Explore top 2026 4 Star Hotels in Texas Medical Center

Name: The Whitehall Houston
Price range: $143 total
Rating: 8.6

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Top Texas Medical Center 4 Star hotels

Hotel Zaza Houston Museum District

5701 Main Street Houston TX

Fully refundableReserve now, pay when you stay

$258 nightly

$301 total

Sep 10 - Sep 11

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...

Club Quarters Hotel Downtown, Houston

1085 Rusk Street Houston TX

$89 nightly

$104 total

Sep 11 - Sep 12

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8.6/10 Excellent! (4,486 reviews)

"It's a self check in. On the 8th floor we counted at least 3 different types of carpets from the elevator to our room. There were 3 separate lights that stretched across the top of the 2 beds but only 1 of the lights worked. When we 1st got in the room it was cold so we turned off the AC. Later we ..."

Reviewed on Sep 8, 2026

Hilton Houston Plaza/Medical Center

6633 Travis St Houston TX

Fully refundableReserve now, pay when you stay

$114 nightly

$134 total

Sep 24 - Sep 25

Total with taxes and fees

This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free ...

8.4/10 Very Good! (2,145 reviews)

"My room was missing a bathroom door.. also the table lamp chargers were not working… called reception and they replaced them"

Reviewed on Sep 8, 2026

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

5353 Westheimer Rd Houston TX

Fully refundableReserve now, pay when you stay

$123 nightly

$144 total

Sep 20 - Sep 21

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like a free area shuttle. Valet parking, a business center, ...

The Royal Sonesta Houston Galleria

2222 West Loop South Houston TX

$119 nightly

$139 total

Sep 12 - Sep 13

Total with taxes and fees

This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, express check-out, ...

8.8/10 Excellent! (2,244 reviews)

"Perfect experience, would 100% come back"

Reviewed on Sep 8, 2026

Blossom Hotel Houston, Curio Collection by Hilton

7118 Bertner Ave Houston TX

Fully refundableReserve now, pay when you stay

$148 nightly

$174 total

Sep 20 - Sep 21

Total with taxes and fees

A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

The Moran CITYCENTRE

800 Sorella Court Houston TX

Fully refundableReserve now, pay when you stay

$188 nightly

$220 total

Sep 12 - Sep 13

Total with taxes and fees

This smoke-free hotel includes 2 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

Marriott Marquis Houston

1777 Walker Street Houston TX

Fully refundableReserve now, pay when you stay

$313 nightly

$366 total

Sep 24 - Sep 25

Total with taxes and fees

A full-service spa, 5 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...

9/10 Wonderful! (1,291 reviews)

"Very nice property, great location."

Reviewed on Sep 8, 2026

DoubleTree by Hilton Hotel Houston - Greenway Plaza

Houston TX

Fully refundableReserve now, pay when you stay

$85 nightly

$100 total

Sep 20 - Sep 21

Total with taxes and fees

This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express ...

The Whitehall Houston

1700 Smith St Houston TX

Fully refundableReserve now, pay when you stay

$122 nightly

$143 total

Sep 28 - Sep 29

Total with taxes and fees

This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8.6/10 Excellent! (2,402 reviews)

"My experience at Whitehall was terrible , I can’t even sleep at night because I can hear the next room people are having sex and the noise of people walking on the front of my door ."

Reviewed on Sep 8, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Texas Medical Center hotel reviews by fellow wanderers

Hyatt Place Houston Medical Center

4 out of 5

Posted 2 hours ago

Travelocity Verified Review

"Everything OK good except one thing the parking they charge for the park I stay two different hotels, but I never charged for parking"

A verified traveler stayed at Hyatt Place Houston Medical Center

Hyatt House Houston Medical Center

5 out of 5

Posted 4 hours ago

Travelocity Verified Review

"The rooms were spacious, clean, included a full kitchen, comfy bed, and had exceptional city views, The manager, Precious Edwards, was very professional and quickly resolved issues. The pool and jacuzzi areas were awesome. The breakfast included with the rooms were delicious as well."

A verified traveler stayed at Hyatt House Houston Medical Center