Book Hotels in South San Diego, CA
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Top South San Diego hotels

Holiday Inn Express San Diego South - Chula Vista by IHG
632 E Street Chula Vista CA
Fully refundable
$152 nightly
The price is $167 total per night from Jul 6 to Jul 7
$167 total
Jul 6 - Jul 7
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...
"Breakfast was good room was okay clean and staff was amazing"
Reviewed on Jun 8, 2026

Manchester Grand Hyatt San Diego
1 Market Pl San Diego CA
Fully refundableReserve now, pay when you stay
$306 nightly
The price is $355 total per night from Jul 1 to Jul 2
$355 total
Jul 1 - Jul 2
Total with taxes and fees
This hotel features 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
"A beautiful property i. a great location"
Reviewed on Jun 8, 2026

Hard Rock Hotel San Diego
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
$193 nightly
The price is $224 total per night from Jun 14 to Jun 15
$224 total
Jun 14 - Jun 15
Total with taxes and fees
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free ...
"The staff were very polite, accommodating and efficient. The hotel is beautiful and the room was very clean."
Reviewed on Jun 8, 2026

The Sofia Hotel
150 W Broadway San Diego CA
Fully refundableReserve now, pay when you stay
$171 nightly
The price is $198 total per night from Jun 29 to Jun 30
$198 total
Jun 29 - Jun 30
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
"Great place!"
Reviewed on Jun 8, 2026

San Diego Mission Bay Resort
1775 E Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
$335 nightly
The price is $385 total per night from Jun 14 to Jun 15
$385 total
Jun 14 - Jun 15
Total with taxes and fees
A full-service spa, 2 restaurants, and 5 outdoor tennis courts are all featured at this Mediterranean resort. There's fun for all ages with a children's pool ...
"This is my first time staying at this resort. My family and I enjoyed it very much. We loved all the amenities, restaurants, and excellent staff. They all went far and beyond to make sure we had an excellently pleasant stay. From front desk, pool, restaurants, and throughout. Definitely coming ..."
Reviewed on Jun 7, 2026

Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
Fully refundableReserve now, pay when you stay
$182 nightly
The price is $211 total per night from Jun 14 to Jun 15
$211 total
Jun 14 - Jun 15
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center and free WiFi in public ...
"The hotel is located at a prime location with wonderful bay view but everything inside the hotel feels dirty, certainly not a 4-5 stars hotel like I have requested on the Expedia web site. The staff at least was understanding and nice enough to move us to another building with better layout and bed. ..."
Reviewed on Jun 8, 2026

Best Western Seven Seas
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $113 total per night from Jun 14 to Jun 15
$113 total
Jun 14 - Jun 15
Total with taxes and fees
2 hot tubs, an outdoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi ...
"Definitely not as nice as the photos. I stayed at Best Western Seven Seas and it is definitely not as nice as the photos show. The bathroom vent and wall had black dust balls or mold on them. The corner at the bottom of the wall also had lifting wallpaper with a stain that looked like mildew. To ..."
Reviewed on Jun 8, 2026

Days Inn by Wyndham San Diego Hotel Circle
543 Hotel Circle S San Diego CA
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $113 total per night from Jun 15 to Jun 16
$113 total
Jun 15 - Jun 16
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...
"First of all the rooms are extremely humid so if you have any expensive leather, I wouldn’t put it in the room or electronics. We had to keep those in the car. The humidity would’ve ruined our things. The location was a bit dicey as well. I would’ve stayed on hotel Circle N. Not Hotel Circle S. The ..."
Reviewed on Jun 8, 2026

California Suites Hotel
5415 Clairemont Mesa Blvd San Diego CA
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $114 total per night from Jun 9 to Jun 10
$114 total
Jun 9 - Jun 10
Total with taxes and fees
This hotel features an outdoor pool and a hot tub. Traveling for business? Take advantage of the free WiFi in public areas, express check-out, and conference ...
"Table in room was wobbly (had to be careful not to spill my drink on myself when at the table), phone in room was not working (in case I needed to reach out to office personnel), remote to A/C unit did not work (mo battery cover..tape used to hold batteries in place), no microwave or coffee maker ..."
Reviewed on Jun 8, 2026
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap South San Diego hotels

The Rambler Hotel
225 Bay Blvd Chula Vista CA
$109 nightly
The price is $126 total per night from Jun 9 to Jun 10
$126 total
Jun 9 - Jun 10
Total with taxes and fees
9/10 Wonderful! (2,158 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in South San Diego with star-rating
Check South San Diego Hotels by Star Rating

5 Star Hotels
5 properties
Recent South San Diego hotel reviews by fellow wanderers

Wyndham San Diego Bayside
3 out of 5
Posted less than an hour ago
Travelocity Verified Review
"The hotel is located at a prime location with wonderful bay view but everything inside the hotel feels dirty, certainly not a 4-5 stars hotel like I have requested on the Expedia web site. The staff at least was understanding and nice enough to move us to another building with better layout and bed. We really loved the location and the bayside view but without this, we may not have considered the hotel at all since it is not well maintained inside, you could see pile of dust in certain areas, i.e. that must not have been cleaned for years. I have yet to verify the charges as it seems higher than what we booked for. Sally restaurant in the area had such an attitude, made you wait for long time at the entrance, then a white lady came forward and said this is for breakfast buffet and no other menu offered, then she checked me out from head to toe with a question in her eyes "can you really afford this?", that was not a good start for a morning. Oh by the way, the lady and another white guy saw my mom waiting in her wheelchair at the stairs, yet still offered no accessible way for her to enter the restaurant. We left the restaurant and decided not to tolerate any of these attitude during a short weekend getaway. I also chose not to send a complaint letter to the restaurant’s management or hotel; I don’t want to jeopardize anyone’s job."
A verified traveler stayed at Wyndham San Diego Bayside
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