Book a hotel near Florida Keys National Marine Sanctuary, Key West
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Top hotels close to Florida Keys National Marine Sanctuary

Old Town 2 Bicycles, Grill, WiFi, 1st Floor, Pool! Rent 30 days get 20% discount
0.23 mi from Florida Keys National Marine Sanctuary
A water park and an outdoor pool are featured at this smoke-free condo. A garden, laundry facilities, and barbecue grills are also on offer.
Pool
Kitchen

BOOKING SMOKING HOT 2025 DEALS NOW!
0.27 mi from Florida Keys National Marine Sanctuary
This condo includes a garden and laundry facilities.
Pool
Kitchen

Caribbean House
226 Petronia St, Key West, FL
0.29 mi from Florida Keys National Marine Sanctuary
This bed & breakfast features free WiFi in public areas, concierge services, and self parking. Enjoy the free local cuisine breakfast each morning. A terrace, express check-in, and express check-out are also on offer.
Breakfast included
Free WiFi

Weatherstation Inn
57 Front St, Key West, FL
Free Cancellation
Reserve now, pay when you stay
0.36 mi from Florida Keys National Marine Sanctuary
An outdoor pool, free self parking, and concierge services are featured at this bed & breakfast. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A terrace and free newspapers are also provided.
Pool
Breakfast included

Lighthouse Hotel - Key West Historic Inns
902 Whitehead St, Key West, FL
Free Cancellation
Reserve now, pay when you stay
0.4 mi from Florida Keys National Marine Sanctuary
This hotel features an outdoor pool and a poolside bar. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A terrace, a garden, and a picnic area are also on offer.
Pool
Breakfast included

The Cabana Inn Key West - Adults Only
413 Applerouth Lane, Key West, FL
Free Cancellation
Reserve now, pay when you stay
0.42 mi from Florida Keys National Marine Sanctuary
This guesthouse features an outdoor pool and a hot tub. Enjoy the free continental breakfast each morning. Self parking, a terrace, and a garden are also offered.
Pool
Hot Tub

Duval House
815 Duval St, Key West, FL
0.48 mi from Florida Keys National Marine Sanctuary
This bed & breakfast features a terrace, concierge services, and self parking. A garden, a picnic area, and express check-in are also on offer.
Air conditioning
Parking available

La Concha Key West, Autograph Collection
430 Duval St, Key West, FL
Free Cancellation
Reserve now, pay when you stay
0.5 mi from Florida Keys National Marine Sanctuary
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, and valet parking. There's a poolside bar on site, and a 24-hour front desk and concierge services are also provided.
Pool
Pet friendly

Orchid Key Inn - Adults Only
1004 Duval St, Key West, FL
0.52 mi from Florida Keys National Marine Sanctuary
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Enjoy the hot tub and free perks like continental breakfast and WiFi in public areas. Self parking, a garden, and dry cleaning are also offered.
Pool
Hot Tub

Southernmost Beach Resort and Guesthouses
1319 Duval Street, Key West, FL
Free Cancellation
0.7 mi from Florida Keys National Marine Sanctuary
This hotel features a full-service spa, 3 outdoor pools, and a restaurant. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Traveling for business? Take advantage of the 24-hour business center, laundry service, and conference space.
Pool
Spa

The Southernmost Inn - Adults Only
525 United Street, Key West, FL
Free Cancellation
Reserve now, pay when you stay
0.7 mi from Florida Keys National Marine Sanctuary
This hotel's 2 outdoor pools and hot tub are among the featured amenities. Enjoy the free continental breakfast each morning. Self parking, a coffee shop, and a terrace are also offered.
Pool
Hot Tub

Hyatt Centric Key West Resort and Spa
601 Front St, Key West, FL
Free Cancellation
Reserve now, pay when you stay
0.8 mi from Florida Keys National Marine Sanctuary
This eco-certified resort features a full-service spa, a marina, and a restaurant. Enjoy the outdoor pool and perks like free WiFi. Enjoy the 24-hour gym and unwind at the bar/lounge and poolside bar.
Pool
Spa
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See all available properties in Florida Keys National Marine Sanctuary
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Florida Keys National Marine Sanctuary hotels essential information
Accommodation | 2,722 hotels |
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Lowest Price | |
Highest Price | |
Popular hotels | Southernmost Beach Resort and Guesthouses, Duval House, La Concha Key West, Autograph Collection, Hyatt Centric Key West Resort and Spa, Caribbean House, Old Town 2 Bicycles, Grill, WiFi, 1st Floor, Pool! Rent 30 days get 20% discount, Lighthouse Hotel - Key West Historic Inns, The Cabana Inn Key West - Adults Only, Orchid Key Inn - Adults Only, BOOKING SMOKING HOT 2025 DEALS NOW!, The Southernmost Inn - Adults Only, Weatherstation Inn |
Recent Florida Keys National Marine Sanctuary hotel reviews by fellow wanderers

Orchid Key Inn - Adults Only
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Great location... remodeled and they did an amazing job. Staff were amazing. On site bar and happy hour. I will be staying here again. "
A verified traveler stayed at Orchid Key Inn - Adults Only
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