Book Hotels in South San Diego, CA

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Top South San Diego hotels

Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark

4 out of 5
675 L St San Diego CA
$308 nightly
The price is $357 total per night from Oct 5 to Oct 6
$357 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"Very limited pool bar hours even in August, but otherwise a really great stay!"

Reviewed on Oct 1, 2026

Opens in a new windowOmni San Diego Hotel at the Ballpark
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $119 total per night from Oct 5 to Oct 6
$119 total
Oct 5 - Oct 6
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
"All good except they need to stock the vending machines"

Reviewed on Oct 2, 2026

Opens in a new windowHandlery Hotel
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $97 total per night from Oct 4 to Oct 5
$97 total
Oct 4 - Oct 5
Total with taxes and fees
2 hot tubs, an outdoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi ...
"My room was clean, and the grounds were well maintained. The staff was friendly and helpful."

Reviewed on Oct 1, 2026

Opens in a new windowBest Western Seven Seas
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
$239 nightly
The price is $274 total per night from Oct 30 to Oct 31
$274 total
Oct 30 - Oct 31
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 3 restaurants. Family-friendly amenities include mini golf and kid-friendly dining, along with ...
Opens in a new windowParadise Point Resort & Spa
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Oct 25 to Oct 26
$211 total
Oct 25 - Oct 26
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center and free WiFi in public ...
Opens in a new windowWyndham San Diego Bayside
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
$276 nightly
The price is $320 total per night from Oct 25 to Oct 26
$320 total
Oct 25 - Oct 26
Total with taxes and fees
This smoke-free hotel includes 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in ...
Opens in a new windowManchester Grand Hyatt San Diego
California Suites Hotel

California Suites Hotel

2 out of 5
5415 Clairemont Mesa Blvd San Diego CA
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $102 total per night from Oct 4 to Oct 5
$102 total
Oct 4 - Oct 5
Total with taxes and fees
This hotel features an outdoor pool and a hot tub. Traveling for business? Take advantage of the free WiFi in public areas, express check-out, and conference ...
Opens in a new windowCalifornia Suites Hotel
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
$237 nightly
The price is $274 total per night from Oct 25 to Oct 26
$274 total
Oct 25 - Oct 26
Total with taxes and fees
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy the 24-hour gym and perks like free WiFi. There's a bar/lounge ...
Opens in a new windowHard Rock Hotel San Diego
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
$183 nightly
The price is $210 total per night from Oct 25 to Oct 26
$210 total
Oct 25 - Oct 26
Total with taxes and fees
A marina, 5 restaurants, and 3 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi ...
Opens in a new windowSheraton San Diego Resort
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap South San Diego hotels

The Rambler Hotel

The Rambler Hotel

225 Bay Blvd Chula Vista CA
$96 nightly
The price is $112 total per night from Oct 29 to Oct 30
$112 total
Oct 29 - Oct 30
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent South San Diego hotel reviews by fellow wanderers

Handlery Hotel

Handlery Hotel

5 out of 5
Posted 3 hours ago
Travelocity Verified Review
"All good except they need to stock the vending machines"
A verified traveler stayed at Handlery Hotel
Handlery Hotel

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