Explore top 2026 4 Star Hotels in St. Louis

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Top St. Louis 4 Star hotels

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $169 total per night from Jun 28 to Jun 29
$169 total
Jun 28 - Jun 29
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
8.6/10 Excellent! (4,129 reviews)
"One of the worst hotels I've ever stayed at. With the brand recognition this hotel has I expected much more. Not anything for free, but I definitely expect it better service given the brand name of the hotel. Inconsistent stories from the staff. Calling multiple times to the front desk just to get ..."

Reviewed on Jun 23, 2026

Opens in a new windowHyatt Regency St. Louis at The Arch
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $158 total per night from Jul 9 to Jul 10
$158 total
Jul 9 - Jul 10
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
8.4/10 Very Good! (1,097 reviews)
"Always a great experience while staying there..."

Reviewed on Jun 22, 2026

Opens in a new windowRenaissance St. Louis Airport Hotel
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $199 total per night from Jul 5 to Jul 6
$199 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.8/10 Excellent! (732 reviews)
"The pool is not heated and the pool area is shaded until 12:30. Towels at pool and in the room are thin and rough."

Reviewed on Jun 21, 2026

Opens in a new windowLe Méridien St. Louis Clayton
 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

4.5 out of 5
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$200 nightly
The price is $236 total per night from Jun 30 to Jul 1
$236 total
Jun 30 - Jul 1
Total with taxes and fees
This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
9/10 Wonderful! (1,007 reviews)
"Beautiful Hotel. Lots of history. St. Louis has so much to offer."

Reviewed on Jun 23, 2026

Opens in a new window The Royal Sonesta Chase Park Plaza St. Louis
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $173 total per night from Jul 19 to Jul 20
$173 total
Jul 19 - Jul 20
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9/10 Wonderful! (1,924 reviews)
"our toilet literally did not flush/work once during our 4-day stay. everyday became a ritual to speak to staff at front desk (attentive), but never resolved issue. we wound up having to use the bathroom in the lobby area everyday . staff would send engineering staff everyday, and the toilet never ..."

Reviewed on Jun 23, 2026

Opens in a new window21C Museum Hotel St Louis
Marriott St. Louis Grand

Marriott St. Louis Grand

4 out of 5
800 Washington Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $181 total per night from Jul 16 to Jul 17
$181 total
Jul 16 - Jul 17
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.2/10 Very Good! (1,007 reviews)
"Everything was wonderful."

Reviewed on Jun 22, 2026

Opens in a new windowMarriott St. Louis Grand
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
$159 nightly
The price is $189 total per night from Jun 28 to Jun 29
$189 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
9.4/10 Exceptional! (1,221 reviews)
"Great location for a ball game"

Reviewed on Jun 23, 2026

Opens in a new windowLive by Loews - St.Louis
River City Casino & Hotel

River City Casino & Hotel

4 out of 5
777 River City Casino Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $108 total per night from Jun 29 to Jun 30
$108 total
Jun 29 - Jun 30
Total with taxes and fees
This hotel features a casino, a nightclub, and 5 restaurants. Traveling on business? Take advantage of the business center, conference center, and conference ...
9.2/10 Wonderful! (1,631 reviews)
"Great location nice rooms"

Reviewed on Jun 23, 2026

Opens in a new windowRiver City Casino & Hotel
Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark

4 out of 5
1 S Broadway St. Louis MO
Fully refundableReserve now, pay when you stay
$171 nightly
The price is $204 total per night from Jun 30 to Jul 1
$204 total
Jun 30 - Jul 1
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an indoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
7.6/10 Good! (1,173 reviews)
"There were stains on the curtains and ac didn’t work in one room and barely work in the room we got moved to and didn’t look like the pictures on the app"

Reviewed on Jun 22, 2026

Opens in a new windowHilton St. Louis at the Ballpark
The Cheshire

The Cheshire

4 out of 5
6300 Clayton Rd Richmond Heights MO
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $191 total per night from Jun 28 to Jun 29
$191 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
8.8/10 Excellent! (1,005 reviews)
"Cute place to stay but definitely needs TLC. The restaurant on site was delicious and loved the location."

Reviewed on Jun 23, 2026

Opens in a new windowThe Cheshire
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4 Star Hotels St. Louis

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in St. Louis 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in St. Louis will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in St. Louis, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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