Book Hotels in South San Diego, CA

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Sep 4 - Sep 6
Next weekend
Sep 11 - Sep 13

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top South San Diego hotels

Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
$166 nightly
The price is $191 total per night from Sep 7 to Sep 8
$191 total
Sep 7 - Sep 8
Total with taxes and fees
A marina, a gym, and a restaurant are all featured at this traditional hotel. Traveling on business? Take advantage of the free WiFi in public areas and free ...
"Excellent."

Reviewed on Sep 1, 2026

Opens in a new windowBay Club Hotel & Marina
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
Fully refundableReserve now, pay when you stay
$246 nightly
The price is $285 total per night from Sep 7 to Sep 8
$285 total
Sep 7 - Sep 8
Total with taxes and fees
This smoke-free hotel includes 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in ...
"The room appeared to be newly refurbished and the bathroom was nice. The main lobby looks amazing."

Reviewed on Sep 1, 2026

Opens in a new windowManchester Grand Hyatt San Diego
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
$221 nightly
The price is $256 total per night from Sep 2 to Sep 3
$256 total
Sep 2 - Sep 3
Total with taxes and fees
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy the 24-hour gym and perks like free WiFi. There's a bar/lounge ...
"Room was clean enough, some leftover stains on the sink when we walked in. Shower splashes underneath shower door and spills out. Toilet needs to be pushed a little bit back so it doesn’t keep refilling."

Reviewed on Sep 1, 2026

Opens in a new windowHard Rock Hotel San Diego
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
$186 nightly
The price is $213 total per night from Sep 2 to Sep 3
$213 total
Sep 2 - Sep 3
Total with taxes and fees
A marina, 2 outdoor pools, and 2 hot tubs are all featured at this smoke-free hotel. If you want to take your pet along, this pet-friendly property offers everything ...
"It was a great location with a nice boardwalk! The 2 pools were great - we felt like we were in Hawaii!! The restaurant was excellent!"

Reviewed on Aug 31, 2026

Opens in a new windowThe Dana on Mission Bay
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
Fully refundableReserve now, pay when you stay
$182 nightly
The price is $211 total per night from Sep 3 to Sep 4
$211 total
Sep 3 - Sep 4
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center and free WiFi in public ...
"This place is in a great location. The free coffee is nice in the morning. The workout rooms are great, and the pool."

Reviewed on Sep 1, 2026

Opens in a new windowWyndham San Diego Bayside
Gaylord Pacific Resort & Convention Center

Gaylord Pacific Resort & Convention Center

4 out of 5
1000 H Street Chula Vista CA
Fully refundableReserve now, pay when you stay
$314 nightly
The price is $364 total per night from Sep 7 to Sep 8
$364 total
Sep 7 - Sep 8
Total with taxes and fees
A full-service spa, 8 restaurants, and 3 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
Opens in a new windowGaylord Pacific Resort & Convention Center
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
$254 nightly
The price is $292 total per night from Sep 7 to Sep 8
$292 total
Sep 7 - Sep 8
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 3 restaurants. Family-friendly amenities include mini golf and kid-friendly dining, along with ...
Opens in a new windowParadise Point Resort & Spa
California Suites Hotel

California Suites Hotel

2 out of 5
5415 Clairemont Mesa Blvd San Diego CA
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $102 total per night from Sep 20 to Sep 21
$102 total
Sep 20 - Sep 21
Total with taxes and fees
This hotel features an outdoor pool and a hot tub. Traveling for business? Take advantage of the free WiFi in public areas, express check-out, and conference ...
Opens in a new windowCalifornia Suites Hotel
Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark

4 out of 5
675 L St San Diego CA
Fully refundableReserve now, pay when you stay
$206 nightly
The price is $239 total per night from Sep 3 to Sep 4
$239 total
Sep 3 - Sep 4
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Opens in a new windowOmni San Diego Hotel at the Ballpark
Don't see what you're looking for?
See all available properties in South San Diego
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap South San Diego hotels

The Rambler Hotel

The Rambler Hotel

225 Bay Blvd Chula Vista CA
$112 nightly
The price is $140 total per night from Sep 15 to Sep 16
$140 total
Sep 15 - Sep 16
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent South San Diego hotel reviews by fellow wanderers

Bay Club Hotel & Marina

Bay Club Hotel & Marina

5 out of 5
Posted 10 hours ago
Travelocity Verified Review
"Excellent."
A verified traveler stayed at Bay Club Hotel & Marina
Bay Club Hotel & Marina

Explore More Ways to Travel with Travelocity