Find a Hotel in Texas Medical Center

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Top hotels in Texas Medical Center

Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2 Houston TX
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $149 total per night from Apr 25 to Apr 26
$149 total
Apr 25 - Apr 26
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy the hot tub ...
clean comfortable rooms. shuttle service was a great service and saved time and frustration. shuttle driver was very courteous and friendly offering great recommendations for restaurants restaurant.was adequate and cocktails were good

Reviewed on Apr 16, 2026

Opens in a new windowHyatt Place Houston Medical Center
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $170 total per night from Apr 19 to Apr 20
$170 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Very pleasant stay with family. Courteous staff, good food, decent fitness center.

Reviewed on Apr 15, 2026

Opens in a new windowThe Westin Houston Medical Center/Museum District
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
Fully refundable
$180 nightly
The price is $211 total per night from May 17 to May 18
$211 total
May 17 - May 18
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
I've stayed at Intercontinental several times in the past including my honeymoon and have had a great experience. However, my experience at the Houston location wasn't as smooth. To start, the bell man was great, he was personable and was ready to help us. We had 4 big luggages and he was ready and ...

Reviewed on Apr 13, 2026

Opens in a new windowInterContinental Houston by IHG
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $160 total per night from May 17 to May 18
$160 total
May 17 - May 18
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
Perfection as usual!!

Reviewed on Apr 16, 2026

Opens in a new windowBlossom Hotel Houston, Curio Collection by Hilton
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
Fully refundableReserve now, pay when you stay
$237 nightly
The price is $277 total per night from Apr 19 to Apr 20
$277 total
Apr 19 - Apr 20
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...
This was such a wonderful experience from the booking, checkin, ambiance, the staff, and the peaceful rest that I received. I will definitely share with friends and plan to return.

Reviewed on Apr 15, 2026

Opens in a new windowHotel Zaza Houston Museum District
The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria

4 out of 5
2222 West Loop South Houston TX
$149 nightly
The price is $174 total per night from May 8 to May 9
$174 total
May 8 - May 9
Total with taxes and fees
This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, express check-out, ...
Pool area was a lil small, but the overall hotel is Great.

Reviewed on Apr 15, 2026

Opens in a new windowThe Royal Sonesta Houston Galleria
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $123 total per night from Apr 19 to Apr 20
$123 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
The place is nice but I have 2 mayor complaints that prevent me from staying there again. First parking. It’s non existent and did this is downtown. And you’ll have to pay 45 for valet or 28 park yourself 2 blocks away. They should include that on description of hotel. Second and worst, noise, lots ...

Reviewed on Apr 15, 2026

Opens in a new windowClub Quarters Hotel Downtown, Houston
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $117 total per night from Apr 26 to Apr 27
$117 total
Apr 26 - Apr 27
Total with taxes and fees
This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free ...
Was called handicap room, however my husband who is in a wheelchair, couldn’t get in shower and barely to toilet. No microwave in room, but they did bring one.

Reviewed on Apr 14, 2026

Opens in a new windowHilton Houston Plaza/Medical Center
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $139 total per night from Apr 24 to Apr 25
$139 total
Apr 24 - Apr 25
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like a free area shuttle. Valet parking, a business center, ...
Really a springhill suites with a name. Toilet didn’t work well

Reviewed on Apr 16, 2026

Opens in a new windowDoubleTree by Hilton Hotel & Suites Houston by the Galleria
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Texas Medical Center Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Texas Medical Center area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Texas Medical Center to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Texas Medical Center are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Texas Medical Center hotel reviews by fellow wanderers

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