Book Hotels in South San Diego, CA

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Top South San Diego hotels

Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

3 out of 5
3888 Greenwood St San Diego CA
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $155 total per night from Feb 15 to Feb 16
$155 total
Feb 15 - Feb 16
Total with taxes and fees
This hotel features an outdoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the hot tub and free buffet breakfast ...
Great

Reviewed on Feb 2, 2026

Opens in a new windowHampton Inn & Suites by Hilton San Diego SeaWorld
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $160 total per night from Feb 24 to Feb 25
$160 total
Feb 24 - Feb 25
Total with taxes and fees
A marina, a gym, and a restaurant are all featured at this traditional hotel. Traveling on business? Take advantage of the free WiFi in public areas and free ...
Always fabulous! That’s a great staff here, the views are wonderful, the restaurant is great, the bar is fun and the bartenders are wonderful. There’s the sweetest lady in the mornings that helps with breakfast and her name is Mariam and she is the best. I always love my stay here.

Reviewed on Feb 2, 2026

Opens in a new windowBay Club Hotel & Marina
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
$237 nightly
The price is $274 total per night from Feb 6 to Feb 7
$274 total
Feb 6 - Feb 7
Total with taxes and fees
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free ...
Very clean hotel. I was always seeing someone cleaning.

Reviewed on Feb 2, 2026

Opens in a new windowHard Rock Hotel San Diego
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $135 total per night from Feb 22 to Feb 23
$135 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Room was clean and spacious. The staff was nice and easy to walk to little Italy. Would definitely stay again

Reviewed on Jan 29, 2026

Opens in a new windowThe DEXTRO Little Italy, BW Premier Collection
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $206 total per night from Feb 22 to Feb 23
$206 total
Feb 22 - Feb 23
Total with taxes and fees
A marina, 2 outdoor pools, and 2 hot tubs are all featured at this smoke-free hotel. If you want to take your pet along, this pet-friendly property offers everything ...
Amazing location. Beautiful grounds and so close to everything. We loved our garden room looking out to the tropical pool.

Reviewed on Jan 28, 2026

Opens in a new windowThe Dana on Mission Bay
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
$198 nightly
The price is $227 total per night from Feb 22 to Feb 23
$227 total
Feb 22 - Feb 23
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 2 restaurants. Family-friendly amenities include mini golf and kid-friendly dining, along with ...
Enjoyed the property and environment.

Reviewed on Feb 1, 2026

Opens in a new windowParadise Point Resort & Spa
San Diego Mission Bay Resort

San Diego Mission Bay Resort

4 out of 5
1775 E Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
$230 nightly
The price is $265 total per night from Feb 22 to Feb 23
$265 total
Feb 22 - Feb 23
Total with taxes and fees
A full-service spa, 2 restaurants, and 5 outdoor tennis courts are all featured at this Mediterranean resort. There's fun for all ages with a children's pool ...
Great room, great amenities, the resort was so nice.

Reviewed on Jan 21, 2026

Opens in a new windowSan Diego Mission Bay Resort
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
Fully refundableReserve now, pay when you stay
$170 nightly
The price is $197 total per night from Feb 16 to Feb 17
$197 total
Feb 16 - Feb 17
Total with taxes and fees
A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
Fairly good location

Reviewed on Feb 3, 2026

Opens in a new windowThe Sofia Hotel
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $87 total per night from Feb 8 to Feb 9
$87 total
Feb 8 - Feb 9
Total with taxes and fees
2 hot tubs, an outdoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi ...
The Best Western than seven seas is special to me because I stayed there as a child with my parents and grandparents. It is old motor in style San Diego or best Western in its old form.. The staff is great and it has a nice pool and Jacuzzi.. It is very affordable..

Reviewed on Feb 2, 2026

Opens in a new windowBest Western Seven Seas
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap South San Diego hotels

The Rambler

The Rambler

225 Bay Blvd Chula Vista CA
$105 nightly
The price is $122 total per night from Feb 5 to Feb 6
$122 total
Feb 5 - Feb 6
Total with taxes and fees
9/10 Wonderful! (2,040 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent South San Diego hotel reviews by fellow wanderers

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Very clean hotel. I was always seeing someone cleaning."
A verified traveler stayed at Hard Rock Hotel San Diego
Hard Rock Hotel San Diego

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