Explore top 2026 4 Star Hotels in St. Charles

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Top St. Charles 4 Star hotels

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $179 total per night from Jun 14 to Jun 15
$179 total
Jun 14 - Jun 15
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
8.6/10 Excellent! (4,115 reviews)
"So.....I booked this hotel because parking was included. When we arrived at about 4:30 (check in was 4:00) they told us it was mandatory valet parking and it was $50.00. We had no option. Upon checkout - we had to wait in line over 1/2 hour for our vehicle to be retrieved standing in a hot garage. ..."

Reviewed on Jun 9, 2026

Opens in a new windowHyatt Regency St. Louis at The Arch
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $179 total per night from Jul 5 to Jul 6
$179 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.8/10 Excellent! (723 reviews)
"Dinning and pool areas were enjoyable."

Reviewed on Jun 2, 2026

Opens in a new windowLe Méridien St. Louis Clayton
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $189 total per night from Jun 21 to Jun 22
$189 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
9.4/10 Exceptional! (1,214 reviews)
"Our room was very clean. We would have loved a walk-in bathtub/shower, a microwave would have been more useful than a safe in the room. It was great overall."

Reviewed on Jun 8, 2026

Opens in a new windowLive by Loews - St.Louis
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $158 total per night from Jun 28 to Jun 29
$158 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
8.4/10 Very Good! (1,102 reviews)
"Location was not good. Clean rooms, nice staff and good breakfast."

Reviewed on Jun 8, 2026

Opens in a new windowRenaissance St. Louis Airport Hotel
Marriott St. Louis Grand

Marriott St. Louis Grand

4 out of 5
800 Washington Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $181 total per night from Jun 18 to Jun 19
$181 total
Jun 18 - Jun 19
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.2/10 Very Good! (1,020 reviews)
"The hallway wreaked of marijuana. Our room didn’t have a bar of soap upon checking. Upon requesting feather free pillows the staff brought us feather pillows. Lack of attention to detail."

Reviewed on Jun 7, 2026

Opens in a new windowMarriott St. Louis Grand
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
$165 nightly
The price is $193 total per night from Jun 21 to Jun 22
$193 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9/10 Wonderful! (1,896 reviews)
"A great time!! Everyone was so friendly!!"

Reviewed on Jun 8, 2026

Opens in a new window21C Museum Hotel St Louis
 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

4.5 out of 5
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$218 nightly
The price is $257 total per night from Jun 21 to Jun 22
$257 total
Jun 21 - Jun 22
Total with taxes and fees
This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
9/10 Wonderful! (1,012 reviews)
"Nice old school hotel. Great gym !!! Nice pool, not sure why they don’t have a jacuzzi . All in all very nice and old school and right next to the park."

Reviewed on Jun 8, 2026

Opens in a new window The Royal Sonesta Chase Park Plaza St. Louis
River City Casino & Hotel

River City Casino & Hotel

4 out of 5
777 River City Casino Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $113 total per night from Jun 29 to Jun 30
$113 total
Jun 29 - Jun 30
Total with taxes and fees
This hotel features a casino, a nightclub, and 5 restaurants. Traveling on business? Take advantage of the business center, conference center, and conference ...
9/10 Wonderful! (1,611 reviews)
"From the beginning of my arrival to the end of my trip was wonderful..casino was great had my machines..great time"

Reviewed on Jun 8, 2026

Opens in a new windowRiver City Casino & Hotel
Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark

4 out of 5
1 S Broadway St. Louis MO
Fully refundableReserve now, pay when you stay
$171 nightly
The price is $204 total per night from Jun 18 to Jun 19
$204 total
Jun 18 - Jun 19
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an indoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
7.6/10 Good! (1,162 reviews)
"Huge place! For the price rooms were nothing special, small. The shower was scalding hot very hard to get it to a temperature that didn’t leave burns! Valet and bellman were very nice and very helpful. Room temperature was hard to keep cool."

Reviewed on Jun 8, 2026

Opens in a new windowHilton St. Louis at the Ballpark
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4 out of 5
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $136 total per night from Jun 28 to Jun 29
$136 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
8.8/10 Excellent! (1,296 reviews)
"It was nice and great location. René ta was super helpful!!!"

Reviewed on Jun 8, 2026

Opens in a new windowMagnolia Hotel St. Louis, a Tribute Portfolio Hotel
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4 Star Hotels St. Charles

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in St. Charles 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in St. Charles will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in St. Charles, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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