Explore the best 2025 4 Star Hotels Hotels in Texas Medical Center

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Top Texas Medical Center 4 Star hotels

Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street, Houston, TX
Free Cancellation
Reserve now, pay when you stay
$117 nightly
The price is $137 total per night
$137 total
Jun 4 - Jun 5
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Express check-in, express check-out, and a computer station are also on offer.
Pet friendly
Free WiFi
Magnolia Hotel Houston, A Tribute Portfolio Hotel

Magnolia Hotel Houston, A Tribute Portfolio Hotel

4 out of 5
1100 Texas St, Houston, TX
Free Cancellation
Reserve now, pay when you stay
$127 nightly
The price is $148 total per night
$148 total
Jun 5 - Jun 6
Total includes taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Enjoy the 24-hour gym and perks like a free area shuttle.
Pool
Pet friendly
DoubleTree by Hilton Hotel Houston - Greenway Plaza

DoubleTree by Hilton Hotel Houston - Greenway Plaza

4 out of 5
Free Cancellation
Reserve now, pay when you stay
$84 nightly
The price is $99 total per night
$99 total
Jun 8 - Jun 9
Total includes taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, and valet parking. Unwind with a drink at the bar/lounge and enjoy perks like a free area shuttle.
Pool
Free WiFi
Hilton Americas-Houston

Hilton Americas-Houston

4 out of 5
1600 Lamar Street, Houston, TX
Free Cancellation
Reserve now, pay when you stay
$145 nightly
The price is $170 total per night
$170 total
Jun 17 - Jun 18
Total includes taxes and fees
A full-service spa, 2 restaurants, and an indoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the express check-out, laundry service, and valet parking. Make the most of the 24-hour gym and a rooftop terrace, and relax with drinks at one of the 2 bars/lounges.
Pool
Hot Tub
The Whitehall Houston

The Whitehall Houston

4 out of 5
1700 Smith St, Houston, TX
Free Cancellation
Reserve now, pay when you stay
$127 nightly
The price is $149 total per night
$149 total
Jun 8 - Jun 9
Total includes taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Unwind with a drink at the bar/lounge and enjoy perks like a free area shuttle.
Pool
Pet friendly
Houston Marriott Westchase

Houston Marriott Westchase

4 out of 5
2900 Briarpark Dr, Houston, TX
Free Cancellation
Reserve now, pay when you stay
$104 nightly
The price is $121 total per night
$121 total
May 31 - Jun 1
Total includes taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the indoor pool and perks like free self parking.
Pool
Hot Tub
C. Baldwin, Curio Collection by Hilton

C. Baldwin, Curio Collection by Hilton

4 out of 5
400 Dallas St, Houston, TX
Free Cancellation
Reserve now, pay when you stay
$169 nightly
The price is $198 total per night
$198 total
Jun 15 - Jun 16
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. A free area shuttle is offered as well. Valet parking, a 24-hour business center, and a coffee shop are also offered.
Pet friendly
Restaurant
Hyatt Regency Houston/Galleria

Hyatt Regency Houston/Galleria

4 out of 5
2626 Sage Road, Houston, TX
Free Cancellation
Reserve now, pay when you stay
$136 nightly
The price is $159 total per night
$159 total
Jun 5 - Jun 6
Total includes taxes and fees
This hotel features 2 bars/lounges, a poolside bar, and a restaurant. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, and valet parking. There's an outdoor pool on site, and a 24-hour front desk and a coffee shop are also provided.
Pool
Free WiFi
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd, Houston, TX
Free Cancellation
Reserve now, pay when you stay
$120 nightly
The price is $140 total per night
$140 total
Jun 8 - Jun 9
Total includes taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like a free area shuttle. Valet parking, a business center, and a terrace are also offered.
Pool
Pet friendly
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street, Houston, TX
Free Cancellation
Reserve now, pay when you stay
$242 nightly
The price is $283 total per night
$283 total
Jun 8 - Jun 9
Total includes taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury aparthotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Enjoy the outdoor pool and perks like a free area shuttle.
Pool
Pet friendly
Omni Houston Hotel

Omni Houston Hotel

4 out of 5
4 Riverway, Houston, TX
Free Cancellation
Reserve now, pay when you stay
$193 nightly
The price is $226 total per night
$226 total
Jun 3 - Jun 4
Total includes taxes and fees
A full-service spa, a nightclub, and 2 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Unwind with a drink at one of the 3 bars/lounges and enjoy perks like a free area shuttle.
Pool
Spa
The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria

4 out of 5
2222 West Loop South, Houston, TX
Free Cancellation
Reserve now, pay when you stay
$170 nightly
The price is $199 total per night
$199 total
Jun 6 - Jun 7
Total includes taxes and fees
This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, express check-out, and valet parking. A bar/lounge, a 24-hour front desk, and a coffee shop are also provided.
Pool
Pet friendly
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Texas Medical Center hotels essential information

Accommodation
6,254 hotels
Lowest Price
$99
Highest Price
$283
Popular hotels
Club Quarters Hotel Downtown, Houston, Magnolia Hotel Houston, A Tribute Portfolio Hotel, DoubleTree by Hilton Hotel Houston - Greenway Plaza, Hilton Americas-Houston, The Whitehall Houston, Houston Marriott Westchase, C. Baldwin, Curio Collection by Hilton, Hyatt Regency Houston/Galleria, DoubleTree by Hilton Hotel & Suites Houston by the Galleria, Hotel Zaza Houston Museum District, Omni Houston Hotel, The Royal Sonesta Houston Galleria

Recent Texas Medical Center hotel reviews by fellow wanderers

Magnolia Hotel Houston, A Tribute Portfolio Hotel

Magnolia Hotel Houston, A Tribute Portfolio Hotel

5 out of 5
Posted 12 hours ago
Travelocity Verified Review
"I really enjoyed my stay here. The property is very nice and has a nice atmosphere. I love the interior decor. The room was very clean and I absolutely loved the large garden tub in the room. I did not get a chance to check out the rooftop pool and hot tub. I will definitely do that my next trip. there's a lot of close by dining options in downtown nightlife within walking distance. My only criticism is that I feel the valet parking thing was a little overpriced and the parking nearby was difficult to find at times. mainly because the closest garage is used by the valet so the spots were very sparing. otherwise, I love this hotel and would definitely return. "
A verified traveler stayed at Magnolia Hotel Houston, A Tribute Portfolio Hotel
Magnolia Hotel Houston, A Tribute Portfolio Hotel

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