Book a hotel near Florida Keys National Marine Sanctuary, Key West
Seize Your Someday with our amazing deals for the whole family!
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top hotels close to Florida Keys National Marine Sanctuary

The Cabana Inn Key West - Adults Only
413 Applerouth Lane Key West FL
0.42 mi from Florida Keys National Marine Sanctuary
$203 nightly
The price is $229 total per night
$229 total
May 10 - May 11
Total with taxes and fees
This guesthouse features an outdoor pool and a hot tub. Enjoy the free continental breakfast each morning. Self parking, a terrace, and a garden are also offered.
Pool
Hot Tub

Duval House
815 Duval St Key West FL
0.49 mi from Florida Keys National Marine Sanctuary
$220 nightly
The price is $244 total per night
$244 total
Apr 28 - Apr 29
Total with taxes and fees
This bed & breakfast features a terrace, concierge services, and self parking. A garden, a picnic area, and express check-in are also on offer.
Air conditioning
Parking available

La Concha Key West, Autograph Collection
430 Duval St Key West FL
Free Cancellation
Reserve now, pay when you stay
0.5 mi from Florida Keys National Marine Sanctuary
$310 nightly
The price is $349 total per night
$349 total
May 10 - May 11
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, and valet parking. There's a poolside bar on site, and a 24-hour front desk and concierge services are also provided.
Pool
Pet friendly

Douglas House - Adults Only
419 Amelia St Key West FL
0.56 mi from Florida Keys National Marine Sanctuary
$217 nightly
The price is $244 total per night
$244 total
May 4 - May 5
Total with taxes and fees
An outdoor pool is featured at this guesthouse, along with free WiFi in public areas and a terrace. A garden, a picnic area, and luggage storage are also on offer.
Pool
Free WiFi

Heron House - Adult Only
512 Simonton St Key West FL
0.56 mi from Florida Keys National Marine Sanctuary
$174 nightly
The price is $196 total per night
$196 total
Apr 28 - Apr 29
Total with taxes and fees
This bed & breakfast features an outdoor pool and a rooftop terrace. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A garden, luggage storage, and concierge services are also on offer.
Pool
Breakfast included

Opal Key Resort & Marina, Key West
245 Front Street Key West FL
Free Cancellation
Reserve now, pay when you stay
0.57 mi from Florida Keys National Marine Sanctuary
$304 nightly
The price is $342 total per night
$342 total
May 3 - May 4
Total with taxes and fees
A marina, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the outdoor pool and visit the 3 bars/lounges and poolside bar for drinks.
Pool
Hot Tub

The Southernmost Inn - Adults Only
525 United Street Key West FL
Free Cancellation
Reserve now, pay when you stay
0.7 mi from Florida Keys National Marine Sanctuary
$264 nightly
The price is $297 total per night
$297 total
May 10 - May 11
Total with taxes and fees
This hotel's 2 outdoor pools and hot tub are among the featured amenities. Enjoy the free continental breakfast each morning. Self parking, a coffee shop, and a terrace are also offered.
Pool
Hot Tub

Southernmost Beach Resort and Guesthouses
1319 Duval Street Key West FL
Free Cancellation
Reserve now, pay when you stay
0.71 mi from Florida Keys National Marine Sanctuary
$330 nightly
The price is $372 total per night
$372 total
May 19 - May 20
Total with taxes and fees
This hotel features a full-service spa, 3 outdoor pools, and a restaurant. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Traveling on business? Take advantage of the 2 conference rooms, along with dry cleaning/laundry services.
Pool
Spa

Pier House Resort & Spa
1 Duval St Key West FL
Free Cancellation
Reserve now, pay when you stay
0.73 mi from Florida Keys National Marine Sanctuary
$595 nightly
The price is $669 total per night
$669 total
May 10 - May 11
Total with taxes and fees
This smoke-free resort features a private beach, a full-service spa, and a restaurant. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Traveling on business? Take advantage of the 2 conference rooms, business center, and express check-in.
On private beach
Pool

NYAH Key West - Adults Only
420 Margaret Street Key West FL
Free Cancellation
Reserve now, pay when you stay
0.84 mi from Florida Keys National Marine Sanctuary
$178 nightly
The price is $201 total per night
$201 total
May 10 - May 11
Total with taxes and fees
This guesthouse's 3 outdoor pools and a rooftop terrace are among the featured amenities. Enjoy the hot tub and free continental breakfast each morning. There's a bar/lounge on site, and a 24-hour front desk and concierge services are also provided.
Pool
Hot Tub

The Reach Key West, Curio Collection by Hilton
1435 Simonton Street Key West FL
Free Cancellation
Reserve now, pay when you stay
0.85 mi from Florida Keys National Marine Sanctuary
$330 nightly
The price is $371 total per night
$371 total
May 4 - May 5
Total with taxes and fees
This resort features a private beach, a full-service spa, and a restaurant. Traveling on business? Take advantage of the express check-out, laundry service, and valet parking. Enjoy the outdoor pool and unwind at the bar/lounge and poolside bar.
On private beach
Pool

