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Top hotels in Otay Mesa

Sheraton San Diego Resort
"Never going back. Worse experience I have had at a Sheraton. Staff were unresponsive and dismissive, if you could even find them at all. Whoever manages this location is either incompetent or unable to lead effectively."
Reviewed on Nov 10, 2026

Wyndham San Diego Bayside
"Great location! Great views (on 10th floor, bayside). Great breakfast in the adjoining Claim Jumper. Room was dated but clean. Would stay here again"
Reviewed on Nov 10, 2026

Handlery Hotel
"This property had such a cool, vintage California feel. Even though it is an old building, things were well kept up and clean. The beds were comfortable and I was glad the room had a coffee maker and a safe. The restaurant on site was good and all employees I interacted with were friendly. Parking ..."
Reviewed on Nov 10, 2026

Days Inn by Wyndham San Diego Hotel Circle
"The room was very clean and newly remodeled. Unfortunately, there was too much construction going on with a new room install. Too loud and congested around the parking lot."
Reviewed on Nov 11, 2026

The Alcala Hotel Mission Valley/Seaworld
"So idk why this hotel has such high reviews. The rooms are terrible. Lighting sucks, no table to eat. One chair to sit outside the beds. Has a bathtub, but no plug to give kids a bath. Had to use a washcloth to plug it. Everything is so loud. The upstairs people were running around all night and ..."
Reviewed on Nov 10, 2026

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Hard Rock Hotel San Diego

Paradise Point Resort & Spa

Best Western Seven Seas
Otay Mesa Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Otay Mesa area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Otay Mesa to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Otay Mesa are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Otay Mesa hotel reviews by fellow wanderers

Wyndham San Diego Bayside
"We have stayed here before. I had upgraded our room and was under the impression we would have a balcony. We only had a small ledge. Disappointed because we really enjoyed sitting on the balcony on our previous trip. So, lesson learned, Next time I will doublecheck to make sure we have a full balcony. We were also right next to the elevator and heard the dinging bell from the elevator late into the night and early morning."
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