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Top hotels in Central West End

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $168 total per night from Feb 18 to Feb 19
$168 total
Feb 18 - Feb 19
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Room was spotless. Only problem was the shower pin would not stay up so we had to take baths.

Reviewed on Feb 11, 2026

Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $106 total per night from Feb 18 to Feb 19
$106 total
Feb 18 - Feb 19
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
Clean room. Great staff.

Reviewed on Feb 12, 2026

Opens in a new windowPear Tree Inn St. Louis Airport
 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

4.5 out of 5
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$200 nightly
The price is $236 total per night from Feb 22 to Feb 23
$236 total
Feb 22 - Feb 23
Total with taxes and fees
This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
Wonderful

Reviewed on Feb 9, 2026

Opens in a new window The Royal Sonesta Chase Park Plaza St. Louis
AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End

4 out of 5
215 YORK AVENUE St. Louis MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $175 total per night from Feb 22 to Feb 23
$175 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
Staff and they all helped dig us out of the snow!!!!

Reviewed on Feb 7, 2026

Opens in a new windowAC Hotel St. Louis Central West End
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $162 total per night from Feb 22 to Feb 23
$162 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Everything was superlative. Staff, hotel, room, pool.

Reviewed on Feb 11, 2026

Opens in a new window21C Museum Hotel St Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $123 total per night from Feb 26 to Feb 27
$123 total
Feb 26 - Feb 27
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Cleanliness, staff nice

Reviewed on Feb 7, 2026

Opens in a new windowClayton Plaza Hotel & Extended Stay
Aloft St. Louis Cortex

Aloft St. Louis Cortex

3 out of 5
4245 Duncan Avenue St. Louis MO
$121 nightly
The price is $141 total per night from Feb 22 to Feb 23
$141 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features an indoor pool and a bar/lounge. WiFi in public areas is free. A 24-hour business center, a coffee shop, and a snack bar/deli are also on ...
Friendly staff that greeted me at check-in

Reviewed on Jan 26, 2026

Opens in a new windowAloft St. Louis Cortex
The West End

The West End

2 out of 5
4215 Lindell Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $131 total per night from Feb 15 to Feb 16
$131 total
Feb 15 - Feb 16
Total with taxes and fees
A 24-hour gym, self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. A garden and express check-out are also ...
The room was comfortable and clean!! Even though it’s a non-smoking establishment, there are signs of previous smoking in the bathroom as the countertop had cigarette burns in multiple places. There was no smell of smoke when I occupied the room so that was a plus. My only complaint is the time it ...

Reviewed on Feb 11, 2026

Opens in a new windowThe West End
DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park

4 out of 5
4550 Forest Park Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $161 total per night from Mar 2 to Mar 3
$161 total
Mar 2 - Mar 3
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Self parking, ...
Clean, quiet, and the staff were great

Reviewed on Feb 6, 2026

Opens in a new windowDoubleTree by Hilton St. Louis Forest Park
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Central West End Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Central West End area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Central West End to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Central West End are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Central West End hotel reviews by fellow wanderers

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