Book Cheap Hotels in San Diego Santa Fe Depot, CA
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Top San Diego Santa Fe Depot hotels

Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
0.26 mi from San Diego Santa Fe Depot
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, express check-out, and free airport shuttle. There's a bar/lounge on site, and concierge services and free newspapers are also provided.
Pool
Free airport shuttle

Marriott Marquis San Diego Marina
333 W Harbor Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
0.53 mi from San Diego Santa Fe Depot
This smoke-free hotel features a full-service spa, a marina, and 5 restaurants. Families will appreciate the children's pool and onsite laundry facilities. Enjoy the 2 outdoor pools and perks like free WiFi.
Pool
Hot Tub

Handlery Hotel
950 Hotel Cir N, San Diego, CA
3.06 mi from San Diego Santa Fe Depot
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the gym and visit the 2 bars/lounges and poolside bar for drinks.
Pool
Hot Tub

Manchester Grand Hyatt San Diego
1 Market Pl, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
0.43 mi from San Diego Santa Fe Depot
This eco-certified hotel includes 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Enjoy the hot tub and visit the 3 bars/lounges and poolside bar for drinks.
Pool
Hot Tub

Hyatt Regency Mission Bay Spa and Marina
1441 Quivira Rd, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
5.37 mi from San Diego Santa Fe Depot
This smoke-free hotel features a full-service spa, a marina, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Enjoy the 3 outdoor pools and gym, and unwind with a drink at the bar/lounge.
Pool
Hot Tub

Kings Inn San Diego
1333 Hotel Cir S, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
2.94 mi from San Diego Santa Fe Depot
This Art Deco hotel includes 2 restaurants, an outdoor pool, and a hot tub. Enjoy the gym and perks like free WiFi. A bar/lounge, a 24-hour front desk, and a coffee shop are also provided.
Pool
Hot Tub

The Little Italy Hotel Downtown San Diego
1646 Front St, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
0.48 mi from San Diego Santa Fe Depot
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Self parking is offered and multilingual staff can provide around-the-clock assistance.
Pet friendly
Free WiFi

Comfort Inn Sea World Area
3880 Greenwood St, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
3.43 mi from San Diego Santa Fe Depot
A gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like buffet breakfast and WiFi in public areas. There's a snack bar/deli and multilingual staff can provide around-the-clock assistance.
Breakfast included
Pet friendly

The Dana on Mission Bay
1710 W Mission Bay Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
5.25 mi from San Diego Santa Fe Depot
A marina, 2 outdoor pools, and 2 hot tubs are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and visit the 2 poolside bars and bar/lounge for drinks.
Pool
Hot Tub
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See all available properties in San Diego Santa Fe Depot
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
San Diego Santa Fe Depot hotels essential information
Accommodation | 3,665 hotels |
---|---|
Lowest Price | |
Highest Price | |
Popular hotels | Wyndham San Diego Bayside, Marriott Marquis San Diego Marina, Handlery Hotel, Manchester Grand Hyatt San Diego, Hyatt Regency Mission Bay Spa and Marina, Kings Inn San Diego, The Little Italy Hotel Downtown San Diego, Comfort Inn Sea World Area, The Dana on Mission Bay |
Recent San Diego Santa Fe Depot hotel reviews by fellow wanderers

Hyatt Regency Mission Bay Spa and Marina
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Very helpful staff and kid friendly! "
A verified traveler stayed at Hyatt Regency Mission Bay Spa and Marina
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