Explore top 2026 5 Star Hotels in Otay Mesa
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Top Otay Mesa 5 Star hotels

Pendry San Diego
550 J Street San Diego CA
Fully refundableReserve now, pay when you stay
$342 nightly
The price is $397 total per night from May 21 to May 22
$397 total
May 21 - May 22
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.2/10 Wonderful! (1,003 reviews)
Room was dirty and a few bugs on the bed
Reviewed on Apr 25, 2026

The US Grant, a Luxury Collection Hotel, San Diego
326 Broadway San Diego CA
Fully refundableReserve now, pay when you stay
$247 nightly
The price is $287 total per night from May 25 to May 26
$287 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, express check-out, and ...
9/10 Wonderful! (1,003 reviews)
This hotel met all our needs. Very clean room, comfortable bed, quiet location, excellent robes and great location!
Reviewed on Apr 11, 2026

Shore House at The Del, LXR Hotels & Resorts
1500 Orange Avenue Coronado CA
$708 nightly
The price is $786 total per night from May 3 to May 4
$786 total
May 3 - May 4
Total with taxes and fees
A private beach, 7 restaurants, and 2 outdoor pools are all featured at this luxury resort. Relax with beach cabanas and sun loungers, and cool off with a drink ...
9.2/10 Wonderful! (139 reviews)
The rooms, facilities, location and amenities are all wonderful. Great property for families. The 4 stars is due to the lack of staff at times. The breakfast buffet was delicious however, during peak hours there were many tables that were not cleaned timely which left us waiting before we could sit. ...
Reviewed on Apr 11, 2026

The Bower Coronado
1417 Orange Ave Coronado CA
Fully refundableReserve now, pay when you stay
$349 nightly
The price is $385 total per night from Apr 27 to Apr 28
$385 total
Apr 27 - Apr 28
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
9.2/10 Wonderful! (215 reviews)
Perfect boutique hotel ! Across the street from the Hotel Del Coronado and from the beach , super close to restaurants plus has a really cute rooftop bar/ restaurant! The hotel is very clean , staff is very helpful and kind , room is a bit small but everything is top notch… blow dryer ? Dyson of ...
Reviewed on Apr 23, 2026

Beach Village at The Del, LXR Hotels & Resorts
1500 Orange Avenue Coronado CA
$925 nightly
The price is $1,017 total per night from May 10 to May 11
$1,017 total
May 10 - May 11
Total with taxes and fees
A private beach, 7 restaurants, and 3 outdoor pools are all featured at this smoke-free resort. Enjoy beachfront dining and relax with beach cabanas and sun ...
9.2/10 Wonderful! (133 reviews)
We got treated very bad
Reviewed on Apr 7, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Otay Mesa hotel reviews by fellow wanderers

Bay Club Hotel & Marina
4 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Great view of the marina
Room was nice though the hotel felt dated"
A verified traveler stayed at Bay Club Hotel & Marina
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