Explore top 2025 5 Star Hotels in Downtown San Francisco

Name: The St. Regis San Francisco
Price range: $587 total

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Top Downtown San Francisco 5 Star hotels

Fairmont San Francisco

950 Mason Street Atop Nob Hill, San Francisco, CA

Fully refundableReserve now, pay when you stay

$332 nightly

$391 total

Sep 22 - Sep 23

Total with taxes and fees

A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, express ...

Taj Campton Place

340 Stockton St, San Francisco, CA

Fully refundableReserve now, pay when you stay

$208 nightly

$244 total

Sep 6 - Sep 7

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

Palace Hotel, a Luxury Collection Hotel, San Francisco

2 New Montgomery St, San Francisco, CA

Fully refundableReserve now, pay when you stay

$309 nightly

$364 total

Sep 6 - Sep 7

Total with taxes and fees

This smoke-free hotel includes 2 restaurants, an indoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

The Ritz-Carlton, San Francisco

600 Stockton St, San Francisco, CA

Fully refundableReserve now, pay when you stay

$452 nightly

$531 total

Sep 27 - Sep 28

Total with taxes and fees

This luxury hotel features 2 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...

Four Seasons Hotel San Francisco

757 Market St, San Francisco, CA

Fully refundableReserve now, pay when you stay

$415 nightly

$488 total

Oct 2 - Oct 3

Total with taxes and fees

A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Families will appreciate kid-friendly dining and in-room childcare. Enjoy ...

1 Hotel San Francisco

8 Mission St, San Francisco, CA

Fully refundableReserve now, pay when you stay

$394 nightly

$464 total

Sep 26 - Sep 27

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the in-room fitness and perks like free WiFi. There's a ...

Four Seasons Hotel San Francisco at Embarcadero

222 Sansome St, San Francisco, CA

Fully refundableReserve now, pay when you stay

$455 nightly

$535 total

Sep 26 - Sep 27

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Families will appreciate the onsite laundry facilities and in-room childcare. Traveling on ...

The St. Regis San Francisco

125 3rd St, San Francisco, CA

Fully refundableReserve now, pay when you stay

$498 nightly

$587 total

Oct 3 - Oct 4

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.