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Top hotels in Central West End

The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

4.5 out of 5
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$209 nightly
The price is $246 total per night from Jun 28 to Jun 29
$246 total
Jun 28 - Jun 29
Total with taxes and fees
This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
"This is a beautiful hotel, clean and comfortable room. The room cleanliness and expertise of the room staff was excellent. However, my very first impression was very poor. I pulled up to the entrance (of which apparently only valet is allowed to drive/park at because I was promptly approached and ..."

Reviewed on Jun 17, 2026

Opens in a new window The Royal Sonesta Chase Park Plaza St. Louis
AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End

4 out of 5
215 YORK AVENUE St. Louis MO
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $169 total per night from Jul 11 to Jul 12
$169 total
Jul 11 - Jul 12
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
"Highly recommend this Hotel was in the middle of their medical center. They were so friendly when I arrived allowed me to check in early with no hassles the runs were extremely clean.! If I pass through this town again, I would Definitely say again!"

Reviewed on Jun 10, 2026

Opens in a new windowAC Hotel St. Louis Central West End
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $117 total per night from Jun 21 to Jun 22
$117 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"Such a great stay! Great neighborhood. Great hotel. Great staff. Great breakfast. I’ll definitely book again."

Reviewed on Jun 19, 2026

Opens in a new windowClayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $143 total per night from Jun 28 to Jun 29
$143 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
"Room was clean staff were lovely"

Reviewed on Jun 17, 2026

Opens in a new windowPear Tree Inn St. Louis Near Union Station
The West End

The West End

2 out of 5
4215 Lindell Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $142 total per night from Jun 21 to Jun 22
$142 total
Jun 21 - Jun 22
Total with taxes and fees
A 24-hour gym, self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Express check-out, luggage storage, and barbecue ...
"Hands down the cleanest hotel I’ve ever stayed at. We loved it!"

Reviewed on Jun 19, 2026

Opens in a new windowThe West End
Aloft by Marriott St. Louis Cortex

Aloft by Marriott St. Louis Cortex

3 out of 5
4245 Duncan Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $133 total per night from Jun 28 to Jun 29
$133 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features an indoor pool and a bar/lounge. WiFi in public areas is free. Valet parking, a 24-hour business center, and a coffee shop are also ...
"Honestly loved it will be going back the loved the games area"

Reviewed on Jun 17, 2026

Opens in a new windowAloft by Marriott St. Louis Cortex
Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG

3.5 out of 5
4630 Lindell St. Louis MO
Fully refundable
$130 nightly
The price is $154 total per night from Jul 19 to Jul 20
$154 total
Jul 19 - Jul 20
Total with taxes and fees
This Art Deco hotel features 4 restaurants, a bar/lounge, and a 24-hour gym. Business travelers can take advantage of the free WiFi in public areas. Self parking, ...
"I enjoyed the parking garage under the hotel it was walking distance to lots of cute restaurants and stores !! Super cute rooms and comfortable beds"

Reviewed on Jun 16, 2026

Opens in a new windowHotel Indigo St Louis - Central West End by IHG
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $169 total per night from Jun 28 to Jun 29
$169 total
Jun 28 - Jun 29
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
"I loved the location of the property and the view of the St. Louis Arch. The convenience of having a full service Starbucks on property was great."

Reviewed on Jun 19, 2026

Opens in a new windowHyatt Regency St. Louis at The Arch
DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park

4 out of 5
4550 Forest Park Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $154 total per night from Jul 2 to Jul 3
$154 total
Jul 2 - Jul 3
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Self parking, ...
"Rooms are comfortable, and the beds are incredible!!"

Reviewed on Jun 19, 2026

Opens in a new windowDoubleTree by Hilton St. Louis Forest Park
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Central West End Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Central West End area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Central West End to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Central West End are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Central West End hotel reviews by fellow wanderers

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

5 out of 5
Posted 5 hours ago
Travelocity Verified Review
"I loved the location of the property and the view of the St. Louis Arch. The convenience of having a full service Starbucks on property was great."
A verified traveler stayed at Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch

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