Book Hotels in South San Diego, CA

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Top South San Diego hotels

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
$237 nightly
The price is $274 total per night from Apr 5 to Apr 6
$274 total
Apr 5 - Apr 6
Total with taxes and fees
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free ...
They charged $100 more than it was showing on hotels.com. Said it is mandatory resort fees. We were given a handicap room which was fine until showering. The floor design completely floods the entire bathroom floor. Front desk staff were rude when we asked about the extra charges. We will not stay ...

Reviewed on Mar 17, 2026

Opens in a new windowHard Rock Hotel San Diego
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $150 total per night from Apr 5 to Apr 6
$150 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Expensive parking!

Reviewed on Mar 16, 2026

Opens in a new windowThe DEXTRO Little Italy, BW Premier Collection
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
Fully refundableReserve now, pay when you stay
$236 nightly
The price is $274 total per night from Apr 2 to Apr 3
$274 total
Apr 2 - Apr 3
Total with taxes and fees
This hotel features 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Perfect service

Reviewed on Mar 13, 2026

Opens in a new windowManchester Grand Hyatt San Diego
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
$273 nightly
The price is $314 total per night from Apr 5 to Apr 6
$314 total
Apr 5 - Apr 6
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 2 restaurants. Family-friendly amenities include mini golf and kid-friendly dining, along with ...
Wonderful place to stay. There were little things here and there (like a tear in our couch) that made me take a 2nd look. But besides that, it was a great trip. We will visit again.

Reviewed on Mar 17, 2026

Opens in a new windowParadise Point Resort & Spa
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $139 total per night from Apr 7 to Apr 8
$139 total
Apr 7 - Apr 8
Total with taxes and fees
A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
Appreciated the fitness room! Very close to convention center, super friendly staff.

Reviewed on Mar 17, 2026

Opens in a new windowThe Sofia Hotel
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
Fully refundableReserve now, pay when you stay
$182 nightly
The price is $211 total per night from Mar 19 to Mar 20
$211 total
Mar 19 - Mar 20
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Clean

Reviewed on Mar 17, 2026

Opens in a new windowWyndham San Diego Bayside
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $126 total per night from Apr 5 to Apr 6
$126 total
Apr 5 - Apr 6
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
Nice hotel

Reviewed on Mar 16, 2026

Opens in a new windowHandlery Hotel
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $123 total per night from Mar 23 to Mar 24
$123 total
Mar 23 - Mar 24
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...
This hotel fits our need for a clean, comfortable and convenient stop when we are in San Diego. The staff is accommodating and our room was pleasant and roomy. We have stayed here previously and this was by far our best experience with a large accessible room. We unloaded the car directly into our ...

Reviewed on Mar 17, 2026

Opens in a new windowDays Inn by Wyndham San Diego Hotel Circle
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $87 total per night from Mar 29 to Mar 30
$87 total
Mar 29 - Mar 30
Total with taxes and fees
2 hot tubs, an outdoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi ...
The receptionist was very helpful

Reviewed on Mar 16, 2026

Opens in a new windowBest Western Seven Seas
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap South San Diego hotels

The Rambler Hotel

The Rambler Hotel

225 Bay Blvd Chula Vista CA
$119 nightly
The price is $138 total per night from Mar 25 to Mar 26
$138 total
Mar 25 - Mar 26
Total with taxes and fees
9/10 Wonderful! (2,082 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent South San Diego hotel reviews by fellow wanderers

Sheraton San Diego Resort

Sheraton San Diego Resort

5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Our room was clean and spacious. The bathroom was also clean and spacious and everything worked very well. I was in the hallway and asked staff for extra towels and she gladly provided what we needed. I would definitely stay here again!"
A verified traveler stayed at Sheraton San Diego Resort
Sheraton San Diego Resort

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