Find a Hotel in Central West End

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top hotels in Central West End

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $107 total per night from Nov 18 to Nov 19
$107 total
Nov 18 - Nov 19
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
"I stay at this hotel Everytime I'm in St. Louis. The staff is friendly and helpful, and the hotel is well maintained and convenient."

Reviewed on Nov 13, 2026

Opens in a new windowPear Tree Inn St. Louis Airport
The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

4.5 out of 5
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $188 total per night from Nov 22 to Nov 23
$188 total
Nov 22 - Nov 23
Total with taxes and fees
This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
"From the lobby to the room; staff was friendly, and place was immaculate!"

Reviewed on Nov 14, 2026

Opens in a new window The Royal Sonesta Chase Park Plaza St. Louis
Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG

3.5 out of 5
4630 Lindell St. Louis MO
Fully refundable
$125 nightly
The price is $148 total per night from Dec 13 to Dec 14
$148 total
Dec 13 - Dec 14
Total with taxes and fees
This Art Deco hotel features 4 restaurants, a bar/lounge, and a 24-hour gym. Business travelers can take advantage of the free WiFi in public areas. Self parking, ...
"Overall, our stay was okay. I would have liked a microwave in my room, an ice machine close by, and an explanation of the "energy" fee on my final invoice. Also, that location should not charge for parking. I felt "nickel and dimed" to death after this experience. Also, Housekeeping failed to put ..."

Reviewed on Nov 12, 2026

Opens in a new windowHotel Indigo St Louis - Central West End by IHG
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $122 total per night from Dec 6 to Dec 7
$122 total
Dec 6 - Dec 7
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"Great stay"

Reviewed on Nov 13, 2026

Opens in a new windowClayton Plaza Hotel & Extended Stay
The West End

The West End

2 out of 5
4215 Lindell Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $103 total per night from Nov 15 to Nov 16
$103 total
Nov 15 - Nov 16
Total with taxes and fees
A 24-hour gym, self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Express check-out, luggage storage, and barbecue ...
Opens in a new windowThe West End
Aloft by Marriott St Louis Central West End

Aloft by Marriott St Louis Central West End

3 out of 5
4245 Duncan Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $133 total per night from Nov 16 to Nov 17
$133 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel features an indoor pool and a bar/lounge. WiFi in public areas is free. Valet parking, a 24-hour business center, and a coffee shop are also ...
Opens in a new windowAloft by Marriott St Louis Central West End
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $158 total per night from Dec 13 to Dec 14
$158 total
Dec 13 - Dec 14
Total with taxes and fees
2 hot tubs, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in ...
Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $126 total per night from Nov 26 to Nov 27
$126 total
Nov 26 - Nov 27
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
Opens in a new windowHyatt Regency St. Louis at The Arch
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
3550 Samuel Sheppard Drive St. Louis MO
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $122 total per night from Nov 22 to Nov 23
$122 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. ...
Opens in a new windowAngad Arts Hotel St. Louis, Tapestry Collection by Hilton
Don't see what you're looking for?
See all available properties in Central West End
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Central West End Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Central West End area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Central West End to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Central West End are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Explore More Ways to Travel with Travelocity