Explore top 2025 5 Star Hotels in Midtown

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Top Midtown 5 Star hotels

The Post Oak Hotel at Uptown Houston

The Post Oak Hotel at Uptown Houston

5 out of 5
1600 West Loop South, Houston, TX
Fully refundableReserve now, pay when you stay
$479 nightly
The price is $561 total per night from Sep 30 to Oct 1
$561 total
Sep 30 - Oct 1
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
The Post Oak Hotel at Uptown Houston
Four Seasons Hotel Houston

Four Seasons Hotel Houston

5 out of 5
1300 Lamar St, Houston, TX
Fully refundableReserve now, pay when you stay
$524 nightly
The price is $613 total per night from Sep 11 to Sep 12
$613 total
Sep 11 - Sep 12
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...
Four Seasons Hotel Houston
JW Marriott Houston Downtown

JW Marriott Houston Downtown

5 out of 5
806 Main Street, Houston, TX
Fully refundableReserve now, pay when you stay
$214 nightly
The price is $249 total per night from Sep 5 to Sep 6
$249 total
Sep 5 - Sep 6
Total with taxes and fees
A full-service spa, a gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, express check-in, ...
JW Marriott Houston Downtown
ACP Hotel Houston Westchase, MOD Collection by Sonesta

ACP Hotel Houston Westchase, MOD Collection by Sonesta

5 out of 5
6855 W Sam Houston Pkwy S, Houston, TX
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $88 total per night from Sep 12 to Sep 13
$88 total
Sep 12 - Sep 13
Total with taxes and fees
This aparthotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
ACP Hotel Houston Westchase, MOD Collection by Sonesta
The St. Regis Houston

The St. Regis Houston

5 out of 5
1919 Briar Oaks Ln, Houston, TX
Fully refundableReserve now, pay when you stay
$458 nightly
The price is $535 total per night from Sep 5 to Sep 6
$535 total
Sep 5 - Sep 6
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Families will appreciate the onsite laundry facilities and babysitting. ...
The St. Regis Houston
La Colombe d'Or Hotel

La Colombe d'Or Hotel

5 out of 5
3410 Montrose Blvd, Houston, TX
Fully refundableReserve now, pay when you stay
$428 nightly
The price is $501 total per night from Sep 2 to Sep 3
$501 total
Sep 2 - Sep 3
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
La Colombe d'Or Hotel
7550 Kirby Dr

7550 Kirby Dr

5 out of 5
7550 Kirby Dr, 911, Houston, TX
This apartment doesn't skimp on freebies - guests receive free WiFi and free self parking. An outdoor pool and laundry facilities are also provided.
7550 Kirby Dr
TUSCAN VILLA

TUSCAN VILLA

5 out of 5
3130 S Rice Ave, Houston, TX
This villa doesn't skimp on freebies - guests receive free WiFi and free self parking. Valet parking, dry cleaning, and luggage storage are also offered.
TUSCAN VILLA
ECLIPZ Modern CEO Corp House

ECLIPZ Modern CEO Corp House

5 out of 5
4506 Champions Landing Dr, Houston, TX
$1,848 nightly
The price is $2,125 total per night from Sep 2 to Sep 3
$2,125 total
Sep 2 - Sep 3
Total with taxes and fees
This villa features free WiFi in public areas, laundry facilities, and valet parking. Dry cleaning and luggage storage are also provided.
ECLIPZ Modern CEO Corp House
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.