Find a Hotel in Otay Mesa
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Top hotels in Otay Mesa
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2296 Niels Bohr Ct, San Diego, CA
Free Cancellation
1.96 mi from Otay Mesa
$111 nightly
The price is $126 total per night
$126 total
Aug 10 - Aug 11
Total includes taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included
Handlery Hotel
950 Hotel Cir N, San Diego, CA
18.06 mi from Otay Mesa
$135 nightly
The price is $155 total per night
$155 total
Jul 13 - Jul 14
Total includes taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the gym and visit the 2 bars/lounges and poolside bar for drinks.
Pool
Hot Tub
Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
15.97 mi from Otay Mesa
$177 nightly
The price is $205 total per night
$205 total
Jul 20 - Jul 21
Total includes taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, express check-out, and free airport shuttle. There's a bar/lounge on site, and concierge services and free newspapers are also provided.
Pool
Free airport shuttle
Manchester Grand Hyatt San Diego
1 Market Pl, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
15.38 mi from Otay Mesa
$222 nightly
The price is $257 total per night
$257 total
Jul 20 - Jul 21
Total includes taxes and fees
This eco-certified hotel includes 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Enjoy the hot tub and visit the 3 bars/lounges and poolside bar for drinks.
Pool
Hot Tub
Marriott Marquis San Diego Marina
333 W Harbor Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
15.21 mi from Otay Mesa
$246 nightly
The price is $286 total per night
$286 total
Jul 28 - Jul 29
Total includes taxes and fees
This smoke-free hotel features a full-service spa, a marina, and 5 restaurants. Families will appreciate the children's pool and onsite laundry facilities. Enjoy the 2 outdoor pools and perks like free WiFi.
Pool
Hot Tub
The Little Italy Hotel Downtown San Diego
1646 Front St, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
15.84 mi from Otay Mesa
$119 nightly
The price is $138 total per night
$138 total
Aug 4 - Aug 5
Total includes taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Self parking is offered and multilingual staff can provide around-the-clock assistance.
Pet friendly
Free WiFi
Hilton San Diego Bayfront
1 Park Blvd, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
14.72 mi from Otay Mesa
$197 nightly
The price is $229 total per night
$229 total
Aug 3 - Aug 4
Total includes taxes and fees
A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Bring the family and enjoy the children's pool and kid-friendly dining. Relax with a drink at one of the 2 bars/lounges and get perks like free WiFi.
Pool
Hot Tub
Hotel del Coronado, Curio Collection by Hilton
1500 Orange Ave, Coronado, CA
Free Cancellation
Reserve now, pay when you stay
14.54 mi from Otay Mesa
$402 nightly
The price is $446 total per night
$446 total
Jul 20 - Jul 21
Total includes taxes and fees
A private beach, 6 restaurants, and an outdoor pool are all featured at this Victorian resort. Relax with sun loungers and beach umbrellas, and cool off with a drink at the beachside bar. Families will appreciate the children's club, picnic area, and babysitting.
On private beach
Pool
Hampton Inn San Diego/Mission Valley
2151 Hotel Circle South, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
18.36 mi from Otay Mesa
$139 nightly
The price is $160 total per night
$160 total
Jul 13 - Jul 14
Total includes taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the free on-the-go breakfast each morning.
Pool
Breakfast included
Alma San Diego Downtown, a Tribute Portfolio Hotel
1047 5th Ave, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
15.32 mi from Otay Mesa
$136 nightly
The price is $157 total per night
$157 total
Jul 21 - Jul 22
Total includes taxes and fees
This boutique hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and valet parking. Enjoy the a rooftop terrace and visit the 2 bars/lounges and poolside bar for drinks.
Pool
Pet friendly
The Dana on Mission Bay
1710 W Mission Bay Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
20.96 mi from Otay Mesa
$191 nightly
The price is $220 total per night
$220 total
Aug 10 - Aug 11
Total includes taxes and fees
A marina, 2 outdoor pools, and 2 hot tubs are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and visit the 2 poolside bars and bar/lounge for drinks.
Pool
Hot Tub
Kings Inn San Diego
1333 Hotel Cir S, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
18.07 mi from Otay Mesa
$102 nightly
The price is $118 total per night
$118 total
Aug 4 - Aug 5
Total includes taxes and fees
This Art Deco hotel includes 2 restaurants, an outdoor pool, and a hot tub. Enjoy the gym and perks like free WiFi. A bar/lounge, a 24-hour front desk, and a coffee shop are also provided.
Pool
Hot Tub
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Otay Mesa Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Otay Mesa area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Otay Mesa to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Otay Mesa are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Otay Mesa hotels essential information
Accommodation | 4,597 hotels |
|---|---|
Lowest Price | $118 |
Highest Price | $446 |
Popular hotels | Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG, Handlery Hotel, Wyndham San Diego Bayside, Manchester Grand Hyatt San Diego, Marriott Marquis San Diego Marina, The Little Italy Hotel Downtown San Diego, Hilton San Diego Bayfront, Hotel del Coronado, Curio Collection by Hilton, Hampton Inn San Diego/Mission Valley, Alma San Diego Downtown, a Tribute Portfolio Hotel, The Dana on Mission Bay, Kings Inn San Diego |
Recent Otay Mesa hotel reviews by fellow wanderers
Manchester Grand Hyatt San Diego
5 out of 5
Posted 15 hours ago
Travelocity Verified Review
"Wakable and nice staff."
A verified traveler stayed at Manchester Grand Hyatt San Diego
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