Book Hotels in North Central San Diego, CA

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight
Sep 26 - Sep 27
Tomorrow
Sep 27 - Sep 28
This weekend
Sep 26 - Sep 28
Next weekend
Oct 3 - Oct 5

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top North Central San Diego hotels

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
Fully refundableReserve now, pay when you stay
$266 nightly
The price is $308 total per night from Oct 4 to Oct 5
$308 total
Oct 4 - Oct 5
Total with taxes and fees
This eco-certified hotel includes 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi ...
"The hotel is nice but more tailored for the convention fare & less of a resort ambiance. Service was efficient yet impersonal & why no concierge? They make a hotel experience."

Reviewed on Sep 22, 2025

Opens in a new windowManchester Grand Hyatt San Diego
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $160 total per night from Sep 28 to Sep 29
$160 total
Sep 28 - Sep 29
Total with taxes and fees
A marina, a gym, and a restaurant are all featured at this traditional hotel. Traveling on business? Take advantage of the free WiFi in public areas and free ...
"Great calm place"

Reviewed on Sep 25, 2025

Opens in a new windowBay Club Hotel & Marina
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
$165 nightly
The price is $190 total per night from Oct 26 to Oct 27
$190 total
Oct 26 - Oct 27
Total with taxes and fees
A marina, 2 outdoor pools, and 2 hot tubs are all featured at this smoke-free hotel. If you want to take your pet along, this pet-friendly property offers everything ...
"good"

Reviewed on Sep 24, 2025

Opens in a new windowThe Dana on Mission Bay
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave, San Diego, CA
Fully refundableReserve now, pay when you stay
$269 nightly
The price is $311 total per night from Sep 28 to Sep 29
$311 total
Sep 28 - Sep 29
Total with taxes and fees
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free ...
"Perfect stay"

Reviewed on Sep 25, 2025

Opens in a new windowHard Rock Hotel San Diego
Palihotel San Diego Gaslamp Quarter

Palihotel San Diego Gaslamp Quarter

4 out of 5
830 Sixth Avenue, San Diego, CA
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $122 total per night from Oct 21 to Oct 22
$122 total
Oct 21 - Oct 22
Total with taxes and fees
This hotel features a restaurant and 2 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and dry cleaning are also offered.
"My husband and I stayed for one night. The hotel is so beautiful and we loved the rooftop view. The only complaint we have is there was this incessant tapping coming from the heater at night which made it impossible to sleep. We had a long drive the next day so that was extra annoying"

Reviewed on Sep 20, 2025

Opens in a new windowPalihotel San Diego Gaslamp Quarter
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue, San Diego, CA
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $138 total per night from Oct 2 to Oct 3
$138 total
Oct 2 - Oct 3
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"I would definitely stay here again! Clean room, nice and accommodating staff. Less than 10 minutes away from airport and restaurants."

Reviewed on Sep 25, 2025

Opens in a new windowThe DEXTRO Little Italy, BW Premier Collection
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive, San Diego, CA
Fully refundableReserve now, pay when you stay
$177 nightly
The price is $205 total per night from Sep 29 to Sep 30
$205 total
Sep 29 - Sep 30
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, express check-out, and ...
"Beautiful San Diego. Beautiful view from the balcony of Wyndham Bay Side. Everything easily accessible."

Reviewed on Sep 23, 2025

Opens in a new windowWyndham San Diego Bayside
DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar

4 out of 5
11915 El Camino Real, San Diego, CA
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $133 total per night from Oct 13 to Oct 14
$133 total
Oct 13 - Oct 14
Total with taxes and fees
This hotel features an outdoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 9 conference rooms, free WiFi in public areas, ...
"Loved area convenient and very safe!"

Reviewed on Sep 24, 2025

Opens in a new windowDoubleTree by Hilton San Diego - Del Mar
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $116 total per night from Sep 30 to Oct 1
$116 total
Sep 30 - Oct 1
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
Nice hotel
"The hotel was very nice, if a little dated, with a really nice pool area! It felt safe and I slept well here! The air conditioner was quiet which is a bonus in any hotel!"

Reviewed on Sep 25, 2025

Opens in a new windowHandlery Hotel
Don't see what you're looking for?
See all available properties in North Central San Diego
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap North Central San Diego hotels

La Quinta Inn by Wyndham San Diego - Miramar

La Quinta Inn by Wyndham San Diego - Miramar

10185 Paseo Montril, San Diego, CA
$86 nightly
The price is $99 total per night from Oct 5 to Oct 6
$99 total
Oct 5 - Oct 6
Total with taxes and fees
7.6/10 Good! (1,035 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent North Central San Diego hotel reviews by fellow wanderers

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

5 out of 5
Posted 19 hours ago
Travelocity Verified Review
"I would definitely stay here again! Clean room, nice and accommodating staff. Less than 10 minutes away from airport and restaurants."
A verified traveler stayed at The DEXTRO Little Italy, BW Premier Collection
The DEXTRO Little Italy, BW Premier Collection
Explore More Ways to Travel with Travelocity

Explore More Ways to Travel with Travelocity