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Hotels near Otay Mesa

Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel

Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel

2.5 out of 5
2296 Niels Bohr Ct, San Diego, CA
Free Cancellation
1.96 mi from Otay Mesa
The price is $139 per night
$139
per night
Jun 11 - Jun 12
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
Free Cancellation
15.38 mi from Otay Mesa
The price is $212 per night
$212
per night
Jul 6 - Jul 7
This eco-certified aparthotel includes 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. There's a poolside bar on site, and laundry facilities and concierge services are also provided.
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive, San Diego, CA
Free Cancellation
15.97 mi from Otay Mesa
The price is $165 per night
$165
per night
Jun 27 - Jun 28
This smoke-free aparthotel includes 2 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, express check-out, and free airport shuttle. There's a bar/lounge on site, and concierge services and free newspapers are also provided.
San Diego Mission Bay Resort

San Diego Mission Bay Resort

4 out of 5
1775 E Mission Bay Dr, San Diego, CA
20.44 mi from Otay Mesa
The price is $339 per night
$339
per night
Jun 13 - Jun 14
A full-service spa, 2 restaurants, and 5 outdoor tennis courts are all featured at this Mediterranean aparthotel. There's fun for all ages with a children's pool and an arcade/game room, and families will appreciate the picnic area. Enjoy the outdoor pool and perks like free WiFi.
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
20.96 mi from Otay Mesa
The price is $191 per night
$191
per night
Jun 11 - Jun 12
A marina, 2 outdoor pools, and 2 spa tubs are all featured at this smoke-free aparthotel. Traveling on business? Take advantage of the 13 conference rooms, as well as the business center and free WiFi in public areas. Enjoy the gym and visit the 2 poolside bars and bar/lounge for drinks.
Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld

3 out of 5
3737 Sports Arena Blvd, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
19.47 mi from Otay Mesa
The price is $119 per night
$119
per night
Jun 11 - Jun 12
A gym, self parking, and laundry facilities are featured at this aparthotel. WiFi in public areas is free. Traveling on business? Take advantage of the 3 conference rooms, business center, and express check-in.
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
21.43 mi from Otay Mesa
The price is $277 per night
$277
per night
Jun 11 - Jun 12
This smoke-free aparthotel features a full-service spa, a marina, and 3 restaurants. Family-friendly amenities include mini golf and kid-friendly dining, along with kayaking. Enjoy the 5 outdoor pools and perks like free WiFi.
Loews Coronado Bay Resort

Loews Coronado Bay Resort

4 out of 5
4000 Coronado Bay Rd, Coronado, CA
10.67 mi from Otay Mesa
The price is $269 per night
$269
per night
Jun 15 - Jun 16
A full-service spa, a marina, and 3 outdoor pools are all featured at this hotel. Take the free beach shuttle and relax with sun loungers and beach umbrellas. Families will appreciate the children's pool, onsite laundry facilities, and in-room childcare.
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
14.9 mi from Otay Mesa
The price is $209 per night
$209
per night
Jun 21 - Jun 22
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free aparthotel. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free WiFi. Enjoy the 24-hour gym and unwind at the bar/lounge and poolside bar.
Sheraton San Diego Hotel and Marina

Sheraton San Diego Hotel and Marina

4 out of 5
1380 Harbor Island Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
17.44 mi from Otay Mesa
The price is $229 per night
$229
per night
Jul 6 - Jul 7
A marina, 6 restaurants, and 3 outdoor pools are all featured at this smoke-free aparthotel. Traveling on business? Take advantage of the 52 conference rooms, 24-hour business center, and free airport shuttle. You'll find 2 coffee shops/cafes and 2 spa tubs on site, along with a poolside bar to unwind.
The Atwood Hotel San Diego - SeaWorld/Zoo

The Atwood Hotel San Diego - SeaWorld/Zoo

3 out of 5
1201 Hotel Circle South, Mission Valley, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
18.05 mi from Otay Mesa
The price is $142 per night
$142
per night
Jun 11 - Jun 12
This aparthotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the spa tub and perks like free self parking and free WiFi. A coffee shop, a snack bar/deli, and a picnic area are also on offer.
DoubleTree by Hilton San Diego - Hotel Circle

DoubleTree by Hilton San Diego - Hotel Circle

4 out of 5
1515 Hotel Cir S, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
18.14 mi from Otay Mesa
The price is $168 per night
$168
per night
Jun 11 - Jun 12
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. There's a 24-hour gym on site, and a 24-hour front desk and a terrace are also provided.
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Otay Mesa Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Otay Mesa area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Otay Mesa to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Otay Mesa are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Otay Mesa hotels essential information

Number of reviews
Accommodation
3,561 hotels
Lowest Price
$119
Highest Price
$339
Popular hotels
Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel, Manchester Grand Hyatt San Diego, Wyndham San Diego Bayside, San Diego Mission Bay Resort, The Dana on Mission Bay, Wyndham Garden San Diego Near SeaWorld, Paradise Point Resort & Spa, Loews Coronado Bay Resort, Hard Rock Hotel San Diego, Sheraton San Diego Hotel and Marina, The Atwood Hotel San Diego - SeaWorld/Zoo, DoubleTree by Hilton San Diego - Hotel Circle

Recent Otay Mesa hotel reviews by fellow wanderers

  • The Dana on Mission Bay

    The Dana on Mission Bay

    5 out of 5
    Posted 22 hours ago
    Travelocity Verified Review
    "Beautiful fragrant grounds. Loved strolling around the marina. I only wish there had been more dining options within walking distance."
    A verified traveler from Moreno Valley stayed at The Dana on Mission Bay
    The Dana on Mission Bay

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