Book Hotels in South San Diego, CA

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Top South San Diego hotels

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
Fully refundableReserve now, pay when you stay
$244 nightly
The price is $283 total per night from Jul 28 to Jul 29
$283 total
Jul 28 - Jul 29
Total includes taxes and fees
This eco-certified hotel includes 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi ...
"Enjoyed my stay at this place. Friendly and courteous staff"

Reviewed on Jul 21, 2025

Manchester Grand Hyatt San Diego
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4 out of 5
333 W Harbor Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
$272 nightly
The price is $315 total per night from Jul 28 to Jul 29
$315 total
Jul 28 - Jul 29
Total includes taxes and fees
This smoke-free hotel features a full-service spa, a marina, and 5 restaurants. Families will appreciate the children's pool and onsite laundry facilities. Enjoy ...
"I had a great experience at this hotel! Everything was spotlessly clean, and the service was excellent!friendly, helpful staff made me feel welcome from the moment I arrived. The location is also a big plus—within easy walking distance to lots of entertainment, restaurants, and attractions. I would ..."

Reviewed on Jul 22, 2025

Marriott Marquis San Diego Marina
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $206 total per night from Aug 10 to Aug 11
$206 total
Aug 10 - Aug 11
Total includes taxes and fees
A marina, 2 outdoor pools, and 2 hot tubs are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi ...
"Nice"

Reviewed on Jul 23, 2025

The Dana on Mission Bay
Hilton San Diego Bayfront

Hilton San Diego Bayfront

4 out of 5
1 Park Blvd, San Diego, CA
$244 nightly
The price is $282 total per night from Aug 14 to Aug 15
$282 total
Aug 14 - Aug 15
Total includes taxes and fees
A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Bring the family and enjoy the children's pool and kid-friendly dining. ...
"we enjoyed the hotels location, the hotels clean and the staff was very professional"

Reviewed on Jul 21, 2025

Hilton San Diego Bayfront
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive, San Diego, CA
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $195 total per night from Jul 27 to Jul 28
$195 total
Jul 27 - Jul 28
Total includes taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, express check-out, and ...
"Great location and the staff were all friendly and helpful. Definitely needs some attention to the room though. Drapes were torn and tattered. But I would stay again."

Reviewed on Jul 23, 2025

Wyndham San Diego Bayside
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
$111 nightly
The price is $128 total per night from Aug 24 to Aug 25
$128 total
Aug 24 - Aug 25
Total includes taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
"The best part of this place was the fabulous pool. The staff was helpful and pleasant. The room was adequate, but it could use a facelift. Wall paper was warped towards the floor and our sliding door was stuck. Air conditioning worked very well, and the beds were comfortable. I will stay here again. ..."

Reviewed on Jul 23, 2025

Handlery Hotel
Gaylord Pacific Resort & Convention Center

Gaylord Pacific Resort & Convention Center

4 out of 5
1000 H Street, Chula Vista, CA
Fully refundableReserve now, pay when you stay
$350 nightly
The price is $407 total per night from Aug 13 to Aug 14
$407 total
Aug 13 - Aug 14
Total includes taxes and fees
A full-service spa, 8 restaurants, and 3 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
"Great property with fantastic staff!"

Reviewed on Jul 24, 2025

Gaylord Pacific Resort & Convention Center
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2.5 out of 5
2296 Niels Bohr Ct, San Diego, CA
Fully refundable
$139 nightly
The price is $158 total per night from Aug 10 to Aug 11
$158 total
Aug 10 - Aug 11
Total includes taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"This hotel is in an industrial area, pretty remote. Our room had no towels and TVremote was not working. AC worked great."

Reviewed on Jul 24, 2025

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
The Dextro Hotel, BW Premier Collection

The Dextro Hotel, BW Premier Collection

3 out of 5
1617 1st Avenue, San Diego, CA
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $157 total per night from Jul 30 to Jul 31
$157 total
Jul 30 - Jul 31
Total includes taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Staff was very accommodating and acknowledged our separate requests. The pool is small but accessible until 11 PM. The gym is tucked away in a very discreet area, by the pool, which I appreciated. The property bar also had a happy hour, and the bar staff was just as nice and accommodating as the ..."

Reviewed on Jul 23, 2025

The Dextro Hotel, BW Premier Collection
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap South San Diego hotels

The Rambler Motel

The Rambler Motel

225 Bay Blvd, Chula Vista, CA
$118 nightly
The price is $136 total per night from Aug 3 to Aug 4
$136 total
Aug 3 - Aug 4
Total includes taxes and fees
9/10 Wonderful! (1,878 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent South San Diego hotel reviews by fellow wanderers

Gaylord Pacific Resort & Convention Center

Gaylord Pacific Resort & Convention Center

5 out of 5
Posted 10 hours ago
Travelocity Verified Review
"Great property with fantastic staff!"
A verified traveler stayed at Gaylord Pacific Resort & Convention Center
Gaylord Pacific Resort & Convention Center
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