Book Hotels in St. Ann, MO

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Top St. Ann hotels

Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

3 out of 5
201 S 20th St St. Louis MO
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $161 total per night from Sep 29 to Sep 30
$161 total
Sep 29 - Sep 30
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
"Kickback was great"

Reviewed on Sep 24, 2026

Opens in a new windowDrury Plaza Hotel St. Louis Union Station
Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport

3 out of 5
10820 Pear Tree Lane St. Ann MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $110 total per night from Sep 27 to Sep 28
$110 total
Sep 27 - Sep 28
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
"Adrienne was so friendly and helpful with checking in. Also shuttle service was terrific!"

Reviewed on Sep 22, 2026

Opens in a new windowWingate by Wyndham St. Louis Airport
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $173 total per night from Oct 18 to Oct 19
$173 total
Oct 18 - Oct 19
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
"A bit off the beating path, but well worth the walk or ride there. Unfortunately I was only there for a day, so missed out on many of the amenities. But will definitely book here again and take advantage of all they have to offer. P.S. The room are well kept, roomy, and comfortable."

Reviewed on Sep 24, 2026

Opens in a new window21C Museum Hotel St Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $110 total per night from Oct 11 to Oct 12
$110 total
Oct 11 - Oct 12
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"We had an excellent stay at this hotel. Room was quite spacious with extra seating, coffee maker with ceramic mugs, quiet environment. The breakfast room featured an omelet and waffle station. The location is excellent for exploring many of the highlights of St. Louis, including Forest Park. The ..."

Reviewed on Sep 24, 2026

Opens in a new windowClayton Plaza Hotel & Extended Stay
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
3550 Samuel Sheppard Drive St. Louis MO
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $139 total per night from Oct 5 to Oct 6
$139 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. ...
"Excellent roof top bar!!!"

Reviewed on Sep 24, 2026

Opens in a new windowAngad Arts Hotel St. Louis, Tapestry Collection by Hilton
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $158 total per night from Oct 2 to Oct 3
$158 total
Oct 2 - Oct 3
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
"Best place to stay in St Louis. Excellent location with a Starbucks and Chris Ruth Steakhouse on property! The Arch is right outside the hotel doors! Busch Stadium is a 10 minute walk! Property was shiny and clean! Beds and pillows were awesome!! Loved!!"

Reviewed on Sep 24, 2026

Opens in a new windowHyatt Regency St. Louis at The Arch
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $138 total per night from Oct 4 to Oct 5
$138 total
Oct 4 - Oct 5
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
"We had a great experience at the hotel. The Internet you do have to pay extra for if you hook up your devices. Also parking is about $25 a night before taxes. All and all a good experience"

Reviewed on Sep 24, 2026

Opens in a new windowRenaissance St. Louis Airport Hotel
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $106 total per night from Oct 4 to Oct 5
$106 total
Oct 4 - Oct 5
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
Opens in a new windowPear Tree Inn St. Louis Airport
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $158 total per night from Oct 2 to Oct 3
$158 total
Oct 2 - Oct 3
Total with taxes and fees
2 hot tubs, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in ...
Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap St. Ann hotels

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln St. Ann MO
$90 nightly
The price is $106 total per night from Oct 4 to Oct 5
$106 total
Oct 4 - Oct 5
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

St. Ann Hotel & Travel Guide\n

Traveling to St. Ann? There is a range of accommodation options from which you can choose. Right now, Travelocity is where modern travelers can compare 69 places to base yourself within a 6-mile (10-kilometer) radius of St. Ann's heart.

For those times when you and your traveling partner are after a place to stay no more than 2 miles (3 kilometers) from the middle of St. Ann, Marriott St. Louis Airport and Embassy Suites St. Louis - Airport are perfect.

The Four Seasons Hotel St Louis is 13 miles (20 kilometers) outside of downtown St. Ann. Another accommodation option is the The Ritz-Carlton, St. Louis, which is about 6 miles (10 kilometers) away. Other possible Travelocity-listed accommodation options are the Grand Center Inn and the Ameristar Casino Resort and Spa.

When you have some spare time, adventurous explorers could explore more of St. Louis - Northeast Missouri. Get ready to discover the sights of St. Louis - Northeast Missouri's prairies. You could also head to some of the area's history museums. Common things to do in this area of United States of America include mountain biking.

Looking for activities? Spend some time exploring The Gardens at SIUE and Edwardsville Arts Center, which you'll find in North MetroEast, 20 miles (32 kilometers) to the east of St. Ann. Should you wish to spend a few nights in North MetroEast, be sure to check out the Hampton Inn Suites St LouisEdwardsville and Comfort Inn and Conference Center. Alternatively, you could stay in Downtown St. Louis, 12 miles (19 kilometers) southeast of St. Ann, where you can choose from the The Westin St. Louis and Embassy Suites St. Louis - Downtown. When you visit Downtown St. Louis, you might like to visit the Old Post Office and Scott Joplin House State Historic Site.

When enjoying sport is on your bucket list for St. Ann, visit Busch Stadium, which is 13 miles (20 kilometers) to the southeast of St. Ann. Those wanting to book a Travelocity-listed hotel in the area surrounding the game can explore the Residence Inn by Marriott St Louis Downtown or the Hilton St. Louis at the Ballpark.

When you're traveling through Lambert-St. Louis International Airport and desire to stay in the area, check out Holiday Inn St. Louis-Airport or Hampton Inn St Louis-Airport.

Frequently asked questions

What are the top kid-friendly hotels in St. Ann?
Take some of the challenges out of traveling with young ones by booking a family-friendly hotel in St. Ann. From entertaining amenities to services that bring a smile, these stays come with perks that'll help make your visit run like a dream: Crowne Plaza St. Louis Airport, an IHG Hotel will help make your getaway the most memorable one yet. It comes with a variety of conveniences geared toward families, such as a swimming pool and a pillowtop mattress. MainStay Suites St Louis Airport is also a great choice. After a big day of exploring, come back home to your comfortable room and amenities like complimentary breakfast and front desk services.
Where can I find cheap hotels in St. Ann?
At Travelocity you'll find really nice hotels in St. Ann at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near St. Ann rather than in St. Ann. We may find you even better rates, too.
How do I find the best St. Ann hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in St. Ann then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in St. Ann?
The cheapest hotel in St. Ann is $106. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in St. Ann?
There are 1,987 hotels in St. Ann on Travelocity.
What are the best hotels in St. Ann?
St. Ann has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in St. Ann for you!
When is the best time to visit St. Ann?
If you want the joy of a fun-filled trip in peak season, visit St. Ann during March, August and October. If you'd prefer the peace of off-season, book a stay during quieter months, such as November, December and January.
When is the cheapest time to stay in St. Ann?
Based on historic data is usually the cheapest month to visit St. Ann. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in St. Ann?
There are multiple hotels in St. Ann that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to St. Ann. We have plenty of kid-friendly hotels in St. Ann to choose from on Travelocity!
Why book a hotel in St. Ann through Travelocity?
Because we have the top hotels in St. Ann! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in St. Ann on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent St. Ann hotel reviews by fellow wanderers

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

4 out of 5
Posted less than an hour ago
Travelocity Verified Review
"We had an excellent stay at this hotel. Room was quite spacious with extra seating, coffee maker with ceramic mugs, quiet environment. The breakfast room featured an omelet and waffle station. The location is excellent for exploring many of the highlights of St. Louis, including Forest Park. The hotel is surrounded by great restaurants within walking distance, and the airport is about 12 minutes away. We would definitely stay there again."
A verified traveler stayed at Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay

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