Explore top 2026 4 Star Hotels in Texas Medical Center

Name: The Whitehall Houston
Price range: $140 total
Rating: 8.6

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Top Texas Medical Center 4 Star hotels

Hotel Zaza Houston Museum District

5701 Main Street Houston TX

Fully refundableReserve now, pay when you stay

$214 nightly

$250 total

Sep 4 - Sep 5

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...

9.2/10 Wonderful! (1,001 reviews)

"My stay was exceptional well! Will return."

Reviewed on Sep 3, 2026

Club Quarters Hotel Downtown, Houston

1085 Rusk Street Houston TX

Fully refundableReserve now, pay when you stay

$85 nightly

$99 total

Sep 7 - Sep 8

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

Hilton Houston Plaza/Medical Center

6633 Travis St Houston TX

Fully refundableReserve now, pay when you stay

$79 nightly

$92 total

Sep 6 - Sep 7

Total with taxes and fees

This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free ...

8.4/10 Very Good! (2,132 reviews)

"Food could be better."

Reviewed on Sep 3, 2026

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

5353 Westheimer Rd Houston TX

Fully refundableReserve now, pay when you stay

$115 nightly

$134 total

Sep 11 - Sep 12

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like a free area shuttle. Valet parking, a business center, ...

The Royal Sonesta Houston Galleria

2222 West Loop South Houston TX

Fully refundableReserve now, pay when you stay

$119 nightly

$139 total

Sep 7 - Sep 8

Total with taxes and fees

This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, express check-out, ...

8.8/10 Excellent! (2,225 reviews)

"Nice"

Reviewed on Sep 3, 2026

Blossom Hotel Houston, Curio Collection by Hilton

7118 Bertner Ave Houston TX

Fully refundableReserve now, pay when you stay

$140 nightly

$164 total

Sep 6 - Sep 7

Total with taxes and fees

A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

The Moran CITYCENTRE

800 Sorella Court Houston TX

Fully refundableReserve now, pay when you stay

$188 nightly

$220 total

Sep 4 - Sep 5

Total with taxes and fees

This smoke-free hotel includes 2 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

Marriott Marquis Houston

1777 Walker Street Houston TX

Fully refundableReserve now, pay when you stay

$245 nightly

$286 total

Sep 17 - Sep 18

Total with taxes and fees

A full-service spa, 5 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...

DoubleTree by Hilton Hotel Houston - Greenway Plaza

Houston TX

Fully refundableReserve now, pay when you stay

$77 nightly

$90 total

Sep 10 - Sep 11

Total with taxes and fees

This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express ...

8.4/10 Very Good! (1,848 reviews)

"The downstairs escalator from the garage is broken so you have to walk up the escalator like stairs. The parking in the garage is expensive and a little complicated. Overall, very nice location and staff. The room was clean enough besides the occasional random hairs."

Reviewed on Sep 3, 2026

The Whitehall Houston

1700 Smith St Houston TX

Fully refundableReserve now, pay when you stay

$120 nightly

$140 total

Sep 17 - Sep 18

Total with taxes and fees

This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8.6/10 Excellent! (2,387 reviews)

"We had a wonderful stay at The Whitehall hotel for my sister’s birthday! Special thanks to Ana Maria, the house supervisor, for welcoming us warmly. The check-in process was smooth and efficient because of her! For breakfast, we were expecting a breakfast buffet but were surprised at the a la carte ..."

Reviewed on Sep 3, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.