Explore top 2026 4 Star Hotels in Little Italy

Name: Marriott Marquis San Diego Marina
Price range: $366 total
Rating: 9.2

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Top Little Italy 4 Star hotels

Manchester Grand Hyatt San Diego

1 Market Pl San Diego CA

Fully refundableReserve now, pay when you stay

$276 nightly

$320 total

Sep 11 - Sep 12

Total with taxes and fees

This smoke-free hotel includes 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in ...

9/10 Wonderful! (2,834 reviews)

"When visiting San Diego, I’ve made a few mistakes selecting hotels until I found Manchester Grand Hyatt. This hotel is amazing and extremely welcoming to children and pets!"

Reviewed on Sep 10, 2026

Wyndham San Diego Bayside

1355 N Harbor Drive San Diego CA

Fully refundableReserve now, pay when you stay

$182 nightly

$211 total

Sep 20 - Sep 21

Total with taxes and fees

This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center and free WiFi in public ...

Hard Rock Hotel San Diego

207 5th Ave San Diego CA

Fully refundableReserve now, pay when you stay

$237 nightly

$274 total

Sep 13 - Sep 14

Total with taxes and fees

A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy the 24-hour gym and perks like free WiFi. There's a bar/lounge ...

Omni San Diego Hotel at the Ballpark

675 L St San Diego CA

Fully refundableReserve now, pay when you stay

$204 nightly

$236 total

Sep 13 - Sep 14

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

9.2/10 Wonderful! (2,390 reviews)

"Staff was amazing big thanks to DJ with our stuff"

Reviewed on Sep 9, 2026

Paradise Point Resort & Spa

1404 Vacation Rd San Diego CA

Fully refundableReserve now, pay when you stay

$254 nightly

$292 total

Oct 4 - Oct 5

Total with taxes and fees

This smoke-free resort features a full-service spa, a marina, and 3 restaurants. Family-friendly amenities include mini golf and kid-friendly dining, along with ...

Sheraton San Diego Resort

1380 Harbor Island Dr San Diego CA

Fully refundableReserve now, pay when you stay

$213 nightly

$245 total

Sep 27 - Sep 28

Total with taxes and fees

A marina, 5 restaurants, and 3 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi ...

Town and Country San Diego

500 Hotel Circle North San Diego CA

Fully refundableReserve now, pay when you stay

$279 nightly

$321 total

Sep 11 - Sep 12

Total with taxes and fees

This hotel features 2 restaurants, 2 outdoor pools, and a hot tub. Bring the family and enjoy the children's pool, waterslide, and playground. Enjoy the gym ...

Lafayette Hotel & Club

2223 El Cajon Blvd San Diego CA

Fully refundableReserve now, pay when you stay

$249 nightly

$286 total

Sep 14 - Sep 15

Total with taxes and fees

This smoke-free hotel features 2 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...

9.4/10 Exceptional! (1,975 reviews)

"Very memorable, loved the diner"

Reviewed on Sep 9, 2026

San Diego Mission Bay Resort

1775 E Mission Bay Dr San Diego CA

Fully refundableReserve now, pay when you stay

$279 nightly

$321 total

Oct 4 - Oct 5

Total with taxes and fees

A full-service spa, 2 restaurants, and 5 outdoor tennis courts are all featured at this Mediterranean resort. There's fun for all ages with a children's pool ...

8.6/10 Excellent! (1,592 reviews)

"Mission Bay resort was a great place to stay close to all the attractions. Very centrally located staff was always very friendly. Service was great"

Reviewed on Sep 10, 2026

Marriott Marquis San Diego Marina

333 W Harbor Dr San Diego CA

Fully refundableReserve now, pay when you stay

$316 nightly

$366 total

Sep 11 - Sep 12

Total with taxes and fees

A marina, 5 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Bring the family and enjoy the children's pool and kid-friendly dining. ...

9.2/10 Wonderful! (2,207 reviews)

"The location was excellent. The amenities were wonderful. Couple of the Bell staff were not friendly at all and the wait for the elevators at time (especially an hour before check out time) was extremely long."

Reviewed on Sep 10, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Little Italy hotel reviews by fellow wanderers

The Sofia Hotel

5 out of 5

Posted 2 hours ago

Travelocity Verified Review

"Great historic property. Definitely has character. We enjoyed our stay. Clean, quiet and fairly centrally located for San Diego."

A verified traveler stayed at The Sofia Hotel

Handlery Hotel

5 out of 5

Posted 6 hours ago

Travelocity Verified Review

"I’ve disliked quite a few hotels around this area of SD, but this was my first overwhelmingly positive experience at a hotel in SD!! Everything was perfect; the staff, the room, the amenities, and location were all amazing! I will definitely be coming back next time :)"

A verified traveler stayed at Handlery Hotel