Explore top 2026 4 Star Hotels in Texas Medical Center

Name: Doubletree by Hilton Houston Hobby Airport
Price range: $114 total
Rating: 8.8

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Top Texas Medical Center 4 Star hotels

Hilton Houston Plaza/Medical Center

6633 Travis St Houston TX

Fully refundableReserve now, pay when you stay

$107 total

per night

Aug 16 - Aug 17

This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free ...

Club Quarters Hotel Downtown, Houston

1085 Rusk Street Houston TX

Fully refundableReserve now, pay when you stay

$110 total

per night

Jul 22 - Jul 23

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8.6/10 Excellent! (4,339 reviews)

"Beautiful rooms. Great walking distance to the many establishments around Houston."

Reviewed on Jul 17, 2026

Thompson Houston, by Hyatt

1717 ALLEN PARKWAY Houston TX

Fully refundableReserve now, pay when you stay

$291 total

per night

Aug 2 - Aug 3

A full-service spa, a 24-hour gym, and a restaurant are all featured at this Art Deco hotel. Enjoy the outdoor pool and perks like free WiFi and a free area ...

Grand Tuscany Hotel

12801 Northwest Fwy Houston TX

Fully refundableReserve now, pay when you stay

$113 total

per night

Jul 26 - Jul 27

This hotel features a restaurant, a gym, and a bar/lounge. Families will appreciate the lazy river and picnic area. Enjoy the seasonal outdoor pool and perks ...

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

5353 Westheimer Rd Houston TX

Fully refundableReserve now, pay when you stay

$134 total

per night

Jul 31 - Aug 1

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like a free area shuttle. Valet parking, a business center, ...

Blossom Hotel Houston, Curio Collection by Hilton

7118 Bertner Ave Houston TX

Fully refundableReserve now, pay when you stay

$154 total

per night

Aug 16 - Aug 17

A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

Hotel Zaza Houston Museum District

5701 Main Street Houston TX

A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...

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The Moran CITYCENTRE

800 Sorella Court Houston TX

Fully refundableReserve now, pay when you stay

$220 total

per night

Jul 19 - Jul 20

This smoke-free hotel includes 2 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

9/10 Wonderful! (1,112 reviews)

"They charged me twice for the room after I had already paid with Expedia."

Reviewed on Jul 17, 2026

Marriott Marquis Houston

1777 Walker Street Houston TX

Fully refundableReserve now, pay when you stay

$272 total

per night

Jul 30 - Jul 31

A full-service spa, 4 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...

Doubletree by Hilton Houston Hobby Airport

Houston TX

Fully refundableReserve now, pay when you stay

$114 total

per night

Jul 23 - Jul 24

This hotel features 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the 24-hour business center, express check-in, and free ...

8.8/10 Excellent! (1,003 reviews)

"Great staff, great decoration during World Cup. Place was quiet clean and most of all loved the gym!"

Reviewed on Jul 17, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.