Book Hotels in Sellers, SC
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Top Sellers hotels

Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
Fully refundable
$85 nightly
The price is $95 total per night from May 17 to May 18
$95 total
May 17 - May 18
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. Enjoy ...
This is a pretty good hotel, clean and quiet. The breakfast was fine. I have stayed here before and will return.
Reviewed on Apr 20, 2026

Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
Fully refundable
$100 nightly
The price is $112 total per night from May 17 to May 18
$112 total
May 17 - May 18
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
Every thing excellent only breakfast below the par. No fruits no yogurt just simple breakfast.
Reviewed on Apr 21, 2026

Hyatt Place Florence Downtown
100 East Evans Street Florence Florence SC
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $137 total per night from May 4 to May 5
$137 total
May 4 - May 5
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Staff was very friendly and helpful. Hotel was in a great location. Enjoyed our stay. Would definitely stay there again.
Reviewed on Apr 20, 2026

Howard Johnson by Wyndham Florence
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $75 total per night from Apr 26 to Apr 27
$75 total
Apr 26 - Apr 27
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Surprisingly nice. I was impressed with the all brick building. They went out of their way to get a milk for my diabetic sister for our travel even after the breakfast service was closed.
Reviewed on Apr 22, 2026

Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $108 total per night from Apr 28 to Apr 29
$108 total
Apr 28 - Apr 29
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Small breakfast but the bed was awesome and room was clean
Reviewed on Apr 21, 2026

Spark by Hilton Florence North I-95, SC
1739 Mandeville Rd Florence SC
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $104 total per night from May 3 to May 4
$104 total
May 3 - May 4
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Clean rooms. Helpful staff good location. It will be better if they offer better options in breakfast.
Reviewed on Apr 18, 2026

Days Inn by Wyndham Florence/I-95 North
2111 West Lucas St/I-95 Florence SC
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $69 total per night from Apr 23 to Apr 24
$69 total
Apr 23 - Apr 24
Total with taxes and fees
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this motel. Guests will appreciate free perks like on-the-go breakfast and ...
Our room was clean. The check in was quick and breakfast was as expected.
Reviewed on Apr 20, 2026

Charming Cottage with easy access to local attractions-pet and kid friendly
Sellers SC
$180 nightly
The price is $196 total per night from Apr 23 to Apr 24
$196 total
Apr 23 - Apr 24
Total with taxes and fees
This cottage featured laundry facilities and barbecue grills.

Stunning historic home w/ large rooms. Close to attractions. Kid & pet friendly!
Sellers SC
$594 nightly
The price is $647 total per night from Apr 24 to Apr 25
$647 total
Apr 24 - Apr 25
Total with taxes and fees
This farm stay features a garden, laundry facilities, and barbecue grills.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Sellers hotel reviews by fellow wanderers

Howard Johnson by Wyndham Florence
4 out of 5
Posted 8 hours ago
Travelocity Verified Review
"Surprisingly nice. I was impressed with the all brick building. They went out of their way to get a milk for my diabetic sister for our travel even after the breakfast service was closed."
A verified traveler stayed at Howard Johnson by Wyndham Florence
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