South San Francisco Vacation Packages 2025/2026 from $298

South San Francisco flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Bay Landing San Francisco Airport Hotel

Save 100% on your flight

per person

Sep 26 - Sep 30

found 1 day ago

Roundtrip flight included

Denver (DEN) to San Francisco (SFO)

This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free self parking, and a free airport shuttle. Business travelers can take advantage of the free WiFi in public areas. Enjoy the gym and conveniences like a 24-hour front desk and laundry facilities.

Embassy Hotel

Downtown San Francisco

Save 100% on your flight

per person

Sep 26 - Sep 30

found 1 day ago

Roundtrip flight included

Denver (DEN) to San Francisco (SFO)

This hotel features free WiFi in public areas, concierge services, and valet parking. A hair salon, a computer station, and luggage storage are also on offer.

The Donatello

Union Square

per person

Sep 24 - Oct 1

found 1 day ago

Roundtrip flight included

Denver (DEN) to San Francisco (SFO)

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, and valet parking. Enjoy the sauna and conveniences like a 24-hour front desk and concierge services.

The Grove Inn

Western Addition

Save 100% on your flight

per person

Sep 15 - Sep 18

found 1 day ago

Roundtrip flight included

Denver (DEN) to San Francisco (SFO)

Free WiFi in public areas, a communal living room, and express check-in are available at this hotel. A business center, express check-out, and luggage storage are also on offer.

Chancellor Hotel on Union Square

Union Square

Save 100% on your flight

per person

Sep 26 - Sep 30

found 1 day ago

Roundtrip flight included

Denver (DEN) to San Francisco (SFO)

This hotel features a bar/lounge, free WiFi in public areas, and dry cleaning. There's luggage storage and multilingual staff can provide around-the-clock assistance.

Top South San Francisco hotels deals

Best Western Plus Grosvenor Airport Hotel

380 S Airport Boulevard, South San Francisco, CA

Free Cancellation

Reserve now, pay when you stay

$120 nightly

$141 total

Jul 26 - Jul 27

Total includes taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Self parking, a library, and express check-in are also offered.

Breakfast included

Free airport shuttle

Sonesta Select San Francisco Airport Oyster Point Waterfront

1300 Veterans Blvd, South San Francisco, CA

Free Cancellation

Reserve now, pay when you stay

$108 nightly

$129 total

Aug 10 - Aug 11

Total includes taxes and fees

This hotel features a 24-hour gym and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, and free airport shuttle. Self parking, a coffee shop, and a snack bar/deli are also offered.

Free airport shuttle

Pet friendly

DoubleTree by Hilton San Francisco South Airport Blvd

275 S Airport Blvd, South San Francisco, CA

Free Cancellation

Reserve now, pay when you stay

$123 nightly

$145 total

Aug 10 - Aug 11

Total includes taxes and fees

This hotel features a gym and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Self parking, a garden, and a grocery/convenience store are also offered.

Free airport shuttle

Pet friendly

La Quinta Inn & Suites by Wyndham San Francisco Airport N

20 Airport Blvd, South San Francisco, CA

Free Cancellation

Reserve now, pay when you stay

$125 nightly

$146 total

Jul 28 - Jul 29

Total includes taxes and fees

This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Free continental breakfast is served.

Pool

Breakfast included

Holiday Inn Golden Gateway by IHG

1500 Van Ness Ave, San Francisco, CA

Free Cancellation

$139 nightly

$164 total

Aug 17 - Aug 18

Total includes taxes and fees

This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's a bar/lounge on site, and a 24-hour front desk and laundry facilities are also provided.

Pool

Free WiFi

Hotel Riu Plaza Fisherman's Wharf

2500 Mason St, San Francisco, CA

Free Cancellation

Reserve now, pay when you stay

$157 nightly

$185 total

Jul 28 - Jul 29

Total includes taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the 24-hour gym and free buffet breakfast each morning.

Pool

Breakfast included

Don't see what you're looking for?

See all available properties in South San Francisco

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Golden Gate Park

4.5/5(5,122 reviews)

This beloved park offers relaxation among trees, flowers and wildlife, right in San Francisco’s backyard.

Pier 39

4.5/5(6,817 reviews)

This waterfront attraction offers thrilling rides, innovative street performers and colorful souvenir shops, but it’s the sea lions that win the day.

Golden Gate Bridge

4.5/5(7,244 reviews)

Cars trundle across it and ships sail under it, but the best way to experience this iconic bridge is on foot.

Frequently asked questions

How much are vacation packages to South San Francisco?

Travelocity has great package deals to South San Francisco, including flights and hotels, from an impressive $298. With all that extra money, you could book some cool tours or possibly tack on a few extra nights to your vacation.

How long should my South San Francisco vacation be?

The majority of travelers book their hotel for 2 nights in South San Francisco. But that doesn't mean you're limited to that. How long you choose to stay really comes down to how much you want to do during your vacation. If you'd like to explore every nook and cranny of this wonderful place, consider booking another night or two (or even longer!).

Where can I get the best vacation package deals for South San Francisco?

Travelocity has everything you need to score a terrific South San Francisco package deal. Take your pick of 400 partner airlines and 1,000,000 properties all over the globe and create a vacation package that's perfect for you. With almost endless choice, it's time to start planning your next big getaway.

Why should I purchase my South San Francisco vacation package via Travelocity?

We offer round-the-clock support, superb service and a Price Match Guarantee. Life is one big journey — and we have enticing destinations for you to journey to all over the world. Travel with us and your bank balance will thank you for it.

Will I save money on my South San Francisco car rental if I book it with a hotel or flight?

With a South San Francisco vacation package, you can combine your hotel, car and flight bookings and save a ton. If you're eager to see the best of this awesome city, why not head to Monterey Bay Aquarium? This renowned sight is 75 mi from South San Francisco. With a rental car, you'll be there in the blink of an eye.

Which airport is best for South San Francisco?

One of your top options is San Francisco Intl. Airport (SFO), which is situated 3 mi south of downtown South San Francisco. Another choice is Oakland Intl. Airport (OAK), 11 mi away from central South San Francisco).

What is there to do in South San Francisco?

There's a certain magic in the air as you stroll through the streets of South San Francisco. K1 Speed San Francisco and See's Candies are just a couple of renowned sights that make this city so special, so add them to your itinerary.

Where should I stay when visiting South San Francisco?

The La Quinta Inn & Suites by Wyndham San Francisco Airport N is popular with many travelers. Book soon to avoid missing out.