Book a hotel near Florida Keys National Marine Sanctuary, Key West
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Top hotels close to Florida Keys National Marine Sanctuary

Walkable Cottage w/ Pool Access in Key West!
Key West FL
0.22 mi from Florida Keys National Marine Sanctuary
This cottage doesn't skimp on freebies - guests receive free WiFi and free self parking. An outdoor pool is also provided.
Pool
Kitchen

Caribbean House
226 Petronia St Key West FL
0.29 mi from Florida Keys National Marine Sanctuary
$208 nightly
The price is $231 total per night
$231 total
Nov 1 - Nov 2
Total with taxes and fees
This bed & breakfast features free WiFi in public areas, concierge services, and self parking. Enjoy the free local cuisine breakfast each morning. A terrace, express check-in, and express check-out are also on offer.
Breakfast included
Free WiFi

Tranquility Guest House
302 Angela st Key West FL
0.3 mi from Florida Keys National Marine Sanctuary
$188 nightly
The price is $211 total per night
$211 total
Nov 1 - Nov 2
Total with taxes and fees
An outdoor pool is featured at this hotel, along with free WiFi in public areas and a garden. Express check-out, luggage storage, and a virtual front desk are also on offer.
Pool
Free WiFi

Duval House
815 Duval St Key West FL
0.49 mi from Florida Keys National Marine Sanctuary
$181 nightly
The price is $200 total per night
$200 total
Nov 1 - Nov 2
Total with taxes and fees
This bed & breakfast features a terrace, concierge services, and self parking. A garden, a picnic area, and express check-in are also on offer.
Air conditioning
Parking available

Wicker Guesthouse
913 Duval Street Key West FL
0.5 mi from Florida Keys National Marine Sanctuary
$219 nightly
The price is $246 total per night
$246 total
Nov 1 - Nov 2
Total with taxes and fees
This guesthouse features an outdoor pool and a bar/lounge. Guests will appreciate free perks like free self parking and WiFi in public areas. A terrace, a garden, and a library are also on offer.
Pool
Breakfast included

La Concha Key West, Autograph Collection
430 Duval St Key West FL
Free Cancellation
Reserve now, pay when you stay
0.5 mi from Florida Keys National Marine Sanctuary
$293 nightly
The price is $330 total per night
$330 total
Nov 23 - Nov 24
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, and valet parking. There's a poolside bar on site, and a 24-hour front desk and concierge services are also provided.
Pool
Pet friendly

Douglas House - Adults Only
419 Amelia St Key West FL
0.56 mi from Florida Keys National Marine Sanctuary
$199 nightly
The price is $224 total per night
$224 total
Nov 2 - Nov 3
Total with taxes and fees
An outdoor pool is featured at this guesthouse, along with free WiFi in public areas and a terrace. A garden, a picnic area, and luggage storage are also on offer.
Pool
Free WiFi

Opal Key Resort & Marina, Key West
245 Front Street Key West FL
Free Cancellation
Reserve now, pay when you stay
0.57 mi from Florida Keys National Marine Sanctuary
$294 nightly
The price is $331 total per night
$331 total
Nov 29 - Nov 30
Total with taxes and fees
A marina, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Enjoy the outdoor pool and visit the 3 bars/lounges and poolside bar for drinks.
Pool
Hot Tub

The Southernmost Inn - Adults Only
525 United Street Key West FL
Free Cancellation
Reserve now, pay when you stay
0.7 mi from Florida Keys National Marine Sanctuary
$169 nightly
The price is $190 total per night
$190 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel's 2 outdoor pools and hot tub are among the featured amenities. Enjoy the free continental breakfast each morning. Self parking, a coffee shop, and a terrace are also offered.
Pool
Hot Tub

Southernmost Beach Resort and Guesthouses
1319 Duval Street Key West FL
Free Cancellation
Reserve now, pay when you stay
0.71 mi from Florida Keys National Marine Sanctuary
$263 nightly
The price is $296 total per night
$296 total
Nov 15 - Nov 16
Total with taxes and fees
A full-service spa, 3 outdoor pools, and a restaurant are all featured at this hotel. Traveling on business? Take advantage of the 2 conference rooms, free WiFi in public areas, and laundry service. 2 poolside bars and 2 bars/lounges are featured at this hotel, along with a gym.
Pool
Spa

Pier House Resort & Spa
1 Duval St Key West FL
Free Cancellation
Reserve now, pay when you stay
0.73 mi from Florida Keys National Marine Sanctuary
$376 nightly
The price is $423 total per night
$423 total
Nov 1 - Nov 2
Total with taxes and fees
This smoke-free resort features a private beach, a full-service spa, and a restaurant. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Traveling on business? Take advantage of the 2 conference rooms, business center, and express check-in.
On private beach
Pool

Winslow's Bungalows - Key West Historic Inns
725 Truman Avenue Key West FL
Free Cancellation
Reserve now, pay when you stay
0.73 mi from Florida Keys National Marine Sanctuary
$275 nightly
The price is $309 total per night
$309 total
Nov 1 - Nov 2
Total with taxes and fees
This smoke-free hotel features 3 outdoor pools, a bar/lounge, and a poolside bar. WiFi in public areas is free. Self parking, a garden, and luggage storage are also offered.
Pool
Pet friendly
Don't see what you're looking for?
See all available properties in Florida Keys National Marine Sanctuary
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Florida Keys National Marine Sanctuary hotels essential information
Accommodation | 2,616 hotels |
|---|---|
Lowest Price | $190 |
Highest Price | $423 |
Popular hotels | Southernmost Beach Resort and Guesthouses, Opal Key Resort & Marina, Key West, The Southernmost Inn - Adults Only, La Concha Key West, Autograph Collection, Duval House, Tranquility Guest House , Winslow's Bungalows - Key West Historic Inns, Douglas House - Adults Only, Pier House Resort & Spa, Caribbean House, Wicker Guesthouse, Walkable Cottage w/ Pool Access in Key West! |
Recent Florida Keys National Marine Sanctuary hotel reviews by fellow wanderers

La Concha Key West, Autograph Collection
4 out of 5
Posted 3 hours ago
Travelocity Verified Review
"Extra star for our room location. We were given room on 3rd floor overlooking Duval St. The only thing better would be the 2nd floor with the balcony. Negatives: AC didn’t get very cold. The fridge is more like a cooler (staff’s words). So luckily we brought a cooler. No ice machine to get your own ice (but staff will give you gallon Ziploc bags of ice upon request). Our room had large water stain on fridge cabinet. On first morning we had no cups to make coffee in room and the glasses were dirty (remedied by room service). Our room had no microwave. It did have Keurig but no plugin nearby its storage location. Being an older hotel, the king room we had is smaller so space was understandably limited. No drawers to unpack suitcase and with limited space it was cramped with suitcase open. Just note this in case you want more space. Positives: hotel gave us a $50 daily credit for drinks on site (charge drinks to room and credit is on bill)."
A verified traveler stayed at La Concha Key West, Autograph Collection
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