Explore top 2026 4 Star Hotels in Texas Medical Center

Name: C. Baldwin, Curio Collection by Hilton
Price range: $215 total
Rating: 8.4

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Top Texas Medical Center 4 Star hotels

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

5353 Westheimer Rd Houston TX

Fully refundableReserve now, pay when you stay

$119 nightly

$139 total

Jan 23 - Jan 24

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like a free area shuttle. Valet parking, a business center, ...

8.2/10 Very Good! (3,266 reviews)

Great location

Reviewed on Jan 14, 2026

The Royal Sonesta Houston Galleria

2222 West Loop South Houston TX

$159 nightly

$186 total

Jan 23 - Jan 24

Total with taxes and fees

This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, express check-out, ...

8.4/10 Very Good! (1,549 reviews)

Great stay

Reviewed on Jan 13, 2026

The Westin Galleria Houston

5060 W Alabama St Houston TX

$215 nightly

$252 total

Jan 30 - Jan 31

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

9/10 Wonderful! (1,005 reviews)

Spotless rooms, great housekeeping, nice smell throughtout the hotel, top notch fitness facilities. Courteous front desk staff

Reviewed on Jan 4, 2026

Club Quarters Hotel Downtown, Houston

1085 Rusk Street Houston TX

$96 nightly

$112 total

Jan 22 - Jan 23

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8.4/10 Very Good! (4,026 reviews)

The staff was friendly and accommodating. The furniture in the room was a little hit or miss. Stayed in a room with a sofa, the first room did not have a sofa, the second room had a slightly leaky sink. The staff moved me no problem. The sheets were wonderful and the coffee machine was great. Love ...

Reviewed on Jan 16, 2026

Blossom Hotel Houston, Curio Collection by Hilton

7118 Bertner Ave Houston TX

Fully refundableReserve now, pay when you stay

$139 nightly

$162 total

Feb 15 - Feb 16

Total with taxes and fees

A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

9/10 Wonderful! (3,647 reviews)

I loved everything

Reviewed on Jan 11, 2026

Hotel Zaza Houston Museum District

5701 Main Street Houston TX

Fully refundableReserve now, pay when you stay

$283 nightly

$331 total

Jan 19 - Jan 20

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury aparthotel. Traveling on business? Take advantage of the 24-hour business ...

8.8/10 Excellent! (1,880 reviews)

Extremely helpful staff, excellent service. Location is convenient to everything.

Reviewed on Jan 12, 2026

Magnolia Hotel Houston, A Tribute Portfolio Hotel

1100 Texas St Houston TX

$146 nightly

$170 total

Jan 18 - Jan 19

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

9/10 Wonderful! (1,409 reviews)

Greatness …

Reviewed on Jan 15, 2026

Omni Houston Hotel

4 Riverway Houston TX

Fully refundableReserve now, pay when you stay

$178 nightly

$208 total

Jan 23 - Jan 24

Total with taxes and fees

A full-service spa, a nightclub, and 2 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

9/10 Wonderful! (1,007 reviews)

Very courteous and efficient

Reviewed on Jan 10, 2026

DoubleTree by Hilton Hotel Houston - Greenway Plaza

Houston TX

Fully refundableReserve now, pay when you stay

$103 nightly

$120 total

Jan 29 - Jan 30

Total with taxes and fees

This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express ...

8.2/10 Very Good! (1,428 reviews)

Clean room, nice location, good amenities, attentive staff. A bit old.

Reviewed on Jan 9, 2026

C. Baldwin, Curio Collection by Hilton

400 Dallas St Houston TX

Fully refundableReserve now, pay when you stay

$183 nightly

$215 total

Feb 6 - Feb 7

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. A free area shuttle is offered as well. Valet parking, a 24-hour business center, and a coffee ...

8.4/10 Very Good! (1,001 reviews)

Everything was perfect

Reviewed on Jan 12, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Texas Medical Center hotel reviews by fellow wanderers

Club Quarters Hotel Downtown, Houston

5 out of 5

Posted 17 hours ago

Travelocity Verified Review

"The staff was friendly and accommodating. The furniture in the room was a little hit or miss. Stayed in a room with a sofa, the first room did not have a sofa, the second room had a slightly leaky sink. The staff moved me no problem. The sheets were wonderful and the coffee machine was great. Love the fact that they had a workout facility. The mattress was a little saggy, but the shower was hot and the restrooms were clean. I would stay again."

A verified traveler stayed at Club Quarters Hotel Downtown, Houston