Find a Hotel in South Central Houston
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Top hotels in South Central Houston

Wanderstay Boutique Hotel
Reviewed on Sep 20, 2025

InterContinental Houston by IHG
Reviewed on Sep 20, 2025

The Westin Houston Medical Center/Museum District
Reviewed on Sep 21, 2025

Houston Marriott Medical Center/Museum District
Reviewed on Sep 15, 2025

Mint House Houston – Medical Center
Reviewed on Sep 12, 2025

Hotel Zaza Houston Museum District
Reviewed on Sep 15, 2025

Hilton University of Houston
Reviewed on Sep 20, 2025

Hilton Houston Plaza/Medical Center
Reviewed on Sep 22, 2025

DoubleTree by Hilton Houston Medical Center Hotel & Suites
Reviewed on Sep 22, 2025
South Central Houston Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on South Central Houston area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near South Central Houston to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near South Central Houston are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent South Central Houston hotel reviews by fellow wanderers

La Maison in Midtown an urban B&B
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