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Top hotels in Texas Medical Center

Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2 Houston TX
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $149 total per night from May 23 to May 24
$149 total
May 23 - May 24
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy the hot tub ...
The staff was very friendly and

Reviewed on May 15, 2026

Opens in a new windowHyatt Place Houston Medical Center
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
Fully refundable
$173 nightly
The price is $203 total per night from May 17 to May 18
$203 total
May 17 - May 18
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Check-in was quick and easy. The front desk was very friendly and accommodating. The shuttle service was very convenient for us because my husband had several appointments at MD Anderson so we used the shuttle service to get back and forth.

Reviewed on May 13, 2026

Opens in a new windowInterContinental Houston by IHG
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
Fully refundableReserve now, pay when you stay
$173 nightly
The price is $201 total per night from May 22 to May 23
$201 total
May 22 - May 23
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
We had a wonderful stay! Comfortable bed and great breakfast. Really nice staff. Walking distance to MD Anderson and healthy restaurants near by. Will be staying here for our MD Anderson visits.

Reviewed on May 10, 2026

Opens in a new windowThe Westin Houston Medical Center/Museum District
Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX

3 out of 5
6840 Almeda Rd Houston TX
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $125 total per night from May 23 to May 24
$125 total
May 23 - May 24
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Easy, clean, Hilton

Reviewed on May 16, 2026

Opens in a new windowHilton Garden Inn Houston Medical Center, TX
Hyatt House Houston Medical Center

Hyatt House Houston Medical Center

3 out of 5
7329 FANNIN STREET Houston TX
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $149 total per night from May 23 to May 24
$149 total
May 23 - May 24
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like buffet breakfast and WiFi in public areas. You'll ...
The bathroom needed a fan. .

Reviewed on May 16, 2026

Opens in a new windowHyatt House Houston Medical Center
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $188 total per night from May 24 to May 25
$188 total
May 24 - May 25
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
Very lovely hotel that we just discovered. It was like a luxury botique hotel where the staff treated guests like loving family. We loved all the details that really upgraded our stay. The food was wonderful as well. We particularily loved our waiter at breakfast, Oscar. We will definitely ...

Reviewed on May 16, 2026

Opens in a new windowBlossom Hotel Houston, Curio Collection by Hilton
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $99 total per night from May 24 to May 25
$99 total
May 24 - May 25
Total with taxes and fees
This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free ...
Breakfast was wonderful and the front desk staff were very helpful.

Reviewed on May 16, 2026

Opens in a new windowHilton Houston Plaza/Medical Center
Hampton Inn & Suites Houston Medical Center NRG Park

Hampton Inn & Suites Houston Medical Center NRG Park

2.5 out of 5
1715 Old Spanish Trl Houston TX
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $117 total per night from May 23 to May 24
$117 total
May 23 - May 24
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Guests will appreciate free perks like buffet breakfast and WiFi in public areas. Self parking, a business ...
Everything was nice and clean.

Reviewed on May 16, 2026

Opens in a new windowHampton Inn & Suites Houston Medical Center NRG Park
DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4 out of 5
6800 Main Street Houston TX
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $143 total per night from May 21 to May 22
$143 total
May 21 - May 22
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
The description says the place has been remodeled, but the rooms definitely are not. The parking lot is too small. The staff is so rude. Never staying here again!

Reviewed on May 14, 2026

Opens in a new windowDoubleTree by Hilton Houston Medical Center Hotel & Suites
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Texas Medical Center Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Texas Medical Center area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Texas Medical Center to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Texas Medical Center are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Texas Medical Center hotel reviews by fellow wanderers

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