Explore top 2026 4 Star Hotels in Little Italy

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Sep 18 - Sep 20
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Sep 25 - Sep 27

Top Little Italy 4 Star hotels

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
Fully refundableReserve now, pay when you stay
$286 nightly
The price is $332 total per night from Sep 27 to Sep 28
$332 total
Sep 27 - Sep 28
Total with taxes and fees
This smoke-free hotel includes 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in ...
9/10 Wonderful! (2,846 reviews)
"Great location and rooms in good shape. Check in was smooth. Only downside: Parking sucks. Tiny, tiny parking stalls. Valet parking first three floors and mostly empty, everyone else has to squeeze into a small stalls and suffer dings to both sides of their vehicle."

Reviewed on Sep 16, 2026

Opens in a new windowManchester Grand Hyatt San Diego
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
Fully refundableReserve now, pay when you stay
$182 nightly
The price is $211 total per night from Sep 20 to Sep 21
$211 total
Sep 20 - Sep 21
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center and free WiFi in public ...
8.4/10 Very Good! (6,306 reviews)
"This is our third stay here, it has aged a bit and in need of updated decor and beds ..our room had only double beds ..they took out the queens and when 2 people are in 1 bed there's little room to toss and turn-for the price, having the smaller beds was NOT worth it ...bathrooms need improvement ..."

Reviewed on Sep 17, 2026

Opens in a new windowWyndham San Diego Bayside
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
$237 nightly
The price is $274 total per night from Sep 27 to Sep 28
$274 total
Sep 27 - Sep 28
Total with taxes and fees
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy the 24-hour gym and perks like free WiFi. There's a bar/lounge ...
9/10 Wonderful! (4,379 reviews)
"The staff were super friendly and helpful. The room was clean and very nice. The only thing I was unaware of was the valet parking is the only parking they have. They will take it out of the incidental you pay though. Overall an amazing trip."

Reviewed on Sep 17, 2026

Opens in a new windowHard Rock Hotel San Diego
Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark

4 out of 5
675 L St San Diego CA
Fully refundableReserve now, pay when you stay
$222 nightly
The price is $258 total per night from Sep 27 to Sep 28
$258 total
Sep 27 - Sep 28
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Opens in a new windowOmni San Diego Hotel at the Ballpark
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
$261 nightly
The price is $300 total per night from Oct 4 to Oct 5
$300 total
Oct 4 - Oct 5
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 3 restaurants. Family-friendly amenities include mini golf and kid-friendly dining, along with ...
Opens in a new windowParadise Point Resort & Spa
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
$213 nightly
The price is $245 total per night from Sep 27 to Sep 28
$245 total
Sep 27 - Sep 28
Total with taxes and fees
A marina, 5 restaurants, and 3 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi ...
Opens in a new windowSheraton San Diego Resort
Town and Country San Diego

Town and Country San Diego

4 out of 5
500 Hotel Circle North San Diego CA
Fully refundableReserve now, pay when you stay
$242 nightly
The price is $278 total per night from Sep 18 to Sep 19
$278 total
Sep 18 - Sep 19
Total with taxes and fees
This hotel features 2 restaurants, 2 outdoor pools, and a hot tub. Bring the family and enjoy the children's pool, waterslide, and playground. Enjoy the gym ...
8.6/10 Excellent! (1,895 reviews)
"Nice"

Reviewed on Sep 16, 2026

Opens in a new windowTown and Country San Diego
Lafayette Hotel & Club

Lafayette Hotel & Club

4 out of 5
2223 El Cajon Blvd San Diego CA
Fully refundableReserve now, pay when you stay
$273 nightly
The price is $314 total per night from Sep 28 to Sep 29
$314 total
Sep 28 - Sep 29
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...
Opens in a new windowLafayette Hotel & Club
San Diego Mission Bay Resort

San Diego Mission Bay Resort

4 out of 5
1775 E Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
$286 nightly
The price is $329 total per night from Sep 20 to Sep 21
$329 total
Sep 20 - Sep 21
Total with taxes and fees
A full-service spa, 2 restaurants, and 5 outdoor tennis courts are all featured at this Mediterranean resort. There's fun for all ages with a children's pool ...
Opens in a new windowSan Diego Mission Bay Resort
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4 out of 5
333 W Harbor Dr San Diego CA
Fully refundableReserve now, pay when you stay
$312 nightly
The price is $361 total per night from Sep 30 to Oct 1
$361 total
Sep 30 - Oct 1
Total with taxes and fees
A marina, 5 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Bring the family and enjoy the children's pool and kid-friendly dining. ...
Opens in a new windowMarriott Marquis San Diego Marina
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Little Italy hotel reviews by fellow wanderers

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

5 out of 5
Posted 6 hours ago
Travelocity Verified Review
"The staff were super friendly and helpful. The room was clean and very nice. The only thing I was unaware of was the valet parking is the only parking they have. They will take it out of the incidental you pay though. Overall an amazing trip."
A verified traveler stayed at Hard Rock Hotel San Diego
Hard Rock Hotel San Diego

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