Explore top 2025 4 Star Hotels in South San Francisco

Name: Hilton San Francisco Airport Bayfront
Price range: $106 total
Rating: 8.4

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Top South San Francisco 4 Star hotels

Hyatt Regency San Francisco

5 Embarcadero Center San Francisco CA

Fully refundableReserve now, pay when you stay

$183 nightly

$215 total

Dec 14 - Dec 15

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...

9.2/10 Wonderful! (1,970 reviews)

Room is excellent

Reviewed on Nov 20, 2025

DoubleTree by Hilton Hotel Berkeley Marina

200 Marina Blvd Berkeley CA

Fully refundableReserve now, pay when you stay

$147 nightly

$170 total

Nov 30 - Dec 1

Total with taxes and fees

A marina, a gym, and a restaurant are all featured at this traditional hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...

8.2/10 Very Good! (3,784 reviews)

Nice room. Got Chocolate Chip Walnut cookies that were better than any cookie I've eaten within 5000 miles of here.

Reviewed on Nov 21, 2025

Hotel Riu Plaza Fisherman's Wharf

2500 Mason St San Francisco CA

Fully refundableReserve now, pay when you stay

$148 nightly

$174 total

Nov 24 - Nov 25

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...

8.8/10 Excellent! (7,114 reviews)

Very good service.

Reviewed on Nov 17, 2025

Hilton San Francisco Financial District

750 Kearny St San Francisco CA

Fully refundableReserve now, pay when you stay

$93 nightly

$109 total

Dec 22 - Dec 23

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and WiFi in public areas. Self ...

8.6/10 Excellent! (2,017 reviews)

Best ever thank you

Reviewed on Nov 17, 2025

Club Quarters Hotel in San Francisco

424 Clay St San Francisco CA

Fully refundableReserve now, pay when you stay

$97 nightly

$114 total

Nov 23 - Nov 24

Total with taxes and fees

A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. A coffee ...

8.8/10 Excellent! (2,746 reviews)

Good

Reviewed on Nov 19, 2025

InterContinental Mark Hopkins by IHG

999 California Street San Francisco CA

Fully refundable

$170 nightly

$200 total

Nov 25 - Nov 26

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...

9/10 Wonderful! (1,184 reviews)

The room had lovely views, a nice long corridor as you enter the room. The bed was well appointed and comfortable. The staff was pleasant and accommodating.

Reviewed on Nov 20, 2025

Kimpton Alton Fisherman's Wharf by IHG

2700 JONES STREET San Francisco CA

Fully refundable

$146 nightly

$172 total

Nov 30 - Dec 1

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. WiFi in public areas is free. Valet parking, a coffee shop, and dry cleaning are also ...

9/10 Wonderful! (1,528 reviews)

Friendly staff

Reviewed on Nov 18, 2025

Grand Hyatt at SFO

55 S McDonnell Rd San Francisco CA

Fully refundableReserve now, pay when you stay

$289 nightly

$323 total

Dec 22 - Dec 23

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet ...

9.6/10 Exceptional! (1,445 reviews)

Safety , rooms were clean, beds comfortable drinks good as well as the food. A little pricey

Reviewed on Nov 18, 2025

Oakland Marriott City Center

1001 Broadway Oakland CA

Fully refundableReserve now, pay when you stay

$111 nightly

$129 total

Dec 14 - Dec 15

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8.8/10 Excellent! (1,010 reviews)

Parking price is ridiculous

Reviewed on Nov 21, 2025

Hilton San Francisco Airport Bayfront

600 Airport Boulevard Burlingame CA

Fully refundableReserve now, pay when you stay

$93 nightly

$106 total

Dec 14 - Dec 15

Total with taxes and fees

This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8.4/10 Very Good! (2,711 reviews)

Room was great, staff was wonderful

Reviewed on Nov 20, 2025

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4 Star Hotels South San Francisco

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in South San Francisco 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in South San Francisco will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in South San Francisco, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.