Explore top 2026 4 Star Hotels in Lafayette Square

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Oct 23 - Oct 25
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Top Lafayette Square 4 Star hotels

Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $138 total per night from Nov 15 to Nov 16
$138 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
Opens in a new windowRenaissance St. Louis Airport Hotel
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $158 total per night from Oct 30 to Oct 31
$158 total
Oct 30 - Oct 31
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
8.6/10 Excellent! (4,372 reviews)
"Room 1X53 had a nice partial view of the Arch and a welcoming sunrise. The hotel was busy with guests, but grand lobby and the hotel overall where well adapted to the daily traffic and the vibe of downtown St. Louis. This is one of my favorite places to stay when I am in town as it’s very easy to ..."

Reviewed on Oct 18, 2026

Opens in a new windowHyatt Regency St. Louis at The Arch
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $173 total per night from Nov 15 to Nov 16
$173 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Opens in a new window21C Museum Hotel St Louis
The Cheshire

The Cheshire

4 out of 5
6300 Clayton Rd Richmond Heights MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $176 total per night from Oct 25 to Oct 26
$176 total
Oct 25 - Oct 26
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Opens in a new windowThe Cheshire
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $165 total per night from Nov 15 to Nov 16
$165 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
9.4/10 Exceptional! (1,351 reviews)
"Great place to stay."

Reviewed on Oct 18, 2026

Opens in a new windowLive by Loews - St.Louis
The Westin St. Louis

The Westin St. Louis

4.5 out of 5
811 Spruce St St. Louis MO
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $153 total per night from Nov 15 to Nov 16
$153 total
Nov 15 - Nov 16
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...
8.6/10 Excellent! (1,004 reviews)
"I stayed at this property 20+ years ago and it was beautiful. This time, we stayed in the governor’s suite and what a letdown. Ratty, broken down sofa, peeling wallpaper in the bathroom, no electric services on one side of the bed, only one glass in the room. No mini bar, and no cold water bottles. ..."

Reviewed on Oct 19, 2026

Opens in a new windowThe Westin St. Louis
The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

4.5 out of 5
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$186 nightly
The price is $219 total per night from Nov 15 to Nov 16
$219 total
Nov 15 - Nov 16
Total with taxes and fees
This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
Opens in a new window The Royal Sonesta Chase Park Plaza St. Louis
River City Casino & Hotel

River City Casino & Hotel

4 out of 5
777 River City Casino Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $136 total per night from Oct 27 to Oct 28
$136 total
Oct 27 - Oct 28
Total with taxes and fees
This hotel features a casino, a nightclub, and 5 restaurants. Traveling on business? Take advantage of the business center, conference center, and conference ...
Opens in a new windowRiver City Casino & Hotel
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
3550 Samuel Sheppard Drive St. Louis MO
Fully refundableReserve now, pay when you stay
$126 nightly
The price is $149 total per night from Oct 25 to Oct 26
$149 total
Oct 25 - Oct 26
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. ...
8.8/10 Excellent! (1,175 reviews)
"Exceeded our expectations."

Reviewed on Oct 18, 2026

Opens in a new windowAngad Arts Hotel St. Louis, Tapestry Collection by Hilton
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
$163 nightly
The price is $190 total per night from Nov 17 to Nov 18
$190 total
Nov 17 - Nov 18
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and outdoor pool, and unwind with a drink at the poolside ...
Opens in a new windowAmeristar Casino Resort and Spa
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Lafayette Square hotel reviews by fellow wanderers

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Very nice place to stay. Great service"
A verified traveler stayed at Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay

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