Explore top 2026 4 Star Hotels in Little Italy

Name: Marriott Marquis San Diego Marina
Price range: $350 total

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Top Little Italy 4 Star hotels

Manchester Grand Hyatt San Diego

1 Market Pl San Diego CA

Fully refundableReserve now, pay when you stay

$246 nightly

$285 total

Sep 7 - Sep 8

Total with taxes and fees

This smoke-free hotel includes 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in ...

Wyndham San Diego Bayside

1355 N Harbor Drive San Diego CA

Fully refundableReserve now, pay when you stay

$182 nightly

$211 total

Sep 7 - Sep 8

Total with taxes and fees

This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center and free WiFi in public ...

8.4/10 Very Good! (6,306 reviews)

"Loved the bay view"

Reviewed on Sep 3, 2026

Hard Rock Hotel San Diego

207 5th Ave San Diego CA

Fully refundableReserve now, pay when you stay

$239 nightly

$277 total

Sep 7 - Sep 8

Total with taxes and fees

A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy the 24-hour gym and perks like free WiFi. There's a bar/lounge ...

9/10 Wonderful! (4,293 reviews)

"Great experience!"

Reviewed on Sep 3, 2026

Omni San Diego Hotel at the Ballpark

675 L St San Diego CA

Fully refundableReserve now, pay when you stay

$206 nightly

$239 total

Sep 7 - Sep 8

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

Paradise Point Resort & Spa

1404 Vacation Rd San Diego CA

Fully refundableReserve now, pay when you stay

$254 nightly

$292 total

Sep 7 - Sep 8

Total with taxes and fees

This smoke-free resort features a full-service spa, a marina, and 3 restaurants. Family-friendly amenities include mini golf and kid-friendly dining, along with ...

Sheraton San Diego Resort

1380 Harbor Island Dr San Diego CA

$196 nightly

$225 total

Sep 8 - Sep 9

Total with taxes and fees

A marina, 5 restaurants, and 3 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi ...

8.6/10 Excellent! (3,670 reviews)

"Clean rooms nice activities and good food !"

Reviewed on Sep 3, 2026

Town and Country San Diego

500 Hotel Circle North San Diego CA

Fully refundableReserve now, pay when you stay

$249 nightly

$286 total

Sep 6 - Sep 7

Total with taxes and fees

This hotel features 2 restaurants, 2 outdoor pools, and a hot tub. Bring the family and enjoy the children's pool, waterslide, and playground. Enjoy the gym ...

8.6/10 Excellent! (1,834 reviews)

"If you haven’t stayed here yet, you’re missing out. This property is amazing for families and helps alleviate some of the need to go to places to entertain kids. Excellent service and rooms, we’ll definitely be back!"

Reviewed on Sep 4, 2026

Lafayette Hotel & Club

2223 El Cajon Blvd San Diego CA

Fully refundableReserve now, pay when you stay

$249 nightly

$286 total

Sep 8 - Sep 9

Total with taxes and fees

This smoke-free hotel features 2 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...

San Diego Mission Bay Resort

1775 E Mission Bay Dr San Diego CA

Fully refundableReserve now, pay when you stay

$221 nightly

$254 total

Sep 7 - Sep 8

Total with taxes and fees

A full-service spa, 2 restaurants, and 5 outdoor tennis courts are all featured at this Mediterranean resort. There's fun for all ages with a children's pool ...

8.6/10 Excellent! (1,583 reviews)

"Wonderful place, lovely view, relaxing"

Reviewed on Sep 4, 2026

Marriott Marquis San Diego Marina

333 W Harbor Dr San Diego CA

$302 nightly

$350 total

Sep 11 - Sep 12

Total with taxes and fees

A marina, 5 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Bring the family and enjoy the children's pool and kid-friendly dining. ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Little Italy hotel reviews by fellow wanderers

The Dana on Mission Bay

5 out of 5

Posted 3 hours ago

Travelocity Verified Review

"Great stay with beautiful grounds. Amazing view from the room. Would recommend and will definitely stay there again!"

A verified traveler stayed at The Dana on Mission Bay

Courtyard by Marriott San Diego Downtown Little Italy

5 out of 5

Posted 2 days ago

Travelocity Verified Review

"The area surrounding this hotel was amazing. Saturday farmers market was really nice and the amount of places for eating and shopping within walking distance was great!! The only thing I would warn other about is the parking garage is made for compact cars and the cost was a little much but they have cheaper parking across the street that was much easier for us with a larger vehicle. All in all we had a beautiful trip and the stay was fantastic!!!!"

A verified traveler stayed at Courtyard by Marriott San Diego Downtown Little Italy