Find a Hotel in Texas Medical Center

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top hotels in Texas Medical Center

Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2 Houston TX
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $149 total per night from Jul 12 to Jul 13
$149 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Parking was difficult and pricy. Check in staff on Sunday (the day I was supposed to check in) were rude and dismissive. The reservation I needed was Sunday June 28 to Wednesday July 1. Some how the dates were changed to check in on June 30 to July 3rd. My husband had appointments at MD Anderson ..."

Reviewed on Jul 4, 2026

Opens in a new windowHyatt Place Houston Medical Center
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
Fully refundableReserve now, pay when you stay
$154 nightly
The price is $178 total per night from Jul 11 to Jul 12
$178 total
Jul 11 - Jul 12
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
"It’s more of a Hampton Inn with the “Westin” logo on it. Arrived and the valet person was deeply sleeping. Perhaps even drunk. Don’t trust the $57 a night parking at all. Noisy, next to traffic and train station. Got a smaller room than what’s in the picture. Fridge door barely opens, blocked by ..."

Reviewed on Jul 3, 2026

Opens in a new windowThe Westin Houston Medical Center/Museum District
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
Fully refundable
$169 nightly
The price is $198 total per night from Jul 12 to Jul 13
$198 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"We had an amazing time in Houston despite the heat and humidity! We stayed for six nights, and our stay was truly memorable. The Club Lounge was a wonderful place to relax after busy days exploring the city and attending the World Cup. We especially appreciated the variety of food choices, which ..."

Reviewed on Jul 3, 2026

Opens in a new windowInterContinental Houston by IHG
Hyatt House Houston Medical Center

Hyatt House Houston Medical Center

3 out of 5
7329 FANNIN STREET Houston TX
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $149 total per night from Jul 12 to Jul 13
$149 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like buffet breakfast and WiFi in public areas. You'll ...
"Everything was great"

Reviewed on Jul 3, 2026

Opens in a new windowHyatt House Houston Medical Center
Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX

3 out of 5
6840 Almeda Rd Houston TX
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $125 total per night from Jul 12 to Jul 13
$125 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"The front desk staff are pretty unhelpful, especially if you’re arriving later in the night. I would advise calling them multiple times to make sure they have your listing. They removed my reservation despite calling them. They seemed to have no access to their own email, so if booking through a ..."

Reviewed on Jul 2, 2026

Opens in a new windowHilton Garden Inn Houston Medical Center, TX
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
Fully refundableReserve now, pay when you stay
$241 nightly
The price is $282 total per night from Jul 18 to Jul 19
$282 total
Jul 18 - Jul 19
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...
"Nice"

Reviewed on Jul 4, 2026

Opens in a new windowHotel Zaza Houston Museum District
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $172 total per night from Jul 12 to Jul 13
$172 total
Jul 12 - Jul 13
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
"Expected Staff to be more client satisfaction oriented"

Reviewed on Jul 5, 2026

Opens in a new windowBlossom Hotel Houston, Curio Collection by Hilton
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $93 total per night from Jul 18 to Jul 19
$93 total
Jul 18 - Jul 19
Total with taxes and fees
This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free ...
"Is ok for the price and ubication"

Reviewed on Jul 4, 2026

Opens in a new windowHilton Houston Plaza/Medical Center
Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl

2.5 out of 5
1301 Braeswood Blvd Houston TX
Fully refundableReserve now, pay when you stay
$83 nightly
The price is $97 total per night from Jul 12 to Jul 13
$97 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the free WiFi in public areas and onsite conference space. Guests will ...
"You have to ask for a remote because they get stolen. Our door had been pried open and there was a huge gap. Room was dirty. When we asked for towels we were told we needed to exchange our used for new. No maid service at all and the bed was the most uncomfortable I've ever slept it. Only plus was ..."

Reviewed on Jul 5, 2026

Opens in a new windowExtended Stay America Suites Houston Med Ctr Braeswood Bl
Don't see what you're looking for?
See all available properties in Texas Medical Center
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Texas Medical Center Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Texas Medical Center area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Texas Medical Center to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Texas Medical Center are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Texas Medical Center hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity