Explore top 2025 5 Star Hotels in Missouri City

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Top Missouri City 5 Star hotels

The Post Oak Hotel at Uptown Houston

1600 West Loop South, Houston, TX

$474 nightly

$555 total

Nov 23 - Nov 24

Total with taxes and fees

A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

9.6/10 Exceptional! (854 reviews)

Loved it. That's it. Nothing else to say.

Reviewed on Nov 2, 2025

Four Seasons Hotel Houston

1300 Lamar St, Houston, TX

Fully refundableReserve now, pay when you stay

$584 nightly

$684 total

Nov 21 - Nov 22

Total with taxes and fees

A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...

9/10 Wonderful! (1,001 reviews)

Jacob at the front desk was awesome!

Reviewed on Aug 31, 2025

JW Marriott Houston Downtown

806 Main Street, Houston, TX

Fully refundableReserve now, pay when you stay

$190 nightly

$221 total

Nov 28 - Nov 29

Total with taxes and fees

A full-service spa, a gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, express check-in, ...

9/10 Wonderful! (1,014 reviews)

Room was clean and properly set up. staff was very friendly and professional

Reviewed on Nov 5, 2025

ACP Hotel Houston Westchase, MOD Collection by Sonesta

6855 W Sam Houston Pkwy S, Houston, TX

Fully refundableReserve now, pay when you stay

$75 nightly

$88 total

Nov 11 - Nov 12

Total with taxes and fees

This aparthotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...

7.8/10 Good! (1,004 reviews)

The room was decent. They could have given atleast 2 water bottles per room. I had to buy for 2$/ bottle at the reception. But they allowed mid night check-in and parking was nice.

Reviewed on Nov 3, 2025

The St. Regis Houston

1919 Briar Oaks Ln, Houston, TX

Fully refundableReserve now, pay when you stay

$412 nightly

$482 total

Nov 23 - Nov 24

Total with taxes and fees

A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Families will appreciate the onsite laundry facilities and babysitting. ...

9/10 Wonderful! (399 reviews)

Fantastic staff and service

Reviewed on Oct 15, 2025

La Colombe d'Or Hotel

3410 Montrose Blvd, Houston, TX

Fully refundableReserve now, pay when you stay

$433 nightly

$506 total

Nov 10 - Nov 11

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

9.2/10 Wonderful! (135 reviews)

Very comfy stay overall. In the tower the whole building made random squeaking noises which were annoying but over all very nice hotel.

Reviewed on Oct 11, 2025

7550 Kirby Dr

7550 Kirby Dr, 911, Houston, TX

This apartment doesn't skimp on freebies - guests receive free WiFi and free self parking. An outdoor pool and laundry facilities are also provided.

8.2/10 Very Good! (45 reviews)

I enjoyed my stay it was worth it

Reviewed on Aug 3, 2025

Get rates

TUSCAN VILLA

3130 S Rice Ave, Houston, TX

This villa doesn't skimp on freebies - guests receive free WiFi and free self parking. Valet parking, dry cleaning, and luggage storage are also offered.

Would not recommend . We booked on the same day as check in, no one would answer the phone or let you into the property without 72 hours notice. We purchased the Villa for one night due to a flight cancellation, tried phoning multiple times and messaging before check in closed but no one would answer ...

Reviewed on Jul 14, 2024

Get rates

Don't see what you're looking for?

See all available properties in Missouri City

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Missouri City Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Missouri City to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Missouri City 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Missouri City before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.