Explore top 2026 4 Star Hotels in Missouri City

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Top Missouri City 4 Star hotels

Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $124 total per night from May 19 to May 20
$124 total
May 19 - May 20
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.6/10 Excellent! (4,156 reviews)
Great

Reviewed on May 12, 2026

Opens in a new windowClub Quarters Hotel Downtown, Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
Fully refundableReserve now, pay when you stay
$153 nightly
The price is $179 total per night from May 29 to May 30
$179 total
May 29 - May 30
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like a free area shuttle. Valet parking, a business center, ...
8.4/10 Very Good! (4,007 reviews)
The room had roaches in the bathroom and the toilet wouldn’t flush properly. Maintenance came to fix but it still wouldn’t work properly.

Reviewed on May 12, 2026

Opens in a new windowDoubleTree by Hilton Hotel & Suites Houston by the Galleria
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $110 total per night from May 25 to May 26
$110 total
May 25 - May 26
Total with taxes and fees
This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free ...
8.4/10 Very Good! (1,918 reviews)
Great hotel with wonderful location and very accommodating staff. There were some cosmetic issues with room. Overall enjoyed our stay.

Reviewed on May 12, 2026

Opens in a new windowHilton Houston Plaza/Medical Center
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
Fully refundableReserve now, pay when you stay
$223 nightly
The price is $261 total per night from May 27 to May 28
$261 total
May 27 - May 28
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...
9/10 Wonderful! (1,022 reviews)
No breakfast instead a good coffee bar

Reviewed on May 12, 2026

Opens in a new windowHotel Zaza Houston Museum District
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $188 total per night from May 24 to May 25
$188 total
May 24 - May 25
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9/10 Wonderful! (3,849 reviews)
Staff and Valet were both very helpful. Breakfast is pretty good , typical buffet style. Room was very clean and updated

Reviewed on May 11, 2026

Opens in a new windowBlossom Hotel Houston, Curio Collection by Hilton
The Whitehall Houston

The Whitehall Houston

4 out of 5
1700 Smith St Houston TX
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $186 total per night from May 24 to May 25
$186 total
May 24 - May 25
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.6/10 Excellent! (2,201 reviews)
Staff was very friendly

Reviewed on May 12, 2026

Opens in a new windowThe Whitehall Houston
The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria

4 out of 5
2222 West Loop South Houston TX
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $186 total per night from May 14 to May 15
$186 total
May 14 - May 15
Total with taxes and fees
This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, express check-out, ...
8.6/10 Excellent! (1,902 reviews)
Great

Reviewed on May 11, 2026

Opens in a new windowThe Royal Sonesta Houston Galleria
Grand Tuscany Hotel

Grand Tuscany Hotel

4 out of 5
12801 Northwest Fwy Houston TX
$89 nightly
The price is $104 total per night from May 19 to May 20
$104 total
May 19 - May 20
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Families will appreciate the lazy river and picnic area. Enjoy the seasonal outdoor pool and perks ...
7.6/10 Good! (39 reviews)
Everything was good. Had to ask several times before finally receiving fresh towels. My only complaint was pool wasn't heated and needed to be cleaned.

Reviewed on May 10, 2026

Opens in a new windowGrand Tuscany Hotel
Omni Houston Hotel

Omni Houston Hotel

4 out of 5
4 Riverway Houston TX
Fully refundableReserve now, pay when you stay
$177 nightly
The price is $207 total per night from May 17 to May 18
$207 total
May 17 - May 18
Total with taxes and fees
A full-service spa, a nightclub, and 2 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9.2/10 Wonderful! (1,018 reviews)
The rooms are clean for the most part , I wouldn’t say they’re paying attention to every little detail. There was hair through out our restroom, and a stained bed skirt.

Reviewed on May 12, 2026

Opens in a new windowOmni Houston Hotel
DoubleTree by Hilton Hotel Houston - Greenway Plaza

DoubleTree by Hilton Hotel Houston - Greenway Plaza

4 out of 5
Houston TX
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $135 total per night from May 21 to May 22
$135 total
May 21 - May 22
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express ...
8.4/10 Very Good! (1,586 reviews)
I didn’t get to utilize the shuttle. It was either one driver working or it doesn’t run at certain times.

Reviewed on May 11, 2026

Opens in a new windowDoubleTree by Hilton Hotel Houston - Greenway Plaza
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4 Star Hotels Missouri City

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Missouri City 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Missouri City will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Missouri City, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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