Explore top 2026 4 Star Hotels in Lafayette Square

Name: 21C Museum Hotel St Louis
Price range: $173 total
Rating: 9

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Top Lafayette Square 4 Star hotels

Hyatt Regency St. Louis at The Arch

315 Chestnut St St. Louis MO

Fully refundableReserve now, pay when you stay

$152 nightly

$179 total

Jul 31 - Aug 1

Total with taxes and fees

This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...

8.6/10 Excellent! (4,136 reviews)

"Clean quiet rooms. Good facilities"

Reviewed on Jul 19, 2026

Moonrise Hotel

6177 Delmar Blvd St. Louis MO

Fully refundableReserve now, pay when you stay

$179 nightly

$213 total

Jul 20 - Jul 21

Total with taxes and fees

The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the 24-hour business ...

St. Louis Union Station Hotel, Curio Collection by Hilton

1820 Market Street St. Louis MO

Fully refundableReserve now, pay when you stay

$169 nightly

$201 total

Aug 6 - Aug 7

Total with taxes and fees

This luxury hotel's 7 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Enjoy the seasonal outdoor pool and perks like free WiFi. ...

8.8/10 Excellent! (1,001 reviews)

"The Koi fish pond was fantastic. The hotel needs updated. In our room the toliet was leaking on the floor. Then for parking was $45 for 12 hours parking, it was ridiculous"

Reviewed on Jul 17, 2026

The Royal Sonesta Chase Park Plaza St. Louis

212 N Kingshighway St. Louis MO

Fully refundableReserve now, pay when you stay

$198 nightly

$234 total

Aug 3 - Aug 4

Total with taxes and fees

This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...

Live by Loews - St.Louis

799 Clark ave St. Louis MO

$159 nightly

$189 total

Aug 3 - Aug 4

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...

9.4/10 Exceptional! (1,251 reviews)

"Excellent stay! Really enjoyed everything. It was very clean, great view, nice staff!"

Reviewed on Jul 19, 2026

The Westin St. Louis

811 Spruce St St. Louis MO

Fully refundableReserve now, pay when you stay

$140 nightly

$164 total

Aug 6 - Aug 7

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...

8.6/10 Excellent! (1,003 reviews)

"Great experience at the Westin. Just a few steps away from Busch field to watch the Braves vs the Cardinals!"

Reviewed on Jul 18, 2026

Hilton St. Louis Frontenac

1335 S Lindbergh Blvd Frontenac MO

Fully refundableReserve now, pay when you stay

$147 nightly

$171 total

Jul 26 - Jul 27

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

Renaissance St. Louis Airport Hotel

9801 Natural Bridge Road St. Louis MO

Fully refundableReserve now, pay when you stay

$115 nightly

$135 total

Aug 1 - Aug 2

Total with taxes and fees

This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...

8.4/10 Very Good! (1,114 reviews)

"Super fast service at the front desk…The fitness room was top tier…the room was very clean and the shower was hot"

Reviewed on Jul 19, 2026

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

3550 Samuel Sheppard Drive St. Louis MO

Fully refundableReserve now, pay when you stay

$107 nightly

$126 total

Aug 3 - Aug 4

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. ...

9/10 Wonderful! (1,079 reviews)

"Very interesting art hotel with sculptures and paintings in foyer and other public areas. I had the yellow room, very beautiful and functional. The reception and foyer are on the 12th floor, which is a bit unusual, but why not! The hotel‘s location is fabulous: theater district, USL campus, galleries ..."

Reviewed on Jul 19, 2026

21C Museum Hotel St Louis

1528 Locust street St. Louis MO

Fully refundableReserve now, pay when you stay

$148 nightly

$173 total

Aug 9 - Aug 10

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

9/10 Wonderful! (1,975 reviews)

"Such a unique space! Art is emeshed throughout the entire building, creating a warm, inviting space (and a ton of photo ops). Every staff member we encountered was kind, engaging, and helpful. Having access to the pool and fitness center was wonderful for our stay. Breakfast at Good Press was 10/10. ..."

Reviewed on Jul 18, 2026

Don't see what you're looking for?

See all available properties in Lafayette Square

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.