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Top Key Biscayne 5 Star hotels

Kimpton EPIC Hotel by IHG

Kimpton EPIC Hotel by IHG

5 out of 5
270 Biscayne Blvd Way Miami FL
Fully refundableReserve now, pay when you stay
$235 nightly
The price is $266 total per night from Jun 29 to Jun 30
$266 total
Jun 29 - Jun 30
Total with taxes and fees
This luxury hotel features a full-service spa, a marina, and 2 restaurants. Traveling on business? Take advantage of the 24-hour business center, free WiFi in ...
9/10 Wonderful! (2,507 reviews)
"Tranquilidad,"

Reviewed on Jun 7, 2026

Opens in a new windowKimpton EPIC Hotel by IHG
EAST Miami

EAST Miami

5 out of 5
788 Brickell Plaza Miami FL
Fully refundableReserve now, pay when you stay
$448 nightly
The price is $506 total per night from Jun 10 to Jun 11
$506 total
Jun 10 - Jun 11
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 4 outdoor pools, and a 24-hour gym. Relax with a drink at one of the 2 bars/lounges and get perks like free WiFi. ...
9.2/10 Wonderful! (3,850 reviews)
"Nice place"

Reviewed on Jun 8, 2026

Opens in a new windowEAST Miami
InterContinental Miami by IHG

InterContinental Miami by IHG

5 out of 5
100 Chopin Plz Miami FL
Fully refundable
$247 nightly
The price is $279 total per night from Jun 10 to Jun 11
$279 total
Jun 10 - Jun 11
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9.4/10 Exceptional! (2,501 reviews)
"We arrived off the cruise at 9:30. Check in was not until 3; however, the staff allowed us to check in at 10 with out an additional charge."

Reviewed on Jun 8, 2026

Opens in a new windowInterContinental Miami by IHG
The Miami Beach EDITION

The Miami Beach EDITION

5 out of 5
2901 Collins Ave Miami Beach FL
$604 nightly
The price is $689 total per night from Jun 9 to Jun 10
$689 total
Jun 9 - Jun 10
Total with taxes and fees
This luxury hotel features a full-service spa, a nightclub, and 5 restaurants. Traveling on business? Take advantage of the express check-in, express check-out, ...
9.2/10 Wonderful! (1,005 reviews)
"The hotel is amazing, great service. Nice pool and beach. Just make sure when you check in to make sure your room is not near the elevator it’s very noisy."

Reviewed on Jun 7, 2026

Opens in a new windowThe Miami Beach EDITION
Andaz Miami Beach Resort & Spa

Andaz Miami Beach Resort & Spa

5 out of 5
4041 Collins Ave Miami Beach FL
Fully refundableReserve now, pay when you stay
$359 nightly
The price is $409 total per night from Jun 28 to Jun 29
$409 total
Jun 28 - Jun 29
Total with taxes and fees
A full-service spa, 2 restaurants, and 2 outdoor pools are all featured at this luxury hotel. Relax with sun loungers and beach umbrellas, and cool off with ...
9/10 Wonderful! (305 reviews)
"The friendliness of the staff really stands out and should be commended The property and room was very clean and well maintained An ideal location Would definitely stay again"

Reviewed on Jun 7, 2026

Opens in a new windowAndaz Miami Beach Resort & Spa
1 Hotel South Beach

1 Hotel South Beach

5 out of 5
2341 Collins Avenue Miami Beach FL
Fully refundableReserve now, pay when you stay
$651 nightly
The price is $742 total per night from Jun 15 to Jun 16
$742 total
Jun 15 - Jun 16
Total with taxes and fees
A full-service spa, 3 restaurants, and 3 outdoor pools are all featured at this smoke-free hotel. Relax with beach cabanas, sun loungers, and beach umbrellas. ...
9.4/10 Exceptional! (1,540 reviews)
"Amazing service, amenities and ease of stay with the hospitality- a 10 out of 11! This is our only hotel brand/line that we WILL EVER do! Thank you!"

Reviewed on Jun 7, 2026

Opens in a new window1 Hotel South Beach
Nobu Hotel Miami Beach

Nobu Hotel Miami Beach

5 out of 5
4525 Collins Ave Miami Beach FL
Fully refundableReserve now, pay when you stay
$361 nightly
The price is $412 total per night from Jun 10 to Jun 11
$412 total
Jun 10 - Jun 11
Total with taxes and fees
A full-service spa, 2 restaurants, and 4 outdoor pools are all featured at this smoke-free resort. Relax with a drink at one of the 2 bars/lounges and get perks ...
Opens in a new windowNobu Hotel Miami Beach
Biltmore Hotel - Miami - Coral Gables

Biltmore Hotel - Miami - Coral Gables

5 out of 5
1200 Anastasia Ave Coral Gables FL
Fully refundableReserve now, pay when you stay
$318 nightly
The price is $357 total per night from Jul 7 to Jul 8
$357 total
Jul 7 - Jul 8
Total with taxes and fees
This luxury hotel features a golf course, a full-service spa, and 4 restaurants. Traveling on business? Take advantage of the business center, laundry service, ...
9.2/10 Wonderful! (1,006 reviews)
"Beautiful property, staff very responsive."

Reviewed on May 27, 2026

Opens in a new windowBiltmore Hotel - Miami - Coral Gables
W South Beach

W South Beach

5 out of 5
2201 Collins Avenue Miami Beach FL
Fully refundableReserve now, pay when you stay
$594 nightly
The price is $677 total per night from Jun 9 to Jun 10
$677 total
Jun 9 - Jun 10
Total with taxes and fees
A full-service spa, 2 outdoor pools, and a 24-hour gym are all featured at this luxury hotel. Relax with beach cabanas, sun loungers, and beach umbrellas. Traveling ...
9.2/10 Wonderful! (1,007 reviews)
"Room temperature amenities were good. Remote darkened room blind very nice."

Reviewed on Jun 7, 2026

Opens in a new windowW South Beach
The Ritz-Carlton, South Beach

The Ritz-Carlton, South Beach

5 out of 5
1 Lincoln Rd Miami Beach FL
$470 nightly
The price is $536 total per night from Jun 9 to Jun 10
$536 total
Jun 9 - Jun 10
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury resort. Relax with beach cabanas and sun loungers, and cool off with a ...
8.6/10 Excellent! (986 reviews)
"Great all round"

Reviewed on Jun 4, 2026

Opens in a new windowThe Ritz-Carlton, South Beach
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Key Biscayne Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Key Biscayne to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Key Biscayne 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Key Biscayne before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

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