Book Hotels in Pamplico, SC
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check hotel availability in Pamplico
Top Pamplico hotels

Howard Johnson by Wyndham Florence
2038 W Lucas Street, I-95 Exit 164, Florence, SC
Free Cancellation
Reserve now, pay when you stay
20.97 mi from city center
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business center. A garden and a computer station are also provided.
Breakfast included
Parking included

Park Inn by Radisson Florence, SC
1729 Mandeville Road, Florence, SC
Free Cancellation
Reserve now, pay when you stay
20.92 mi from city center
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. Enjoy the 24-hour gym and conveniences like a 24-hour front desk and laundry facilities.
Breakfast included
Pet friendly

Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr, Florence, SC
Free Cancellation
Reserve now, pay when you stay
20.5 mi from city center
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like on-the-go breakfast and free self parking.
Pool
Breakfast included

Comfort Inn & Suites
527 Woody Jones Blvd, Florence, SC
Free Cancellation
Reserve now, pay when you stay
20.07 mi from city center
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the free continental breakfast each morning.
Pool
Breakfast included

Days Inn by Wyndham Florence/I-95 North
2111 West Lucas St/I-95, I-95 & Hwy 52 Exit 164, Florence, SC
Free Cancellation
Reserve now, pay when you stay
21.21 mi from city center
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this motel. Guests will appreciate free perks like on-the-go breakfast and WiFi in public areas. A garden and a safe deposit box are also provided.
Pool
Breakfast included

TownePlace Suites by Marriott Florence
2650 Hospitality Boulevard, Florence, SC
Free Cancellation
Reserve now, pay when you stay
19.98 mi from city center
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included

Hyatt Place Florence Downtown
100 East Evans Street Florence, Florence, SC
Free Cancellation
Reserve now, pay when you stay
17.65 mi from city center
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the 24-hour gym and free continental breakfast each morning.
Pool
Breakfast included

La Quinta Inn & Suites by Wyndham Florence
2123 W Lucas St, Florence, SC
Free Cancellation
Reserve now, pay when you stay
21.08 mi from city center
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.
Pool
Breakfast included

Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr, Florence, SC
Free Cancellation
Reserve now, pay when you stay
20.46 mi from city center
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business center. Enjoy the seasonal outdoor pool and conveniences like a 24-hour front desk and laundry facilities.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Pamplico with star-rating
HTG-Star-Rating-Links-ModuleTitle-Subheadline

4 Star Hotels
1 properties

3 Star Hotels
12 properties
Pamplico hotels essential information
Accommodation | 134 hotels |
---|---|
Lowest Price | |
Highest Price | |
Popular hotels | Howard Johnson by Wyndham Florence, Park Inn by Radisson Florence, SC, Quality Inn & Suites Florence Civic Center, Comfort Inn & Suites, Days Inn by Wyndham Florence/I-95 North, TownePlace Suites by Marriott Florence, Hyatt Place Florence Downtown, La Quinta Inn & Suites by Wyndham Florence, Days Inn by Wyndham Florence Near Civic Center |
Frequently asked questions
Recent Pamplico hotel reviews by fellow wanderers

Comfort Inn & Suites
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"This was our second visit to this hotel for an overnight. Still very clean surroundings outside and inside. Friendly staff greeted us even when we checked in later in the evening. Very nice setup for water station. The breakfast area was very nicely setup for breakfast. The food selection was great for complimentary offer. It was a very nice stay and comfortable. We'd stay again. "
A verified traveler stayed at Comfort Inn & Suites
Types of hotels
Hotels near…
Hotels by star rating
Areas of Pamplico
Most popular
Hotels
Cheap Hotels in ColumbiaCheap Hotels in Pawleys IslandCheap Hotels in Myrtle BeachMyrtle Beach Pet Friendly HotelsMyrtle Beach Beach Resorts & HotelsCheap Hotels in SummervilleCheap Hotels in CharlestonMyrtle Beach All Inclusive Resorts & HotelsNorth Myrtle Beach Beach Resorts & HotelsCheap Hotels in Surfside BeachCheap Hotels in Murrells InletHilton Head Island Beach Resorts & HotelsCheap Hotels in ConwayCheap Hotels in GreenvilleCheap Hotels in Hilton Head IslandCheap Hotels in North Myrtle BeachCheap Hotels in North CharlestonCharleston Beach Resorts & HotelsCheap Hotels in Rock Hill
Cars
Activities