Book Hotels in South San Diego, CA

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Top South San Diego hotels

Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $160 total per night from Sep 30 to Oct 1
$160 total
Sep 30 - Oct 1
Total with taxes and fees
A marina, a gym, and a restaurant are all featured at this traditional hotel. Traveling on business? Take advantage of the free WiFi in public areas and free ...
"Great calm place"

Reviewed on Sep 25, 2025

Opens in a new windowBay Club Hotel & Marina
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
Fully refundableReserve now, pay when you stay
$266 nightly
The price is $308 total per night from Oct 4 to Oct 5
$308 total
Oct 4 - Oct 5
Total with taxes and fees
This eco-certified hotel includes 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi ...
"The hotel is nice but more tailored for the convention fare & less of a resort ambiance. Service was efficient yet impersonal & why no concierge? They make a hotel experience."

Reviewed on Sep 22, 2025

Opens in a new windowManchester Grand Hyatt San Diego
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
$165 nightly
The price is $190 total per night from Oct 26 to Oct 27
$190 total
Oct 26 - Oct 27
Total with taxes and fees
A marina, 2 outdoor pools, and 2 hot tubs are all featured at this smoke-free hotel. If you want to take your pet along, this pet-friendly property offers everything ...
"good"

Reviewed on Sep 24, 2025

Opens in a new windowThe Dana on Mission Bay
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave, San Diego, CA
Fully refundableReserve now, pay when you stay
$295 nightly
The price is $342 total per night from Oct 20 to Oct 21
$342 total
Oct 20 - Oct 21
Total with taxes and fees
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free ...
"Perfect stay"

Reviewed on Sep 25, 2025

Opens in a new windowHard Rock Hotel San Diego
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue, San Diego, CA
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $138 total per night from Oct 5 to Oct 6
$138 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Clean room"

Reviewed on Sep 27, 2025

Opens in a new windowThe DEXTRO Little Italy, BW Premier Collection
Palihotel San Diego Gaslamp Quarter

Palihotel San Diego Gaslamp Quarter

4 out of 5
830 Sixth Avenue, San Diego, CA
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $139 total per night from Oct 23 to Oct 24
$139 total
Oct 23 - Oct 24
Total with taxes and fees
This hotel features a restaurant and 2 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and dry cleaning are also offered.
"Nice room!"

Reviewed on Sep 26, 2025

Opens in a new windowPalihotel San Diego Gaslamp Quarter
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive, San Diego, CA
Fully refundableReserve now, pay when you stay
$177 nightly
The price is $205 total per night from Oct 1 to Oct 2
$205 total
Oct 1 - Oct 2
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, express check-out, and ...
"Beautiful San Diego. Beautiful view from the balcony of Wyndham Bay Side. Everything easily accessible."

Reviewed on Sep 23, 2025

Opens in a new windowWyndham San Diego Bayside
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $116 total per night from Sep 30 to Oct 1
$116 total
Sep 30 - Oct 1
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
Nice hotel
"The hotel was very nice, if a little dated, with a really nice pool area! It felt safe and I slept well here! The air conditioner was quiet which is a bonus in any hotel!"

Reviewed on Sep 25, 2025

Opens in a new windowHandlery Hotel
Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld

3 out of 5
3737 Sports Arena Blvd, San Diego, CA
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $108 total per night from Oct 5 to Oct 6
$108 total
Oct 5 - Oct 6
Total with taxes and fees
An outdoor pool, self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Traveling on business? Take advantage of the ...
"close to sea world"

Reviewed on Sep 23, 2025

Opens in a new windowWyndham Garden San Diego Near SeaWorld
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap South San Diego hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent South San Diego hotel reviews by fellow wanderers

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