Explore top 2026 4 Star Hotels in South San Francisco

Name: Hilton San Francisco Airport Bayfront
Price range: $130 total
Rating: 8.6

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Top South San Francisco 4 Star hotels

Hyatt Regency San Francisco

5 Embarcadero Center San Francisco CA

$218 nightly

$257 total

Mar 7 - Mar 8

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...

9.2/10 Wonderful! (2,094 reviews)

The best

Reviewed on Feb 27, 2026

DoubleTree by Hilton Hotel Berkeley Marina

200 Marina Blvd Berkeley CA

Fully refundableReserve now, pay when you stay

$112 nightly

$129 total

Mar 8 - Mar 9

Total with taxes and fees

A marina, a gym, and a restaurant are all featured at this traditional hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...

8.2/10 Very Good! (4,304 reviews)

The building is very old and so dark; the hallway smells. They need to change the carpet in the hallway and the room. Staff is not friendly at all they don't even say hello if you see them in a hallway, house keeper keep coming in to my room even I put up a sign. Very disappointed

Reviewed on Feb 28, 2026

Hotel Riu Plaza Fisherman's Wharf

2500 Mason St San Francisco CA

Fully refundableReserve now, pay when you stay

$176 nightly

$208 total

Mar 3 - Mar 4

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...

9/10 Wonderful! (7,324 reviews)

Clean comfortable rooms and excellent customer servic.e.

Reviewed on Feb 28, 2026

Hilton San Francisco Financial District

750 Kearny St San Francisco CA

$111 nightly

$130 total

Mar 29 - Mar 30

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and WiFi in public areas. Self ...

8.8/10 Excellent! (2,445 reviews)

The lighting throughout the room was very fluorescent white and not pleasant. The elevator takes a long time and stops at too many floors

Reviewed on Feb 27, 2026

Club Quarters Hotel in San Francisco

424 Clay St San Francisco CA

$110 nightly

$129 total

Mar 29 - Mar 30

Total with taxes and fees

A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. A coffee ...

9/10 Wonderful! (2,974 reviews)

The staff at reception are always so welcoming. I arrived quite early and they securely held my bags until check-in. They collaborated to find a room which was suitable for my stay. The lobby was a bit crowded at times, but the hotel was fully booked, so...understandable.

Reviewed on Feb 27, 2026

InterContinental Mark Hopkins by IHG

999 California Street San Francisco CA

Fully refundable

$211 nightly

$248 total

Mar 29 - Mar 30

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...

9/10 Wonderful! (1,328 reviews)

A little dated but the staff was amazing

Reviewed on Feb 28, 2026

Kimpton Alton Fisherman's Wharf by IHG

2700 JONES STREET San Francisco CA

$184 nightly

$217 total

Mar 30 - Mar 31

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. WiFi in public areas is free. Valet parking, a coffee shop, and dry cleaning are also ...

9.2/10 Wonderful! (1,521 reviews)

Staff were super friendly, informative and helpful. Quick check in & check out process. Room was clean and honestly couldn't hear any noise either from the road or from any neighbors. Housekeepers were kind and also very friendly, attentive every day. Impressed with the restaurant in the lobby, also ...

Reviewed on Feb 23, 2026

Grand Hyatt at SFO

55 S McDonnell Rd San Francisco CA

Fully refundableReserve now, pay when you stay

$289 nightly

$323 total

Mar 7 - Mar 8

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet ...

9.8/10 Exceptional! (1,509 reviews)

We had tarmac views feom our room and yet it was quiet!! I sat and watched luggage trains, planes, trucks in silence. The room was clean, beds were comfortable and rhe staa friendly!

Reviewed on Feb 27, 2026

Oakland Marriott City Center

1001 Broadway Oakland CA

Fully refundableReserve now, pay when you stay

$112 nightly

$130 total

Mar 8 - Mar 9

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

9/10 Wonderful! (1,001 reviews)

The view was the best. Everything else was good. Wish I got complimentary breakfast for that price.

Reviewed on Feb 24, 2026

Hilton San Francisco Airport Bayfront

600 Airport Boulevard Burlingame CA

Fully refundableReserve now, pay when you stay

$114 nightly

$130 total

Mar 15 - Mar 16

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8.6/10 Excellent! (2,920 reviews)

It was ok, about what i expected. It was clean and close to the airport.

Reviewed on Feb 27, 2026

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4 Star Hotels South San Francisco

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in South San Francisco 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in South San Francisco will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in South San Francisco, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.