Explore the best 2025 4 Star Hotels Hotels in Little Italy

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Top Little Italy 4 Star hotels

Manchester Grand Hyatt San Diego

1 Market Pl, San Diego, CA

Free Cancellation

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This eco-certified hotel includes 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Enjoy the hot tub and visit the 3 bars/lounges and poolside bar for drinks.

Pool

Hot Tub

San Diego Marriott La Jolla

4240 La Jolla Village Dr, La Jolla, CA

Free Cancellation

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This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. A bar/lounge, a 24-hour front desk, and a coffee shop are also provided.

Pool

Pet friendly

Marriott Marquis San Diego Marina

333 W Harbor Dr, San Diego, CA

Free Cancellation

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This smoke-free hotel features a full-service spa, a marina, and 5 restaurants. Families will appreciate the children's pool and onsite laundry facilities. Enjoy the 2 outdoor pools and perks like free WiFi.

Pool

Hot Tub

Embassy Suites by Hilton San Diego Bay Downtown

601 Pacific Hwy, San Diego, CA

Free Cancellation

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This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, express check-in, and valet parking. Enjoy the gym and free buffet breakfast each morning.

DoubleTree by Hilton Hotel San Diego - Mission Valley

7450 Hazard Center Dr, San Diego, CA

Free Cancellation

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This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 20 conference rooms, free WiFi in public areas, and express check-out. There's an indoor pool on site, and laundry facilities and wedding services are also offered.

Sheraton Mission Valley San Diego Hotel

1433 Camino Del Rio S, San Diego, CA

Free Cancellation

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This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's a hot tub on site, and a 24-hour front desk and a terrace are also provided.

Pool

Hot Tub

Wyndham San Diego Bayside

1355 N Harbor Drive, San Diego, CA

Free Cancellation

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This smoke-free hotel includes 2 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, express check-out, and free airport shuttle. There's a bar/lounge on site, and concierge services and free newspapers are also provided.

DoubleTree by Hilton San Diego - Del Mar

11915 El Camino Real, San Diego, CA

Free Cancellation

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This hotel features an outdoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 9 conference rooms, free WiFi in public areas, and express check-out. Enjoy the gym and unwind at the bar/lounge and poolside bar.

Pool

Hot Tub

Embassy Suites by Hilton San Diego La Jolla

4550 La Jolla Village Dr, San Diego, CA

Free Cancellation

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This traditional hotel includes 2 restaurants, an indoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and WiFi in public areas. Enjoy the gym and free perks like on-the-go breakfast and a beach shuttle.

Lafayette Hotel & Club

2223 El Cajon Blvd, San Diego, CA

Free Cancellation

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This smoke-free hotel features 2 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. Enjoy the outdoor pool and conveniences like a 24-hour front desk and concierge services.

Palihotel San Diego Gaslamp Quarter

830 Sixth Avenue, San Diego, CA

Free Cancellation

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This hotel features a restaurant and 2 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and dry cleaning are also offered.

Sheraton San Diego Resort

1380 Harbor Island Dr, San Diego, CA

Free Cancellation

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A marina, 5 restaurants, and 3 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Enjoy the 2 hot tubs, and relax with drinks at the bar/lounge and poolside bar.

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Little Italy hotels essential information

Accommodation	8,090 hotels
Lowest Price
Highest Price
Popular hotels	Manchester Grand Hyatt San Diego, San Diego Marriott La Jolla, Marriott Marquis San Diego Marina, Embassy Suites by Hilton San Diego Bay Downtown, DoubleTree by Hilton Hotel San Diego - Mission Valley, Sheraton Mission Valley San Diego Hotel, Wyndham San Diego Bayside, DoubleTree by Hilton San Diego - Del Mar, Embassy Suites by Hilton San Diego La Jolla, Lafayette Hotel & Club, Palihotel San Diego Gaslamp Quarter, Sheraton San Diego Resort

Recent Little Italy hotel reviews by fellow wanderers

The Dana on Mission Bay

5 out of 5

Posted 1 day ago

Travelocity Verified Review

"We loved staying at the Dana! We have decided that the next time we’re in San Diego, we will stay again! It is a beautiful property. The restaurant is so good and so are the pools. Every day we had an excellent experience with the staff and the cleanliness of the rooms. We loved that they turned over the room every morning and we had a freshly made bed to sleep in every night. I couldn’t have asked for a better experience!"

A verified traveler stayed at The Dana on Mission Bay