11, 2025

Opens in a new windowLafayette Hotel & Club
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

3.5 out of 5
800 Bay Marina Dr National City CA
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $118 total per night from Dec 21 to Dec 22
$118 total
Dec 21 - Dec 22
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Bring the family and enjoy the mini golf, children's pool, and kid-friendly ...
En general el hotel está bien, es limpio, tiene excelente ubicación y el personal brinda excelente atención, solo falta un poco de mantenimiento ya que especialmente el baño estaba un poco deteriorado

Reviewed on Dec 12, 2025

Opens in a new windowBest Western Plus Marina Gateway Hotel
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $175 total per night from Dec 15 to Dec 16
$175 total
Dec 15 - Dec 16
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
Very well and clean

Reviewed on Dec 12, 2025

Opens in a new windowLegacy Resort Hotel & Spa
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $160 total per night from Dec 18 to Dec 19
$160 total
Dec 18 - Dec 19
Total with taxes and fees
A marina, a gym, and a restaurant are all featured at this traditional hotel. Traveling on business? Take advantage of the free WiFi in public areas and free ...
The lady working the front desk was really nice. Excellent customer service. The room was amazing, spectacular view!

Reviewed on Dec 9, 2025

Opens in a new windowBay Club Hotel & Marina
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $120 total per night from Dec 28 to Dec 29
$120 total
Dec 28 - Dec 29
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Quite area. Close to Little Italy.

Reviewed on Dec 11, 2025

Opens in a new windowThe DEXTRO Little Italy, BW Premier Collection
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
$210 nightly
The price is $243 total per night from Jan 1 to Jan 2
$243 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free ...
Location is amazing. Nice room. Highly recommend to stay this hotel

Reviewed on Dec 10, 2025

Opens in a new windowHard Rock Hotel San Diego
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

4 out of 5
1646 Front St San Diego CA
Fully refundable
$110 nightly
The price is $128 total per night from Dec 22 to Dec 23
$128 total
Dec 22 - Dec 23
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free internet ...
The staff was amazing , the property recently remodeled very modern and luxurious Room spacious and comfortable Walking distance to Little Italy and the Pier Will definitely stay there again

Reviewed on Dec 11, 2025

Opens in a new windowCourtyard by Marriott San Diego Downtown Little Italy
San Diego Marriott La Jolla

San Diego Marriott La Jolla

4 out of 5
4240 La Jolla Village Dr La Jolla CA
Fully refundableReserve now, pay when you stay
$163 nightly
The price is $187 total per night from Jan 9 to Jan 10
$187 total
Jan 9 - Jan 10, 2026
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Great convenient spot away from all the traffic madness of the village. Thomas at the front desk was outstanding. $40 parking and $40 breakfasts was ridiculous!

Reviewed on Dec 8, 2025

Opens in a new windowSan Diego Marriott La Jolla
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $144 total per night from Jan 4 to Jan 5
$144 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
A marina, 5 restaurants, and 3 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi ...
Shuttle was easy to find

Reviewed on Dec 10, 2025

Opens in a new windowSheraton San Diego Resort
Don't see what you're looking for?
See all available properties in South San Diego
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap South San Diego hotels

The Rambler

The Rambler

225 Bay Blvd Chula Vista CA
$91 nightly
The price is $106 total per night from Dec 15 to Dec 16
$106 total
Dec 15 - Dec 16
Total with taxes and fees
9/10 Wonderful! (1,997 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent South San Diego hotel reviews by fellow wanderers

Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

5 out of 5
Posted 20 hours ago
Travelocity Verified Review
"Comfy"
A verified traveler from North Hollywood stayed at Hampton Inn & Suites by Hilton San Diego SeaWorld
Hampton Inn & Suites by Hilton San Diego SeaWorld

Explore More Ways to Travel with Travelocity