Explore top 2026 4 Star Hotels in South Houston

Name: Hilton Houston NASA Clear Lake
Price range: $146 total
Rating: 8

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Top South Houston 4 Star hotels

Hotel Zaza Houston Museum District

5701 Main Street Houston TX

Fully refundableReserve now, pay when you stay

$271 nightly

$317 total

Jun 21 - Jun 22

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...

9.2/10 Wonderful! (1,008 reviews)

"Overall great hotel. Definitely will be staying here again. Shout out to the staff crew."

Reviewed on May 30, 2026

Club Quarters Hotel Downtown, Houston

1085 Rusk Street Houston TX

Fully refundableReserve now, pay when you stay

$111 nightly

$130 total

Jun 7 - Jun 8

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8.6/10 Excellent! (4,212 reviews)

"Staff was very friendly and helpful."

Reviewed on Jun 1, 2026

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

5353 Westheimer Rd Houston TX

Fully refundableReserve now, pay when you stay

$135 nightly

$158 total

Jun 7 - Jun 8

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like a free area shuttle. Valet parking, a business center, ...

8.4/10 Very Good! (4,107 reviews)

"loved the location and staff"

Reviewed on Jun 1, 2026

Hilton Houston Plaza/Medical Center

6633 Travis St Houston TX

Fully refundableReserve now, pay when you stay

$125 nightly

$146 total

Jun 6 - Jun 7

Total with taxes and fees

This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free ...

8.4/10 Very Good! (1,944 reviews)

"Clean, quite and spacious."

Reviewed on Jun 1, 2026

The Whitehall Houston

1700 Smith St Houston TX

Fully refundableReserve now, pay when you stay

$132 nightly

$154 total

Jun 21 - Jun 22

Total with taxes and fees

This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8.6/10 Excellent! (2,218 reviews)

"Great"

Reviewed on Jun 1, 2026

Blossom Hotel Houston, Curio Collection by Hilton

7118 Bertner Ave Houston TX

Fully refundableReserve now, pay when you stay

$183 nightly

$214 total

Jun 7 - Jun 8

Total with taxes and fees

A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

9/10 Wonderful! (3,841 reviews)

"Staff was great. Expect $50 parking. I didn’t know that was the case when I booked"

Reviewed on Jun 1, 2026

The Royal Sonesta Houston Galleria

2222 West Loop South Houston TX

$159 nightly

$186 total

Jun 7 - Jun 8

Total with taxes and fees

This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, express check-out, ...

8.6/10 Excellent! (1,966 reviews)

"Hotel"

Reviewed on Jun 1, 2026

DoubleTree by Hilton Hotel Houston - Greenway Plaza

Houston TX

Fully refundableReserve now, pay when you stay

$136 nightly

$159 total

Jun 10 - Jun 11

Total with taxes and fees

This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express ...

8.4/10 Very Good! (1,627 reviews)

"Disgusting rooms. Smelled liked mold and cigarettes either zero air conditioning prior to check in. We moved rooms several times and every room was gross."

Reviewed on Jun 1, 2026

Omni Houston Hotel

4 Riverway Houston TX

Fully refundableReserve now, pay when you stay

$174 nightly

$204 total

Jun 7 - Jun 8

Total with taxes and fees

A full-service spa, a nightclub, and 2 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

9.2/10 Wonderful! (1,008 reviews)

"This is a beautiful hotel in an excellent location with wonderful staff. Super great place for out of town guests for a wedding or a wedding itself!!"

Reviewed on Jun 1, 2026

Hilton Houston NASA Clear Lake

3000 Nasa Pkwy Houston TX

Fully refundableReserve now, pay when you stay

$125 nightly

$146 total

Jun 4 - Jun 5

Total with taxes and fees

This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

8/10 Very Good! (1,004 reviews)

"Shower drain didn't work well, no ventilation in bathroom. Bed was clean, pool was nice and had shade in afternoon. Breakfast buffet was decent but overpriced"

Reviewed on Jun 1, 2026

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4 Star Hotels South Houston

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in South Houston 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in South Houston will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in South Houston, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.