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Top hotels in Texas Medical Center

InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
Fully refundable
$183 nightly
The price is $214 total per night from Feb 21 to Feb 22
$214 total
Feb 21 - Feb 22
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
The staff was very professional, and I love that my room, was clean and fresh. The only area that could’ve been better was my bathroom. It could’ve been mopped more thoroughly, and there was hair in the bathtub that wasn’t mine, which was noticeable. I’d recommend a final check during cleaning to ...

Reviewed on Feb 12, 2026

Opens in a new windowInterContinental Houston by IHG
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $188 total per night from Feb 22 to Feb 23
$188 total
Feb 22 - Feb 23
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
Excellent hotel and restaurant!

Reviewed on Feb 11, 2026

Opens in a new windowBlossom Hotel Houston, Curio Collection by Hilton
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2 Houston TX
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $149 total per night from Feb 21 to Feb 22
$149 total
Feb 21 - Feb 22
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy the hot tub ...
Nice, clean room. Spacious.

Reviewed on Feb 10, 2026

Opens in a new windowHyatt Place Houston Medical Center
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
Fully refundableReserve now, pay when you stay
$164 nightly
The price is $189 total per night from Feb 21 to Feb 22
$189 total
Feb 21 - Feb 22
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
I was advised that I would get a “special gift” e.g., free parking, bottle of wine…) Did not get anything

Reviewed on Feb 10, 2026

Opens in a new windowThe Westin Houston Medical Center/Museum District
Hyatt House Houston Medical Center

Hyatt House Houston Medical Center

3 out of 5
7329 FANNIN STREET Houston TX
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $153 total per night from Feb 21 to Feb 22
$153 total
Feb 21 - Feb 22
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like buffet breakfast and WiFi in public areas. You'll ...
Nice, big and spotless

Reviewed on Feb 11, 2026

Opens in a new windowHyatt House Houston Medical Center
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
Fully refundableReserve now, pay when you stay
$285 nightly
The price is $333 total per night from Feb 22 to Feb 23
$333 total
Feb 22 - Feb 23
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury aparthotel. Traveling on business? Take advantage of the 24-hour business ...
Compared to Memorial District, the Museum District was up to par in terms of the art & area. Will definitely stay here again if I am in the area.

Reviewed on Feb 5, 2026

Opens in a new windowHotel Zaza Houston Museum District
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $113 total per night from Feb 22 to Feb 23
$113 total
Feb 22 - Feb 23
Total with taxes and fees
This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free ...
Great room and super friendly staff. Breakfast each morning was a huge plus. The only complaints would be the lack of service on the tv and $20/day for parking. Overall very nice stay.

Reviewed on Feb 12, 2026

Opens in a new windowHilton Houston Plaza/Medical Center
The Whitehall Houston

The Whitehall Houston

4 out of 5
1700 Smith St Houston TX
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $167 total per night from Feb 22 to Feb 23
$167 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
It was clean and comfortable.

Reviewed on Feb 15, 2026

Opens in a new windowThe Whitehall Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $130 total per night from Feb 22 to Feb 23
$130 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like a free area shuttle. Valet parking, a business center, ...
Spotless and luxurious rooms. You have to pay for self parking and valet parking though.

Reviewed on Feb 15, 2026

Opens in a new windowDoubleTree by Hilton Hotel & Suites Houston by the Galleria
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Texas Medical Center Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Texas Medical Center area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Texas Medical Center to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Texas Medical Center are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

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