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Top hotels in Texas Medical Center

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
Fully refundableReserve now, pay when you stay
$171 nightly
The price is $198 total per night from Apr 4 to Apr 5
$198 total
Apr 4 - Apr 5
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Everything was good

Reviewed on Mar 14, 2026

Opens in a new windowThe Westin Houston Medical Center/Museum District
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
Fully refundable
$186 nightly
The price is $218 total per night from Mar 29 to Mar 30
$218 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
We traveled to Houston for stockshow. We didn't know when exactly we would be showing and probably should have extended our stay sooner. However, we didn't and on the last day, they were unable to extend our reservation because they were over-booked. The manager was pretty rude about it. Didn't offer ...

Reviewed on Mar 17, 2026

Opens in a new windowInterContinental Houston by IHG
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $188 total per night from Mar 29 to Mar 30
$188 total
Mar 29 - Mar 30
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
2 night stay in the 2 room suite for our trip in for the Houston Livestock Show and Rodeo. 5 star experience from check in to check out. On had the hotel shuttle service take us to Rice Village to check out the shops and grab some dinner. It was so convenient and when we were ready a quick text to ...

Reviewed on Mar 17, 2026

Opens in a new windowBlossom Hotel Houston, Curio Collection by Hilton
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
Fully refundableReserve now, pay when you stay
$263 nightly
The price is $307 total per night from Apr 1 to Apr 2
$307 total
Apr 1 - Apr 2
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury aparthotel. Traveling on business? Take advantage of the 24-hour business ...
Although I had booked a Standard Room, 1 queen bed, I was placed in a petite queen. I must congratulate Hotel Zsa Zsa in providing me with the smallest hotel room that I have ever occupied. That includes many hotel rooms in Italy which has notoriously small rooms. If you have the slightest problem ...

Reviewed on Mar 15, 2026

Opens in a new windowHotel Zaza Houston Museum District
The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria

4 out of 5
2222 West Loop South Houston TX
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $168 total per night from Apr 2 to Apr 3
$168 total
Apr 2 - Apr 3
Total with taxes and fees
This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, express check-out, ...
Great place to stay during our visit for the Houston rodeo. Room was clean staff were courteous and available when help was required. Pool/hot tub area was smaller than expected. As we were here in March, not a lot of foot traffic at the pool but I'm sure if it was warmer this area would have been ...

Reviewed on Mar 17, 2026

Opens in a new windowThe Royal Sonesta Houston Galleria
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $133 total per night from Apr 5 to Apr 6
$133 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Location of this hotel is good. It is downtown and close proximity to Daikon Park and Toyota Center. The valet drop off pick up area is very confusing super busy at a very busy intersection that would be my chief complaint and of course, like most downtown towns of major cities, homeless people and ...

Reviewed on Mar 17, 2026

Opens in a new windowClub Quarters Hotel Downtown, Houston
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $117 total per night from Mar 29 to Mar 30
$117 total
Mar 29 - Mar 30
Total with taxes and fees
This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free ...
Phone didn’t work and AC wasn

Reviewed on Mar 16, 2026

Opens in a new windowHilton Houston Plaza/Medical Center
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $122 total per night from Apr 5 to Apr 6
$122 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like a free area shuttle. Valet parking, a business center, ...
Beautiful hotel, the staff is amazing, the cookies a plus plus!! The view, room, everything will definitely be back!

Reviewed on Mar 17, 2026

Opens in a new windowDoubleTree by Hilton Hotel & Suites Houston by the Galleria
Americas Best Value Inn NRG Park Medical Center

Americas Best Value Inn NRG Park Medical Center

2 out of 5
7905 Main St Houston TX
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $82 total per night from Mar 24 to Mar 25
$82 total
Mar 24 - Mar 25
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi, free self parking, and a free area shuttle. Staff at the 24-hour front desk can provide around-the-clock ...
The heater and a c word great.It was close to the stadium, like I wanted

Reviewed on Mar 17, 2026

Opens in a new windowAmericas Best Value Inn NRG Park Medical Center
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Texas Medical Center Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Texas Medical Center area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Texas Medical Center to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Texas Medical Center are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Texas Medical Center hotel reviews by fellow wanderers

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