Explore top 2025 4 Star Hotels in Texas Medical Center
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Top Texas Medical Center 4 Star hotels

Hotel Zaza Houston Museum District
5701 Main Street, Houston, TX
Fully refundableReserve now, pay when you stay
$226 nightly
The price is $265 total per night from Sep 21 to Sep 22
$265 total
Sep 21 - Sep 22
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury aparthotel. Traveling on business? Take advantage of the 24-hour business ...

Club Quarters Hotel Downtown, Houston
1085 Rusk Street, Houston, TX
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $133 total per night from Sep 10 to Sep 11
$133 total
Sep 10 - Sep 11
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
5353 Westheimer Rd, Houston, TX
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $137 total per night from Sep 14 to Sep 15
$137 total
Sep 14 - Sep 15
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like a free area shuttle. Valet parking, a business center, ...

Hyatt Regency Houston/Galleria
2626 Sage Road, Houston, TX
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $168 total per night from Oct 5 to Oct 6
$168 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features 2 bars/lounges, a poolside bar, and a restaurant. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...

DoubleTree by Hilton Hotel Houston - Greenway Plaza
Houston
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $117 total per night from Sep 18 to Sep 19
$117 total
Sep 18 - Sep 19
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express ...

The Westin Galleria Houston
5060 W Alabama St, Houston, TX
Fully refundableReserve now, pay when you stay
$252 nightly
The price is $295 total per night from Sep 19 to Sep 20
$295 total
Sep 19 - Sep 20
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

C. Baldwin, Curio Collection by Hilton
400 Dallas St, Houston, TX
Fully refundableReserve now, pay when you stay
$181 nightly
The price is $212 total per night from Sep 21 to Sep 22
$212 total
Sep 21 - Sep 22
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. A free area shuttle is offered as well. Valet parking, a 24-hour business center, and a coffee ...

The Whitehall Houston
1700 Smith St, Houston, TX
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $157 total per night from Sep 18 to Sep 19
$157 total
Sep 18 - Sep 19
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

Hilton Houston Plaza/Medical Center
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $127 total per night from Sep 14 to Sep 15
$127 total
Sep 14 - Sep 15
Total with taxes and fees
This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...

The Chifley Houston, Tapestry Collection by Hilton
2400 West Loop S, Houston, TX
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $153 total per night from Sep 12 to Sep 13
$153 total
Sep 12 - Sep 13
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...
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