Casa Marina Key West, Curio Collection by Hilton
1500 Reynolds Street Key West FL
Free Cancellation
Reserve now, pay when you stay
1.09 mi from Florida Keys National Marine Sanctuary
$377 nightly
The price is $424 total per night
$424 total
May 3 - May 4
Total with taxes and fees
A private beach, a full-service spa, and 2 outdoor pools are all featured at this smoke-free resort. Relax with sun loungers and beach umbrellas, and cool off with a drink at the beachside bar. Enjoy the gym and perks like free WiFi.
On private beach
Pool
Don't see what you're looking for?
See all available properties in Florida Keys National Marine Sanctuary
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Florida Keys National Marine Sanctuary hotels essential information
Accommodation | 2,666 hotels |
|---|---|
Lowest Price | $196 |
Highest Price | $669 |
Popular hotels | Southernmost Beach Resort and Guesthouses, La Concha Key West, Autograph Collection, Pier House Resort & Spa, Opal Key Resort & Marina, Key West, Casa Marina Key West, Curio Collection by Hilton, The Cabana Inn Key West - Adults Only, The Southernmost Inn - Adults Only, NYAH Key West - Adults Only, Duval House, Heron House - Adult Only, Douglas House - Adults Only, The Reach Key West, Curio Collection by Hilton |
Recent Florida Keys National Marine Sanctuary hotel reviews by fellow wanderers

Duval House
5 out of 5
Posted 5 hours ago
Travelocity Verified Review
"Is a great location "
A verified traveler stayed at Duval House
More ways to wander Florida Keys National Marine Sanctuary
Explore More Ways to Travel with Travelocity
- Historic Seaport Hotels
- Hotels near Jackson Square
- Hotels near Tennessee Williams Key West Exhibit
- Key West Historic District Hotels
- 4 Star Hotels in Key West
- 5 Star Hotels in Key West
- Apartments in Key West
- B&B in Key West
- Cabins in Key West
- Condos in Key West
- Cottages in Key West
- Extended Stay Hotels in Key West
- Guest Houses in Key West
- Hostels in Key West
- All Inclusive Resorts & in Key West
- Beach Resorts & in Key West
- Boutique Hotels in Key West
- Casino Resorts & in Key West
- Cheap Hotels in Key West
- Convention Center Hotels in Key West
- Kid Friendly Hotels in Key West
- Gay Friendly Hotels in Key West
- Golf Resorts & in Key West
- Hilton Hotels in Key West
- Historic Hotels in Key West
- Hotels with Suites in Key West
- Hotels with Pools in Key West
- Hotels with a Lazy River in Key West
- Hotels with Free Breakfast in Key West
- Hotels with Free Airport Shuttle in Key West
- Hotels with Free Parking in Key West
- Hotels with Hot Tubs in Key West
- Hotels with Kitchenettes in Key West
- Hotels with Waterslides in Key West
- Hyatt Hotels in Key West
- Luxury Hotels in Key West
- Pet Friendly Hotels in Key West
- Romantic Getaways & Hotels in Key West
- Spa Resorts & in Key West
- Waterpark Hotels and Resorts in Key West
- Key West Hotels
- Houseboats in Key West
- Vacation Homes in Key West
- Resorts in Key West
- Villas in Key West
- Hotels near Florida Keys Eco - Discovery Center
- Hotels near Key West Museum of Art and History
- Hotels near Harry S. Truman Little White House
- Hotels near Key West Shipwreck Museum
- Hotels near The Kite House
- Hotels near Ernest Hemingway Home and Museum
- Hotels near Museum of Art & History at the Custom House
- Hotels near Oldest House Museum and Garden
- Uptown - Upper Duval Hotels
- Hotels near Duval Street
- Hotels near Mallory Dock
- Adults Only Resorts & in Bahama Village
- Spa Resorts & in Bahama Village
- Bahama Village Hotels
- Hotels near San Carlos Institute - Casa Cuba
- Hotels near Audubon House and Tropical Gardens
- Beach Resorts & in Truman Annex
- Hotels with Pools in Truman Annex
- Pet Friendly Hotels in Truman Annex
- Truman Annex Hotels
- Hotels near Fort Zachary Taylor Historic State Park
- Hotels near Key West Lighthouse and Keeper's Quarters Museum
- Hotels near Red Barn Theater
- Hotels near St. Paul's Episcopal Church
- Hotels near Key West Butterfly and Nature Conservatory
- Hotels near South Beach
- Hotels near Mallory Square
- Hotels near Southernmost Point
- Hotels near Mel Fisher Maritime Museum
- Old Town Key West Hotels
- Car rental Key West
- Convertible Car Rentals in Key West
- Economy Car Rentals in Key West
- Luxury Car Rentals in Key West
- Mini Car Rentals in Key West
- Minivan Car Rentals in Key West
- Pickup Car Rentals in Key West
- Suv Car Rentals in Key West
- Van Car Rentals in Key West
- Car rentals near Harry S. Truman Little White House
- Car rentals near Duval Street
- Houseboats in Key West
- Hotels near Mallory Square
- Family Hotels in Key West
- Key West vacation rentals
- Visit Duval Street
- Hotels in Key West Historic District
- Hotels near Duval Street
- Car rentals in Key West
- Condos in Key West
- Visit Fort Zachary Taylor Historic State Park
- Flights to Key West
- Romantic Hotels in Key West
- Key West vacations
- Pet-friendly Hotels in Key West
- Hotels in Key West
- Cheap Hotels in Key West
- Beach Hotels in Key West
- Oceanfront Hotels in Key West
- All-inclusive Resorts in Key West





