Explore top 2026 4 Star Hotels in South San Francisco

Name: Hotel Zephyr San Francisco
Price range: $208 total

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Top South San Francisco 4 Star hotels

Hotel Riu Plaza Fisherman's Wharf

2500 Mason St San Francisco CA

$159 nightly

$188 total

Nov 3 - Nov 4

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...

Hilton San Francisco Financial District

750 Kearny St San Francisco CA

Fully refundableReserve now, pay when you stay

$93 nightly

$110 total

Nov 8 - Nov 9

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and WiFi in public areas. Self ...

Grand Hyatt San Francisco

345 Stockton St San Francisco CA

Fully refundableReserve now, pay when you stay

$174 nightly

$205 total

Nov 6 - Nov 7

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

9/10 Wonderful! (1,015 reviews)

"Nice size room. Great location!"

Reviewed on Oct 8, 2026

DoubleTree by Hilton Hotel Berkeley Marina

200 Marina Blvd Berkeley CA

Fully refundableReserve now, pay when you stay

$145 nightly

$167 total

Nov 1 - Nov 2

Total with taxes and fees

A marina, a gym, and a restaurant are all featured at this traditional hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...

8.2/10 Very Good! (5,167 reviews)

"The main common use amenities looked great and well maintained. The room we had booked with a double bed was clearly in need of some attention. The bathtub was flooding and when attempting to fix it , hair and residue was stuck at the bottom. The sliding door was held shut with an old lock that didn’t ..."

Reviewed on Oct 8, 2026

Hyatt Regency San Francisco

5 Embarcadero Center San Francisco CA

Fully refundableReserve now, pay when you stay

$258 nightly

$304 total

Nov 6 - Nov 7

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...

9.2/10 Wonderful! (2,529 reviews)

"5 stars. Family has been staying at the locations for many years. My wife and I will be back soon. Just a fantastic experience."

Reviewed on Oct 9, 2026

Hyatt Regency San Francisco Downtown SOMA

50 3rd St San Francisco CA

Fully refundableReserve now, pay when you stay

$195 nightly

$229 total

Oct 30 - Oct 31

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, ...

9.4/10 Exceptional! (1,297 reviews)

"Every staff member we encountered was friendly, helpful and patient with my wife and I. We had some special needs that were essential for our stay and they were all pleasantly taken care of. Our room was very clean and met and exceeded our requests for our stay in SF. I would consider staying there ..."

Reviewed on Oct 9, 2026

Stanford Court San Francisco

905 California Street San Francisco CA

Fully refundableReserve now, pay when you stay

$243 nightly

$286 total

Oct 10 - Oct 11

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

Club Quarters Hotel Embarcadero, San Francisco

424 Clay St San Francisco CA

$126 nightly

$148 total

Oct 18 - Oct 19

Total with taxes and fees

A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. A coffee ...

Grand Hyatt at SFO

55 S McDonnell Rd San Francisco CA

Fully refundableReserve now, pay when you stay

$328 nightly

$366 total

Oct 24 - Oct 25

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet ...

Hotel Zephyr San Francisco

250 Beach Street San Francisco CA

Fully refundableReserve now, pay when you stay

$176 nightly

$208 total

Nov 9 - Nov 10

Total with taxes and fees

A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...

Don't see what you're looking for?

See all available properties in South San Francisco

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels South San Francisco

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in South San Francisco 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in South San Francisco will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in South San Francisco, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.