Explore top 2026 4 Star Hotels in Texas Medical Center

Name: Doubletree by Hilton Houston Hobby Airport
Price range: $115 total
Rating: 8.8

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Top Texas Medical Center 4 Star hotels

Hilton Houston Plaza/Medical Center

6633 Travis St Houston TX

Fully refundableReserve now, pay when you stay

$91 nightly

$107 total

Aug 16 - Aug 17

Total with taxes and fees

This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free ...

Club Quarters Hotel Downtown, Houston

1085 Rusk Street Houston TX

Fully refundableReserve now, pay when you stay

$94 nightly

$110 total

Jul 22 - Jul 23

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

Thompson Houston, by Hyatt

1717 ALLEN PARKWAY Houston TX

Fully refundableReserve now, pay when you stay

$249 nightly

$291 total

Aug 2 - Aug 3

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this Art Deco hotel. Enjoy the outdoor pool and perks like free WiFi and a free area ...

Grand Tuscany Hotel

12801 Northwest Fwy Houston TX

Fully refundableReserve now, pay when you stay

$96 nightly

$112 total

Jul 26 - Jul 27

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Families will appreciate the lazy river and picnic area. Enjoy the seasonal outdoor pool and perks ...

8/10 Very Good! (178 reviews)

"Front desk clerk never told me half of the hotel was under construction and that our room was in an entirely different building. Thinking it was in the main hotel my family and I waited for an elevator (in front of the front desk staff) and proceeded to the floor we thought our room was, got off ..."

Reviewed on Jul 18, 2026

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

5353 Westheimer Rd Houston TX

Fully refundableReserve now, pay when you stay

$115 nightly

$134 total

Jul 31 - Aug 1

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like a free area shuttle. Valet parking, a business center, ...

Blossom Hotel Houston, Curio Collection by Hilton

7118 Bertner Ave Houston TX

Fully refundableReserve now, pay when you stay

$147 nightly

$172 total

Jul 26 - Jul 27

Total with taxes and fees

A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

Hotel Zaza Houston Museum District

5701 Main Street Houston TX

Fully refundableReserve now, pay when you stay

$228 nightly

$267 total

Jul 25 - Jul 26

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...

9.2/10 Wonderful! (1,007 reviews)

"👍"

Reviewed on Jul 18, 2026

The Moran CITYCENTRE

800 Sorella Court Houston TX

Fully refundableReserve now, pay when you stay

$204 nightly

$239 total

Jul 26 - Jul 27

Total with taxes and fees

This smoke-free hotel includes 2 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

9/10 Wonderful! (1,114 reviews)

"Beautiful hotel - difficult to find my way around. The signage from the garage to the hotel is terrible. Signage near all elevators is terrible. I did a lot of unnecessary walking around hauling all my luggage which is a poor way to start a hotel stay. Maid service not great, but the rooms and public ..."

Reviewed on Jul 18, 2026

Marriott Marquis Houston

1777 Walker Street Houston TX

Fully refundableReserve now, pay when you stay

$241 nightly

$282 total

Aug 6 - Aug 7

Total with taxes and fees

A full-service spa, 4 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...

9/10 Wonderful! (1,164 reviews)

"I always enjoy our stay there. Kei always takes care of us poolside. I wish the rooms where more updated Our toilet would get stuck not a big deal but could really use an update to the rooms."

Reviewed on Jul 19, 2026

Doubletree by Hilton Houston Hobby Airport

Houston TX

Fully refundableReserve now, pay when you stay

$99 nightly

$115 total

Jul 26 - Jul 27

Total with taxes and fees

This hotel features 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the 24-hour business center, express check-in, and free ...

8.8/10 Excellent! (1,008 reviews)

"Was a good time"

Reviewed on Jul 19, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.