Explore top 2025 4 Star Hotels in St. Louis

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Top St. Louis 4 Star hotels

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St, St. Louis, MO
$99 nightly
The price is $117 total per night from Nov 23 to Nov 24
$117 total
Nov 23 - Nov 24
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
8.4/10 Very Good! (3,996 reviews)
Staff was courteous and warm. Great location and clean room.

Reviewed on Nov 8, 2025

Opens in a new windowHyatt Regency St. Louis at The Arch
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4 out of 5
421 N 8th St, St. Louis, MO
$88 nightly
The price is $104 total per night from Nov 13 to Nov 14
$104 total
Nov 13 - Nov 14
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
8.6/10 Excellent! (1,096 reviews)
Really nice hotel!

Reviewed on Nov 5, 2025

Opens in a new windowMagnolia Hotel St. Louis, a Tribute Portfolio Hotel
St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton

4 out of 5
1820 Market Street, St. Louis, MO
$139 nightly
The price is $165 total per night from Nov 23 to Nov 24
$165 total
Nov 23 - Nov 24
Total with taxes and fees
This historic hotel's 7 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Enjoy the seasonal outdoor pool and perks like free ...
8.4/10 Very Good! (1,037 reviews)
Great

Reviewed on Nov 5, 2025

Opens in a new windowSt. Louis Union Station Hotel, Curio Collection by Hilton
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
3550 Samuel Sheppard Drive, St. Louis, MO
$127 nightly
The price is $150 total per night from Nov 13 to Nov 14
$150 total
Nov 13 - Nov 14
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. ...
8.8/10 Excellent! (1,015 reviews)
Book this hotel! My husband and I have traveled the world. This hotel is spectacular in every way. We asked for a corner room and the front desk accommodated us. It actually had a living room, kitchen and dining table seperate from the bedroom. The art throughout the hotel was an art museum in itself. ...

Reviewed on Nov 7, 2025

Opens in a new windowAngad Arts Hotel St. Louis, Tapestry Collection by Hilton
The Cheshire

The Cheshire

4 out of 5
6300 Clayton Rd, Richmond Heights, MO
$128 nightly
The price is $152 total per night from Nov 27 to Nov 28
$152 total
Nov 27 - Nov 28
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
8.4/10 Very Good! (1,002 reviews)
Our room was very nice. The staff were always willing to be helpful. Breakfast was amazing! With the added perk of Starbucks in a cosy, quaint coffeeshop as part of the Cheshire. Our stay was perfect.

Reviewed on Nov 4, 2025

Opens in a new windowThe Cheshire
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street, St. Louis, MO
$152 nightly
The price is $178 total per night from Nov 21 to Nov 22
$178 total
Nov 21 - Nov 22
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9/10 Wonderful! (1,445 reviews)
Staff was amazing

Reviewed on Nov 9, 2025

Opens in a new window21C Museum Hotel St Louis
DoubleTree by Hilton St. Louis Airport

DoubleTree by Hilton St. Louis Airport

4 out of 5
4505 Woodson Road, St. Louis, MO
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $139 total per night from Dec 1 to Dec 2
$139 total
Dec 1 - Dec 2
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Bring the family and enjoy the arcade/game room and kid-friendly dining. There's no skimping ...
7.8/10 Good! (837 reviews)
Everything was great. I’m a frequent and never had issues.

Reviewed on Oct 29, 2025

Opens in a new windowDoubleTree by Hilton St. Louis Airport
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road, St. Louis, MO
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $138 total per night from Nov 21 to Nov 22
$138 total
Nov 21 - Nov 22
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
8.4/10 Very Good! (1,033 reviews)
Room was clean, and staff were pleasant and informative.

Reviewed on Nov 6, 2025

Opens in a new windowRenaissance St. Louis Airport Hotel
Marriott St. Louis Grand

Marriott St. Louis Grand

4 out of 5
800 Washington Ave, St. Louis, MO
$127 nightly
The price is $151 total per night from Nov 23 to Nov 24
$151 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8/10 Very Good! (1,002 reviews)
Stay for one day with family and property is good

Reviewed on Oct 25, 2025

Opens in a new windowMarriott St. Louis Grand
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $177 total per night from Nov 20 to Nov 21
$177 total
Nov 20 - Nov 21
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
9.2/10 Wonderful! (1,073 reviews)
Beautiful hotel! Housekeeping was OUTSTANDING!!! Check-in was seamless, they literally welcomed me by name with out asking my name when I came in because I did an early check-in! Made me feel quite special! Awesome restaurant with beautiful and good drinks! We will stay there again!

Reviewed on Nov 8, 2025

Opens in a new windowLive by Loews - St.Louis
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4 Star Hotels St. Louis

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in St. Louis 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in St. Louis will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in St. Louis, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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