Book Cheap Hotels in San Diego Santa Fe Depot, CA

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Top San Diego Santa Fe Depot hotels

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Free Cancellation
Reserve now, pay when you stay
0.8 mi from San Diego Santa Fe Depot
$245 nightly
The price is $284 total per night
$284 total
May 10 - May 11
Total with taxes and fees
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free WiFi. Enjoy the 24-hour gym and unwind at the bar/lounge and poolside bar.
Pool
Free WiFi
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
Free Cancellation
Reserve now, pay when you stay
0.28 mi from San Diego Santa Fe Depot
$146 nightly
The price is $169 total per night
$169 total
May 11 - May 12
Total with taxes and fees
A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Self parking, a coffee shop, and a lobby fireplace are also offered.
Pet friendly
Free WiFi
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
Free Cancellation
0.54 mi from San Diego Santa Fe Depot
$119 nightly
The price is $138 total per night
$138 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's a 24-hour gym on site, and a 24-hour front desk and express check-out are also provided.
Pool
Free WiFi
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Free Cancellation
Reserve now, pay when you stay
5.75 mi from San Diego Santa Fe Depot
$243 nightly
The price is $279 total per night
$279 total
May 10 - May 11
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 2 restaurants. Family-friendly amenities include mini golf and kid-friendly dining, along with kayaking. Enjoy the 5 outdoor pools and perks like free WiFi.
Pool
Hot Tub
Hotel del Coronado, Curio Collection by Hilton

Hotel del Coronado, Curio Collection by Hilton

4 out of 5
1500 Orange Ave Coronado CA
Free Cancellation
Reserve now, pay when you stay
2.52 mi from San Diego Santa Fe Depot
$521 nightly
The price is $579 total per night
$579 total
May 11 - May 12
Total with taxes and fees
A private beach, 6 restaurants, and an outdoor pool are all featured at this Victorian resort. Relax with sun loungers and beach umbrellas, and cool off with a drink at the beachside bar. Families will appreciate the children's club, picnic area, and babysitting.
On private beach
Pool
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
Free Cancellation
Reserve now, pay when you stay
0.26 mi from San Diego Santa Fe Depot
$182 nightly
The price is $211 total per night
$211 total
May 10 - May 11
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. There's a bar/lounge on site, and concierge services and free newspapers are also provided.
Pool
Pet friendly
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Free Cancellation
Reserve now, pay when you stay
3.08 mi from San Diego Santa Fe Depot
$82 nightly
The price is $94 total per night
$94 total
May 7 - May 8
Total with taxes and fees
2 hot tubs, an outdoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy a meal from the a restaurant and perks like free self parking.
Pool
Hot Tub
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
3.06 mi from San Diego Santa Fe Depot
$122 nightly
The price is $140 total per night
$140 total
May 12 - May 13
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the gym and visit the 2 bars/lounges and poolside bar for drinks.
Pool
Hot Tub
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
Free Cancellation
Reserve now, pay when you stay
1.83 mi from San Diego Santa Fe Depot
$169 nightly
The price is $194 total per night
$194 total
May 25 - May 26
Total with taxes and fees
A marina, 5 restaurants, and 3 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Enjoy the 2 hot tubs, and relax with drinks at the bar/lounge and poolside bar.
Pool
Hot Tub
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Santa Fe Depot hotels essential information

Accommodation
3,925 hotels
Lowest Price
$94
Highest Price
$579
Popular hotels
Hard Rock Hotel San Diego, The Sofia Hotel, The DEXTRO Little Italy, BW Premier Collection, Paradise Point Resort & Spa, Hotel del Coronado, Curio Collection by Hilton, Wyndham San Diego Bayside, Best Western Seven Seas, Handlery Hotel, Sheraton San Diego Resort

Recent San Diego Santa Fe Depot hotel reviews by fellow wanderers

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Comfortable beds. Great location. Good amenities, but getting time for a renovation, especially the pool area and rooms. "
A verified traveler stayed at Hard Rock Hotel San Diego
Hard Rock Hotel San Diego

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