Book Hotels in South San Diego, CA
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Top South San Diego hotels

Hampton Inn & Suites by Hilton San Diego SeaWorld
3888 Greenwood St San Diego CA
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $146 total per night from Mar 1 to Mar 2
$146 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features an outdoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the hot tub and free buffet breakfast ...
the room smell like pets and there's no parking available
Reviewed on Feb 17, 2026

Bay Club Hotel & Marina
2131 Shelter Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $160 total per night from Feb 24 to Feb 25
$160 total
Feb 24 - Feb 25
Total with taxes and fees
A marina, a gym, and a restaurant are all featured at this traditional hotel. Traveling on business? Take advantage of the free WiFi in public areas and free ...
Rooms are okay i think if they renovate it would be a lot better
Reviewed on Feb 17, 2026

Hard Rock Hotel San Diego
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
$254 nightly
The price is $294 total per night from Feb 22 to Feb 23
$294 total
Feb 22 - Feb 23
Total with taxes and fees
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free ...
Room was perfect
Reviewed on Feb 17, 2026

The DEXTRO Little Italy, BW Premier Collection
1617 1st Avenue San Diego CA
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $135 total per night from Feb 22 to Feb 23
$135 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
The first room they put us in was not what we had paid for which was supposed to be a king bed on top floor with city views. Instead they offered us a two double beds on the freeway side which was like sleeping on the freeway…almost. In the morning I tried to take a shower and only the hot and boiling ...
Reviewed on Feb 17, 2026

The Dana on Mission Bay
1710 W Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
$184 nightly
The price is $212 total per night from Feb 22 to Feb 23
$212 total
Feb 22 - Feb 23
Total with taxes and fees
A marina, 2 outdoor pools, and 2 hot tubs are all featured at this smoke-free hotel. If you want to take your pet along, this pet-friendly property offers everything ...
All Staff was very friendly. I was allowed to check in early no questions asked. I will definitely be going back.
Reviewed on Feb 17, 2026

Paradise Point Resort & Spa
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
$222 nightly
The price is $255 total per night from Mar 1 to Mar 2
$255 total
Mar 1 - Mar 2
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 2 restaurants. Family-friendly amenities include mini golf and kid-friendly dining, along with ...
The room and view was great, it was very easy to request towels etc. the staff were very friendly.
Reviewed on Feb 17, 2026

The Sofia Hotel
150 W Broadway San Diego CA
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $171 total per night from Mar 2 to Mar 3
$171 total
Mar 2 - Mar 3
Total with taxes and fees
A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
The room was so expensive when we got in it was so small the windows did not open they were sealed and blocked so there was no view. Worst things all there hidden fees they took $250 deposit on my credit card and charged every penny for different made up resort and taxes they were charging daily ...
Reviewed on Feb 17, 2026

Days Inn by Wyndham San Diego Hotel Circle
543 Hotel Circle S San Diego CA
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $92 total per night from Feb 22 to Feb 23
$92 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...
Room was clean, housekeeping staff very attentive. Gina at the front desk was awesome when we extended our stay.
Reviewed on Feb 17, 2026

Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
Fully refundableReserve now, pay when you stay
$182 nightly
The price is $211 total per night from Mar 1 to Mar 2
$211 total
Mar 1 - Mar 2
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
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See all available properties in South San Diego
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap South San Diego hotels

The Rambler
225 Bay Blvd Chula Vista CA
$107 nightly
The price is $124 total per night from Mar 1 to Mar 2
$124 total
Mar 1 - Mar 2
Total with taxes and fees
9.2/10 Wonderful! (2,050 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in South San Diego with star-rating
Check South San Diego Hotels by Star Rating

5 Star Hotels
5 properties
Recent South San Diego hotel reviews by fellow wanderers

The DEXTRO Little Italy, BW Premier Collection
5 out of 5
Posted 4 hours ago
Travelocity Verified Review
"Great location! "
A verified traveler stayed at The DEXTRO Little Italy, BW Premier Collection
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