Explore top 2026 4 Star Hotels in Little Italy

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Top Little Italy 4 Star hotels

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
Fully refundableReserve now, pay when you stay
$286 nightly
The price is $332 total per night from Sep 27 to Sep 28
$332 total
Sep 27 - Sep 28
Total with taxes and fees
This smoke-free hotel includes 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in ...
9/10 Wonderful! (2,873 reviews)
"The pictures on this website are terrible. I was extremely hesitant, but because it was a Hyatt location. I decided to go with my gut because I’ve stayed at Hyatt before. When I arrived at the hotel did not disappoint. Everything was amazing. If you’re thinking to book a room at this hotel do it. ..."

Reviewed on Sep 22, 2026

Opens in a new windowManchester Grand Hyatt San Diego
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Sep 27 to Sep 28
$211 total
Sep 27 - Sep 28
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center and free WiFi in public ...
8.4/10 Very Good! (6,340 reviews)
"Amazing location but the property is in need of some maintenance. Since we stayed here a year ago there is no longer an airport shuttle, and there are areas that need some attention such as the beds, bathrooms and elevators. Just starting to feel a bit dated."

Reviewed on Sep 22, 2026

Opens in a new windowWyndham San Diego Bayside
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
$229 nightly
The price is $265 total per night from Sep 28 to Sep 29
$265 total
Sep 28 - Sep 29
Total with taxes and fees
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy the 24-hour gym and perks like free WiFi. There's a bar/lounge ...
Opens in a new windowHard Rock Hotel San Diego
Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark

4 out of 5
675 L St San Diego CA
$222 nightly
The price is $258 total per night from Sep 27 to Sep 28
$258 total
Sep 27 - Sep 28
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Opens in a new windowOmni San Diego Hotel at the Ballpark
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
$254 nightly
The price is $292 total per night from Oct 4 to Oct 5
$292 total
Oct 4 - Oct 5
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 3 restaurants. Family-friendly amenities include mini golf and kid-friendly dining, along with ...
Opens in a new windowParadise Point Resort & Spa
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
$213 nightly
The price is $245 total per night from Sep 27 to Sep 28
$245 total
Sep 27 - Sep 28
Total with taxes and fees
A marina, 5 restaurants, and 3 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi ...
Opens in a new windowSheraton San Diego Resort
Town and Country San Diego

Town and Country San Diego

4 out of 5
500 Hotel Circle North San Diego CA
Fully refundableReserve now, pay when you stay
$254 nightly
The price is $292 total per night from Sep 28 to Sep 29
$292 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel features 2 restaurants, 2 outdoor pools, and a hot tub. Bring the family and enjoy the children's pool, waterslide, and playground. Enjoy the gym ...
Opens in a new windowTown and Country San Diego
Lafayette Hotel & Club

Lafayette Hotel & Club

4 out of 5
2223 El Cajon Blvd San Diego CA
Fully refundableReserve now, pay when you stay
$273 nightly
The price is $314 total per night from Sep 28 to Sep 29
$314 total
Sep 28 - Sep 29
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...
9.4/10 Exceptional! (2,013 reviews)
"Property was amazing, however the pool was always very crowded and you have to reserve sun beds in advance, they were all taken the 3 days we were there. Otherwise everything was great"

Reviewed on Sep 22, 2026

Opens in a new windowLafayette Hotel & Club
San Diego Mission Bay Resort

San Diego Mission Bay Resort

4 out of 5
1775 E Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
$271 nightly
The price is $312 total per night from Sep 23 to Sep 24
$312 total
Sep 23 - Sep 24
Total with taxes and fees
A full-service spa, 2 restaurants, and 5 outdoor tennis courts are all featured at this Mediterranean resort. There's fun for all ages with a children's pool ...
Opens in a new windowSan Diego Mission Bay Resort
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4 out of 5
333 W Harbor Dr San Diego CA
$312 nightly
The price is $361 total per night from Sep 30 to Oct 1
$361 total
Sep 30 - Oct 1
Total with taxes and fees
A marina, 5 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Bring the family and enjoy the children's pool and kid-friendly dining. ...
9.2/10 Wonderful! (2,225 reviews)
"This was an A+ property. Beautifully maintained and efficient staff. We loved lounging by the pool and how close the hotel is to everything."

Reviewed on Sep 22, 2026

Opens in a new windowMarriott Marquis San Diego Marina
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Recent Little Italy hotel reviews by fellow wanderers

Hilton Garden Inn San Diego Downtown/Bayside

Hilton Garden Inn San Diego Downtown/Bayside

5 out of 5
Posted less than an hour ago
Travelocity Verified Review
"Super Clean!"
A verified traveler stayed at Hilton Garden Inn San Diego Downtown/Bayside
Hilton Garden Inn San Diego Downtown/Bayside

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