Find a Hotel in Texas Medical Center

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Top hotels in Texas Medical Center

InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
Fully refundable
$173 nightly
The price is $203 total per night from Jan 18 to Jan 19
$203 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
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Reviewed on Jan 1, 2026

Opens in a new windowInterContinental Houston by IHG
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $153 total per night from Jan 18 to Jan 19
$153 total
Jan 18 - Jan 19
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
The hotel was wonderful. Excellent rooms and the lobby is stunning. Amazing staff; whether it’s the front desk or the valet crew, everyone was so friendly and helpful. Highly recommend this hotel.

Reviewed on Jan 2, 2026

Opens in a new windowBlossom Hotel Houston, Curio Collection by Hilton
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
Fully refundableReserve now, pay when you stay
$192 nightly
The price is $223 total per night from Jan 10 to Jan 11
$223 total
Jan 10 - Jan 11
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
It was good.

Reviewed on Jan 1, 2026

Opens in a new windowThe Westin Houston Medical Center/Museum District
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2 Houston TX
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $138 total per night from Jan 11 to Jan 12
$138 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy the hot tub ...
Clean rooms, friendly staff and great location.

Reviewed on Jan 2, 2026

Opens in a new windowHyatt Place Houston Medical Center
Hyatt House Houston Medical Center

Hyatt House Houston Medical Center

3 out of 5
7329 FANNIN STREET Houston TX
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $133 total per night from Jan 18 to Jan 19
$133 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like buffet breakfast and WiFi in public areas. You'll ...
Great place but not really pet friendly. Watch for the $100 pet fee

Reviewed on Jan 2, 2026

Opens in a new windowHyatt House Houston Medical Center
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $103 total per night from Jan 12 to Jan 13
$103 total
Jan 12 - Jan 13
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Very good location, the complementary coffe machine in the lobby was very nice. The room is clean and convenient

Reviewed on Dec 28, 2025

Opens in a new windowClub Quarters Hotel Downtown, Houston
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $129 total per night from Jan 8 to Jan 9
$129 total
Jan 8 - Jan 9
Total with taxes and fees
This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free ...
Species rooms, comfortable beds. Extra half bathroom is convenient.

Reviewed on Jan 2, 2026

Opens in a new windowHilton Houston Plaza/Medical Center
DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4 out of 5
6800 Main Street Houston TX
Fully refundableReserve now, pay when you stay
$83 nightly
The price is $97 total per night from Feb 1 to Feb 2
$97 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Only negative was at dinner the staff was overwhelmed by the amount of clientele

Reviewed on Jan 1, 2026

Opens in a new windowDoubleTree by Hilton Houston Medical Center Hotel & Suites
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
$130 nightly
The price is $152 total per night from Feb 3 to Feb 4
$152 total
Feb 3 - Feb 4
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like a free area shuttle. Valet parking, a business center, ...
Staff was great. Nice value for the $$

Reviewed on Jan 1, 2026

Opens in a new windowDoubleTree by Hilton Hotel & Suites Houston by the Galleria
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Texas Medical Center Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Texas Medical Center area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Texas Medical Center to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Texas Medical Center are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

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