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Top hotels in Texas Medical Center

Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2 Houston TX
$127 nightly
The price is $149 total per night from Jul 5 to Jul 6
$149 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy the hot tub ...
"The shuttle van that will take you anywhere within two miles of the hotel was a nice amenity used by many patrons throughout the day!"

Reviewed on Jun 6, 2026

Opens in a new windowHyatt Place Houston Medical Center
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
Fully refundable
$186 nightly
The price is $218 total per night from Jul 5 to Jul 6
$218 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"Great stay, nice staff"

Reviewed on Jun 1, 2026

Opens in a new windowInterContinental Houston by IHG
Hyatt House Houston Medical Center

Hyatt House Houston Medical Center

3 out of 5
7329 FANNIN STREET Houston TX
$127 nightly
The price is $149 total per night from Jul 5 to Jul 6
$149 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like buffet breakfast and WiFi in public areas. You'll ...
"Staff was extremely helpful and so nice. The shuttle service was very convenient. Will definitely be staying there again."

Reviewed on Jun 4, 2026

Opens in a new windowHyatt House Houston Medical Center
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
Fully refundableReserve now, pay when you stay
$202 nightly
The price is $234 total per night from Jul 5 to Jul 6
$234 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
"Everything was great"

Reviewed on Jun 1, 2026

Opens in a new windowThe Westin Houston Medical Center/Museum District
Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX

3 out of 5
6840 Almeda Rd Houston TX
Fully refundableReserve now, pay when you stay
$142 nightly
The price is $166 total per night from Jul 5 to Jul 6
$166 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"It was an easy check-in process. The hotel grounds from front to back were clean including the parking garage."

Reviewed on Jun 7, 2026

Opens in a new windowHilton Garden Inn Houston Medical Center, TX
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$158 nightly
The price is $185 total per night from Jul 6 to Jul 7
$185 total
Jul 6 - Jul 7
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
"Everything was amazing and worth my money. Best experience from a hotel I’ve ever been to."

Reviewed on Jun 6, 2026

Opens in a new windowBlossom Hotel Houston, Curio Collection by Hilton
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $118 total per night from Jun 11 to Jun 12
$118 total
Jun 11 - Jun 12
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"The staff was helpful and kind. The property does show its age at times but it is maintained and kept clean. The valet staff is always top notch and respectful. Today it was raining upon check out and the staff escorted myself and my things to my vehicle with an umbrella to keep everything dry."

Reviewed on Jun 7, 2026

Opens in a new windowClub Quarters Hotel Downtown, Houston
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $117 total per night from Jul 5 to Jul 6
$117 total
Jul 5 - Jul 6
Total with taxes and fees
This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free ...
"This is an excellent hotel, great staff, rooms are excellent and close to local Red line tram and eateries in the Medical Center district"

Reviewed on Jun 6, 2026

Opens in a new windowHilton Houston Plaza/Medical Center
DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4 out of 5
6800 Main Street Houston TX
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $143 total per night from Jul 5 to Jul 6
$143 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Very relaxed stay, cleaned and very close and convenient to Houston Methodist Hospital."

Reviewed on Jun 3, 2026

Opens in a new windowDoubleTree by Hilton Houston Medical Center Hotel & Suites
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Texas Medical Center Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Texas Medical Center area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Texas Medical Center to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Texas Medical Center are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Texas Medical Center hotel reviews by fellow wanderers

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