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Hotels near Otay Mesa

$189
Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown

4.0 out of 5.0 601 Pacific Hwy, San Diego, CA
4.6/5
(13 Reviews)
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, express check-in, and valet parking. Enjoy the 24-hour fitness center and free on-the-go breakfast each morning.
$127
Courtyard by Marriott San Diego Airport/Liberty Station

Courtyard by Marriott San Diego Airport/Liberty Station

3.0 out of 5.0 2592 Laning Rd, San Diego, CA
4.5/5
(8 Reviews)
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. There's a 24-hour fitness center on site, and laundry facilities and free newspapers are also offered.
$166
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4.0 out of 5.0 207 5th Ave, San Diego, CA
4.5/5
(33 Reviews)
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. 2 coffee shops/cafés offer dining options, while a poolside bar and a 24-hour fitness center are also on site.
$110
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

3.0 out of 5.0 800 Bay Marina Dr, National City, CA
4.4/5
(27 Reviews)
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the fitness center and perks like free self parking.
$135
Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina

3.0 out of 5.0 2051 Shelter Island Dr, San Diego, CA
4.4/5
(39 Reviews)
A marina, 2 outdoor pools, and 2 outdoor tennis courts are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 6 conference rooms, as well as the 24-hour business center and free WiFi in public areas. There's a fitness center on site, and laundry facilities and concierge services are also offered.
$85
Holiday Inn Express Hotel & Suites San Diego Otay Mesa

Holiday Inn Express Hotel & Suites San Diego Otay Mesa

2.5 out of 5.0 2296 Niels Bohr Ct, San Diego, CA
4.2/5
(10 Reviews)
This hotel features an outdoor pool and a fitness center. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
$224
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4.0 out of 5.0 1404 Vacation Rd, San Diego, CA
4.1/5
(39 Reviews)
This smoke-free resort features a full-service spa, a marina, and 3 restaurants. Families will appreciate the mini golf, onsite laundry facilities, and supervised childcare. Traveling on business? Take advantage of the business center, conference center, and conference space.
$135
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4.0 out of 5.0 1355 N Harbor Drive, San Diego, CA
4/5
(65 Reviews)
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a fitness center. Traveling on business? Take advantage of the business center, express check-out, and free airport shuttle. Unwind with a drink at the bar/lounge and enjoy perks like a free cruise terminal shuttle.
$155
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5.0 1710 W Mission Bay Dr, San Diego, CA
3.9/5
(245 Reviews)
This smoke-free hotel features a marina, 2 outdoor pools, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the fitness center and unwind at the poolside bar and bar/lounge.
$99
Hilton Garden Inn San Diego Mission Valley Stadium

Hilton Garden Inn San Diego Mission Valley Stadium

3.0 out of 5.0 3805 Murphy Canyon Rd, San Diego, CA
3.8/5
(20 Reviews)
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 2 conference rooms, as well as the business center and free WiFi in public areas. There's a fitness center on site, and laundry facilities and free newspapers are also offered.
$80
Best Western Seven Seas

Best Western Seven Seas

3.0 out of 5.0 411 Hotel Circle South, San Diego, CA
3.7/5
(95 Reviews)
2 spa tubs, an outdoor pool, and a fitness center are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy a meal from the a restaurant and perks like free self parking.
$76
Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa

2.5 out of 5.0 2351 Otay Center Dr, San Diego, CA
3.7/5
(20 Reviews)
This hotel features an outdoor pool and a spa tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
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How much is a hotel room in Otay Mesa?

Hotels in Otay Mesa start at $76 per night. Prices and availability subject to change. Additional terms may apply.


Otay Mesa Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Otay Mesa area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Otay Mesa to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Otay Mesa are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Otay Mesa Hotel Reviews By Fellow Wanderers

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.